Centrosomal protein POC5

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AT47_LEIMU

TriTrypDb:

LmxM.36.2690

Length:

339

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	10
GO:0005813	centrosome	3	1
GO:0005814	centriole	5	10
GO:0005815	microtubule organizing center	2	1
GO:0043226	organelle	2	10
GO:0043228	non-membrane-bounded organelle	3	10
GO:0043229	intracellular organelle	3	10
GO:0043232	intracellular non-membrane-bounded organelle	4	10
GO:0110165	cellular anatomical entity	1	10

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Expansion

Sequence features

E9AT47

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AT47

Function

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Biological processes
Term	Name	Level	Count
GO:0007049	cell cycle	2	10
GO:0009987	cellular process	1	10

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	218	222	PF00656	0.541
CLV_NRD_NRD_1	110	112	PF00675	0.432
CLV_NRD_NRD_1	116	118	PF00675	0.461
CLV_NRD_NRD_1	120	122	PF00675	0.420
CLV_NRD_NRD_1	41	43	PF00675	0.476
CLV_NRD_NRD_1	63	65	PF00675	0.456
CLV_PCSK_FUR_1	117	121	PF00082	0.525
CLV_PCSK_FUR_1	150	154	PF00082	0.426
CLV_PCSK_KEX2_1	110	112	PF00082	0.421
CLV_PCSK_KEX2_1	116	118	PF00082	0.428

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I2V9	Leptomonas seymouri	49%	99%
A0A1X0NKY4	Trypanosomatidae	27%	82%
A0A3Q8IKC6	Leishmania donovani	94%	100%
A4HPD7	Leishmania braziliensis	81%	100%
A4ICH6	Leishmania infantum	94%	100%
D0A3J5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	93%
Q4Q1F1	Leishmania major	91%	100%
V5BK99	Trypanosoma cruzi	28%	90%

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