Putative caltractin

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Putative caltractin

Gene product:

caltractin, putative

Species:

Leishmania mexicana

UniProt:

E9AT20_LEIMU

TriTrypDb:

LmxM.36.2430

Length:

265

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9AT20

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AT20

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	4
GO:0005509	calcium ion binding	5	4
GO:0043167	ion binding	2	4
GO:0043169	cation binding	3	4
GO:0046872	metal ion binding	4	4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	93	97	PF00656	0.752
CLV_NRD_NRD_1	182	184	PF00675	0.568
CLV_NRD_NRD_1	216	218	PF00675	0.530
CLV_NRD_NRD_1	259	261	PF00675	0.560
CLV_PCSK_KEX2_1	216	218	PF00082	0.530
CLV_PCSK_SKI1_1	12	16	PF00082	0.432
CLV_PCSK_SKI1_1	183	187	PF00082	0.589
DEG_APCC_DBOX_1	44	52	PF00400	0.528
DEG_SPOP_SBC_1	131	135	PF00917	0.553
DOC_MAPK_gen_1	42	51	PF00069	0.535
DOC_PP4_FxxP_1	158	161	PF00568	0.739
DOC_USP7_MATH_1	112	116	PF00917	0.589
DOC_USP7_MATH_1	131	135	PF00917	0.810
DOC_USP7_MATH_1	145	149	PF00917	0.559
DOC_USP7_MATH_1	151	155	PF00917	0.485
DOC_WW_Pin1_4	122	127	PF00397	0.782
DOC_WW_Pin1_4	140	145	PF00397	0.602
DOC_WW_Pin1_4	157	162	PF00397	0.617
LIG_14-3-3_CanoR_1	33	39	PF00244	0.562
LIG_14-3-3_CanoR_1	42	52	PF00244	0.500
LIG_APCC_ABBA_1	15	20	PF00400	0.442
LIG_BIR_II_1	1	5	PF00653	0.494
LIG_BRCT_BRCA1_1	2	6	PF00533	0.553
LIG_FHA_1	131	137	PF00498	0.735
LIG_FHA_1	195	201	PF00498	0.468
LIG_FHA_1	242	248	PF00498	0.465
LIG_FHA_1	90	96	PF00498	0.651
LIG_FHA_2	225	231	PF00498	0.498
LIG_FHA_2	249	255	PF00498	0.463
LIG_FHA_2	91	97	PF00498	0.708
LIG_LIR_Gen_1	175	185	PF02991	0.431
LIG_LIR_Gen_1	197	206	PF02991	0.463
LIG_LIR_Gen_1	250	259	PF02991	0.522
LIG_LIR_Nem_3	13	18	PF02991	0.376
LIG_LIR_Nem_3	175	180	PF02991	0.395
LIG_LIR_Nem_3	197	201	PF02991	0.460
LIG_LIR_Nem_3	203	209	PF02991	0.437
LIG_LIR_Nem_3	233	238	PF02991	0.477
LIG_LIR_Nem_3	250	255	PF02991	0.508
LIG_Rb_pABgroove_1	229	237	PF01858	0.481
LIG_SH2_STAP1	18	22	PF00017	0.387
LIG_SH2_STAP1	190	194	PF00017	0.453
LIG_SH2_STAP1	196	200	PF00017	0.444
LIG_SH2_STAP1	54	58	PF00017	0.367
LIG_SH2_STAT5	196	199	PF00017	0.591
LIG_SH2_STAT5	36	39	PF00017	0.489
LIG_SH3_3	133	139	PF00018	0.731
LIG_SH3_3	141	147	PF00018	0.699
LIG_TRAF2_1	189	192	PF00917	0.531
LIG_TRAF2_1	27	30	PF00917	0.336
LIG_WRC_WIRS_1	249	254	PF05994	0.455
MOD_CK1_1	105	111	PF00069	0.520
MOD_CK1_1	117	123	PF00069	0.656
MOD_CK1_1	124	130	PF00069	0.639
MOD_CK1_1	143	149	PF00069	0.509
MOD_CK1_1	160	166	PF00069	0.736
MOD_CK1_1	250	256	PF00069	0.511
MOD_CK1_1	79	85	PF00069	0.685
MOD_CK2_1	117	123	PF00069	0.713
MOD_CK2_1	186	192	PF00069	0.541
MOD_CK2_1	224	230	PF00069	0.513
MOD_CK2_1	24	30	PF00069	0.325
MOD_GlcNHglycan	147	150	PF01048	0.611
MOD_GlcNHglycan	19	25	PF01048	0.412
MOD_GlcNHglycan	81	84	PF01048	0.674
MOD_GSK3_1	102	109	PF00069	0.585
MOD_GSK3_1	117	124	PF00069	0.727
MOD_GSK3_1	125	132	PF00069	0.721
MOD_GSK3_1	145	152	PF00069	0.507
MOD_GSK3_1	20	27	PF00069	0.389
MOD_GSK3_1	237	244	PF00069	0.481
MOD_GSK3_1	72	79	PF00069	0.611
MOD_GSK3_1	85	92	PF00069	0.703
MOD_N-GLC_1	117	122	PF02516	0.618
MOD_NEK2_1	1	6	PF00069	0.691
MOD_NEK2_1	102	107	PF00069	0.702
MOD_NEK2_1	194	199	PF00069	0.444
MOD_PIKK_1	125	131	PF00454	0.722
MOD_PIKK_1	151	157	PF00454	0.762
MOD_PIKK_1	72	78	PF00454	0.611
MOD_PIKK_1	85	91	PF00454	0.610
MOD_PKA_2	106	112	PF00069	0.676
MOD_PKA_2	121	127	PF00069	0.692
MOD_Plk_1	117	123	PF00069	0.460
MOD_Plk_1	202	208	PF00069	0.578
MOD_Plk_1	247	253	PF00069	0.446
MOD_Plk_1	97	103	PF00069	0.668
MOD_Plk_2-3	13	19	PF00069	0.373
MOD_Plk_2-3	224	230	PF00069	0.513
MOD_Plk_2-3	248	254	PF00069	0.508
MOD_Plk_4	1	7	PF00069	0.579
MOD_ProDKin_1	122	128	PF00069	0.784
MOD_ProDKin_1	140	146	PF00069	0.600
MOD_ProDKin_1	157	163	PF00069	0.616
MOD_SUMO_rev_2	4	14	PF00179	0.411
TRG_DiLeu_BaEn_1	47	52	PF01217	0.518
TRG_ENDOCYTIC_2	206	209	PF00928	0.436
TRG_ER_diArg_1	215	217	PF00400	0.522

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5G8	Leptomonas seymouri	52%	100%
A0A3S7XAY6	Leishmania donovani	92%	100%
A0A422NCF5	Trypanosoma rangeli	38%	100%
A4HPA9	Leishmania braziliensis	69%	97%
A4ICE9	Leishmania infantum	92%	100%
Q4Q1H8	Leishmania major	87%	100%