Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ASZ6_LEIMU

TriTrypDb:

LmxM.36.2190

Length:

587

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASZ6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASZ6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	283	287	PF00656	0.707
CLV_NRD_NRD_1	126	128	PF00675	0.563
CLV_NRD_NRD_1	159	161	PF00675	0.524
CLV_NRD_NRD_1	182	184	PF00675	0.483
CLV_NRD_NRD_1	205	207	PF00675	0.719
CLV_NRD_NRD_1	304	306	PF00675	0.843
CLV_NRD_NRD_1	351	353	PF00675	0.715
CLV_NRD_NRD_1	396	398	PF00675	0.461
CLV_NRD_NRD_1	471	473	PF00675	0.656
CLV_NRD_NRD_1	492	494	PF00675	0.629
CLV_NRD_NRD_1	556	558	PF00675	0.645
CLV_PCSK_FUR_1	421	425	PF00082	0.707
CLV_PCSK_KEX2_1	126	128	PF00082	0.507
CLV_PCSK_KEX2_1	182	184	PF00082	0.536
CLV_PCSK_KEX2_1	197	199	PF00082	0.669
CLV_PCSK_KEX2_1	205	207	PF00082	0.617
CLV_PCSK_KEX2_1	423	425	PF00082	0.742
CLV_PCSK_KEX2_1	471	473	PF00082	0.656
CLV_PCSK_KEX2_1	511	513	PF00082	0.728
CLV_PCSK_KEX2_1	535	537	PF00082	0.711
CLV_PCSK_PC1ET2_1	197	199	PF00082	0.698
CLV_PCSK_PC1ET2_1	423	425	PF00082	0.746
CLV_PCSK_PC1ET2_1	511	513	PF00082	0.684
CLV_PCSK_PC1ET2_1	535	537	PF00082	0.711
CLV_PCSK_SKI1_1	192	196	PF00082	0.628
CLV_PCSK_SKI1_1	205	209	PF00082	0.534
CLV_PCSK_SKI1_1	306	310	PF00082	0.670
CLV_PCSK_SKI1_1	450	454	PF00082	0.743
CLV_PCSK_SKI1_1	498	502	PF00082	0.576
CLV_PCSK_SKI1_1	562	566	PF00082	0.714
DEG_Kelch_Keap1_1	95	100	PF01344	0.727
DEG_Nend_Nbox_1	1	3	PF02207	0.539
DOC_CYCLIN_yClb3_PxF_3	579	585	PF00134	0.662
DOC_MAPK_FxFP_2	576	579	PF00069	0.672
DOC_PP4_FxxP_1	571	574	PF00568	0.689
DOC_PP4_FxxP_1	576	579	PF00568	0.697
DOC_USP7_MATH_1	138	142	PF00917	0.653
DOC_USP7_MATH_1	215	219	PF00917	0.494
DOC_USP7_MATH_1	246	250	PF00917	0.730
DOC_USP7_MATH_1	280	284	PF00917	0.709
DOC_USP7_MATH_1	467	471	PF00917	0.677
DOC_USP7_UBL2_3	309	313	PF12436	0.694
DOC_USP7_UBL2_3	494	498	PF12436	0.568
DOC_USP7_UBL2_3	511	515	PF12436	0.516
DOC_USP7_UBL2_3	550	554	PF12436	0.681
DOC_USP7_UBL2_3	558	562	PF12436	0.562
DOC_WW_Pin1_4	210	215	PF00397	0.729
DOC_WW_Pin1_4	293	298	PF00397	0.665
DOC_WW_Pin1_4	356	361	PF00397	0.715
DOC_WW_Pin1_4	435	440	PF00397	0.600
LIG_14-3-3_CanoR_1	107	111	PF00244	0.695
LIG_14-3-3_CanoR_1	131	136	PF00244	0.509
LIG_14-3-3_CanoR_1	205	214	PF00244	0.668
LIG_14-3-3_CanoR_1	298	304	PF00244	0.579
LIG_14-3-3_CanoR_1	397	402	PF00244	0.469
LIG_14-3-3_CanoR_1	493	497	PF00244	0.628
LIG_14-3-3_CanoR_1	68	77	PF00244	0.613
LIG_Actin_WH2_2	104	119	PF00022	0.533
LIG_APCC_ABBA_1	526	531	PF00400	0.535
LIG_BIR_III_4	434	438	PF00653	0.710
LIG_CtBP_PxDLS_1	52	56	PF00389	0.536
LIG_EVH1_1	571	575	PF00568	0.719
LIG_EVH1_1	578	582	PF00568	0.630
LIG_FHA_1	130	136	PF00498	0.487
LIG_FHA_1	23	29	PF00498	0.713
LIG_FHA_1	262	268	PF00498	0.682
LIG_FHA_1	30	36	PF00498	0.638
LIG_FHA_1	415	421	PF00498	0.601
LIG_FHA_1	449	455	PF00498	0.496
LIG_FHA_1	499	505	PF00498	0.585
LIG_FHA_1	517	523	PF00498	0.471
LIG_FHA_2	407	413	PF00498	0.600
LIG_FHA_2	69	75	PF00498	0.764
LIG_FHA_2	84	90	PF00498	0.589
LIG_FHA_2	92	98	PF00498	0.686
LIG_LIR_Gen_1	121	130	PF02991	0.616
LIG_LIR_Gen_1	458	468	PF02991	0.573
LIG_LIR_Gen_1	495	504	PF02991	0.663
LIG_LIR_Nem_3	121	125	PF02991	0.617
LIG_LIR_Nem_3	458	463	PF02991	0.568
LIG_LIR_Nem_3	495	499	PF02991	0.656
LIG_NRBOX	220	226	PF00104	0.693
LIG_Pex14_1	492	496	PF04695	0.630
LIG_Pex14_2	251	255	PF04695	0.689
LIG_RPA_C_Fungi	467	479	PF08784	0.629
LIG_RPA_C_Plants	300	311	PF08784	0.682
LIG_SH2_CRK	496	500	PF00017	0.690
LIG_SH2_STAP1	338	342	PF00017	0.749
LIG_SH2_STAP1	496	500	PF00017	0.628
LIG_SH3_1	535	541	PF00018	0.542
LIG_SH3_2	358	363	PF14604	0.567
LIG_SH3_3	211	217	PF00018	0.719
LIG_SH3_3	355	361	PF00018	0.564
LIG_SH3_3	46	52	PF00018	0.683
LIG_SH3_3	535	541	PF00018	0.542
LIG_SH3_3	569	575	PF00018	0.712
LIG_SH3_3	576	582	PF00018	0.635
LIG_SUMO_SIM_par_1	51	57	PF11976	0.595
LIG_TRAF2_1	409	412	PF00917	0.519
LIG_TRAF2_1	528	531	PF00917	0.699
LIG_TRAF2_1	98	101	PF00917	0.726
LIG_TRFH_1	571	575	PF08558	0.602
MOD_CDK_SPK_2	293	298	PF00069	0.607
MOD_CDK_SPxxK_3	293	300	PF00069	0.668
MOD_CDK_SPxxK_3	356	363	PF00069	0.607
MOD_CK1_1	359	365	PF00069	0.724
MOD_CK2_1	213	219	PF00069	0.496
MOD_CK2_1	406	412	PF00069	0.592
MOD_CK2_1	467	473	PF00069	0.657
MOD_CK2_1	514	520	PF00069	0.716
MOD_CK2_1	70	76	PF00069	0.786
MOD_CK2_1	91	97	PF00069	0.719
MOD_Cter_Amidation	509	512	PF01082	0.672
MOD_GlcNHglycan	189	192	PF01048	0.628
MOD_GlcNHglycan	21	25	PF01048	0.806
MOD_GlcNHglycan	248	251	PF01048	0.701
MOD_GlcNHglycan	293	296	PF01048	0.770
MOD_GlcNHglycan	465	468	PF01048	0.695
MOD_GSK3_1	106	113	PF00069	0.672
MOD_GSK3_1	205	212	PF00069	0.668
MOD_GSK3_1	238	245	PF00069	0.723
MOD_GSK3_1	278	285	PF00069	0.629
MOD_GSK3_1	352	359	PF00069	0.770
MOD_GSK3_1	412	419	PF00069	0.751
MOD_GSK3_1	435	442	PF00069	0.544
MOD_GSK3_1	463	470	PF00069	0.655
MOD_GSK3_1	66	73	PF00069	0.622
MOD_GSK3_1	91	98	PF00069	0.613
MOD_N-GLC_1	435	440	PF02516	0.549
MOD_N-GLC_1	66	71	PF02516	0.670
MOD_N-GLC_2	175	177	PF02516	0.554
MOD_NEK2_1	446	451	PF00069	0.669
MOD_NEK2_1	485	490	PF00069	0.576
MOD_NEK2_1	66	71	PF00069	0.627
MOD_PIKK_1	205	211	PF00454	0.667
MOD_PIKK_1	422	428	PF00454	0.598
MOD_PK_1	278	284	PF00069	0.709
MOD_PKA_1	205	211	PF00069	0.667
MOD_PKA_1	352	358	PF00069	0.731
MOD_PKA_1	397	403	PF00069	0.684
MOD_PKA_2	106	112	PF00069	0.734
MOD_PKA_2	205	211	PF00069	0.667
MOD_PKA_2	299	305	PF00069	0.692
MOD_PKA_2	492	498	PF00069	0.628
MOD_PKA_2	67	73	PF00069	0.765
MOD_Plk_1	485	491	PF00069	0.573
MOD_Plk_2-3	83	89	PF00069	0.607
MOD_Plk_2-3	91	97	PF00069	0.611
MOD_Plk_4	106	112	PF00069	0.589
MOD_Plk_4	397	403	PF00069	0.684
MOD_Plk_4	448	454	PF00069	0.508
MOD_ProDKin_1	210	216	PF00069	0.723
MOD_ProDKin_1	293	299	PF00069	0.667
MOD_ProDKin_1	356	362	PF00069	0.717
MOD_ProDKin_1	435	441	PF00069	0.598
MOD_SUMO_rev_2	271	280	PF00179	0.685
MOD_SUMO_rev_2	314	320	PF00179	0.506
MOD_SUMO_rev_2	390	400	PF00179	0.624
MOD_SUMO_rev_2	443	452	PF00179	0.718
TRG_DiLeu_BaEn_1	316	321	PF01217	0.659
TRG_DiLeu_BaEn_3	150	156	PF01217	0.712
TRG_DiLeu_BaLyEn_6	61	66	PF01217	0.542
TRG_ENDOCYTIC_2	338	341	PF00928	0.675
TRG_ENDOCYTIC_2	496	499	PF00928	0.692
TRG_ER_diArg_1	125	127	PF00400	0.616
TRG_ER_diArg_1	297	300	PF00400	0.758
TRG_Pf-PMV_PEXEL_1	192	196	PF00026	0.473
TRG_Pf-PMV_PEXEL_1	234	238	PF00026	0.723
TRG_Pf-PMV_PEXEL_1	326	330	PF00026	0.630

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7XAV9	Leishmania donovani	84%	100%
A4HP88	Leishmania braziliensis	61%	100%
A4IDJ3	Leishmania infantum	84%	100%
Q4Q1K2	Leishmania major	82%	100%