LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ASZ6_LEIMU
TriTrypDb:
LmxM.36.2190
Length:
587

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASZ6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASZ6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 283 287 PF00656 0.707
CLV_NRD_NRD_1 126 128 PF00675 0.563
CLV_NRD_NRD_1 159 161 PF00675 0.524
CLV_NRD_NRD_1 182 184 PF00675 0.483
CLV_NRD_NRD_1 205 207 PF00675 0.719
CLV_NRD_NRD_1 304 306 PF00675 0.843
CLV_NRD_NRD_1 351 353 PF00675 0.715
CLV_NRD_NRD_1 396 398 PF00675 0.461
CLV_NRD_NRD_1 471 473 PF00675 0.656
CLV_NRD_NRD_1 492 494 PF00675 0.629
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7XAV9 Leishmania donovani 84% 100%
A4HP88 Leishmania braziliensis 61% 100%
A4IDJ3 Leishmania infantum 84% 100%
Q4Q1K2 Leishmania major 82% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS