Putative mismatch repair protein MSH8

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNA mismatch repair protein MSH6, putative

Species:

Leishmania mexicana

UniProt:

E9ASW9_LEIMU

TriTrypDb:

LmxM.36.1950

Length:

1014

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 9

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9ASW9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASW9

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	11
GO:0006259	DNA metabolic process	4	11
GO:0006281	DNA repair	5	11
GO:0006298	mismatch repair	6	11
GO:0006725	cellular aromatic compound metabolic process	3	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0006950	response to stress	2	11
GO:0006974	DNA damage response	4	11
GO:0008152	metabolic process	1	11
GO:0009987	cellular process	1	11
GO:0033554	cellular response to stress	3	11
GO:0034641	cellular nitrogen compound metabolic process	3	11
GO:0043170	macromolecule metabolic process	3	11
GO:0044237	cellular metabolic process	2	11
GO:0044238	primary metabolic process	2	11
GO:0044260	obsolete cellular macromolecule metabolic process	3	11
GO:0046483	heterocycle metabolic process	3	11
GO:0050896	response to stimulus	1	11
GO:0051716	cellular response to stimulus	2	11
GO:0071704	organic substance metabolic process	2	11
GO:0090304	nucleic acid metabolic process	4	11
GO:1901360	organic cyclic compound metabolic process	3	11
GO:0032042	mitochondrial DNA metabolic process	5	1
GO:0043504	mitochondrial DNA repair	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003676	nucleic acid binding	3	11
GO:0003677	DNA binding	4	11
GO:0003690	double-stranded DNA binding	5	11
GO:0003824	catalytic activity	1	11
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0008094	ATP-dependent activity, acting on DNA	2	11
GO:0017076	purine nucleotide binding	4	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0030983	mismatched DNA binding	6	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:0140097	catalytic activity, acting on DNA	3	11
GO:0140299	small molecule sensor activity	1	11
GO:0140612	DNA damage sensor activity	2	11
GO:0140640	catalytic activity, acting on a nucleic acid	2	11
GO:0140657	ATP-dependent activity	1	11
GO:0140664	ATP-dependent DNA damage sensor activity	3	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	192	194	PF00675	0.351
CLV_NRD_NRD_1	202	204	PF00675	0.476
CLV_NRD_NRD_1	264	266	PF00675	0.456
CLV_NRD_NRD_1	411	413	PF00675	0.312
CLV_NRD_NRD_1	608	610	PF00675	0.314
CLV_PCSK_KEX2_1	192	194	PF00082	0.359
CLV_PCSK_KEX2_1	204	206	PF00082	0.582
CLV_PCSK_KEX2_1	221	223	PF00082	0.563
CLV_PCSK_KEX2_1	264	266	PF00082	0.470
CLV_PCSK_KEX2_1	411	413	PF00082	0.218
CLV_PCSK_KEX2_1	459	461	PF00082	0.218
CLV_PCSK_KEX2_1	563	565	PF00082	0.305
CLV_PCSK_KEX2_1	608	610	PF00082	0.314
CLV_PCSK_PC1ET2_1	204	206	PF00082	0.443
CLV_PCSK_PC1ET2_1	221	223	PF00082	0.563
CLV_PCSK_PC1ET2_1	459	461	PF00082	0.218
CLV_PCSK_PC1ET2_1	563	565	PF00082	0.269
CLV_PCSK_SKI1_1	165	169	PF00082	0.435
CLV_PCSK_SKI1_1	205	209	PF00082	0.663
CLV_PCSK_SKI1_1	411	415	PF00082	0.280
CLV_PCSK_SKI1_1	527	531	PF00082	0.322
CLV_PCSK_SKI1_1	628	632	PF00082	0.295
CLV_PCSK_SKI1_1	653	657	PF00082	0.249
CLV_PCSK_SKI1_1	673	677	PF00082	0.261
CLV_PCSK_SKI1_1	771	775	PF00082	0.417
CLV_PCSK_SKI1_1	815	819	PF00082	0.221
CLV_PCSK_SKI1_1	86	90	PF00082	0.274
CLV_PCSK_SKI1_1	903	907	PF00082	0.269
DEG_APCC_DBOX_1	806	814	PF00400	0.363
DEG_ODPH_VHL_1	172	183	PF01847	0.414
DEG_SPOP_SBC_1	584	588	PF00917	0.512
DOC_CKS1_1	149	154	PF01111	0.418
DOC_CYCLIN_yClb5_NLxxxL_5	438	447	PF00134	0.469
DOC_CYCLIN_yClb5_NLxxxL_5	506	513	PF00134	0.512
DOC_CYCLIN_yCln2_LP_2	799	805	PF00134	0.469
DOC_MAPK_FxFP_2	15	18	PF00069	0.424
DOC_MAPK_gen_1	459	469	PF00069	0.469
DOC_MAPK_gen_1	506	513	PF00069	0.446
DOC_MAPK_gen_1	53	62	PF00069	0.431
DOC_MAPK_MEF2A_6	292	299	PF00069	0.366
DOC_MAPK_MEF2A_6	506	513	PF00069	0.498
DOC_MAPK_MEF2A_6	55	63	PF00069	0.449
DOC_MAPK_MEF2A_6	628	637	PF00069	0.432
DOC_MAPK_MEF2A_6	788	796	PF00069	0.445
DOC_MAPK_MEF2A_6	828	837	PF00069	0.418
DOC_MAPK_MEF2A_6	968	976	PF00069	0.431
DOC_PP2B_LxvP_1	579	582	PF13499	0.469
DOC_PP4_FxxP_1	15	18	PF00568	0.424
DOC_USP7_MATH_1	103	107	PF00917	0.431
DOC_USP7_MATH_1	199	203	PF00917	0.378
DOC_USP7_MATH_1	293	297	PF00917	0.524
DOC_USP7_MATH_1	421	425	PF00917	0.474
DOC_USP7_MATH_1	558	562	PF00917	0.424
DOC_USP7_MATH_1	574	578	PF00917	0.429
DOC_USP7_MATH_1	584	588	PF00917	0.420
DOC_USP7_MATH_1	781	785	PF00917	0.418
DOC_USP7_UBL2_3	204	208	PF12436	0.424
DOC_WW_Pin1_4	148	153	PF00397	0.443
DOC_WW_Pin1_4	243	248	PF00397	0.272
DOC_WW_Pin1_4	580	585	PF00397	0.497
DOC_WW_Pin1_4	641	646	PF00397	0.512
DOC_WW_Pin1_4	808	813	PF00397	0.512
DOC_WW_Pin1_4	903	908	PF00397	0.461
LIG_14-3-3_CanoR_1	236	245	PF00244	0.452
LIG_14-3-3_CanoR_1	264	269	PF00244	0.366
LIG_14-3-3_CanoR_1	412	418	PF00244	0.423
LIG_14-3-3_CanoR_1	420	428	PF00244	0.411
LIG_14-3-3_CanoR_1	460	470	PF00244	0.374
LIG_14-3-3_CanoR_1	517	525	PF00244	0.484
LIG_14-3-3_CanoR_1	651	660	PF00244	0.415
LIG_14-3-3_CanoR_1	700	708	PF00244	0.478
LIG_14-3-3_CanoR_1	731	740	PF00244	0.415
LIG_14-3-3_CanoR_1	860	870	PF00244	0.418
LIG_BIR_III_4	767	771	PF00653	0.243
LIG_BRCT_BRCA1_1	11	15	PF00533	0.468
LIG_BRCT_BRCA1_1	280	284	PF00533	0.490
LIG_BRCT_BRCA1_1	474	478	PF00533	0.465
LIG_BRCT_BRCA1_1	586	590	PF00533	0.419
LIG_Clathr_ClatBox_1	630	634	PF01394	0.474
LIG_CtBP_PxDLS_1	777	783	PF00389	0.418
LIG_deltaCOP1_diTrp_1	109	116	PF00928	0.418
LIG_FHA_1	29	35	PF00498	0.442
LIG_FHA_1	298	304	PF00498	0.591
LIG_FHA_1	330	336	PF00498	0.360
LIG_FHA_1	584	590	PF00498	0.495
LIG_FHA_1	592	598	PF00498	0.440
LIG_FHA_1	787	793	PF00498	0.418
LIG_FHA_1	830	836	PF00498	0.436
LIG_FHA_1	838	844	PF00498	0.461
LIG_FHA_1	912	918	PF00498	0.371
LIG_FHA_2	152	158	PF00498	0.418
LIG_FHA_2	207	213	PF00498	0.646
LIG_FHA_2	269	275	PF00498	0.444
LIG_FHA_2	277	283	PF00498	0.480
LIG_FHA_2	325	331	PF00498	0.368
LIG_FHA_2	339	345	PF00498	0.403
LIG_FHA_2	446	452	PF00498	0.344
LIG_FHA_2	554	560	PF00498	0.469
LIG_FHA_2	732	738	PF00498	0.478
LIG_FHA_2	804	810	PF00498	0.512
LIG_LIR_Apic_2	12	18	PF02991	0.443
LIG_LIR_Gen_1	109	116	PF02991	0.420
LIG_LIR_Gen_1	310	319	PF02991	0.377
LIG_LIR_Gen_1	439	447	PF02991	0.344
LIG_LIR_Gen_1	468	478	PF02991	0.438
LIG_LIR_Gen_1	54	63	PF02991	0.449
LIG_LIR_Gen_1	73	79	PF02991	0.449
LIG_LIR_Gen_1	814	825	PF02991	0.426
LIG_LIR_Gen_1	831	841	PF02991	0.418
LIG_LIR_Gen_1	891	902	PF02991	0.418
LIG_LIR_Nem_3	109	113	PF02991	0.420
LIG_LIR_Nem_3	14	20	PF02991	0.352
LIG_LIR_Nem_3	310	316	PF02991	0.411
LIG_LIR_Nem_3	439	444	PF02991	0.408
LIG_LIR_Nem_3	46	52	PF02991	0.418
LIG_LIR_Nem_3	468	473	PF02991	0.425
LIG_LIR_Nem_3	475	481	PF02991	0.429
LIG_LIR_Nem_3	54	60	PF02991	0.418
LIG_LIR_Nem_3	696	701	PF02991	0.477
LIG_LIR_Nem_3	726	732	PF02991	0.392
LIG_LIR_Nem_3	73	77	PF02991	0.449
LIG_LIR_Nem_3	814	820	PF02991	0.427
LIG_LIR_Nem_3	831	837	PF02991	0.418
LIG_LIR_Nem_3	891	897	PF02991	0.418
LIG_LYPXL_yS_3	17	20	PF13949	0.461
LIG_LYPXL_yS_3	729	732	PF13949	0.396
LIG_NRBOX	237	243	PF00104	0.395
LIG_NRBOX	547	553	PF00104	0.512
LIG_NRBOX	791	797	PF00104	0.386
LIG_PCNA_yPIPBox_3	562	571	PF02747	0.344
LIG_PDZ_Class_2	1009	1014	PF00595	0.505
LIG_Pex14_1	110	114	PF04695	0.418
LIG_Pex14_1	525	529	PF04695	0.512
LIG_Pex14_2	15	19	PF04695	0.434
LIG_Pex14_2	698	702	PF04695	0.527
LIG_PTAP_UEV_1	24	29	PF05743	0.520
LIG_PTB_Apo_2	77	84	PF02174	0.501
LIG_PTB_Apo_2	951	958	PF02174	0.436
LIG_Rb_pABgroove_1	563	571	PF01858	0.474
LIG_REV1ctd_RIR_1	527	536	PF16727	0.348
LIG_REV1ctd_RIR_1	60	69	PF16727	0.431
LIG_SH2_CRK	196	200	PF00017	0.345
LIG_SH2_CRK	227	231	PF00017	0.381
LIG_SH2_CRK	441	445	PF00017	0.469
LIG_SH2_CRK	57	61	PF00017	0.469
LIG_SH2_CRK	74	78	PF00017	0.389
LIG_SH2_CRK	872	876	PF00017	0.489
LIG_SH2_CRK	894	898	PF00017	0.418
LIG_SH2_CRK	959	963	PF00017	0.431
LIG_SH2_PTP2	498	501	PF00017	0.512
LIG_SH2_PTP2	834	837	PF00017	0.431
LIG_SH2_SRC	38	41	PF00017	0.433
LIG_SH2_SRC	498	501	PF00017	0.512
LIG_SH2_STAP1	331	335	PF00017	0.405
LIG_SH2_STAP1	365	369	PF00017	0.509
LIG_SH2_STAP1	72	76	PF00017	0.429
LIG_SH2_STAT5	312	315	PF00017	0.340
LIG_SH2_STAT5	331	334	PF00017	0.400
LIG_SH2_STAT5	38	41	PF00017	0.562
LIG_SH2_STAT5	498	501	PF00017	0.525
LIG_SH2_STAT5	660	663	PF00017	0.449
LIG_SH2_STAT5	710	713	PF00017	0.448
LIG_SH2_STAT5	834	837	PF00017	0.451
LIG_SH3_3	146	152	PF00018	0.432
LIG_SH3_3	22	28	PF00018	0.399
LIG_SH3_3	724	730	PF00018	0.449
LIG_SH3_3	880	886	PF00018	0.449
LIG_SUMO_SIM_anti_2	145	151	PF11976	0.431
LIG_SUMO_SIM_anti_2	381	387	PF11976	0.418
LIG_SUMO_SIM_anti_2	739	744	PF11976	0.347
LIG_SUMO_SIM_anti_2	973	978	PF11976	0.431
LIG_SUMO_SIM_par_1	145	151	PF11976	0.431
LIG_SUMO_SIM_par_1	471	477	PF11976	0.424
LIG_SUMO_SIM_par_1	771	776	PF11976	0.334
LIG_SUMO_SIM_par_1	885	892	PF11976	0.418
LIG_TRAF2_1	573	576	PF00917	0.512
LIG_TYR_ITIM	727	732	PF00017	0.444
LIG_TYR_ITIM	870	875	PF00017	0.489
LIG_UBA3_1	241	248	PF00899	0.391
LIG_UBA3_1	748	756	PF00899	0.420
LIG_WRC_WIRS_1	312	317	PF05994	0.370
MOD_CDK_SPK_2	243	248	PF00069	0.272
MOD_CDK_SPxxK_3	808	815	PF00069	0.512
MOD_CK1_1	159	165	PF00069	0.425
MOD_CK1_1	216	222	PF00069	0.689
MOD_CK1_1	298	304	PF00069	0.555
MOD_CK1_1	30	36	PF00069	0.445
MOD_CK1_1	311	317	PF00069	0.479
MOD_CK1_1	326	332	PF00069	0.503
MOD_CK1_1	348	354	PF00069	0.548
MOD_CK1_1	357	363	PF00069	0.431
MOD_CK1_1	422	428	PF00069	0.457
MOD_CK1_1	461	467	PF00069	0.426
MOD_CK1_1	468	474	PF00069	0.446
MOD_CK1_1	483	489	PF00069	0.464
MOD_CK1_1	583	589	PF00069	0.491
MOD_CK1_1	654	660	PF00069	0.346
MOD_CK1_1	689	695	PF00069	0.569
MOD_CK1_1	848	854	PF00069	0.543
MOD_CK1_1	950	956	PF00069	0.478
MOD_CK1_1	996	1002	PF00069	0.553
MOD_CK2_1	103	109	PF00069	0.418
MOD_CK2_1	127	133	PF00069	0.436
MOD_CK2_1	243	249	PF00069	0.269
MOD_CK2_1	268	274	PF00069	0.505
MOD_CK2_1	276	282	PF00069	0.531
MOD_CK2_1	324	330	PF00069	0.374
MOD_CK2_1	338	344	PF00069	0.428
MOD_CK2_1	378	384	PF00069	0.431
MOD_CK2_1	394	400	PF00069	0.431
MOD_CK2_1	445	451	PF00069	0.374
MOD_CK2_1	553	559	PF00069	0.469
MOD_CK2_1	660	666	PF00069	0.484
MOD_CK2_1	668	674	PF00069	0.509
MOD_CK2_1	731	737	PF00069	0.467
MOD_CK2_1	803	809	PF00069	0.482
MOD_Cter_Amidation	409	412	PF01082	0.218
MOD_GlcNHglycan	238	241	PF01048	0.452
MOD_GlcNHglycan	335	338	PF01048	0.520
MOD_GlcNHglycan	356	359	PF01048	0.539
MOD_GlcNHglycan	421	424	PF01048	0.249
MOD_GlcNHglycan	519	522	PF01048	0.298
MOD_GlcNHglycan	575	579	PF01048	0.232
MOD_GlcNHglycan	653	656	PF01048	0.155
MOD_GlcNHglycan	702	705	PF01048	0.269
MOD_GlcNHglycan	845	848	PF01048	0.320
MOD_GSK3_1	129	136	PF00069	0.395
MOD_GSK3_1	206	213	PF00069	0.688
MOD_GSK3_1	226	233	PF00069	0.387
MOD_GSK3_1	23	30	PF00069	0.521
MOD_GSK3_1	252	259	PF00069	0.476
MOD_GSK3_1	264	271	PF00069	0.572
MOD_GSK3_1	278	285	PF00069	0.474
MOD_GSK3_1	293	300	PF00069	0.489
MOD_GSK3_1	307	314	PF00069	0.346
MOD_GSK3_1	326	333	PF00069	0.371
MOD_GSK3_1	338	345	PF00069	0.478
MOD_GSK3_1	354	361	PF00069	0.531
MOD_GSK3_1	390	397	PF00069	0.468
MOD_GSK3_1	461	468	PF00069	0.474
MOD_GSK3_1	580	587	PF00069	0.426
MOD_GSK3_1	682	689	PF00069	0.502
MOD_GSK3_1	702	709	PF00069	0.398
MOD_GSK3_1	782	789	PF00069	0.418
MOD_GSK3_1	885	892	PF00069	0.501
MOD_GSK3_1	9	16	PF00069	0.549
MOD_GSK3_1	901	908	PF00069	0.381
MOD_GSK3_1	925	932	PF00069	0.364
MOD_GSK3_1	989	996	PF00069	0.489
MOD_N-GLC_1	231	236	PF02516	0.308
MOD_N-GLC_1	490	495	PF02516	0.253
MOD_N-GLC_1	761	766	PF02516	0.287
MOD_N-GLC_1	939	944	PF02516	0.265
MOD_N-GLC_2	399	401	PF02516	0.231
MOD_N-GLC_2	403	405	PF02516	0.205
MOD_NEK2_1	168	173	PF00069	0.350
MOD_NEK2_1	230	235	PF00069	0.420
MOD_NEK2_1	297	302	PF00069	0.639
MOD_NEK2_1	3	8	PF00069	0.493
MOD_NEK2_1	375	380	PF00069	0.338
MOD_NEK2_1	413	418	PF00069	0.445
MOD_NEK2_1	443	448	PF00069	0.485
MOD_NEK2_1	469	474	PF00069	0.527
MOD_NEK2_1	668	673	PF00069	0.572
MOD_NEK2_1	702	707	PF00069	0.509
MOD_NEK2_1	773	778	PF00069	0.279
MOD_NEK2_1	786	791	PF00069	0.369
MOD_NEK2_1	89	94	PF00069	0.477
MOD_NEK2_2	585	590	PF00069	0.447
MOD_NEK2_2	829	834	PF00069	0.431
MOD_NEK2_2	871	876	PF00069	0.474
MOD_OFUCOSY	946	951	PF10250	0.216
MOD_PIKK_1	3	9	PF00454	0.571
MOD_PIKK_1	490	496	PF00454	0.454
MOD_PKA_1	264	270	PF00069	0.367
MOD_PKA_2	264	270	PF00069	0.311
MOD_PKA_2	403	409	PF00069	0.472
MOD_PKA_2	419	425	PF00069	0.353
MOD_PKA_2	461	467	PF00069	0.371
MOD_PKA_2	483	489	PF00069	0.491
MOD_PKA_2	859	865	PF00069	0.418
MOD_PKA_2	996	1002	PF00069	0.553
MOD_Plk_1	103	109	PF00069	0.418
MOD_Plk_1	231	237	PF00069	0.353
MOD_Plk_1	348	354	PF00069	0.577
MOD_Plk_1	375	381	PF00069	0.284
MOD_Plk_1	673	679	PF00069	0.469
MOD_Plk_1	761	767	PF00069	0.401
MOD_Plk_2-3	282	288	PF00069	0.394
MOD_Plk_2-3	394	400	PF00069	0.512
MOD_Plk_4	156	162	PF00069	0.585
MOD_Plk_4	298	304	PF00069	0.656
MOD_Plk_4	308	314	PF00069	0.428
MOD_Plk_4	358	364	PF00069	0.425
MOD_Plk_4	465	471	PF00069	0.495
MOD_Plk_4	585	591	PF00069	0.410
MOD_Plk_4	682	688	PF00069	0.523
MOD_Plk_4	706	712	PF00069	0.457
MOD_Plk_4	782	788	PF00069	0.418
MOD_Plk_4	829	835	PF00069	0.418
MOD_Plk_4	885	891	PF00069	0.499
MOD_Plk_4	980	986	PF00069	0.474
MOD_ProDKin_1	148	154	PF00069	0.443
MOD_ProDKin_1	243	249	PF00069	0.269
MOD_ProDKin_1	580	586	PF00069	0.497
MOD_ProDKin_1	641	647	PF00069	0.512
MOD_ProDKin_1	808	814	PF00069	0.512
MOD_ProDKin_1	903	909	PF00069	0.461
MOD_SUMO_for_1	220	223	PF00179	0.581
MOD_SUMO_for_1	926	929	PF00179	0.512
MOD_SUMO_for_1	990	993	PF00179	0.469
MOD_SUMO_rev_2	202	209	PF00179	0.510
MOD_SUMO_rev_2	46	54	PF00179	0.431
TRG_DiLeu_BaEn_1	575	580	PF01217	0.514
TRG_DiLeu_BaEn_1	769	774	PF01217	0.443
TRG_DiLeu_BaLyEn_6	748	753	PF01217	0.444
TRG_ENDOCYTIC_2	17	20	PF00928	0.329
TRG_ENDOCYTIC_2	227	230	PF00928	0.386
TRG_ENDOCYTIC_2	312	315	PF00928	0.398
TRG_ENDOCYTIC_2	441	444	PF00928	0.469
TRG_ENDOCYTIC_2	49	52	PF00928	0.431
TRG_ENDOCYTIC_2	57	60	PF00928	0.431
TRG_ENDOCYTIC_2	729	732	PF00928	0.396
TRG_ENDOCYTIC_2	74	77	PF00928	0.385
TRG_ENDOCYTIC_2	834	837	PF00928	0.431
TRG_ENDOCYTIC_2	872	875	PF00928	0.489
TRG_ENDOCYTIC_2	894	897	PF00928	0.418
TRG_ENDOCYTIC_2	921	924	PF00928	0.418
TRG_ENDOCYTIC_2	959	962	PF00928	0.431
TRG_ER_diArg_1	192	194	PF00400	0.359
TRG_ER_diArg_1	411	413	PF00400	0.512
TRG_ER_diArg_1	607	609	PF00400	0.514
TRG_NES_CRM1_1	307	321	PF08389	0.461
TRG_NES_CRM1_1	465	479	PF08389	0.469
TRG_Pf-PMV_PEXEL_1	144	148	PF00026	0.218
TRG_Pf-PMV_PEXEL_1	609	613	PF00026	0.285

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6K5	Leptomonas seymouri	66%	98%
A0A0S4IMQ7	Bodo saltans	42%	100%
A0A3Q8IK49	Leishmania donovani	92%	100%
A0A3R7LRN7	Trypanosoma rangeli	47%	100%
A0L7L5	Magnetococcus marinus (strain ATCC BAA-1437 / JCM 17883 / MC-1)	28%	100%
A0Q809	Francisella tularensis subsp. novicida (strain U112)	23%	100%
A3DDI3	Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372)	24%	100%
A3N2Q0	Actinobacillus pleuropneumoniae serotype 5b (strain L20)	26%	100%
A3PNR5	Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9)	26%	100%
A4HP61	Leishmania braziliensis	85%	100%
A4IDG7	Leishmania infantum	92%	100%
A4IXL2	Francisella tularensis subsp. tularensis (strain WY96-3418)	23%	100%
A4R0R0	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	27%	88%
A4WVX8	Cereibacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)	26%	100%
A5DEV6	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	25%	100%
A5VN83	Brucella ovis (strain ATCC 25840 / 63/290 / NCTC 10512)	26%	100%
A6LG92	Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)	24%	100%
A6ZTR3	Saccharomyces cerevisiae (strain YJM789)	23%	100%
A7MTT8	Vibrio campbellii (strain ATCC BAA-1116)	24%	100%
A7N9Y6	Francisella tularensis subsp. holarctica (strain FTNF002-00 / FTA)	23%	100%
A8GMX2	Rickettsia akari (strain Hartford)	22%	100%
A8I275	Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 / LMG 6465 / NBRC 14845 / NCIMB 13405 / ORS 571)	27%	100%
A9ILT1	Bartonella tribocorum (strain CIP 105476 / IBS 506)	25%	100%
A9KG24	Coxiella burnetii (strain Dugway 5J108-111)	25%	100%
A9M792	Brucella canis (strain ATCC 23365 / NCTC 10854)	26%	100%
A9NCN3	Coxiella burnetii (strain RSA 331 / Henzerling II)	25%	100%
A9WFZ9	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)	27%	100%
B0CIQ5	Brucella suis (strain ATCC 23445 / NCTC 10510)	26%	100%
B0S1C1	Finegoldia magna (strain ATCC 29328 / DSM 20472 / WAL 2508)	24%	100%
B0TX99	Francisella philomiragia subsp. philomiragia (strain ATCC 25017 / FSC 153 / O#319-036)	22%	100%
B2KB17	Elusimicrobium minutum (strain Pei191)	24%	100%
B2SEQ6	Francisella tularensis subsp. mediasiatica (strain FSC147)	23%	100%
B3EP11	Chlorobium phaeobacteroides (strain BS1)	26%	100%
B3QPY5	Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)	26%	100%
B5EA63	Citrifermentans bemidjiense (strain ATCC BAA-1014 / DSM 16622 / JCM 12645 / Bem)	24%	100%
B9LB04	Chloroflexus aurantiacus (strain ATCC 29364 / DSM 637 / Y-400-fl)	27%	100%
C4K6P7	Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)	25%	100%
D0A350	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	100%
E1BYJ2	Gallus gallus	27%	76%
O04716	Arabidopsis thaliana	29%	77%
O74502	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	28%	81%
P25336	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	100%
P25846	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	100%
P26359	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	24%	100%
P43246	Homo sapiens	23%	100%
P43247	Mus musculus	23%	100%
P52701	Homo sapiens	27%	75%
P61670	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)	26%	100%
Q03834	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	82%
Q0BNM7	Francisella tularensis subsp. holarctica (strain OSU18)	23%	100%
Q0STR4	Clostridium perfringens (strain SM101 / Type A)	25%	100%
Q0TRD6	Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A)	24%	100%
Q14GB1	Francisella tularensis subsp. tularensis (strain FSC 198)	23%	100%
Q16D05	Roseobacter denitrificans (strain ATCC 33942 / OCh 114)	25%	100%
Q1QE46	Psychrobacter cryohalolentis (strain ATCC BAA-1226 / DSM 17306 / VKM B-2378 / K5)	27%	98%
Q1QQJ4	Nitrobacter hamburgensis (strain DSM 10229 / NCIMB 13809 / X14)	26%	100%
Q1QZX5	Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)	25%	100%
Q2A5B5	Francisella tularensis subsp. holarctica (strain LVS)	23%	100%
Q2YB94	Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71)	26%	100%
Q2YNZ0	Brucella abortus (strain 2308)	26%	100%
Q30ZX3	Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)	26%	100%
Q3IYI5	Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.)	26%	100%
Q3MHE4	Bos taurus	23%	100%
Q4Q1M8	Leishmania major	93%	100%
Q57FM9	Brucella abortus biovar 1 (strain 9-941)	26%	100%
Q5NEV8	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	23%	100%
Q6G542	Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1)	25%	100%
Q6MBV4	Protochlamydia amoebophila (strain UWE25)	24%	100%
Q7V9M5	Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)	23%	100%
Q7VY01	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	26%	100%
Q7W880	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	26%	100%
Q7WLT5	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	26%	100%
Q83CQ2	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	25%	100%
Q8G310	Brucella suis biovar 1 (strain 1330)	26%	100%
Q8KCC0	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	26%	100%
Q8UIF2	Agrobacterium fabrum (strain C58 / ATCC 33970)	26%	100%
Q8XL87	Clostridium perfringens (strain 13 / Type A)	25%	100%
Q8YES6	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	26%	100%
Q98C21	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	25%	100%
V5DCH4	Trypanosoma cruzi	49%	100%