MORN repeat-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

MORN repeat, putative

Species:

Leishmania mexicana

UniProt:

E9ASV3_LEIMU

TriTrypDb:

LmxM.36.1810

Length:

938

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005930	axoneme	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9ASV3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASV3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	231	235	PF00656	0.462
CLV_C14_Caspase3-7	254	258	PF00656	0.520
CLV_C14_Caspase3-7	289	293	PF00656	0.517
CLV_C14_Caspase3-7	501	505	PF00656	0.335
CLV_C14_Caspase3-7	600	604	PF00656	0.409
CLV_C14_Caspase3-7	707	711	PF00656	0.234
CLV_C14_Caspase3-7	775	779	PF00656	0.453
CLV_C14_Caspase3-7	811	815	PF00656	0.452
CLV_C14_Caspase3-7	881	885	PF00656	0.393
CLV_C14_Caspase3-7	920	924	PF00656	0.335
CLV_NRD_NRD_1	459	461	PF00675	0.335
CLV_NRD_NRD_1	467	469	PF00675	0.335
CLV_NRD_NRD_1	506	508	PF00675	0.335
CLV_NRD_NRD_1	648	650	PF00675	0.214
CLV_NRD_NRD_1	732	734	PF00675	0.453
CLV_NRD_NRD_1	823	825	PF00675	0.638
CLV_PCSK_KEX2_1	459	461	PF00082	0.335
CLV_PCSK_KEX2_1	467	469	PF00082	0.335
CLV_PCSK_KEX2_1	506	508	PF00082	0.335
CLV_PCSK_KEX2_1	648	650	PF00082	0.335
CLV_PCSK_KEX2_1	732	734	PF00082	0.453
CLV_PCSK_KEX2_1	823	825	PF00082	0.638
CLV_PCSK_SKI1_1	155	159	PF00082	0.683
CLV_PCSK_SKI1_1	7	11	PF00082	0.597
CLV_PCSK_SKI1_1	74	78	PF00082	0.467
CLV_PCSK_SKI1_1	744	748	PF00082	0.285
DEG_APCC_DBOX_1	13	21	PF00400	0.695
DEG_SCF_FBW7_1	20	26	PF00400	0.550
DEG_SPOP_SBC_1	8	12	PF00917	0.721
DOC_ANK_TNKS_1	489	496	PF00023	0.506
DOC_CDC14_PxL_1	191	199	PF14671	0.650
DOC_CKS1_1	20	25	PF01111	0.548
DOC_CKS1_1	379	384	PF01111	0.493
DOC_CYCLIN_yCln2_LP_2	56	62	PF00134	0.480
DOC_MAPK_MEF2A_6	114	122	PF00069	0.384
DOC_MAPK_MEF2A_6	130	139	PF00069	0.410
DOC_PP1_RVXF_1	325	331	PF00149	0.563
DOC_PP2B_LxvP_1	175	178	PF13499	0.500
DOC_USP7_MATH_1	219	223	PF00917	0.681
DOC_USP7_MATH_1	23	27	PF00917	0.605
DOC_USP7_MATH_1	663	667	PF00917	0.664
DOC_USP7_MATH_1	671	675	PF00917	0.494
DOC_USP7_MATH_1	8	12	PF00917	0.750
DOC_USP7_MATH_1	815	819	PF00917	0.539
DOC_USP7_MATH_1	827	831	PF00917	0.485
DOC_USP7_MATH_1	898	902	PF00917	0.552
DOC_USP7_MATH_2	244	250	PF00917	0.661
DOC_USP7_UBL2_3	255	259	PF12436	0.512
DOC_WW_Pin1_4	19	24	PF00397	0.650
DOC_WW_Pin1_4	279	284	PF00397	0.529
DOC_WW_Pin1_4	318	323	PF00397	0.583
DOC_WW_Pin1_4	32	37	PF00397	0.785
DOC_WW_Pin1_4	362	367	PF00397	0.742
DOC_WW_Pin1_4	378	383	PF00397	0.579
DOC_WW_Pin1_4	489	494	PF00397	0.576
DOC_WW_Pin1_4	94	99	PF00397	0.528
LIG_14-3-3_CanoR_1	138	147	PF00244	0.538
LIG_14-3-3_CanoR_1	301	310	PF00244	0.553
LIG_14-3-3_CanoR_1	692	700	PF00244	0.453
LIG_14-3-3_CanoR_1	7	17	PF00244	0.727
LIG_14-3-3_CanoR_1	744	749	PF00244	0.291
LIG_14-3-3_CanoR_1	869	878	PF00244	0.453
LIG_Actin_WH2_2	773	790	PF00022	0.306
LIG_BRCT_BRCA1_1	140	144	PF00533	0.475
LIG_BRCT_BRCA1_1	33	37	PF00533	0.800
LIG_Clathr_ClatBox_2	309	314	PF01394	0.577
LIG_CtBP_PxDLS_1	322	326	PF00389	0.563
LIG_deltaCOP1_diTrp_1	470	478	PF00928	0.335
LIG_FHA_1	1	7	PF00498	0.588
LIG_FHA_1	373	379	PF00498	0.638
LIG_FHA_1	51	57	PF00498	0.532
LIG_FHA_1	741	747	PF00498	0.468
LIG_FHA_1	8	14	PF00498	0.546
LIG_FHA_1	805	811	PF00498	0.617
LIG_FHA_2	252	258	PF00498	0.626
LIG_FHA_2	27	33	PF00498	0.650
LIG_FHA_2	319	325	PF00498	0.565
LIG_FHA_2	387	393	PF00498	0.584
LIG_FHA_2	558	564	PF00498	0.456
LIG_FHA_2	692	698	PF00498	0.453
LIG_FHA_2	815	821	PF00498	0.430
LIG_FHA_2	918	924	PF00498	0.335
LIG_Integrin_RGD_1	229	231	PF01839	0.453
LIG_LIR_Apic_2	304	310	PF02991	0.580
LIG_LIR_Apic_2	312	317	PF02991	0.588
LIG_LIR_Apic_2	603	609	PF02991	0.453
LIG_LIR_Apic_2	80	86	PF02991	0.539
LIG_LIR_Nem_3	271	277	PF02991	0.587
LIG_LIR_Nem_3	415	420	PF02991	0.644
LIG_LIR_Nem_3	461	466	PF02991	0.300
LIG_LIR_Nem_3	50	54	PF02991	0.465
LIG_LIR_Nem_3	542	547	PF02991	0.415
LIG_LIR_Nem_3	747	751	PF02991	0.433
LIG_MLH1_MIPbox_1	140	144	PF16413	0.475
LIG_PDZ_Class_2	933	938	PF00595	0.447
LIG_Pex14_2	143	147	PF04695	0.574
LIG_Pex14_2	330	334	PF04695	0.611
LIG_Pex14_2	78	82	PF04695	0.514
LIG_Pex14_2	927	931	PF04695	0.416
LIG_PTB_Apo_2	930	937	PF02174	0.479
LIG_PTB_Phospho_1	930	936	PF10480	0.480
LIG_SH2_CRK	463	467	PF00017	0.278
LIG_SH2_NCK_1	241	245	PF00017	0.604
LIG_SH2_PTP2	606	609	PF00017	0.335
LIG_SH2_SRC	538	541	PF00017	0.332
LIG_SH2_SRC	812	815	PF00017	0.478
LIG_SH2_STAT3	124	127	PF00017	0.385
LIG_SH2_STAT3	474	477	PF00017	0.335
LIG_SH2_STAT3	652	655	PF00017	0.389
LIG_SH2_STAT5	124	127	PF00017	0.470
LIG_SH2_STAT5	224	227	PF00017	0.354
LIG_SH2_STAT5	451	454	PF00017	0.335
LIG_SH2_STAT5	51	54	PF00017	0.473
LIG_SH2_STAT5	606	609	PF00017	0.335
LIG_SH2_STAT5	640	643	PF00017	0.335
LIG_SH2_STAT5	772	775	PF00017	0.453
LIG_SH2_STAT5	812	815	PF00017	0.478
LIG_SH2_STAT5	832	835	PF00017	0.183
LIG_SH3_1	30	36	PF00018	0.585
LIG_SH3_1	418	424	PF00018	0.594
LIG_SH3_3	102	108	PF00018	0.513
LIG_SH3_3	186	192	PF00018	0.658
LIG_SH3_3	30	36	PF00018	0.760
LIG_SH3_3	360	366	PF00018	0.725
LIG_SH3_3	373	379	PF00018	0.604
LIG_SH3_3	380	386	PF00018	0.649
LIG_SH3_3	418	424	PF00018	0.540
LIG_SH3_3	654	660	PF00018	0.585
LIG_SH3_CIN85_PxpxPR_1	283	288	PF14604	0.523
LIG_SUMO_SIM_par_1	52	57	PF11976	0.518
LIG_TRAF2_1	243	246	PF00917	0.657
LIG_TRAF2_1	435	438	PF00917	0.214
LIG_TYR_ITIM	49	54	PF00017	0.472
LIG_TYR_ITIM	746	751	PF00017	0.473
MOD_CK1_1	12	18	PF00069	0.663
MOD_CK1_1	128	134	PF00069	0.622
MOD_CK1_1	249	255	PF00069	0.796
MOD_CK1_1	26	32	PF00069	0.761
MOD_CK1_1	312	318	PF00069	0.600
MOD_CK1_1	50	56	PF00069	0.646
MOD_CK1_1	638	644	PF00069	0.335
MOD_CK1_1	759	765	PF00069	0.494
MOD_CK1_1	874	880	PF00069	0.398
MOD_CK2_1	386	392	PF00069	0.612
MOD_CK2_1	719	725	PF00069	0.506
MOD_CK2_1	764	770	PF00069	0.344
MOD_CK2_1	850	856	PF00069	0.335
MOD_CMANNOS	311	314	PF00535	0.584
MOD_Cter_Amidation	457	460	PF01082	0.335
MOD_Cter_Amidation	504	507	PF01082	0.335
MOD_GlcNHglycan	126	130	PF01048	0.654
MOD_GlcNHglycan	179	182	PF01048	0.706
MOD_GlcNHglycan	208	211	PF01048	0.779
MOD_GlcNHglycan	288	291	PF01048	0.606
MOD_GlcNHglycan	311	314	PF01048	0.597
MOD_GlcNHglycan	509	512	PF01048	0.321
MOD_GlcNHglycan	632	635	PF01048	0.455
MOD_GlcNHglycan	649	652	PF01048	0.335
MOD_GlcNHglycan	665	668	PF01048	0.511
MOD_GlcNHglycan	687	690	PF01048	0.335
MOD_GlcNHglycan	740	743	PF01048	0.335
MOD_GlcNHglycan	816	820	PF01048	0.521
MOD_GlcNHglycan	873	876	PF01048	0.335
MOD_GSK3_1	147	154	PF00069	0.637
MOD_GSK3_1	164	171	PF00069	0.585
MOD_GSK3_1	19	26	PF00069	0.656
MOD_GSK3_1	249	256	PF00069	0.571
MOD_GSK3_1	312	319	PF00069	0.599
MOD_GSK3_1	333	340	PF00069	0.606
MOD_GSK3_1	344	351	PF00069	0.758
MOD_GSK3_1	364	371	PF00069	0.516
MOD_GSK3_1	50	57	PF00069	0.493
MOD_GSK3_1	507	514	PF00069	0.389
MOD_GSK3_1	557	564	PF00069	0.462
MOD_GSK3_1	715	722	PF00069	0.579
MOD_GSK3_1	740	747	PF00069	0.413
MOD_GSK3_1	755	762	PF00069	0.450
MOD_GSK3_1	8	15	PF00069	0.639
MOD_LATS_1	754	760	PF00433	0.517
MOD_N-GLC_1	18	23	PF02516	0.693
MOD_N-GLC_1	764	769	PF02516	0.348
MOD_NEK2_1	1	6	PF00069	0.696
MOD_NEK2_1	125	130	PF00069	0.465
MOD_NEK2_1	18	23	PF00069	0.606
MOD_NEK2_1	208	213	PF00069	0.718
MOD_NEK2_1	248	253	PF00069	0.735
MOD_NEK2_1	261	266	PF00069	0.518
MOD_NEK2_1	334	339	PF00069	0.612
MOD_NEK2_1	372	377	PF00069	0.699
MOD_NEK2_1	447	452	PF00069	0.397
MOD_NEK2_1	77	82	PF00069	0.445
MOD_NEK2_2	219	224	PF00069	0.711
MOD_NEK2_2	783	788	PF00069	0.306
MOD_NEK2_2	898	903	PF00069	0.448
MOD_NEK2_2	9	14	PF00069	0.517
MOD_NEK2_2	922	927	PF00069	0.335
MOD_OFUCOSY	75	81	PF10250	0.445
MOD_PIKK_1	23	29	PF00454	0.669
MOD_PIKK_1	246	252	PF00454	0.663
MOD_PIKK_1	54	60	PF00454	0.606
MOD_PIKK_1	561	567	PF00454	0.572
MOD_PIKK_1	843	849	PF00454	0.335
MOD_PK_1	756	762	PF00069	0.504
MOD_PK_1	850	856	PF00069	0.335
MOD_PKA_2	206	212	PF00069	0.659
MOD_PKA_2	647	653	PF00069	0.214
MOD_PKA_2	671	677	PF00069	0.469
MOD_PKA_2	691	697	PF00069	0.326
MOD_PKA_2	715	721	PF00069	0.522
MOD_PKA_2	755	761	PF00069	0.572
MOD_PKA_2	868	874	PF00069	0.335
MOD_Plk_1	261	267	PF00069	0.688
MOD_Plk_1	368	374	PF00069	0.709
MOD_Plk_1	447	453	PF00069	0.414
MOD_Plk_1	764	770	PF00069	0.344
MOD_Plk_2-3	540	546	PF00069	0.425
MOD_Plk_4	219	225	PF00069	0.615
MOD_Plk_4	47	53	PF00069	0.614
MOD_Plk_4	602	608	PF00069	0.453
MOD_Plk_4	635	641	PF00069	0.426
MOD_Plk_4	719	725	PF00069	0.452
MOD_Plk_4	772	778	PF00069	0.453
MOD_Plk_4	850	856	PF00069	0.335
MOD_Plk_4	898	904	PF00069	0.519
MOD_Plk_4	922	928	PF00069	0.335
MOD_ProDKin_1	19	25	PF00069	0.650
MOD_ProDKin_1	279	285	PF00069	0.530
MOD_ProDKin_1	318	324	PF00069	0.575
MOD_ProDKin_1	32	38	PF00069	0.783
MOD_ProDKin_1	362	368	PF00069	0.744
MOD_ProDKin_1	378	384	PF00069	0.580
MOD_ProDKin_1	489	495	PF00069	0.573
MOD_ProDKin_1	94	100	PF00069	0.529
MOD_SUMO_rev_2	256	261	PF00179	0.512
MOD_SUMO_rev_2	34	43	PF00179	0.654
TRG_DiLeu_BaEn_2	460	466	PF01217	0.389
TRG_DiLeu_BaLyEn_6	91	96	PF01217	0.528
TRG_ENDOCYTIC_2	444	447	PF00928	0.314
TRG_ENDOCYTIC_2	463	466	PF00928	0.466
TRG_ENDOCYTIC_2	51	54	PF00928	0.473
TRG_ENDOCYTIC_2	544	547	PF00928	0.421
TRG_ENDOCYTIC_2	748	751	PF00928	0.429
TRG_ER_diArg_1	13	16	PF00400	0.593
TRG_ER_diArg_1	466	468	PF00400	0.335
TRG_ER_diArg_1	532	535	PF00400	0.399
TRG_ER_diArg_1	822	824	PF00400	0.639

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I572	Leptomonas seymouri	57%	98%
A0A3S7XAW7	Leishmania donovani	88%	100%
A4HP45	Leishmania braziliensis	77%	100%
A4IDF2	Leishmania infantum	88%	100%
Q4Q1P3	Leishmania major	89%	100%