Tetratricopeptide repeat-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

TPR repeat, putative

Species:

Leishmania mexicana

UniProt:

E9ASV0_LEIMU

TriTrypDb:

LmxM.36.1780

Length:

743

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASV0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASV0

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	265	269	PF00656	0.523
CLV_C14_Caspase3-7	392	396	PF00656	0.626
CLV_C14_Caspase3-7	495	499	PF00656	0.507
CLV_C14_Caspase3-7	546	550	PF00656	0.568
CLV_MEL_PAP_1	708	714	PF00089	0.479
CLV_NRD_NRD_1	101	103	PF00675	0.559
CLV_NRD_NRD_1	344	346	PF00675	0.535
CLV_NRD_NRD_1	383	385	PF00675	0.692
CLV_NRD_NRD_1	443	445	PF00675	0.486
CLV_NRD_NRD_1	644	646	PF00675	0.723

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6L1	Leptomonas seymouri	53%	89%
A0A1X0P7U7	Trypanosomatidae	34%	100%
A0A3R7KED7	Trypanosoma rangeli	33%	100%
A0A3S7XAR1	Leishmania donovani	86%	100%
A4HP42	Leishmania braziliensis	70%	100%
A4IDE9	Leishmania infantum	86%	100%
D0A326	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	100%
Q4Q1P6	Leishmania major	86%	100%
V5BPH3	Trypanosoma cruzi	32%	100%

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