LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AST0_LEIMU
TriTrypDb:
LmxM.36.1595
Length:
123

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AST0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AST0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 21 25 PF00656 0.672
CLV_NRD_NRD_1 101 103 PF00675 0.644
CLV_NRD_NRD_1 2 4 PF00675 0.748
CLV_PCSK_KEX2_1 101 103 PF00082 0.644
CLV_PCSK_SKI1_1 101 105 PF00082 0.733
DOC_PP2B_LxvP_1 52 55 PF13499 0.756
DOC_USP7_MATH_1 55 59 PF00917 0.695
DOC_WW_Pin1_4 11 16 PF00397 0.760
DOC_WW_Pin1_4 50 55 PF00397 0.631
LIG_FHA_1 113 119 PF00498 0.559
LIG_LIR_Nem_3 84 90 PF02991 0.580
LIG_NRBOX 116 122 PF00104 0.552
LIG_SH3_3 108 114 PF00018 0.587
LIG_SH3_3 90 96 PF00018 0.603
LIG_TRAF2_1 64 67 PF00917 0.619
LIG_WW_3 47 51 PF00397 0.675
MOD_CDK_SPxxK_3 11 18 PF00069 0.706
MOD_CK1_1 16 22 PF00069 0.647
MOD_CK1_1 25 31 PF00069 0.539
MOD_CK2_1 11 17 PF00069 0.705
MOD_DYRK1A_RPxSP_1 50 54 PF00069 0.672
MOD_GlcNHglycan 57 60 PF01048 0.756
MOD_GlcNHglycan 96 99 PF01048 0.709
MOD_GSK3_1 18 25 PF00069 0.672
MOD_GSK3_1 50 57 PF00069 0.689
MOD_PKA_1 101 107 PF00069 0.654
MOD_PKA_2 101 107 PF00069 0.633
MOD_Plk_1 16 22 PF00069 0.700
MOD_Plk_1 83 89 PF00069 0.678
MOD_ProDKin_1 11 17 PF00069 0.757
MOD_ProDKin_1 50 56 PF00069 0.633
MOD_SUMO_for_1 9 12 PF00179 0.753
TRG_DiLeu_BaEn_4 66 72 PF01217 0.587
TRG_ER_diArg_1 100 102 PF00400 0.737

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PEB4 Leptomonas seymouri 57% 100%
A0A3Q8IVW6 Leishmania donovani 94% 100%
A4HP19 Leishmania braziliensis 86% 100%
A4IDC9 Leishmania infantum 94% 100%
Q4Q1R6 Leishmania major 96% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS