HSCB_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ASS1_LEIMU

TriTrypDb:

LmxM.36.1510

Length:

174

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASS1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASS1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	88	92	PF00656	0.393
CLV_NRD_NRD_1	138	140	PF00675	0.542
CLV_NRD_NRD_1	14	16	PF00675	0.624
CLV_NRD_NRD_1	38	40	PF00675	0.570
CLV_PCSK_KEX2_1	128	130	PF00082	0.395
CLV_PCSK_KEX2_1	14	16	PF00082	0.671
CLV_PCSK_KEX2_1	38	40	PF00082	0.570
CLV_PCSK_KEX2_1	64	66	PF00082	0.610
CLV_PCSK_PC1ET2_1	128	130	PF00082	0.395
CLV_PCSK_PC1ET2_1	64	66	PF00082	0.668
CLV_PCSK_SKI1_1	158	162	PF00082	0.598
CLV_PCSK_SKI1_1	78	82	PF00082	0.597
DEG_Nend_Nbox_1	1	3	PF02207	0.646
DOC_CKS1_1	72	77	PF01111	0.636
DOC_MAPK_gen_1	14	24	PF00069	0.648
DOC_MAPK_gen_1	148	157	PF00069	0.477
DOC_USP7_MATH_1	103	107	PF00917	0.405
DOC_WW_Pin1_4	28	33	PF00397	0.505
DOC_WW_Pin1_4	71	76	PF00397	0.679
LIG_14-3-3_CanoR_1	39	45	PF00244	0.579
LIG_Actin_WH2_2	30	47	PF00022	0.415
LIG_DLG_GKlike_1	129	137	PF00625	0.465
LIG_FHA_1	121	127	PF00498	0.493
LIG_FHA_1	39	45	PF00498	0.535
LIG_FHA_1	67	73	PF00498	0.527
LIG_FHA_2	108	114	PF00498	0.454
LIG_FHA_2	140	146	PF00498	0.505
LIG_FHA_2	164	170	PF00498	0.464
LIG_FHA_2	79	85	PF00498	0.507
LIG_Rb_pABgroove_1	147	155	PF01858	0.478
LIG_RPA_C_Fungi	34	46	PF08784	0.497
LIG_SH2_STAP1	153	157	PF00017	0.525
LIG_SH2_STAT5	111	114	PF00017	0.516
LIG_SH3_3	26	32	PF00018	0.559
LIG_TRAF2_1	142	145	PF00917	0.496
MOD_CDK_SPxxK_3	71	78	PF00069	0.677
MOD_CK1_1	106	112	PF00069	0.437
MOD_CK1_1	52	58	PF00069	0.499
MOD_CK2_1	107	113	PF00069	0.376
MOD_CK2_1	139	145	PF00069	0.597
MOD_CK2_1	163	169	PF00069	0.458
MOD_CK2_1	78	84	PF00069	0.572
MOD_GlcNHglycan	69	72	PF01048	0.531
MOD_GSK3_1	103	110	PF00069	0.487
MOD_GSK3_1	40	47	PF00069	0.676
MOD_GSK3_1	67	74	PF00069	0.642
MOD_N-GLC_1	4	9	PF02516	0.590
MOD_NEK2_1	44	49	PF00069	0.547
MOD_NEK2_2	40	45	PF00069	0.415
MOD_PKA_1	139	145	PF00069	0.422
MOD_PKA_1	38	44	PF00069	0.419
MOD_PKA_2	38	44	PF00069	0.595
MOD_Plk_2-3	163	169	PF00069	0.458
MOD_Plk_4	107	113	PF00069	0.454
MOD_ProDKin_1	28	34	PF00069	0.507
MOD_ProDKin_1	71	77	PF00069	0.681
MOD_SUMO_for_1	160	163	PF00179	0.530
MOD_SUMO_rev_2	132	142	PF00179	0.487
MOD_SUMO_rev_2	98	106	PF00179	0.460
TRG_DiLeu_BaEn_1	95	100	PF01217	0.386
TRG_ER_diArg_1	14	17	PF00400	0.701
TRG_ER_diArg_1	37	39	PF00400	0.562

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJJ7	Leptomonas seymouri	61%	100%
A0A3Q8IQR8	Leishmania donovani	81%	100%
A4HP11	Leishmania braziliensis	66%	99%
A4IDC0	Leishmania infantum	80%	100%
Q4Q1S5	Leishmania major	84%	100%
V5BPL2	Trypanosoma cruzi	43%	100%