CAP_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ASL7_LEIMU

TriTrypDb:

LmxM.36.0970

Length:

198

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 25

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 14

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASL7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASL7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	70	72	PF00675	0.495
CLV_NRD_NRD_1	95	97	PF00675	0.468
CLV_PCSK_SKI1_1	163	167	PF00082	0.459
CLV_PCSK_SKI1_1	17	21	PF00082	0.591
CLV_PCSK_SKI1_1	62	66	PF00082	0.463
CLV_PCSK_SKI1_1	77	81	PF00082	0.432
CLV_PCSK_SKI1_1	96	100	PF00082	0.414
DEG_APCC_DBOX_1	34	42	PF00400	0.601
DEG_APCC_DBOX_1	61	69	PF00400	0.470
DOC_CYCLIN_RxL_1	58	69	PF00134	0.475
DOC_MAPK_gen_1	71	82	PF00069	0.467
DOC_MAPK_MEF2A_6	75	84	PF00069	0.463
DOC_MAPK_NFAT4_5	77	85	PF00069	0.461
DOC_PP1_RVXF_1	79	85	PF00149	0.442
DOC_SPAK_OSR1_1	144	148	PF12202	0.446
DOC_USP7_UBL2_3	189	193	PF12436	0.666
LIG_14-3-3_CanoR_1	17	22	PF00244	0.711
LIG_Actin_WH2_2	4	19	PF00022	0.638
LIG_Actin_WH2_2	85	102	PF00022	0.537
LIG_BIR_II_1	1	5	PF00653	0.569
LIG_FHA_1	105	111	PF00498	0.463
LIG_FHA_1	114	120	PF00498	0.511
LIG_FHA_1	122	128	PF00498	0.446
LIG_FHA_2	18	24	PF00498	0.482
LIG_FHA_2	54	60	PF00498	0.463
LIG_FHA_2	84	90	PF00498	0.489
LIG_Integrin_isoDGR_2	94	96	PF01839	0.478
LIG_LIR_Nem_3	136	142	PF02991	0.425
LIG_NRBOX	63	69	PF00104	0.526
LIG_Pex14_2	182	186	PF04695	0.478
LIG_Pex14_2	84	88	PF04695	0.418
LIG_PTB_Apo_2	180	187	PF02174	0.483
LIG_SUMO_SIM_par_1	122	131	PF11976	0.572
LIG_SUMO_SIM_par_1	63	69	PF11976	0.577
LIG_TRAF2_1	128	131	PF00917	0.465
LIG_UBA3_1	181	189	PF00899	0.493
LIG_UBA3_1	64	72	PF00899	0.469
LIG_WRC_WIRS_1	85	90	PF05994	0.420
MOD_CK1_1	105	111	PF00069	0.508
MOD_CK1_1	2	8	PF00069	0.540
MOD_CK2_1	100	106	PF00069	0.633
MOD_CK2_1	125	131	PF00069	0.562
MOD_CK2_1	53	59	PF00069	0.477
MOD_CK2_1	83	89	PF00069	0.511
MOD_Cter_Amidation	94	97	PF01082	0.463
MOD_GlcNHglycan	102	105	PF01048	0.596
MOD_GlcNHglycan	148	151	PF01048	0.579
MOD_GSK3_1	100	107	PF00069	0.556
MOD_GSK3_1	121	128	PF00069	0.478
MOD_GSK3_1	40	47	PF00069	0.396
MOD_N-GLC_1	9	14	PF02516	0.611
MOD_NEK2_1	188	193	PF00069	0.518
MOD_NEK2_1	9	14	PF00069	0.631
MOD_NEK2_1	99	104	PF00069	0.498
MOD_PIKK_1	44	50	PF00454	0.398
MOD_PIKK_1	9	15	PF00454	0.641
MOD_PK_1	115	121	PF00069	0.558
MOD_PKB_1	15	23	PF00069	0.599
MOD_Plk_1	105	111	PF00069	0.437
MOD_Plk_1	121	127	PF00069	0.456
MOD_Plk_2-3	53	59	PF00069	0.560
MOD_SUMO_for_1	54	57	PF00179	0.487
MOD_SUMO_rev_2	47	56	PF00179	0.432
TRG_DiLeu_BaEn_2	140	146	PF01217	0.415
TRG_DiLeu_BaEn_2	152	158	PF01217	0.451
TRG_DiLeu_BaEn_4	130	136	PF01217	0.437
TRG_NES_CRM1_1	137	148	PF08389	0.428
TRG_Pf-PMV_PEXEL_1	62	66	PF00026	0.454

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IHX7	Leptomonas seymouri	86%	100%
A0A0S4JAX8	Bodo saltans	26%	89%
A0A1X0P947	Trypanosomatidae	67%	98%
A0A3S5H817	Leishmania donovani	98%	87%
A0A422NTY7	Trypanosoma rangeli	69%	97%
A4HNV6	Leishmania braziliensis	91%	100%
A4ICN7	Leishmania infantum	98%	87%
Q4Q1X9	Leishmania major	97%	100%
V5B9W8	Trypanosoma cruzi	64%	97%