LeishMANIAdb
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Guanylate cyclase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Guanylate cyclase
Gene product:
mitogen-activated protein kinase-like protein
Species:
Leishmania mexicana
UniProt:
E9ASL1_LEIMU
TriTrypDb:
LmxM.36.0910
Length:
1563

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

E9ASL1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 7
GO:0006163 purine nucleotide metabolic process 5 7
GO:0006164 purine nucleotide biosynthetic process 6 7
GO:0006171 cAMP biosynthetic process 8 7
GO:0006182 cGMP biosynthetic process 8 7
GO:0006468 protein phosphorylation 5 7
GO:0006725 cellular aromatic compound metabolic process 3 7
GO:0006753 nucleoside phosphate metabolic process 4 7
GO:0006793 phosphorus metabolic process 3 7
GO:0006796 phosphate-containing compound metabolic process 4 7
GO:0006807 nitrogen compound metabolic process 2 7
GO:0008152 metabolic process 1 7
GO:0009058 biosynthetic process 2 7
GO:0009117 nucleotide metabolic process 5 7
GO:0009150 purine ribonucleotide metabolic process 6 7
GO:0009152 purine ribonucleotide biosynthetic process 7 7
GO:0009165 nucleotide biosynthetic process 6 7
GO:0009187 cyclic nucleotide metabolic process 6 7
GO:0009190 cyclic nucleotide biosynthetic process 7 7
GO:0009259 ribonucleotide metabolic process 5 7
GO:0009260 ribonucleotide biosynthetic process 6 7
GO:0009987 cellular process 1 7
GO:0016310 phosphorylation 5 7
GO:0018130 heterocycle biosynthetic process 4 7
GO:0019438 aromatic compound biosynthetic process 4 7
GO:0019538 protein metabolic process 3 7
GO:0019637 organophosphate metabolic process 3 7
GO:0019693 ribose phosphate metabolic process 4 7
GO:0034641 cellular nitrogen compound metabolic process 3 7
GO:0034654 nucleobase-containing compound biosynthetic process 4 7
GO:0036211 protein modification process 4 7
GO:0043170 macromolecule metabolic process 3 7
GO:0043412 macromolecule modification 4 7
GO:0044237 cellular metabolic process 2 7
GO:0044238 primary metabolic process 2 7
GO:0044249 cellular biosynthetic process 3 7
GO:0044271 cellular nitrogen compound biosynthetic process 4 7
GO:0044281 small molecule metabolic process 2 7
GO:0046058 cAMP metabolic process 7 7
GO:0046068 cGMP metabolic process 7 7
GO:0046390 ribose phosphate biosynthetic process 5 7
GO:0046483 heterocycle metabolic process 3 7
GO:0052652 cyclic purine nucleotide metabolic process 6 7
GO:0055086 nucleobase-containing small molecule metabolic process 3 7
GO:0071704 organic substance metabolic process 2 7
GO:0072521 purine-containing compound metabolic process 4 7
GO:0072522 purine-containing compound biosynthetic process 5 7
GO:0090407 organophosphate biosynthetic process 4 7
GO:1901135 carbohydrate derivative metabolic process 3 7
GO:1901137 carbohydrate derivative biosynthetic process 4 7
GO:1901293 nucleoside phosphate biosynthetic process 5 7
GO:1901360 organic cyclic compound metabolic process 3 7
GO:1901362 organic cyclic compound biosynthetic process 4 7
GO:1901564 organonitrogen compound metabolic process 3 7
GO:1901566 organonitrogen compound biosynthetic process 4 7
GO:1901576 organic substance biosynthetic process 3 7
GO:0007165 signal transduction 2 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0065007 biological regulation 1 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 7
GO:0003824 catalytic activity 1 7
GO:0004672 protein kinase activity 3 7
GO:0005488 binding 1 7
GO:0005524 ATP binding 5 7
GO:0016301 kinase activity 4 7
GO:0016740 transferase activity 2 7
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 7
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 7
GO:0017076 purine nucleotide binding 4 7
GO:0030554 adenyl nucleotide binding 5 7
GO:0032553 ribonucleotide binding 3 7
GO:0032555 purine ribonucleotide binding 4 7
GO:0032559 adenyl ribonucleotide binding 5 7
GO:0035639 purine ribonucleoside triphosphate binding 4 7
GO:0036094 small molecule binding 2 7
GO:0043167 ion binding 2 7
GO:0043168 anion binding 3 7
GO:0097159 organic cyclic compound binding 2 7
GO:0097367 carbohydrate derivative binding 2 7
GO:0140096 catalytic activity, acting on a protein 2 7
GO:1901265 nucleoside phosphate binding 3 7
GO:1901363 heterocyclic compound binding 2 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1448 1452 PF00656 0.619
CLV_C14_Caspase3-7 33 37 PF00656 0.593
CLV_C14_Caspase3-7 419 423 PF00656 0.232
CLV_C14_Caspase3-7 435 439 PF00656 0.210
CLV_C14_Caspase3-7 774 778 PF00656 0.626
CLV_MEL_PAP_1 545 551 PF00089 0.529
CLV_NRD_NRD_1 1089 1091 PF00675 0.402
CLV_NRD_NRD_1 1209 1211 PF00675 0.466
CLV_NRD_NRD_1 1398 1400 PF00675 0.346
CLV_NRD_NRD_1 1551 1553 PF00675 0.394
CLV_NRD_NRD_1 172 174 PF00675 0.476
CLV_NRD_NRD_1 290 292 PF00675 0.520
CLV_NRD_NRD_1 432 434 PF00675 0.598
CLV_NRD_NRD_1 63 65 PF00675 0.396
CLV_NRD_NRD_1 641 643 PF00675 0.302
CLV_NRD_NRD_1 703 705 PF00675 0.377
CLV_NRD_NRD_1 962 964 PF00675 0.515
CLV_NRD_NRD_1 971 973 PF00675 0.396
CLV_NRD_NRD_1 980 982 PF00675 0.267
CLV_NRD_NRD_1 998 1000 PF00675 0.393
CLV_PCSK_FUR_1 639 643 PF00082 0.305
CLV_PCSK_KEX2_1 1027 1029 PF00082 0.500
CLV_PCSK_KEX2_1 1089 1091 PF00082 0.402
CLV_PCSK_KEX2_1 1209 1211 PF00082 0.466
CLV_PCSK_KEX2_1 1551 1553 PF00082 0.394
CLV_PCSK_KEX2_1 171 173 PF00082 0.479
CLV_PCSK_KEX2_1 432 434 PF00082 0.614
CLV_PCSK_KEX2_1 638 640 PF00082 0.459
CLV_PCSK_KEX2_1 641 643 PF00082 0.428
CLV_PCSK_KEX2_1 703 705 PF00082 0.366
CLV_PCSK_KEX2_1 962 964 PF00082 0.515
CLV_PCSK_KEX2_1 971 973 PF00082 0.396
CLV_PCSK_KEX2_1 980 982 PF00082 0.267
CLV_PCSK_KEX2_1 998 1000 PF00082 0.387
CLV_PCSK_PC1ET2_1 1027 1029 PF00082 0.500
CLV_PCSK_PC1ET2_1 638 640 PF00082 0.459
CLV_PCSK_PC7_1 699 705 PF00082 0.320
CLV_PCSK_SKI1_1 1031 1035 PF00082 0.313
CLV_PCSK_SKI1_1 1151 1155 PF00082 0.585
CLV_PCSK_SKI1_1 256 260 PF00082 0.575
CLV_PCSK_SKI1_1 278 282 PF00082 0.603
CLV_PCSK_SKI1_1 535 539 PF00082 0.550
CLV_PCSK_SKI1_1 641 645 PF00082 0.430
CLV_PCSK_SKI1_1 654 658 PF00082 0.370
CLV_PCSK_SKI1_1 677 681 PF00082 0.372
CLV_PCSK_SKI1_1 943 947 PF00082 0.371
DEG_APCC_DBOX_1 1088 1096 PF00400 0.684
DEG_APCC_DBOX_1 202 210 PF00400 0.596
DEG_APCC_DBOX_1 277 285 PF00400 0.405
DEG_APCC_DBOX_1 44 52 PF00400 0.561
DEG_MDM2_SWIB_1 307 315 PF02201 0.349
DEG_SCF_FBW7_1 1455 1462 PF00400 0.619
DEG_SPOP_SBC_1 1094 1098 PF00917 0.464
DEG_SPOP_SBC_1 1255 1259 PF00917 0.582
DEG_SPOP_SBC_1 128 132 PF00917 0.587
DEG_SPOP_SBC_1 2 6 PF00917 0.691
DOC_CYCLIN_yClb1_LxF_4 278 284 PF00134 0.323
DOC_MAPK_gen_1 1027 1038 PF00069 0.518
DOC_MAPK_gen_1 1399 1407 PF00069 0.546
DOC_MAPK_gen_1 208 217 PF00069 0.631
DOC_MAPK_gen_1 291 298 PF00069 0.357
DOC_MAPK_gen_1 43 51 PF00069 0.566
DOC_MAPK_gen_1 463 472 PF00069 0.386
DOC_MAPK_gen_1 703 709 PF00069 0.515
DOC_MAPK_gen_1 758 766 PF00069 0.577
DOC_MAPK_gen_1 837 845 PF00069 0.514
DOC_MAPK_HePTP_8 209 221 PF00069 0.619
DOC_MAPK_MEF2A_6 210 219 PF00069 0.619
DOC_MAPK_MEF2A_6 43 51 PF00069 0.594
DOC_MAPK_MEF2A_6 587 595 PF00069 0.363
DOC_MAPK_MEF2A_6 760 768 PF00069 0.586
DOC_MAPK_MEF2A_6 839 847 PF00069 0.517
DOC_PP1_RVXF_1 529 535 PF00149 0.221
DOC_PP1_RVXF_1 999 1005 PF00149 0.603
DOC_PP2B_LxvP_1 303 306 PF13499 0.421
DOC_PP4_FxxP_1 1461 1464 PF00568 0.546
DOC_PP4_FxxP_1 382 385 PF00568 0.287
DOC_PP4_FxxP_1 816 819 PF00568 0.576
DOC_PP4_FxxP_1 90 93 PF00568 0.554
DOC_SPAK_OSR1_1 561 565 PF12202 0.218
DOC_USP7_MATH_1 102 106 PF00917 0.614
DOC_USP7_MATH_1 1093 1097 PF00917 0.620
DOC_USP7_MATH_1 122 126 PF00917 0.549
DOC_USP7_MATH_1 1256 1260 PF00917 0.728
DOC_USP7_MATH_1 140 144 PF00917 0.700
DOC_USP7_MATH_1 2 6 PF00917 0.718
DOC_USP7_MATH_1 37 41 PF00917 0.610
DOC_USP7_MATH_1 537 541 PF00917 0.291
DOC_USP7_MATH_1 775 779 PF00917 0.640
DOC_USP7_UBL2_3 943 947 PF12436 0.571
DOC_WW_Pin1_4 1180 1185 PF00397 0.740
DOC_WW_Pin1_4 1220 1225 PF00397 0.681
DOC_WW_Pin1_4 123 128 PF00397 0.665
DOC_WW_Pin1_4 1251 1256 PF00397 0.614
DOC_WW_Pin1_4 135 140 PF00397 0.747
DOC_WW_Pin1_4 141 146 PF00397 0.782
DOC_WW_Pin1_4 1455 1460 PF00397 0.619
DOC_WW_Pin1_4 73 78 PF00397 0.606
DOC_WW_Pin1_4 933 938 PF00397 0.642
DOC_WW_Pin1_4 971 976 PF00397 0.604
LIG_14-3-3_CanoR_1 103 111 PF00244 0.684
LIG_14-3-3_CanoR_1 1031 1037 PF00244 0.640
LIG_14-3-3_CanoR_1 1293 1298 PF00244 0.595
LIG_14-3-3_CanoR_1 1460 1464 PF00244 0.531
LIG_14-3-3_CanoR_1 1513 1517 PF00244 0.619
LIG_14-3-3_CanoR_1 203 207 PF00244 0.626
LIG_14-3-3_CanoR_1 278 284 PF00244 0.398
LIG_14-3-3_CanoR_1 285 289 PF00244 0.347
LIG_14-3-3_CanoR_1 432 437 PF00244 0.293
LIG_14-3-3_CanoR_1 548 556 PF00244 0.252
LIG_14-3-3_CanoR_1 64 74 PF00244 0.643
LIG_14-3-3_CanoR_1 654 662 PF00244 0.524
LIG_14-3-3_CanoR_1 758 766 PF00244 0.577
LIG_APCC_ABBA_1 553 558 PF00400 0.301
LIG_APCC_ABBA_1 909 914 PF00400 0.557
LIG_BRCT_BRCA1_1 1062 1066 PF00533 0.533
LIG_BRCT_BRCA1_1 1096 1100 PF00533 0.605
LIG_BRCT_BRCA1_1 1182 1186 PF00533 0.635
LIG_BRCT_BRCA1_1 363 367 PF00533 0.228
LIG_BRCT_BRCA1_1 446 450 PF00533 0.405
LIG_BRCT_BRCA1_1 468 472 PF00533 0.351
LIG_BRCT_BRCA1_1 688 692 PF00533 0.635
LIG_deltaCOP1_diTrp_1 309 314 PF00928 0.366
LIG_deltaCOP1_diTrp_1 451 457 PF00928 0.437
LIG_EH1_1 513 521 PF00400 0.232
LIG_EH1_1 921 929 PF00400 0.569
LIG_eIF4E_1 1401 1407 PF01652 0.546
LIG_FHA_1 1033 1039 PF00498 0.681
LIG_FHA_1 1196 1202 PF00498 0.749
LIG_FHA_1 13 19 PF00498 0.714
LIG_FHA_1 1303 1309 PF00498 0.626
LIG_FHA_1 1322 1328 PF00498 0.404
LIG_FHA_1 1432 1438 PF00498 0.546
LIG_FHA_1 1516 1522 PF00498 0.411
LIG_FHA_1 321 327 PF00498 0.364
LIG_FHA_1 426 432 PF00498 0.400
LIG_FHA_1 520 526 PF00498 0.345
LIG_FHA_1 544 550 PF00498 0.393
LIG_FHA_1 760 766 PF00498 0.563
LIG_FHA_1 890 896 PF00498 0.624
LIG_FHA_2 1496 1502 PF00498 0.563
LIG_FHA_2 1552 1558 PF00498 0.546
LIG_FHA_2 181 187 PF00498 0.588
LIG_FHA_2 31 37 PF00498 0.587
LIG_FHA_2 335 341 PF00498 0.222
LIG_FHA_2 417 423 PF00498 0.275
LIG_FHA_2 502 508 PF00498 0.288
LIG_FHA_2 655 661 PF00498 0.564
LIG_FHA_2 855 861 PF00498 0.606
LIG_IRF3_LxIS_1 1317 1322 PF10401 0.483
LIG_LIR_Apic_2 1193 1197 PF02991 0.546
LIG_LIR_Apic_2 1458 1464 PF02991 0.546
LIG_LIR_Apic_2 380 385 PF02991 0.286
LIG_LIR_Apic_2 814 819 PF02991 0.578
LIG_LIR_Gen_1 1042 1048 PF02991 0.488
LIG_LIR_Gen_1 1316 1323 PF02991 0.619
LIG_LIR_Gen_1 325 335 PF02991 0.445
LIG_LIR_Gen_1 451 461 PF02991 0.423
LIG_LIR_Gen_1 466 473 PF02991 0.284
LIG_LIR_Gen_1 558 564 PF02991 0.357
LIG_LIR_Gen_1 588 598 PF02991 0.363
LIG_LIR_Gen_1 665 673 PF02991 0.560
LIG_LIR_Gen_1 804 812 PF02991 0.554
LIG_LIR_LC3C_4 761 766 PF02991 0.652
LIG_LIR_Nem_3 1042 1047 PF02991 0.540
LIG_LIR_Nem_3 1057 1061 PF02991 0.638
LIG_LIR_Nem_3 1103 1109 PF02991 0.603
LIG_LIR_Nem_3 1313 1317 PF02991 0.546
LIG_LIR_Nem_3 1368 1374 PF02991 0.546
LIG_LIR_Nem_3 389 394 PF02991 0.405
LIG_LIR_Nem_3 451 457 PF02991 0.421
LIG_LIR_Nem_3 466 471 PF02991 0.287
LIG_LIR_Nem_3 558 562 PF02991 0.358
LIG_LIR_Nem_3 588 593 PF02991 0.406
LIG_LIR_Nem_3 665 669 PF02991 0.559
LIG_LIR_Nem_3 804 808 PF02991 0.550
LIG_LIR_Nem_3 849 854 PF02991 0.568
LIG_LIR_Nem_3 944 949 PF02991 0.573
LIG_MLH1_MIPbox_1 446 450 PF16413 0.366
LIG_NRBOX 1557 1563 PF00104 0.721
LIG_NRBOX 216 222 PF00104 0.513
LIG_PCNA_yPIPBox_3 432 441 PF02747 0.440
LIG_Pex14_1 453 457 PF04695 0.368
LIG_Pex14_1 534 538 PF04695 0.226
LIG_Pex14_2 307 311 PF04695 0.348
LIG_Pex14_2 449 453 PF04695 0.337
LIG_Pex14_2 812 816 PF04695 0.579
LIG_PTB_Apo_2 236 243 PF02174 0.387
LIG_PTB_Apo_2 298 305 PF02174 0.312
LIG_PTB_Apo_2 660 667 PF02174 0.613
LIG_PTB_Phospho_1 236 242 PF10480 0.385
LIG_PTB_Phospho_1 298 304 PF10480 0.312
LIG_REV1ctd_RIR_1 388 394 PF16727 0.216
LIG_REV1ctd_RIR_1 447 456 PF16727 0.374
LIG_SH2_CRK 1288 1292 PF00017 0.597
LIG_SH2_CRK 242 246 PF00017 0.389
LIG_SH2_CRK 468 472 PF00017 0.249
LIG_SH2_CRK 577 581 PF00017 0.359
LIG_SH2_CRK 851 855 PF00017 0.537
LIG_SH2_CRK 932 936 PF00017 0.590
LIG_SH2_NCK_1 1497 1501 PF00017 0.619
LIG_SH2_PTP2 393 396 PF00017 0.300
LIG_SH2_STAP1 1361 1365 PF00017 0.546
LIG_SH2_STAP1 1401 1405 PF00017 0.546
LIG_SH2_STAP1 316 320 PF00017 0.273
LIG_SH2_STAP1 468 472 PF00017 0.249
LIG_SH2_STAT3 1411 1414 PF00017 0.546
LIG_SH2_STAT3 316 319 PF00017 0.218
LIG_SH2_STAT3 997 1000 PF00017 0.586
LIG_SH2_STAT5 1060 1063 PF00017 0.485
LIG_SH2_STAT5 1235 1238 PF00017 0.518
LIG_SH2_STAT5 1318 1321 PF00017 0.546
LIG_SH2_STAT5 1377 1380 PF00017 0.555
LIG_SH2_STAT5 1411 1414 PF00017 0.546
LIG_SH2_STAT5 1497 1500 PF00017 0.573
LIG_SH2_STAT5 242 245 PF00017 0.419
LIG_SH2_STAT5 304 307 PF00017 0.421
LIG_SH2_STAT5 327 330 PF00017 0.451
LIG_SH2_STAT5 393 396 PF00017 0.356
LIG_SH2_STAT5 411 414 PF00017 0.360
LIG_SH2_STAT5 853 856 PF00017 0.560
LIG_SH2_STAT5 884 887 PF00017 0.542
LIG_SH3_1 972 978 PF00018 0.642
LIG_SH3_2 975 980 PF14604 0.708
LIG_SH3_3 1152 1158 PF00018 0.773
LIG_SH3_3 1182 1188 PF00018 0.719
LIG_SH3_3 121 127 PF00018 0.709
LIG_SH3_3 1523 1529 PF00018 0.546
LIG_SH3_3 346 352 PF00018 0.299
LIG_SH3_3 48 54 PF00018 0.632
LIG_SH3_3 497 503 PF00018 0.350
LIG_SH3_3 675 681 PF00018 0.570
LIG_SH3_3 71 77 PF00018 0.643
LIG_SH3_3 739 745 PF00018 0.519
LIG_SH3_3 931 937 PF00018 0.589
LIG_SH3_3 972 978 PF00018 0.638
LIG_SUMO_SIM_anti_2 152 160 PF11976 0.545
LIG_SUMO_SIM_anti_2 1556 1563 PF11976 0.716
LIG_SUMO_SIM_anti_2 261 267 PF11976 0.389
LIG_SUMO_SIM_anti_2 294 300 PF11976 0.308
LIG_SUMO_SIM_anti_2 414 422 PF11976 0.229
LIG_SUMO_SIM_anti_2 438 445 PF11976 0.418
LIG_SUMO_SIM_anti_2 761 767 PF11976 0.653
LIG_SUMO_SIM_anti_2 777 783 PF11976 0.455
LIG_SUMO_SIM_par_1 1034 1040 PF11976 0.535
LIG_SUMO_SIM_par_1 116 121 PF11976 0.544
LIG_SUMO_SIM_par_1 152 160 PF11976 0.682
LIG_SUMO_SIM_par_1 1556 1563 PF11976 0.716
LIG_SUMO_SIM_par_1 438 445 PF11976 0.365
LIG_SUMO_SIM_par_1 620 626 PF11976 0.551
LIG_SUMO_SIM_par_1 761 767 PF11976 0.581
LIG_SUMO_SIM_par_1 798 804 PF11976 0.637
LIG_TRAF2_1 1162 1165 PF00917 0.554
LIG_TRAF2_1 1554 1557 PF00917 0.546
LIG_TRAF2_2 145 150 PF00917 0.545
LIG_UBA3_1 263 267 PF00899 0.257
LIG_WRC_WIRS_1 1041 1046 PF05994 0.332
LIG_WRC_WIRS_1 1477 1482 PF05994 0.411
LIG_WRC_WIRS_1 280 285 PF05994 0.503
LIG_WRC_WIRS_1 387 392 PF05994 0.253
LIG_WRC_WIRS_1 520 525 PF05994 0.462
LIG_WRC_WIRS_1 809 814 PF05994 0.444
LIG_WRPW_2 676 679 PF00400 0.423
LIG_WW_3 76 80 PF00397 0.457
MOD_CDC14_SPxK_1 76 79 PF00782 0.340
MOD_CDK_SPK_2 1455 1460 PF00069 0.513
MOD_CDK_SPxK_1 73 79 PF00069 0.351
MOD_CK1_1 1023 1029 PF00069 0.587
MOD_CK1_1 1037 1043 PF00069 0.329
MOD_CK1_1 1083 1089 PF00069 0.566
MOD_CK1_1 1122 1128 PF00069 0.804
MOD_CK1_1 1199 1205 PF00069 0.721
MOD_CK1_1 1254 1260 PF00069 0.748
MOD_CK1_1 143 149 PF00069 0.646
MOD_CK1_1 1431 1437 PF00069 0.411
MOD_CK1_1 1515 1521 PF00069 0.513
MOD_CK1_1 175 181 PF00069 0.592
MOD_CK1_1 3 9 PF00069 0.783
MOD_CK1_1 322 328 PF00069 0.425
MOD_CK1_1 626 632 PF00069 0.568
MOD_CK1_1 683 689 PF00069 0.451
MOD_CK1_1 811 817 PF00069 0.455
MOD_CK1_1 877 883 PF00069 0.453
MOD_CK2_1 1067 1073 PF00069 0.531
MOD_CK2_1 1127 1133 PF00069 0.515
MOD_CK2_1 1310 1316 PF00069 0.513
MOD_CK2_1 1317 1323 PF00069 0.397
MOD_CK2_1 1459 1465 PF00069 0.411
MOD_CK2_1 1551 1557 PF00069 0.411
MOD_CK2_1 188 194 PF00069 0.591
MOD_CK2_1 3 9 PF00069 0.635
MOD_CK2_1 445 451 PF00069 0.386
MOD_CK2_1 501 507 PF00069 0.335
MOD_CK2_1 541 547 PF00069 0.250
MOD_CK2_1 57 63 PF00069 0.490
MOD_CK2_1 854 860 PF00069 0.493
MOD_CMANNOS 311 314 PF00535 0.518
MOD_Cter_Amidation 1207 1210 PF01082 0.465
MOD_GlcNHglycan 105 108 PF01048 0.521
MOD_GlcNHglycan 1198 1201 PF01048 0.431
MOD_GlcNHglycan 1237 1240 PF01048 0.619
MOD_GlcNHglycan 1244 1247 PF01048 0.725
MOD_GlcNHglycan 1258 1261 PF01048 0.730
MOD_GlcNHglycan 1268 1271 PF01048 0.597
MOD_GlcNHglycan 1461 1464 PF01048 0.411
MOD_GlcNHglycan 1538 1541 PF01048 0.513
MOD_GlcNHglycan 252 255 PF01048 0.511
MOD_GlcNHglycan 496 499 PF01048 0.518
MOD_GlcNHglycan 5 8 PF01048 0.562
MOD_GlcNHglycan 657 660 PF01048 0.537
MOD_GlcNHglycan 794 797 PF01048 0.335
MOD_GlcNHglycan 848 851 PF01048 0.446
MOD_GlcNHglycan 994 997 PF01048 0.402
MOD_GSK3_1 1 8 PF00069 0.611
MOD_GSK3_1 1046 1053 PF00069 0.363
MOD_GSK3_1 1107 1114 PF00069 0.466
MOD_GSK3_1 1122 1129 PF00069 0.701
MOD_GSK3_1 1174 1181 PF00069 0.614
MOD_GSK3_1 1195 1202 PF00069 0.608
MOD_GSK3_1 123 130 PF00069 0.533
MOD_GSK3_1 1251 1258 PF00069 0.748
MOD_GSK3_1 1317 1324 PF00069 0.484
MOD_GSK3_1 1427 1434 PF00069 0.485
MOD_GSK3_1 1441 1448 PF00069 0.309
MOD_GSK3_1 1451 1458 PF00069 0.411
MOD_GSK3_1 1476 1483 PF00069 0.411
MOD_GSK3_1 1547 1554 PF00069 0.222
MOD_GSK3_1 279 286 PF00069 0.539
MOD_GSK3_1 310 317 PF00069 0.434
MOD_GSK3_1 322 329 PF00069 0.410
MOD_GSK3_1 351 358 PF00069 0.382
MOD_GSK3_1 412 419 PF00069 0.348
MOD_GSK3_1 537 544 PF00069 0.329
MOD_GSK3_1 623 630 PF00069 0.456
MOD_GSK3_1 65 72 PF00069 0.507
MOD_GSK3_1 686 693 PF00069 0.532
MOD_GSK3_1 734 741 PF00069 0.564
MOD_GSK3_1 876 883 PF00069 0.361
MOD_GSK3_1 885 892 PF00069 0.369
MOD_N-GLC_1 1020 1025 PF02516 0.626
MOD_N-GLC_1 1495 1500 PF02516 0.222
MOD_N-GLC_1 259 264 PF02516 0.448
MOD_N-GLC_1 367 372 PF02516 0.418
MOD_N-GLC_1 402 407 PF02516 0.337
MOD_N-GLC_1 841 846 PF02516 0.256
MOD_NEK2_1 1032 1037 PF00069 0.644
MOD_NEK2_1 1085 1090 PF00069 0.537
MOD_NEK2_1 1126 1131 PF00069 0.605
MOD_NEK2_1 1302 1307 PF00069 0.433
MOD_NEK2_1 1445 1450 PF00069 0.411
MOD_NEK2_1 1480 1485 PF00069 0.411
MOD_NEK2_1 259 264 PF00069 0.448
MOD_NEK2_1 283 288 PF00069 0.580
MOD_NEK2_1 315 320 PF00069 0.433
MOD_NEK2_1 344 349 PF00069 0.413
MOD_NEK2_1 367 372 PF00069 0.361
MOD_NEK2_1 519 524 PF00069 0.343
MOD_NEK2_1 581 586 PF00069 0.523
MOD_NEK2_1 685 690 PF00069 0.511
MOD_NEK2_1 738 743 PF00069 0.625
MOD_NEK2_1 756 761 PF00069 0.351
MOD_NEK2_1 764 769 PF00069 0.467
MOD_NEK2_1 785 790 PF00069 0.455
MOD_NEK2_1 868 873 PF00069 0.561
MOD_NEK2_1 885 890 PF00069 0.376
MOD_NEK2_1 941 946 PF00069 0.407
MOD_NEK2_1 992 997 PF00069 0.454
MOD_NEK2_2 1107 1112 PF00069 0.565
MOD_NEK2_2 269 274 PF00069 0.465
MOD_PIKK_1 1119 1125 PF00454 0.623
MOD_PIKK_1 1127 1133 PF00454 0.701
MOD_PIKK_1 12 18 PF00454 0.621
MOD_PIKK_1 1303 1309 PF00454 0.513
MOD_PIKK_1 1348 1354 PF00454 0.383
MOD_PIKK_1 143 149 PF00454 0.492
MOD_PIKK_1 315 321 PF00454 0.231
MOD_PIKK_1 367 373 PF00454 0.332
MOD_PIKK_1 623 629 PF00454 0.485
MOD_PK_1 1293 1299 PF00069 0.484
MOD_PK_1 292 298 PF00069 0.364
MOD_PK_1 432 438 PF00069 0.256
MOD_PKA_1 1551 1557 PF00069 0.513
MOD_PKA_1 172 178 PF00069 0.589
MOD_PKA_1 432 438 PF00069 0.256
MOD_PKA_1 464 470 PF00069 0.472
MOD_PKA_2 102 108 PF00069 0.604
MOD_PKA_2 1111 1117 PF00069 0.441
MOD_PKA_2 1126 1132 PF00069 0.597
MOD_PKA_2 1133 1139 PF00069 0.556
MOD_PKA_2 1303 1309 PF00069 0.411
MOD_PKA_2 1310 1316 PF00069 0.411
MOD_PKA_2 1459 1465 PF00069 0.411
MOD_PKA_2 1512 1518 PF00069 0.513
MOD_PKA_2 1551 1557 PF00069 0.411
MOD_PKA_2 172 178 PF00069 0.589
MOD_PKA_2 202 208 PF00069 0.517
MOD_PKA_2 284 290 PF00069 0.406
MOD_PKA_2 29 35 PF00069 0.455
MOD_PKA_2 432 438 PF00069 0.256
MOD_PKA_2 547 553 PF00069 0.241
MOD_Plk_1 1020 1026 PF00069 0.598
MOD_Plk_1 259 265 PF00069 0.448
MOD_Plk_1 367 373 PF00069 0.468
MOD_Plk_1 444 450 PF00069 0.429
MOD_Plk_1 541 547 PF00069 0.340
MOD_Plk_1 581 587 PF00069 0.523
MOD_Plk_1 841 847 PF00069 0.256
MOD_Plk_2-3 1133 1139 PF00069 0.639
MOD_Plk_2-3 416 422 PF00069 0.245
MOD_Plk_2-3 445 451 PF00069 0.324
MOD_Plk_4 1200 1206 PF00069 0.644
MOD_Plk_4 1382 1388 PF00069 0.513
MOD_Plk_4 1413 1419 PF00069 0.513
MOD_Plk_4 1557 1563 PF00069 0.555
MOD_Plk_4 163 169 PF00069 0.342
MOD_Plk_4 259 265 PF00069 0.535
MOD_Plk_4 279 285 PF00069 0.251
MOD_Plk_4 310 316 PF00069 0.396
MOD_Plk_4 322 328 PF00069 0.546
MOD_Plk_4 344 350 PF00069 0.385
MOD_Plk_4 386 392 PF00069 0.277
MOD_Plk_4 416 422 PF00069 0.368
MOD_Plk_4 432 438 PF00069 0.436
MOD_Plk_4 445 451 PF00069 0.356
MOD_Plk_4 466 472 PF00069 0.425
MOD_Plk_4 474 480 PF00069 0.436
MOD_Plk_4 680 686 PF00069 0.456
MOD_Plk_4 759 765 PF00069 0.452
MOD_Plk_4 785 791 PF00069 0.453
MOD_Plk_4 868 874 PF00069 0.557
MOD_Plk_4 880 886 PF00069 0.238
MOD_Plk_4 941 947 PF00069 0.431
MOD_ProDKin_1 1180 1186 PF00069 0.684
MOD_ProDKin_1 1220 1226 PF00069 0.595
MOD_ProDKin_1 123 129 PF00069 0.578
MOD_ProDKin_1 1251 1257 PF00069 0.504
MOD_ProDKin_1 135 141 PF00069 0.695
MOD_ProDKin_1 1455 1461 PF00069 0.513
MOD_ProDKin_1 73 79 PF00069 0.493
MOD_ProDKin_1 933 939 PF00069 0.544
MOD_ProDKin_1 971 977 PF00069 0.493
MOD_SUMO_for_1 10 13 PF00179 0.478
MOD_SUMO_for_1 1422 1425 PF00179 0.513
MOD_SUMO_rev_2 1416 1424 PF00179 0.411
MOD_SUMO_rev_2 175 181 PF00179 0.584
MOD_SUMO_rev_2 286 293 PF00179 0.268
MOD_SUMO_rev_2 3 12 PF00179 0.516
MOD_SUMO_rev_2 416 425 PF00179 0.370
MOD_SUMO_rev_2 565 569 PF00179 0.415
MOD_SUMO_rev_2 60 66 PF00179 0.465
TRG_DiLeu_BaEn_1 1557 1562 PF01217 0.663
TRG_DiLeu_BaEn_1 185 190 PF01217 0.597
TRG_DiLeu_BaEn_1 747 752 PF01217 0.524
TRG_DiLeu_BaEn_1 987 992 PF01217 0.448
TRG_DiLeu_BaLyEn_6 331 336 PF01217 0.250
TRG_DiLeu_LyEn_5 747 752 PF01217 0.524
TRG_ENDOCYTIC_2 1318 1321 PF00928 0.411
TRG_ENDOCYTIC_2 242 245 PF00928 0.491
TRG_ENDOCYTIC_2 304 307 PF00928 0.468
TRG_ENDOCYTIC_2 327 330 PF00928 0.559
TRG_ENDOCYTIC_2 393 396 PF00928 0.448
TRG_ENDOCYTIC_2 409 412 PF00928 0.319
TRG_ENDOCYTIC_2 468 471 PF00928 0.352
TRG_ENDOCYTIC_2 556 559 PF00928 0.413
TRG_ENDOCYTIC_2 676 679 PF00928 0.423
TRG_ENDOCYTIC_2 851 854 PF00928 0.438
TRG_ENDOCYTIC_2 932 935 PF00928 0.473
TRG_ER_diArg_1 1551 1553 PF00400 0.474
TRG_ER_diArg_1 170 173 PF00400 0.586
TRG_ER_diArg_1 431 433 PF00400 0.490
TRG_ER_diArg_1 639 642 PF00400 0.357
TRG_ER_diArg_1 702 704 PF00400 0.378
TRG_ER_diArg_1 961 963 PF00400 0.611
TRG_ER_diArg_1 979 981 PF00400 0.312
TRG_ER_diArg_1 997 999 PF00400 0.470
TRG_NES_CRM1_1 294 309 PF08389 0.348
TRG_NES_CRM1_1 82 94 PF08389 0.490
TRG_NLS_MonoExtC_3 637 642 PF00514 0.353
TRG_Pf-PMV_PEXEL_1 1076 1081 PF00026 0.561
TRG_Pf-PMV_PEXEL_1 1447 1451 PF00026 0.513
TRG_Pf-PMV_PEXEL_1 561 565 PF00026 0.261
TRG_Pf-PMV_PEXEL_1 642 647 PF00026 0.325

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P883 Leptomonas seymouri 49% 100%
A0A3S7XAH3 Leishmania donovani 84% 100%
A4HNV1 Leishmania braziliensis 64% 100%
A4ICP3 Leishmania infantum 84% 100%
Q4Q1Y5 Leishmania major 81% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS