Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9ASJ9_LEIMU

TriTrypDb:

LmxM.36.0790

Length:

560

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASJ9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASJ9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	123	127	PF00656	0.660
CLV_C14_Caspase3-7	489	493	PF00656	0.653
CLV_NRD_NRD_1	134	136	PF00675	0.619
CLV_NRD_NRD_1	262	264	PF00675	0.708
CLV_NRD_NRD_1	289	291	PF00675	0.686
CLV_NRD_NRD_1	304	306	PF00675	0.571
CLV_NRD_NRD_1	310	312	PF00675	0.548
CLV_NRD_NRD_1	342	344	PF00675	0.704
CLV_NRD_NRD_1	347	349	PF00675	0.687
CLV_NRD_NRD_1	361	363	PF00675	0.633
CLV_NRD_NRD_1	411	413	PF00675	0.827
CLV_NRD_NRD_1	434	436	PF00675	0.656
CLV_NRD_NRD_1	60	62	PF00675	0.762
CLV_PCSK_FUR_1	260	264	PF00082	0.519
CLV_PCSK_KEX2_1	134	136	PF00082	0.619
CLV_PCSK_KEX2_1	243	245	PF00082	0.682
CLV_PCSK_KEX2_1	262	264	PF00082	0.707
CLV_PCSK_KEX2_1	289	291	PF00082	0.686
CLV_PCSK_KEX2_1	304	306	PF00082	0.777
CLV_PCSK_KEX2_1	310	312	PF00082	0.692
CLV_PCSK_KEX2_1	342	344	PF00082	0.698
CLV_PCSK_KEX2_1	347	349	PF00082	0.682
CLV_PCSK_KEX2_1	361	363	PF00082	0.645
CLV_PCSK_KEX2_1	434	436	PF00082	0.656
CLV_PCSK_KEX2_1	60	62	PF00082	0.762
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.791
CLV_PCSK_PC7_1	343	349	PF00082	0.769
CLV_PCSK_SKI1_1	207	211	PF00082	0.657
CLV_PCSK_SKI1_1	292	296	PF00082	0.732
CLV_PCSK_SKI1_1	387	391	PF00082	0.604
CLV_PCSK_SKI1_1	434	438	PF00082	0.628
DEG_APCC_DBOX_1	211	219	PF00400	0.663
DEG_APCC_DBOX_1	386	394	PF00400	0.727
DEG_Nend_UBRbox_2	1	3	PF02207	0.820
DEG_SPOP_SBC_1	297	301	PF00917	0.762
DEG_SPOP_SBC_1	396	400	PF00917	0.691
DOC_ANK_TNKS_1	487	494	PF00023	0.571
DOC_CKS1_1	50	55	PF01111	0.842
DOC_CYCLIN_yCln2_LP_2	478	484	PF00134	0.667
DOC_MAPK_DCC_7	3	12	PF00069	0.749
DOC_MAPK_gen_1	3	12	PF00069	0.749
DOC_MAPK_gen_1	310	316	PF00069	0.551
DOC_MAPK_MEF2A_6	3	12	PF00069	0.831
DOC_MAPK_MEF2A_6	505	514	PF00069	0.737
DOC_PP4_FxxP_1	360	363	PF00568	0.853
DOC_USP7_MATH_1	105	109	PF00917	0.703
DOC_USP7_MATH_1	179	183	PF00917	0.667
DOC_USP7_MATH_1	297	301	PF00917	0.684
DOC_USP7_MATH_1	396	400	PF00917	0.797
DOC_USP7_MATH_1	430	434	PF00917	0.559
DOC_USP7_MATH_1	503	507	PF00917	0.767
DOC_USP7_MATH_1	516	520	PF00917	0.783
DOC_USP7_MATH_1	83	87	PF00917	0.854
DOC_WW_Pin1_4	282	287	PF00397	0.821
DOC_WW_Pin1_4	305	310	PF00397	0.681
DOC_WW_Pin1_4	335	340	PF00397	0.659
DOC_WW_Pin1_4	349	354	PF00397	0.546
DOC_WW_Pin1_4	367	372	PF00397	0.718
DOC_WW_Pin1_4	37	42	PF00397	0.697
DOC_WW_Pin1_4	399	404	PF00397	0.729
DOC_WW_Pin1_4	428	433	PF00397	0.743
DOC_WW_Pin1_4	477	482	PF00397	0.831
DOC_WW_Pin1_4	49	54	PF00397	0.670
DOC_WW_Pin1_4	530	535	PF00397	0.509
DOC_WW_Pin1_4	69	74	PF00397	0.522
DOC_WW_Pin1_4	93	98	PF00397	0.590
LIG_14-3-3_CanoR_1	14	19	PF00244	0.827
LIG_14-3-3_CanoR_1	310	315	PF00244	0.553
LIG_14-3-3_CanoR_1	36	44	PF00244	0.644
LIG_14-3-3_CanoR_1	365	374	PF00244	0.582
LIG_14-3-3_CanoR_1	397	403	PF00244	0.800
LIG_14-3-3_CanoR_1	505	514	PF00244	0.552
LIG_14-3-3_CanoR_1	515	523	PF00244	0.739
LIG_BIR_III_2	94	98	PF00653	0.567
LIG_BIR_III_4	126	130	PF00653	0.636
LIG_BIR_III_4	161	165	PF00653	0.557
LIG_BRCT_BRCA1_1	274	278	PF00533	0.525
LIG_deltaCOP1_diTrp_1	540	546	PF00928	0.693
LIG_FHA_1	316	322	PF00498	0.532
LIG_FHA_1	389	395	PF00498	0.741
LIG_FHA_1	499	505	PF00498	0.761
LIG_FHA_2	143	149	PF00498	0.461
LIG_LIR_Apic_2	281	286	PF02991	0.533
LIG_LIR_Gen_1	186	191	PF02991	0.685
LIG_LIR_Gen_1	506	514	PF02991	0.684
LIG_LIR_Nem_3	153	158	PF02991	0.615
LIG_LIR_Nem_3	186	190	PF02991	0.692
LIG_LIR_Nem_3	25	31	PF02991	0.673
LIG_NRBOX	389	395	PF00104	0.655
LIG_Pex14_2	12	16	PF04695	0.832
LIG_PTB_Apo_2	181	188	PF02174	0.589
LIG_PTB_Phospho_1	181	187	PF10480	0.592
LIG_RPA_C_Fungi	219	231	PF08784	0.535
LIG_SH2_CRK	155	159	PF00017	0.641
LIG_SH2_STAP1	187	191	PF00017	0.699
LIG_SH2_STAP1	382	386	PF00017	0.646
LIG_SH2_STAT5	298	301	PF00017	0.848
LIG_SH3_2	371	376	PF14604	0.743
LIG_SH3_2	55	60	PF14604	0.630
LIG_SH3_3	368	374	PF00018	0.697
LIG_SH3_3	47	53	PF00018	0.852
LIG_SH3_3	478	484	PF00018	0.611
LIG_SH3_3	547	553	PF00018	0.753
LIG_SH3_3	67	73	PF00018	0.530
LIG_SH3_5	29	33	PF00018	0.553
LIG_SUMO_SIM_par_1	324	333	PF11976	0.522
LIG_TRAF2_1	146	149	PF00917	0.531
LIG_TRAF2_1	484	487	PF00917	0.644
LIG_TRAF2_2	484	489	PF00917	0.565
LIG_WRC_WIRS_1	504	509	PF05994	0.707
MOD_CDC14_SPxK_1	308	311	PF00782	0.553
MOD_CDC14_SPxK_1	370	373	PF00782	0.752
MOD_CDC14_SPxK_1	402	405	PF00782	0.740
MOD_CDC14_SPxK_1	431	434	PF00782	0.731
MOD_CDC14_SPxK_1	54	57	PF00782	0.854
MOD_CDK_SPK_2	305	310	PF00069	0.764
MOD_CDK_SPxK_1	305	311	PF00069	0.559
MOD_CDK_SPxK_1	367	373	PF00069	0.755
MOD_CDK_SPxK_1	399	405	PF00069	0.733
MOD_CDK_SPxK_1	428	434	PF00069	0.740
MOD_CDK_SPxK_1	51	57	PF00069	0.854
MOD_CDK_SPxxK_3	282	289	PF00069	0.535
MOD_CDK_SPxxK_3	335	342	PF00069	0.549
MOD_CDK_SPxxK_3	39	46	PF00069	0.774
MOD_CDK_SPxxK_3	428	435	PF00069	0.738
MOD_CK1_1	172	178	PF00069	0.795
MOD_CK1_1	21	27	PF00069	0.678
MOD_CK1_1	242	248	PF00069	0.670
MOD_CK1_1	271	277	PF00069	0.682
MOD_CK1_1	315	321	PF00069	0.688
MOD_CK1_1	324	330	PF00069	0.619
MOD_CK1_1	333	339	PF00069	0.613
MOD_CK1_1	35	41	PF00069	0.702
MOD_CK1_1	367	373	PF00069	0.755
MOD_CK1_1	395	401	PF00069	0.789
MOD_CK1_1	42	48	PF00069	0.776
MOD_CK1_1	530	536	PF00069	0.535
MOD_CK1_1	79	85	PF00069	0.782
MOD_CK2_1	142	148	PF00069	0.461
MOD_CK2_1	446	452	PF00069	0.693
MOD_CMANNOS	543	546	PF00535	0.773
MOD_Cter_Amidation	345	348	PF01082	0.773
MOD_Cter_Amidation	58	61	PF01082	0.758
MOD_GlcNHglycan	108	111	PF01048	0.751
MOD_GlcNHglycan	122	125	PF01048	0.589
MOD_GlcNHglycan	20	23	PF01048	0.729
MOD_GlcNHglycan	274	277	PF01048	0.570
MOD_GlcNHglycan	301	304	PF01048	0.850
MOD_GlcNHglycan	332	335	PF01048	0.700
MOD_GlcNHglycan	344	347	PF01048	0.754
MOD_GlcNHglycan	394	397	PF01048	0.716
MOD_GlcNHglycan	408	411	PF01048	0.609
MOD_GlcNHglycan	442	445	PF01048	0.792
MOD_GlcNHglycan	507	510	PF01048	0.629
MOD_GlcNHglycan	522	526	PF01048	0.677
MOD_GlcNHglycan	556	559	PF01048	0.827
MOD_GlcNHglycan	80	84	PF01048	0.774
MOD_GlcNHglycan	85	88	PF01048	0.712
MOD_GSK3_1	14	21	PF00069	0.827
MOD_GSK3_1	169	176	PF00069	0.781
MOD_GSK3_1	179	186	PF00069	0.588
MOD_GSK3_1	242	249	PF00069	0.690
MOD_GSK3_1	263	270	PF00069	0.725
MOD_GSK3_1	272	279	PF00069	0.668
MOD_GSK3_1	284	291	PF00069	0.654
MOD_GSK3_1	292	299	PF00069	0.699
MOD_GSK3_1	305	312	PF00069	0.738
MOD_GSK3_1	329	336	PF00069	0.714
MOD_GSK3_1	35	42	PF00069	0.782
MOD_GSK3_1	388	395	PF00069	0.635
MOD_GSK3_1	397	404	PF00069	0.625
MOD_GSK3_1	424	431	PF00069	0.769
MOD_GSK3_1	436	443	PF00069	0.608
MOD_GSK3_1	473	480	PF00069	0.810
MOD_GSK3_1	514	521	PF00069	0.530
MOD_GSK3_1	79	86	PF00069	0.853
MOD_GSK3_1	93	100	PF00069	0.626
MOD_LATS_1	261	267	PF00433	0.730
MOD_NEK2_1	140	145	PF00069	0.483
MOD_NEK2_1	169	174	PF00069	0.751
MOD_NEK2_1	514	519	PF00069	0.607
MOD_PIKK_1	365	371	PF00454	0.562
MOD_PIKK_1	44	50	PF00454	0.770
MOD_PK_1	290	296	PF00069	0.670
MOD_PK_1	310	316	PF00069	0.551
MOD_PKA_1	262	268	PF00069	0.687
MOD_PKA_1	310	316	PF00069	0.551
MOD_PKA_1	342	348	PF00069	0.604
MOD_PKA_2	261	267	PF00069	0.747
MOD_PKA_2	272	278	PF00069	0.596
MOD_PKA_2	288	294	PF00069	0.544
MOD_PKA_2	309	315	PF00069	0.634
MOD_PKA_2	342	348	PF00069	0.678
MOD_PKA_2	35	41	PF00069	0.740
MOD_PKA_2	364	370	PF00069	0.674
MOD_PKA_2	396	402	PF00069	0.796
MOD_PKA_2	459	465	PF00069	0.635
MOD_PKA_2	473	479	PF00069	0.679
MOD_PKA_2	514	520	PF00069	0.680
MOD_PKB_1	260	268	PF00069	0.604
MOD_PKB_1	290	298	PF00069	0.672
MOD_Plk_1	324	330	PF00069	0.721
MOD_Plk_1	79	85	PF00069	0.794
MOD_Plk_4	128	134	PF00069	0.697
MOD_Plk_4	173	179	PF00069	0.798
MOD_Plk_4	324	330	PF00069	0.721
MOD_Plk_4	388	394	PF00069	0.732
MOD_ProDKin_1	282	288	PF00069	0.822
MOD_ProDKin_1	305	311	PF00069	0.681
MOD_ProDKin_1	335	341	PF00069	0.661
MOD_ProDKin_1	349	355	PF00069	0.547
MOD_ProDKin_1	367	373	PF00069	0.718
MOD_ProDKin_1	37	43	PF00069	0.695
MOD_ProDKin_1	399	405	PF00069	0.733
MOD_ProDKin_1	428	434	PF00069	0.740
MOD_ProDKin_1	477	483	PF00069	0.830
MOD_ProDKin_1	49	55	PF00069	0.666
MOD_ProDKin_1	530	536	PF00069	0.504
MOD_ProDKin_1	69	75	PF00069	0.522
MOD_ProDKin_1	93	99	PF00069	0.593
MOD_SUMO_rev_2	123	132	PF00179	0.630
TRG_DiLeu_BaEn_1	206	211	PF01217	0.659
TRG_DiLeu_BaEn_1	385	390	PF01217	0.717
TRG_DiLeu_BaEn_4	453	459	PF01217	0.559
TRG_DiLeu_BaLyEn_6	474	479	PF01217	0.752
TRG_ENDOCYTIC_2	155	158	PF00928	0.704
TRG_ENDOCYTIC_2	187	190	PF00928	0.707
TRG_ER_diArg_1	133	135	PF00400	0.621
TRG_ER_diArg_1	211	214	PF00400	0.661
TRG_ER_diArg_1	260	263	PF00400	0.597
TRG_ER_diArg_1	288	290	PF00400	0.688
TRG_ER_diArg_1	309	311	PF00400	0.554
TRG_ER_diArg_1	360	362	PF00400	0.720
TRG_ER_diArg_1	434	436	PF00400	0.645
TRG_Pf-PMV_PEXEL_1	156	161	PF00026	0.611

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGY6	Leishmania donovani	78%	100%
A4HNT9	Leishmania braziliensis	55%	100%
A4ICQ5	Leishmania infantum	78%	100%
Q4Q1Z7	Leishmania major	79%	100%