C3H1-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ASJ4_LEIMU

TriTrypDb:

LmxM.36.0740

Length:

540

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 4
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASJ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASJ4

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	258	262	PF00656	0.613
CLV_C14_Caspase3-7	360	364	PF00656	0.438
CLV_C14_Caspase3-7	505	509	PF00656	0.487
CLV_NRD_NRD_1	469	471	PF00675	0.469
CLV_NRD_NRD_1	505	507	PF00675	0.464
CLV_PCSK_KEX2_1	471	473	PF00082	0.422
CLV_PCSK_PC1ET2_1	471	473	PF00082	0.422
CLV_PCSK_SKI1_1	274	278	PF00082	0.378
CLV_PCSK_SKI1_1	311	315	PF00082	0.548
DOC_CDC14_PxL_1	416	424	PF14671	0.409

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7W2	Leptomonas seymouri	69%	100%
A0A3S7XAD2	Leishmania donovani	93%	100%
A4HNT4	Leishmania braziliensis	85%	100%
A4ICR0	Leishmania infantum	93%	99%
Q4Q202	Leishmania major	94%	100%

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