Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ASI9_LEIMU

TriTrypDb:

LmxM.36.0690

Length:

268

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASI9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASI9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	209	211	PF00675	0.605
CLV_NRD_NRD_1	5	7	PF00675	0.529
CLV_NRD_NRD_1	51	53	PF00675	0.590
CLV_NRD_NRD_1	76	78	PF00675	0.549
CLV_PCSK_KEX2_1	132	134	PF00082	0.617
CLV_PCSK_KEX2_1	209	211	PF00082	0.611
CLV_PCSK_KEX2_1	5	7	PF00082	0.529
CLV_PCSK_KEX2_1	51	53	PF00082	0.590
CLV_PCSK_KEX2_1	75	77	PF00082	0.580
CLV_PCSK_PC1ET2_1	132	134	PF00082	0.653
CLV_PCSK_PC1ET2_1	75	77	PF00082	0.624
CLV_PCSK_SKI1_1	163	167	PF00082	0.528
CLV_PCSK_SKI1_1	209	213	PF00082	0.424
CLV_PCSK_SKI1_1	242	246	PF00082	0.562
CLV_PCSK_SKI1_1	27	31	PF00082	0.551
CLV_PCSK_SKI1_1	5	9	PF00082	0.550
CLV_PCSK_SKI1_1	85	89	PF00082	0.572
DEG_Nend_UBRbox_1	1	4	PF02207	0.651
DEG_SPOP_SBC_1	64	68	PF00917	0.556
DOC_CYCLIN_RxL_1	2	11	PF00134	0.480
DOC_MAPK_DCC_7	242	251	PF00069	0.439
DOC_MAPK_MEF2A_6	242	251	PF00069	0.439
DOC_USP7_MATH_1	122	126	PF00917	0.684
DOC_USP7_MATH_1	17	21	PF00917	0.677
DOC_USP7_MATH_1	180	184	PF00917	0.608
DOC_USP7_MATH_1	196	200	PF00917	0.775
DOC_USP7_MATH_1	22	26	PF00917	0.587
DOC_USP7_MATH_1	42	46	PF00917	0.559
DOC_USP7_MATH_1	65	69	PF00917	0.534
DOC_WW_Pin1_4	153	158	PF00397	0.460
DOC_WW_Pin1_4	164	169	PF00397	0.409
LIG_14-3-3_CanoR_1	51	56	PF00244	0.572
LIG_14-3-3_CanoR_1	62	71	PF00244	0.598
LIG_14-3-3_CanoR_1	85	93	PF00244	0.622
LIG_FHA_1	135	141	PF00498	0.565
LIG_FHA_1	225	231	PF00498	0.313
LIG_FHA_1	243	249	PF00498	0.450
LIG_FHA_1	52	58	PF00498	0.479
LIG_FHA_1	90	96	PF00498	0.529
LIG_HP1_1	22	26	PF01393	0.448
LIG_LIR_Nem_3	68	74	PF02991	0.549
LIG_MYND_3	246	250	PF01753	0.489
LIG_PCNA_yPIPBox_3	222	236	PF02747	0.421
LIG_PDZ_Class_3	263	268	PF00595	0.401
LIG_SH2_STAT5	108	111	PF00017	0.477
LIG_SH3_3	241	247	PF00018	0.476
LIG_SUMO_SIM_par_1	22	28	PF11976	0.550
LIG_SUMO_SIM_par_1	90	96	PF11976	0.524
MOD_CK1_1	153	159	PF00069	0.622
MOD_CK1_1	183	189	PF00069	0.619
MOD_CK1_1	200	206	PF00069	0.584
MOD_CK1_1	259	265	PF00069	0.356
MOD_CK1_1	45	51	PF00069	0.594
MOD_CK1_1	66	72	PF00069	0.602
MOD_CK2_1	22	28	PF00069	0.674
MOD_CK2_1	66	72	PF00069	0.567
MOD_Cter_Amidation	130	133	PF01082	0.610
MOD_GlcNHglycan	10	13	PF01048	0.600
MOD_GlcNHglycan	124	127	PF01048	0.575
MOD_GlcNHglycan	19	22	PF01048	0.658
MOD_GlcNHglycan	194	197	PF01048	0.522
MOD_GlcNHglycan	40	43	PF01048	0.760
MOD_GSK3_1	134	141	PF00069	0.530
MOD_GSK3_1	180	187	PF00069	0.655
MOD_GSK3_1	192	199	PF00069	0.600
MOD_GSK3_1	38	45	PF00069	0.637
MOD_GSK3_1	63	70	PF00069	0.595
MOD_GSK3_1	8	15	PF00069	0.682
MOD_GSK3_1	85	92	PF00069	0.532
MOD_N-GLC_1	12	17	PF02516	0.619
MOD_N-GLC_1	141	146	PF02516	0.494
MOD_NEK2_1	150	155	PF00069	0.533
MOD_NEK2_1	256	261	PF00069	0.493
MOD_NEK2_1	8	13	PF00069	0.644
MOD_NEK2_2	103	108	PF00069	0.419
MOD_NEK2_2	22	27	PF00069	0.582
MOD_PIKK_1	190	196	PF00454	0.574
MOD_PIKK_1	56	62	PF00454	0.474
MOD_PKA_1	51	57	PF00069	0.586
MOD_PKA_2	51	57	PF00069	0.586
MOD_Plk_1	27	33	PF00069	0.504
MOD_Plk_1	89	95	PF00069	0.489
MOD_Plk_4	103	109	PF00069	0.414
MOD_Plk_4	197	203	PF00069	0.580
MOD_Plk_4	45	51	PF00069	0.649
MOD_ProDKin_1	153	159	PF00069	0.461
MOD_ProDKin_1	164	170	PF00069	0.406
TRG_ER_diArg_1	208	210	PF00400	0.455
TRG_ER_diArg_1	5	7	PF00400	0.526
TRG_ER_diArg_1	50	52	PF00400	0.592
TRG_NES_CRM1_1	239	250	PF08389	0.466
TRG_Pf-PMV_PEXEL_1	261	266	PF00026	0.371
TRG_Pf-PMV_PEXEL_1	85	90	PF00026	0.571

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFQ8	Leptomonas seymouri	36%	89%
A0A3S7XAG1	Leishmania donovani	88%	100%
A4HNS9	Leishmania braziliensis	79%	100%
A4ICR5	Leishmania infantum	88%	100%
Q4Q207	Leishmania major	88%	100%