DNAJ protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DNAJ protein-like protein

Species:

Leishmania mexicana

UniProt:

E9ASI1_LEIMU

TriTrypDb:

LmxM.36.0610

Length:

260

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASI1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASI1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	231	233	PF00675	0.411
CLV_PCSK_KEX2_1	188	190	PF00082	0.389
CLV_PCSK_KEX2_1	231	233	PF00082	0.411
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.413
CLV_PCSK_SKI1_1	113	117	PF00082	0.654
CLV_PCSK_SKI1_1	193	197	PF00082	0.411
CLV_PCSK_SKI1_1	216	220	PF00082	0.411
CLV_PCSK_SKI1_1	49	53	PF00082	0.486
DEG_APCC_DBOX_1	146	154	PF00400	0.777
DEG_APCC_DBOX_1	162	170	PF00400	0.491
DOC_CYCLIN_RxL_1	188	201	PF00134	0.411
DOC_MAPK_gen_1	161	169	PF00069	0.584
DOC_MAPK_gen_1	188	198	PF00069	0.408
DOC_PP4_FxxP_1	68	71	PF00568	0.663
DOC_USP7_MATH_1	180	184	PF00917	0.355
DOC_USP7_MATH_1	32	36	PF00917	0.665
DOC_USP7_MATH_1	58	62	PF00917	0.759
DOC_USP7_UBL2_3	157	161	PF12436	0.605
DOC_USP7_UBL2_3	188	192	PF12436	0.513
DOC_USP7_UBL2_3	216	220	PF12436	0.411
DOC_WW_Pin1_4	49	54	PF00397	0.723
LIG_APCC_ABBA_1	196	201	PF00400	0.411
LIG_BRCT_BRCA1_1	34	38	PF00533	0.465
LIG_FHA_1	46	52	PF00498	0.563
LIG_FHA_2	179	185	PF00498	0.411
LIG_FHA_2	206	212	PF00498	0.383
LIG_FHA_2	224	230	PF00498	0.246
LIG_LIR_Apic_2	66	71	PF02991	0.666
LIG_LIR_Gen_1	17	28	PF02991	0.534
LIG_LIR_Nem_3	17	23	PF02991	0.625
LIG_LIR_Nem_3	213	218	PF02991	0.355
LIG_LIR_Nem_3	35	41	PF02991	0.627
LIG_PTB_Apo_2	62	69	PF02174	0.663
LIG_Rb_pABgroove_1	103	111	PF01858	0.752
LIG_SH2_CRK	173	177	PF00017	0.411
LIG_SH2_NCK_1	120	124	PF00017	0.618
LIG_SH2_SRC	93	96	PF00017	0.650
LIG_SH2_STAP1	234	238	PF00017	0.554
LIG_SH2_STAT5	40	43	PF00017	0.570
LIG_SH2_STAT5	93	96	PF00017	0.672
LIG_TRAF2_1	182	185	PF00917	0.411
LIG_TRAF2_1	208	211	PF00917	0.383
LIG_UBA3_1	108	116	PF00899	0.647
LIG_UBA3_1	214	220	PF00899	0.411
MOD_CK1_1	237	243	PF00069	0.679
MOD_CK1_1	26	32	PF00069	0.595
MOD_CK1_1	43	49	PF00069	0.728
MOD_CK1_1	76	82	PF00069	0.653
MOD_CK1_1	8	14	PF00069	0.750
MOD_CK2_1	122	128	PF00069	0.714
MOD_CK2_1	178	184	PF00069	0.411
MOD_CK2_1	205	211	PF00069	0.383
MOD_CK2_1	223	229	PF00069	0.378
MOD_CK2_1	81	87	PF00069	0.738
MOD_Cter_Amidation	133	136	PF01082	0.684
MOD_GlcNHglycan	136	139	PF01048	0.690
MOD_GlcNHglycan	239	242	PF01048	0.664
MOD_GlcNHglycan	249	252	PF01048	0.576
MOD_GlcNHglycan	25	28	PF01048	0.654
MOD_GlcNHglycan	29	32	PF01048	0.661
MOD_GlcNHglycan	34	37	PF01048	0.650
MOD_GlcNHglycan	45	48	PF01048	0.449
MOD_GlcNHglycan	68	71	PF01048	0.663
MOD_GlcNHglycan	83	86	PF01048	0.636
MOD_GlcNHglycan	97	100	PF01048	0.663
MOD_GSK3_1	19	26	PF00069	0.681
MOD_GSK3_1	253	260	PF00069	0.563
MOD_GSK3_1	39	46	PF00069	0.659
MOD_GSK3_1	7	14	PF00069	0.655
MOD_GSK3_1	72	79	PF00069	0.651
MOD_GSK3_1	81	88	PF00069	0.706
MOD_N-GLC_1	151	156	PF02516	0.543
MOD_N-GLC_1	23	28	PF02516	0.654
MOD_N-GLC_1	49	54	PF02516	0.703
MOD_N-GLC_1	6	11	PF02516	0.761
MOD_NEK2_1	109	114	PF00069	0.644
MOD_NEK2_1	19	24	PF00069	0.653
MOD_NEK2_1	39	44	PF00069	0.666
MOD_PIKK_1	205	211	PF00454	0.347
MOD_PKA_2	146	152	PF00069	0.674
MOD_Plk_1	11	17	PF00069	0.561
MOD_Plk_1	234	240	PF00069	0.556
MOD_Plk_2-3	223	229	PF00069	0.411
MOD_Plk_4	11	17	PF00069	0.619
MOD_Plk_4	122	128	PF00069	0.612
MOD_Plk_4	59	65	PF00069	0.644
MOD_ProDKin_1	49	55	PF00069	0.725
MOD_SUMO_rev_2	158	162	PF00179	0.545
MOD_SUMO_rev_2	183	190	PF00179	0.513
TRG_DiLeu_BaLyEn_6	162	167	PF01217	0.578
TRG_ENDOCYTIC_2	172	175	PF00928	0.411
TRG_ER_diArg_1	162	165	PF00400	0.588
TRG_ER_diArg_1	231	233	PF00400	0.513
TRG_NLS_MonoExtN_4	189	196	PF00514	0.389

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7W1	Leptomonas seymouri	59%	85%
A0A3Q8IQI1	Leishmania donovani	88%	100%
A4HNS1	Leishmania braziliensis	71%	100%
A4ICS3	Leishmania infantum	88%	100%
Q4Q215	Leishmania major	84%	100%