Zinc-finger of a C2HC-type family protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

zinc-finger of a C2HC-type, putative

Species:

Leishmania mexicana

UniProt:

E9ASG6_LEIMU

TriTrypDb:

LmxM.36.0490

Length:

348

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASG6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASG6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	301	305	PF00656	0.612
CLV_NRD_NRD_1	128	130	PF00675	0.573
CLV_NRD_NRD_1	159	161	PF00675	0.758
CLV_NRD_NRD_1	200	202	PF00675	0.391
CLV_PCSK_KEX2_1	127	129	PF00082	0.576
CLV_PCSK_KEX2_1	159	161	PF00082	0.677
CLV_PCSK_KEX2_1	200	202	PF00082	0.560
CLV_PCSK_KEX2_1	253	255	PF00082	0.753
CLV_PCSK_KEX2_1	34	36	PF00082	0.493
CLV_PCSK_PC1ET2_1	127	129	PF00082	0.553
CLV_PCSK_PC1ET2_1	253	255	PF00082	0.539
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.493
CLV_PCSK_SKI1_1	128	132	PF00082	0.638
CLV_PCSK_SKI1_1	31	35	PF00082	0.469
CLV_PCSK_SKI1_1	81	85	PF00082	0.559
DEG_SPOP_SBC_1	169	173	PF00917	0.706
DOC_PP4_FxxP_1	152	155	PF00568	0.778
DOC_USP7_MATH_1	195	199	PF00917	0.512
DOC_USP7_MATH_1	215	219	PF00917	0.431
DOC_USP7_MATH_1	233	237	PF00917	0.728
DOC_USP7_MATH_1	242	246	PF00917	0.754
DOC_USP7_MATH_1	75	79	PF00917	0.725
DOC_USP7_UBL2_3	123	127	PF12436	0.516
DOC_USP7_UBL2_3	53	57	PF12436	0.785
DOC_WW_Pin1_4	173	178	PF00397	0.705
DOC_WW_Pin1_4	295	300	PF00397	0.704
LIG_14-3-3_CanoR_1	247	257	PF00244	0.759
LIG_BRCT_BRCA1_1	244	248	PF00533	0.480
LIG_BRCT_BRCA1_1	309	313	PF00533	0.625
LIG_FHA_1	161	167	PF00498	0.703
LIG_FHA_1	250	256	PF00498	0.752
LIG_FHA_1	334	340	PF00498	0.589
LIG_FHA_1	6	12	PF00498	0.369
LIG_LIR_Apic_2	151	155	PF02991	0.485
LIG_LIR_Gen_1	109	117	PF02991	0.444
LIG_LIR_Nem_3	109	115	PF02991	0.444
LIG_SH2_NCK_1	175	179	PF00017	0.698
LIG_SH2_STAT5	175	178	PF00017	0.656
LIG_SH3_3	211	217	PF00018	0.694
LIG_SH3_3	291	297	PF00018	0.795
LIG_SH3_3	37	43	PF00018	0.552
LIG_SH3_3	69	75	PF00018	0.653
LIG_SH3_4	53	60	PF00018	0.707
MOD_CK1_1	173	179	PF00069	0.665
MOD_CK1_1	218	224	PF00069	0.572
MOD_CK1_1	249	255	PF00069	0.748
MOD_CK1_1	307	313	PF00069	0.597
MOD_GlcNHglycan	155	158	PF01048	0.677
MOD_GlcNHglycan	17	20	PF01048	0.427
MOD_GlcNHglycan	197	200	PF01048	0.562
MOD_GlcNHglycan	235	238	PF01048	0.733
MOD_GlcNHglycan	244	247	PF01048	0.760
MOD_GlcNHglycan	248	251	PF01048	0.733
MOD_GlcNHglycan	300	303	PF01048	0.611
MOD_GlcNHglycan	306	309	PF01048	0.589
MOD_GlcNHglycan	63	66	PF01048	0.690
MOD_GlcNHglycan	77	80	PF01048	0.604
MOD_GSK3_1	165	172	PF00069	0.692
MOD_GSK3_1	191	198	PF00069	0.485
MOD_GSK3_1	215	222	PF00069	0.685
MOD_GSK3_1	242	249	PF00069	0.768
MOD_GSK3_1	298	305	PF00069	0.700
MOD_GSK3_1	307	314	PF00069	0.655
MOD_GSK3_1	75	82	PF00069	0.702
MOD_N-GLC_1	169	174	PF02516	0.722
MOD_N-GLC_1	262	267	PF02516	0.648
MOD_N-GLC_1	334	339	PF02516	0.602
MOD_NEK2_1	131	136	PF00069	0.556
MOD_NEK2_1	209	214	PF00069	0.686
MOD_NEK2_1	231	236	PF00069	0.717
MOD_NEK2_1	248	253	PF00069	0.445
MOD_NEK2_2	79	84	PF00069	0.516
MOD_PKA_2	246	252	PF00069	0.770
MOD_PKA_2	302	308	PF00069	0.677
MOD_PKA_2	311	317	PF00069	0.651
MOD_Plk_1	262	268	PF00069	0.648
MOD_Plk_1	334	340	PF00069	0.602
MOD_ProDKin_1	173	179	PF00069	0.704
MOD_ProDKin_1	295	301	PF00069	0.706
TRG_ER_diArg_1	128	130	PF00400	0.642
TRG_ER_diArg_1	159	162	PF00400	0.700
TRG_ER_FFAT_2	190	198	PF00635	0.343
TRG_NLS_MonoExtC_3	126	132	PF00514	0.540
TRG_Pf-PMV_PEXEL_1	330	334	PF00026	0.705
TRG_Pf-PMV_PEXEL_1	81	86	PF00026	0.624

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HYW4	Leptomonas seymouri	57%	94%
A0A1X0P958	Trypanosomatidae	41%	100%
A0A3R7MA87	Trypanosoma rangeli	42%	100%
A0A3S7XAD7	Leishmania donovani	91%	100%
A4HNQ7	Leishmania braziliensis	76%	98%
A4ICT8	Leishmania infantum	91%	100%
Q4Q229	Leishmania major	92%	100%
V5BQI1	Trypanosoma cruzi	41%	100%