Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ASG2_LEIMU

TriTrypDb:

LmxM.36.0450

Length:

527

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASG2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASG2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	172	176	PF00656	0.681
CLV_C14_Caspase3-7	309	313	PF00656	0.666
CLV_C14_Caspase3-7	507	511	PF00656	0.570
CLV_NRD_NRD_1	278	280	PF00675	0.666
CLV_NRD_NRD_1	378	380	PF00675	0.626
CLV_PCSK_KEX2_1	278	280	PF00082	0.666
CLV_PCSK_KEX2_1	378	380	PF00082	0.626
CLV_PCSK_SKI1_1	123	127	PF00082	0.603
CLV_PCSK_SKI1_1	448	452	PF00082	0.639
CLV_PCSK_SKI1_1	81	85	PF00082	0.425
DEG_APCC_DBOX_1	80	88	PF00400	0.422
DEG_SPOP_SBC_1	235	239	PF00917	0.607
DEG_SPOP_SBC_1	27	31	PF00917	0.588
DEG_SPOP_SBC_1	294	298	PF00917	0.678
DEG_SPOP_SBC_1	431	435	PF00917	0.647
DOC_CYCLIN_yCln2_LP_2	366	372	PF00134	0.497
DOC_MAPK_gen_1	78	86	PF00069	0.493
DOC_MAPK_MEF2A_6	78	86	PF00069	0.493
DOC_PP2B_LxvP_1	366	369	PF13499	0.491
DOC_USP7_MATH_1	142	146	PF00917	0.641
DOC_USP7_MATH_1	198	202	PF00917	0.601
DOC_USP7_MATH_1	204	208	PF00917	0.612
DOC_USP7_MATH_1	234	238	PF00917	0.610
DOC_USP7_MATH_1	28	32	PF00917	0.598
DOC_USP7_MATH_1	288	292	PF00917	0.534
DOC_USP7_MATH_1	320	324	PF00917	0.664
DOC_USP7_MATH_1	360	364	PF00917	0.669
DOC_USP7_MATH_1	402	406	PF00917	0.581
DOC_USP7_MATH_1	409	413	PF00917	0.644
DOC_USP7_MATH_1	430	434	PF00917	0.713
DOC_USP7_MATH_1	437	441	PF00917	0.573
DOC_USP7_MATH_1	464	468	PF00917	0.621
DOC_USP7_MATH_1	500	504	PF00917	0.650
DOC_WW_Pin1_4	165	170	PF00397	0.649
DOC_WW_Pin1_4	213	218	PF00397	0.614
DOC_WW_Pin1_4	349	354	PF00397	0.660
DOC_WW_Pin1_4	361	366	PF00397	0.644
DOC_WW_Pin1_4	66	71	PF00397	0.650
LIG_14-3-3_CanoR_1	111	116	PF00244	0.432
LIG_14-3-3_CanoR_1	144	152	PF00244	0.625
LIG_14-3-3_CanoR_1	16	22	PF00244	0.490
LIG_14-3-3_CanoR_1	268	276	PF00244	0.622
LIG_14-3-3_CanoR_1	42	46	PF00244	0.518
LIG_14-3-3_CanoR_1	463	471	PF00244	0.634
LIG_14-3-3_CanoR_1	62	70	PF00244	0.542
LIG_BIR_III_4	444	448	PF00653	0.647
LIG_DLG_GKlike_1	111	118	PF00625	0.501
LIG_FHA_1	120	126	PF00498	0.569
LIG_FHA_1	129	135	PF00498	0.586
LIG_FHA_1	27	33	PF00498	0.591
LIG_FHA_1	271	277	PF00498	0.623
LIG_FHA_1	451	457	PF00498	0.771
LIG_FHA_2	327	333	PF00498	0.689
LIG_FHA_2	452	458	PF00498	0.623
LIG_FHA_2	75	81	PF00498	0.505
LIG_FHA_2	98	104	PF00498	0.423
LIG_LIR_Nem_3	150	155	PF02991	0.624
LIG_LIR_Nem_3	509	515	PF02991	0.580
LIG_NRBOX	82	88	PF00104	0.420
LIG_SH2_CRK	152	156	PF00017	0.616
LIG_SH2_STAP1	515	519	PF00017	0.470
LIG_SH2_STAT3	189	192	PF00017	0.670
LIG_SH2_STAT3	88	91	PF00017	0.419
LIG_SH2_STAT5	39	42	PF00017	0.692
LIG_SH3_1	378	384	PF00018	0.614
LIG_SH3_3	246	252	PF00018	0.609
LIG_SH3_3	347	353	PF00018	0.681
LIG_SH3_3	370	376	PF00018	0.603
LIG_SH3_3	378	384	PF00018	0.554
LIG_SH3_3	9	15	PF00018	0.693
MOD_CK1_1	119	125	PF00069	0.516
MOD_CK1_1	132	138	PF00069	0.603
MOD_CK1_1	143	149	PF00069	0.602
MOD_CK1_1	17	23	PF00069	0.659
MOD_CK1_1	187	193	PF00069	0.555
MOD_CK1_1	219	225	PF00069	0.633
MOD_CK1_1	241	247	PF00069	0.656
MOD_CK1_1	256	262	PF00069	0.666
MOD_CK1_1	26	32	PF00069	0.646
MOD_CK1_1	267	273	PF00069	0.616
MOD_CK1_1	286	292	PF00069	0.618
MOD_CK1_1	314	320	PF00069	0.757
MOD_CK1_1	323	329	PF00069	0.618
MOD_CK1_1	330	336	PF00069	0.631
MOD_CK1_1	352	358	PF00069	0.633
MOD_CK1_1	37	43	PF00069	0.564
MOD_CK1_1	400	406	PF00069	0.648
MOD_CK1_1	411	417	PF00069	0.574
MOD_CK1_1	435	441	PF00069	0.680
MOD_CK1_1	514	520	PF00069	0.475
MOD_CK1_1	65	71	PF00069	0.650
MOD_CK2_1	144	150	PF00069	0.677
MOD_CK2_1	204	210	PF00069	0.604
MOD_CK2_1	419	425	PF00069	0.636
MOD_CK2_1	451	457	PF00069	0.623
MOD_CK2_1	5	11	PF00069	0.636
MOD_CK2_1	66	72	PF00069	0.649
MOD_CK2_1	97	103	PF00069	0.425
MOD_Cter_Amidation	276	279	PF01082	0.616
MOD_DYRK1A_RPxSP_1	213	217	PF00069	0.592
MOD_GlcNHglycan	136	139	PF01048	0.731
MOD_GlcNHglycan	146	149	PF01048	0.601
MOD_GlcNHglycan	16	19	PF01048	0.672
MOD_GlcNHglycan	171	174	PF01048	0.633
MOD_GlcNHglycan	182	185	PF01048	0.591
MOD_GlcNHglycan	189	192	PF01048	0.731
MOD_GlcNHglycan	200	203	PF01048	0.514
MOD_GlcNHglycan	232	235	PF01048	0.612
MOD_GlcNHglycan	243	246	PF01048	0.639
MOD_GlcNHglycan	258	261	PF01048	0.633
MOD_GlcNHglycan	273	276	PF01048	0.535
MOD_GlcNHglycan	286	289	PF01048	0.616
MOD_GlcNHglycan	316	319	PF01048	0.622
MOD_GlcNHglycan	325	328	PF01048	0.658
MOD_GlcNHglycan	411	414	PF01048	0.677
MOD_GlcNHglycan	421	424	PF01048	0.639
MOD_GlcNHglycan	45	48	PF01048	0.587
MOD_GlcNHglycan	466	469	PF01048	0.604
MOD_GlcNHglycan	500	503	PF01048	0.655
MOD_GlcNHglycan	64	67	PF01048	0.489
MOD_GlcNHglycan	7	10	PF01048	0.612
MOD_GSK3_1	119	126	PF00069	0.515
MOD_GSK3_1	128	135	PF00069	0.608
MOD_GSK3_1	140	147	PF00069	0.647
MOD_GSK3_1	165	172	PF00069	0.597
MOD_GSK3_1	180	187	PF00069	0.492
MOD_GSK3_1	204	211	PF00069	0.673
MOD_GSK3_1	219	226	PF00069	0.644
MOD_GSK3_1	23	30	PF00069	0.636
MOD_GSK3_1	230	237	PF00069	0.611
MOD_GSK3_1	252	259	PF00069	0.629
MOD_GSK3_1	264	271	PF00069	0.618
MOD_GSK3_1	282	289	PF00069	0.615
MOD_GSK3_1	316	323	PF00069	0.802
MOD_GSK3_1	326	333	PF00069	0.628
MOD_GSK3_1	37	44	PF00069	0.512
MOD_GSK3_1	382	389	PF00069	0.556
MOD_GSK3_1	398	405	PF00069	0.637
MOD_GSK3_1	411	418	PF00069	0.649
MOD_GSK3_1	431	438	PF00069	0.634
MOD_GSK3_1	462	469	PF00069	0.531
MOD_GSK3_1	494	501	PF00069	0.631
MOD_GSK3_1	58	65	PF00069	0.624
MOD_LATS_1	121	127	PF00433	0.556
MOD_LATS_1	266	272	PF00433	0.618
MOD_N-GLC_1	132	137	PF02516	0.504
MOD_N-GLC_1	253	258	PF02516	0.616
MOD_NEK2_1	128	133	PF00069	0.611
MOD_NEK2_1	134	139	PF00069	0.737
MOD_NEK2_1	164	169	PF00069	0.649
MOD_NEK2_1	209	214	PF00069	0.587
MOD_NEK2_1	283	288	PF00069	0.615
MOD_NEK2_1	311	316	PF00069	0.667
MOD_NEK2_1	35	40	PF00069	0.570
MOD_NEK2_1	419	424	PF00069	0.636
MOD_NEK2_1	436	441	PF00069	0.835
MOD_PIKK_1	330	336	PF00454	0.692
MOD_PKA_2	116	122	PF00069	0.467
MOD_PKA_2	143	149	PF00069	0.562
MOD_PKA_2	267	273	PF00069	0.623
MOD_PKA_2	386	392	PF00069	0.566
MOD_PKA_2	41	47	PF00069	0.583
MOD_PKA_2	462	468	PF00069	0.769
MOD_PKB_1	446	454	PF00069	0.687
MOD_Plk_1	253	259	PF00069	0.679
MOD_Plk_1	311	317	PF00069	0.670
MOD_Plk_1	415	421	PF00069	0.651
MOD_Plk_1	504	510	PF00069	0.572
MOD_Plk_4	184	190	PF00069	0.671
MOD_Plk_4	204	210	PF00069	0.485
MOD_ProDKin_1	165	171	PF00069	0.654
MOD_ProDKin_1	213	219	PF00069	0.616
MOD_ProDKin_1	349	355	PF00069	0.661
MOD_ProDKin_1	361	367	PF00069	0.644
MOD_ProDKin_1	66	72	PF00069	0.649
MOD_SUMO_rev_2	298	308	PF00179	0.754
TRG_DiLeu_BaEn_1	79	84	PF01217	0.426
TRG_DiLeu_BaLyEn_6	279	284	PF01217	0.611
TRG_DiLeu_BaLyEn_6	82	87	PF01217	0.421
TRG_ENDOCYTIC_2	152	155	PF00928	0.581
TRG_ENDOCYTIC_2	377	380	PF00928	0.652
TRG_ER_diArg_1	377	379	PF00400	0.633
TRG_Pf-PMV_PEXEL_1	85	90	PF00026	0.420

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCL9	Leptomonas seymouri	49%	100%
A0A3Q8INA6	Leishmania donovani	91%	100%
A4HNQ3	Leishmania braziliensis	79%	100%
A4ICU2	Leishmania infantum	90%	100%