| Source | Evidence on protein | Close homologs |
|---|---|---|
| Cuervo et al. | no | yes: 0 |
| Hassani et al. | no | yes: 0 |
| Forrest at al. (metacyclic) | no | yes: 0 |
| Forrest at al. (procyclic) | no | yes: 6 |
| Silverman et al. | no | yes: 0 |
| Pissara et al. | yes | yes: 16 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Pires et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Silverman et al. | no | yes: 0 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| Jamdhade et al. | no | yes: 14 |
| Source | Evidence on protein | Close homologs |
|---|---|---|
| DeepLoc | ||
| SignalP6 | no | yes: 0, no: 11 |
| NetGPI | no | yes: 0, no: 11 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0005634 | nucleus | 5 | 12 |
| GO:0005737 | cytoplasm | 2 | 12 |
| GO:0005839 | proteasome core complex | 3 | 12 |
| GO:0032991 | protein-containing complex | 1 | 12 |
| GO:0043226 | organelle | 2 | 12 |
| GO:0043227 | membrane-bounded organelle | 3 | 12 |
| GO:0043229 | intracellular organelle | 3 | 12 |
| GO:0043231 | intracellular membrane-bounded organelle | 4 | 12 |
| GO:0110165 | cellular anatomical entity | 1 | 12 |
| GO:0140535 | intracellular protein-containing complex | 2 | 12 |
| GO:1902494 | catalytic complex | 2 | 12 |
| GO:0019774 | proteasome core complex, beta-subunit complex | 2 | 1 |
| GO:0016020 | membrane | 2 | 2 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0006508 | proteolysis | 4 | 12 |
| GO:0006807 | nitrogen compound metabolic process | 2 | 12 |
| GO:0008152 | metabolic process | 1 | 12 |
| GO:0009056 | catabolic process | 2 | 12 |
| GO:0009057 | macromolecule catabolic process | 4 | 12 |
| GO:0010498 | proteasomal protein catabolic process | 5 | 12 |
| GO:0019538 | protein metabolic process | 3 | 12 |
| GO:0030163 | protein catabolic process | 4 | 12 |
| GO:0043170 | macromolecule metabolic process | 3 | 12 |
| GO:0044238 | primary metabolic process | 2 | 12 |
| GO:0051603 | proteolysis involved in protein catabolic process | 5 | 12 |
| GO:0071704 | organic substance metabolic process | 2 | 12 |
| GO:1901564 | organonitrogen compound metabolic process | 3 | 12 |
| GO:1901565 | organonitrogen compound catabolic process | 4 | 12 |
| GO:1901575 | organic substance catabolic process | 3 | 12 |
| Term | Name | Level | Count |
|---|---|---|---|
| GO:0003824 | catalytic activity | 1 | 8 |
| GO:0016787 | hydrolase activity | 2 | 8 |
| Leishmania | From | To | Domain/Motif | Score |
|---|---|---|---|---|
| CLV_NRD_NRD_1 | 180 | 182 | PF00675 | 0.355 |
| CLV_PCSK_KEX2_1 | 179 | 181 | PF00082 | 0.294 |
| CLV_PCSK_PC1ET2_1 | 179 | 181 | PF00082 | 0.305 |
| CLV_PCSK_SKI1_1 | 192 | 196 | PF00082 | 0.529 |
| DOC_MAPK_gen_1 | 9 | 16 | PF00069 | 0.449 |
| DOC_PP1_RVXF_1 | 52 | 58 | PF00149 | 0.494 |
| DOC_USP7_MATH_1 | 93 | 97 | PF00917 | 0.520 |
| DOC_USP7_UBL2_3 | 192 | 196 | PF12436 | 0.525 |
| LIG_BIR_II_1 | 1 | 5 | PF00653 | 0.308 |
| LIG_BRCT_BRCA1_1 | 103 | 107 | PF00533 | 0.437 |
| LIG_BRCT_BRCA1_1 | 184 | 188 | PF00533 | 0.482 |
| LIG_Clathr_ClatBox_1 | 126 | 130 | PF01394 | 0.530 |
| LIG_eIF4E_1 | 101 | 107 | PF01652 | 0.494 |
| LIG_eIF4E_1 | 60 | 66 | PF01652 | 0.493 |
| LIG_FHA_1 | 149 | 155 | PF00498 | 0.484 |
| LIG_FHA_1 | 39 | 45 | PF00498 | 0.591 |
| LIG_FHA_1 | 56 | 62 | PF00498 | 0.570 |
| LIG_FHA_2 | 161 | 167 | PF00498 | 0.469 |
| LIG_FHA_2 | 28 | 34 | PF00498 | 0.491 |
| LIG_FHA_2 | 35 | 41 | PF00498 | 0.438 |
| LIG_LIR_Gen_1 | 12 | 21 | PF02991 | 0.481 |
| LIG_LIR_Nem_3 | 104 | 110 | PF02991 | 0.437 |
| LIG_LIR_Nem_3 | 12 | 16 | PF02991 | 0.499 |
| LIG_LIR_Nem_3 | 185 | 191 | PF02991 | 0.649 |
| LIG_PTB_Apo_2 | 183 | 190 | PF02174 | 0.469 |
| LIG_REV1ctd_RIR_1 | 186 | 196 | PF16727 | 0.704 |
| LIG_SH2_CRK | 110 | 114 | PF00017 | 0.512 |
| LIG_SH2_PTP2 | 13 | 16 | PF00017 | 0.530 |
| LIG_SH2_PTP2 | 26 | 29 | PF00017 | 0.469 |
| LIG_SH2_STAT5 | 128 | 131 | PF00017 | 0.495 |
| LIG_SH2_STAT5 | 13 | 16 | PF00017 | 0.530 |
| LIG_SH2_STAT5 | 26 | 29 | PF00017 | 0.469 |
| LIG_SH2_STAT5 | 60 | 63 | PF00017 | 0.480 |
| LIG_SUMO_SIM_anti_2 | 166 | 172 | PF11976 | 0.480 |
| LIG_TRAF2_1 | 163 | 166 | PF00917 | 0.480 |
| MOD_CK1_1 | 78 | 84 | PF00069 | 0.608 |
| MOD_CK2_1 | 160 | 166 | PF00069 | 0.469 |
| MOD_CK2_1 | 27 | 33 | PF00069 | 0.512 |
| MOD_GlcNHglycan | 91 | 94 | PF01048 | 0.368 |
| MOD_GSK3_1 | 34 | 41 | PF00069 | 0.480 |
| MOD_GSK3_1 | 74 | 81 | PF00069 | 0.501 |
| MOD_GSK3_1 | 89 | 96 | PF00069 | 0.499 |
| MOD_LATS_1 | 73 | 79 | PF00433 | 0.512 |
| MOD_N-GLC_1 | 55 | 60 | PF02516 | 0.370 |
| MOD_NEK2_1 | 1 | 6 | PF00069 | 0.309 |
| MOD_PIKK_1 | 160 | 166 | PF00454 | 0.558 |
| MOD_PIKK_1 | 34 | 40 | PF00454 | 0.494 |
| MOD_PKA_2 | 74 | 80 | PF00069 | 0.492 |
| MOD_SUMO_rev_2 | 31 | 37 | PF00179 | 0.469 |
| TRG_DiLeu_BaEn_1 | 166 | 171 | PF01217 | 0.469 |
| TRG_ENDOCYTIC_2 | 13 | 16 | PF00928 | 0.530 |
| TRG_ENDOCYTIC_2 | 26 | 29 | PF00928 | 0.469 |
| TRG_ER_diArg_1 | 180 | 182 | PF00400 | 0.558 |
| TRG_ER_diArg_1 | 94 | 97 | PF00400 | 0.469 |
| Protein | Taxonomy | Sequence identity | Coverage |
|---|---|---|---|
| A0A0N1ILF0 | Leptomonas seymouri | 24% | 83% |
| A0A0N1ILR7 | Leptomonas seymouri | 87% | 100% |
| A0A0S4J7A1 | Bodo saltans | 27% | 83% |
| A0A0S4JIF5 | Bodo saltans | 61% | 100% |
| A0A1X0P8B0 | Trypanosomatidae | 65% | 94% |
| A0A3S5ISK6 | Trypanosoma rangeli | 69% | 100% |
| A0A3S7XA80 | Leishmania donovani | 97% | 100% |
| A1RSJ8 | Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3) | 24% | 100% |
| A4HNP0 | Leishmania braziliensis | 89% | 100% |
| A4ICV5 | Leishmania infantum | 97% | 100% |
| A5DB52 | Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) | 36% | 100% |
| A5UM14 | Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS) | 24% | 100% |
| A9A2U7 | Nitrosopumilus maritimus (strain SCM1) | 22% | 98% |
| D0A2J4 | Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) | 70% | 100% |
| O23714 | Arabidopsis thaliana | 40% | 100% |
| O24633 | Arabidopsis thaliana | 40% | 100% |
| O50110 | Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) | 28% | 100% |
| P0CQ12 | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) | 33% | 92% |
| P0CQ13 | Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) | 33% | 92% |
| P22141 | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) | 36% | 100% |
| P40307 | Rattus norvegicus | 34% | 100% |
| P49721 | Homo sapiens | 34% | 100% |
| P91477 | Caenorhabditis elegans | 31% | 100% |
| Q09720 | Schizosaccharomyces pombe (strain 972 / ATCC 24843) | 36% | 100% |
| Q2NI68 | Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3) | 24% | 100% |
| Q4Q246 | Leishmania major | 97% | 100% |
| Q55DY7 | Dictyostelium discoideum | 40% | 100% |
| Q5E9K0 | Bos taurus | 34% | 100% |
| Q5JDJ9 | Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) | 23% | 100% |
| Q8SRF1 | Encephalitozoon cuniculi (strain GB-M1) | 26% | 100% |
| Q8U125 | Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) | 26% | 100% |
| Q8ZST5 | Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2) | 25% | 100% |
| Q9LST6 | Oryza sativa subsp. japonica | 40% | 97% |
| Q9NHC6 | Trypanosoma brucei brucei | 69% | 100% |
| Q9P6U7 | Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) | 38% | 100% |
| Q9R1P3 | Mus musculus | 34% | 100% |
| Q9V0N9 | Pyrococcus abyssi (strain GE5 / Orsay) | 26% | 100% |
| Q9VQE5 | Drosophila melanogaster | 32% | 98% |
| V5C017 | Trypanosoma cruzi | 70% | 100% |