BZIP domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Afadin- and alpha -actinin-Binding, putative

Species:

Leishmania mexicana

UniProt:

E9ASE1_LEIMU

TriTrypDb:

LmxM.36.0240

Length:

224

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASE1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASE1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	103	107	PF00656	0.480
CLV_C14_Caspase3-7	25	29	PF00656	0.453
CLV_NRD_NRD_1	124	126	PF00675	0.611
CLV_NRD_NRD_1	138	140	PF00675	0.495
CLV_NRD_NRD_1	183	185	PF00675	0.480
CLV_NRD_NRD_1	187	189	PF00675	0.443
CLV_NRD_NRD_1	57	59	PF00675	0.540
CLV_NRD_NRD_1	70	72	PF00675	0.667
CLV_PCSK_KEX2_1	124	126	PF00082	0.551
CLV_PCSK_KEX2_1	138	140	PF00082	0.458
CLV_PCSK_KEX2_1	156	158	PF00082	0.436
CLV_PCSK_KEX2_1	183	185	PF00082	0.472
CLV_PCSK_KEX2_1	57	59	PF00082	0.545
CLV_PCSK_PC1ET2_1	156	158	PF00082	0.627
CLV_PCSK_SKI1_1	189	193	PF00082	0.461
DEG_APCC_DBOX_1	162	170	PF00400	0.348
DEG_Nend_Nbox_1	1	3	PF02207	0.603
DEG_SPOP_SBC_1	23	27	PF00917	0.486
DOC_CYCLIN_RxL_1	183	195	PF00134	0.464
DOC_MAPK_gen_1	42	51	PF00069	0.490
DOC_MAPK_RevD_3	191	207	PF00069	0.372
DOC_USP7_MATH_1	113	117	PF00917	0.577
DOC_WW_Pin1_4	63	68	PF00397	0.585
DOC_WW_Pin1_4	94	99	PF00397	0.511
LIG_14-3-3_CanoR_1	124	128	PF00244	0.584
LIG_14-3-3_CanoR_1	17	22	PF00244	0.709
LIG_14-3-3_CanoR_1	57	67	PF00244	0.594
LIG_Actin_WH2_2	152	169	PF00022	0.497
LIG_BRCT_BRCA1_1	96	100	PF00533	0.508
LIG_eIF4E_1	104	110	PF01652	0.511
LIG_eIF4E_1	87	93	PF01652	0.579
LIG_FHA_2	124	130	PF00498	0.631
LIG_FHA_2	23	29	PF00498	0.614
LIG_LIR_Nem_3	83	89	PF02991	0.578
LIG_MYND_1	94	98	PF01753	0.513
LIG_SH2_STAP1	104	108	PF00017	0.470
LIG_SH3_2	67	72	PF14604	0.609
LIG_SH3_3	62	68	PF00018	0.610
LIG_SH3_3	8	14	PF00018	0.588
LIG_SUMO_SIM_anti_2	105	112	PF11976	0.457
MOD_CK1_1	173	179	PF00069	0.512
MOD_CK1_1	61	67	PF00069	0.487
MOD_CK2_1	41	47	PF00069	0.715
MOD_CK2_1	63	69	PF00069	0.668
MOD_DYRK1A_RPxSP_1	63	67	PF00069	0.763
MOD_GlcNHglycan	115	118	PF01048	0.575
MOD_GlcNHglycan	120	123	PF01048	0.588
MOD_GSK3_1	57	64	PF00069	0.588
MOD_N-GLC_1	211	216	PF02516	0.463
MOD_NEK2_1	100	105	PF00069	0.518
MOD_NEK2_1	145	150	PF00069	0.580
MOD_PKA_1	57	63	PF00069	0.561
MOD_PKA_2	123	129	PF00069	0.559
MOD_PKA_2	41	47	PF00069	0.662
MOD_PKA_2	57	63	PF00069	0.472
MOD_Plk_1	145	151	PF00069	0.376
MOD_Plk_1	211	217	PF00069	0.462
MOD_Plk_4	17	23	PF00069	0.556
MOD_Plk_4	88	94	PF00069	0.643
MOD_ProDKin_1	63	69	PF00069	0.588
MOD_ProDKin_1	94	100	PF00069	0.510
MOD_SUMO_for_1	155	158	PF00179	0.601
MOD_SUMO_rev_2	171	176	PF00179	0.432
TRG_DiLeu_BaEn_1	88	93	PF01217	0.576
TRG_ER_diArg_1	162	165	PF00400	0.346
TRG_ER_diArg_1	51	54	PF00400	0.718
TRG_Pf-PMV_PEXEL_1	125	129	PF00026	0.598
TRG_Pf-PMV_PEXEL_1	139	143	PF00026	0.517

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I5U6	Leptomonas seymouri	62%	98%
A0A1X0P8P1	Trypanosomatidae	37%	97%
A0A3Q8IQF0	Leishmania donovani	94%	100%
A0A422P2B9	Trypanosoma rangeli	39%	98%
A4HNN2	Leishmania braziliensis	78%	100%
A4ICW3	Leishmania infantum	94%	100%
D0A2I6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
Q4Q254	Leishmania major	92%	100%