LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Secreted protein
Gene product:
Protein of unknown function (DUF2946), putative
Species:
Leishmania mexicana
UniProt:
E9ASB7_LEIMU
TriTrypDb:
Length:
137

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Cellular components
Term Name Level Count
GO:0016020 membrane 2 2
GO:0110165 cellular anatomical entity 1 2

Expansion

Sequence features

E9ASB7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASB7

Putative motif mimicry

Leishmania From To Domain/Motif Score
DOC_CKS1_1 108 113 PF01111 0.789
DOC_MAPK_gen_1 38 48 PF00069 0.765
DOC_MAPK_MEF2A_6 41 50 PF00069 0.758
DOC_WW_Pin1_4 107 112 PF00397 0.784
DOC_WW_Pin1_4 128 133 PF00397 0.823
LIG_BIR_II_1 1 5 PF00653 0.449
LIG_FHA_1 108 114 PF00498 0.792
LIG_FHA_2 17 23 PF00498 0.740
LIG_LIR_Gen_1 131 137 PF02991 0.689
LIG_LIR_Nem_3 131 137 PF02991 0.689
LIG_PDZ_Class_1 132 137 PF00595 0.687
LIG_SH2_CRK 61 65 PF00017 0.711
LIG_SH2_CRK 66 70 PF00017 0.387
LIG_SH2_GRB2like 134 137 PF00017 0.686
LIG_SH2_STAP1 66 70 PF00017 0.449
LIG_SH2_STAT5 61 64 PF00017 0.726
LIG_SH2_STAT5 66 69 PF00017 0.504
LIG_SH3_3 90 96 PF00018 0.794
LIG_TYR_ITIM 64 69 PF00017 0.560
MOD_CK1_1 124 130 PF00069 0.830
MOD_CK1_1 2 8 PF00069 0.549
MOD_GlcNHglycan 123 126 PF01048 0.631
MOD_GSK3_1 124 131 PF00069 0.830
MOD_GSK3_1 81 88 PF00069 0.722
MOD_NEK2_1 3 8 PF00069 0.549
MOD_NEK2_1 64 69 PF00069 0.560
MOD_NEK2_1 83 88 PF00069 0.387
MOD_PKA_2 94 100 PF00069 0.802
MOD_Plk_4 64 70 PF00069 0.562
MOD_ProDKin_1 107 113 PF00069 0.787
MOD_ProDKin_1 128 134 PF00069 0.821
MOD_SUMO_for_1 125 128 PF00179 0.834
TRG_DiLeu_BaLyEn_6 109 114 PF01217 0.791
TRG_ENDOCYTIC_2 134 137 PF00928 0.686
TRG_ENDOCYTIC_2 61 64 PF00928 0.726
TRG_ENDOCYTIC_2 66 69 PF00928 0.504

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS