Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9ASB1_LEIMU

TriTrypDb:

LmxM.19.1580

Length:

394

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ASB1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASB1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	268	272	PF00656	0.646
CLV_NRD_NRD_1	14	16	PF00675	0.584
CLV_NRD_NRD_1	235	237	PF00675	0.724
CLV_PCSK_KEX2_1	14	16	PF00082	0.554
CLV_PCSK_KEX2_1	2	4	PF00082	0.561
CLV_PCSK_KEX2_1	235	237	PF00082	0.724
CLV_PCSK_PC1ET2_1	14	16	PF00082	0.554
CLV_PCSK_PC1ET2_1	2	4	PF00082	0.561
CLV_PCSK_SKI1_1	235	239	PF00082	0.565
CLV_PCSK_SKI1_1	365	369	PF00082	0.559
CLV_PCSK_SKI1_1	60	64	PF00082	0.589
DEG_APCC_DBOX_1	234	242	PF00400	0.433
DEG_APCC_DBOX_1	59	67	PF00400	0.591
DEG_Nend_UBRbox_1	1	4	PF02207	0.545
DOC_CYCLIN_yCln2_LP_2	248	254	PF00134	0.623
DOC_MAPK_gen_1	232	240	PF00069	0.580
DOC_MAPK_gen_1	37	45	PF00069	0.450
DOC_PP4_FxxP_1	317	320	PF00568	0.515
DOC_USP7_MATH_1	343	347	PF00917	0.558
DOC_WW_Pin1_4	19	24	PF00397	0.473
DOC_WW_Pin1_4	219	224	PF00397	0.699
DOC_WW_Pin1_4	250	255	PF00397	0.547
DOC_WW_Pin1_4	335	340	PF00397	0.593
LIG_14-3-3_CanoR_1	15	25	PF00244	0.549
LIG_14-3-3_CanoR_1	204	213	PF00244	0.543
LIG_14-3-3_CanoR_1	243	249	PF00244	0.494
LIG_14-3-3_CanoR_1	3	11	PF00244	0.519
LIG_14-3-3_CanoR_1	342	352	PF00244	0.584
LIG_14-3-3_CanoR_1	365	370	PF00244	0.595
LIG_14-3-3_CanoR_1	86	90	PF00244	0.654
LIG_Actin_WH2_2	316	331	PF00022	0.574
LIG_BRCT_BRCA1_1	184	188	PF00533	0.552
LIG_Clathr_ClatBox_1	68	72	PF01394	0.636
LIG_FHA_1	20	26	PF00498	0.459
LIG_FHA_2	375	381	PF00498	0.597
LIG_FHA_2	59	65	PF00498	0.492
LIG_GBD_Chelix_1	241	249	PF00786	0.656
LIG_LIR_Gen_1	111	121	PF02991	0.542
LIG_LIR_Gen_1	210	221	PF02991	0.719
LIG_LIR_Gen_1	262	270	PF02991	0.594
LIG_LIR_Nem_3	111	117	PF02991	0.550
LIG_LIR_Nem_3	185	191	PF02991	0.534
LIG_LIR_Nem_3	210	216	PF02991	0.721
LIG_LIR_Nem_3	262	267	PF02991	0.598
LIG_LIR_Nem_3	88	92	PF02991	0.611
LIG_NRBOX	65	71	PF00104	0.644
LIG_SH3_3	125	131	PF00018	0.580
LIG_SH3_3	191	197	PF00018	0.569
LIG_SH3_3	248	254	PF00018	0.560
LIG_SH3_3	264	270	PF00018	0.587
LIG_SH3_4	73	80	PF00018	0.464
LIG_SUMO_SIM_anti_2	168	174	PF11976	0.560
LIG_SUMO_SIM_anti_2	64	70	PF11976	0.555
LIG_SUMO_SIM_par_1	117	122	PF11976	0.690
LIG_SUMO_SIM_par_1	40	46	PF11976	0.654
LIG_SUMO_SIM_par_1	67	72	PF11976	0.640
LIG_TRAF2_1	377	380	PF00917	0.658
LIG_UBA3_1	385	390	PF00899	0.416
LIG_UBA3_1	68	73	PF00899	0.502
MOD_CDC14_SPxK_1	222	225	PF00782	0.586
MOD_CDK_SPK_2	250	255	PF00069	0.550
MOD_CDK_SPxK_1	219	225	PF00069	0.588
MOD_CDK_SPxxK_3	335	342	PF00069	0.587
MOD_CK1_1	307	313	PF00069	0.609
MOD_CK1_1	338	344	PF00069	0.595
MOD_CK2_1	102	108	PF00069	0.462
MOD_CK2_1	244	250	PF00069	0.702
MOD_CK2_1	256	262	PF00069	0.562
MOD_CK2_1	295	301	PF00069	0.656
MOD_CK2_1	374	380	PF00069	0.538
MOD_CK2_1	58	64	PF00069	0.573
MOD_GlcNHglycan	184	187	PF01048	0.558
MOD_GlcNHglycan	199	202	PF01048	0.595
MOD_GlcNHglycan	289	293	PF01048	0.773
MOD_GlcNHglycan	297	300	PF01048	0.597
MOD_GlcNHglycan	382	385	PF01048	0.625
MOD_GSK3_1	211	218	PF00069	0.670
MOD_GSK3_1	370	377	PF00069	0.565
MOD_GSK3_1	380	387	PF00069	0.514
MOD_GSK3_1	72	79	PF00069	0.577
MOD_NEK2_1	1	6	PF00069	0.632
MOD_NEK2_1	324	329	PF00069	0.662
MOD_PKA_2	224	230	PF00069	0.431
MOD_PKA_2	85	91	PF00069	0.493
MOD_Plk_1	256	262	PF00069	0.641
MOD_Plk_4	108	114	PF00069	0.619
MOD_Plk_4	119	125	PF00069	0.457
MOD_Plk_4	160	166	PF00069	0.666
MOD_Plk_4	244	250	PF00069	0.578
MOD_Plk_4	64	70	PF00069	0.551
MOD_ProDKin_1	19	25	PF00069	0.473
MOD_ProDKin_1	219	225	PF00069	0.697
MOD_ProDKin_1	250	256	PF00069	0.549
MOD_ProDKin_1	335	341	PF00069	0.589
TRG_DiLeu_BaEn_1	168	173	PF01217	0.558
TRG_DiLeu_BaEn_1	64	69	PF01217	0.648
TRG_DiLeu_BaLyEn_6	20	25	PF01217	0.563
TRG_DiLeu_BaLyEn_6	233	238	PF01217	0.422
TRG_ER_diArg_1	177	180	PF00400	0.643
TRG_ER_diArg_1	235	237	PF00400	0.636
TRG_ER_diArg_1	36	39	PF00400	0.443
TRG_NES_CRM1_1	129	141	PF08389	0.567
TRG_NES_CRM1_1	350	364	PF08389	0.453
TRG_NLS_Bipartite_1	2	19	PF00514	0.593
TRG_NLS_MonoExtN_4	14	19	PF00514	0.545
TRG_Pf-PMV_PEXEL_1	30	34	PF00026	0.576
TRG_Pf-PMV_PEXEL_1	342	347	PF00026	0.621

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IB12	Leptomonas seymouri	33%	100%
A0A3S7WVS2	Leishmania donovani	88%	100%
A4HAA7	Leishmania braziliensis	72%	100%
A4HYI7	Leishmania infantum	87%	100%
Q4QD51	Leishmania major	86%	100%