LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ASA5_LEIMU
TriTrypDb:
LmxM.19.1520
Length:
785

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

E9ASA5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASA5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 19 23 PF00656 0.622
CLV_NRD_NRD_1 136 138 PF00675 0.633
CLV_NRD_NRD_1 190 192 PF00675 0.678
CLV_NRD_NRD_1 323 325 PF00675 0.551
CLV_NRD_NRD_1 358 360 PF00675 0.439
CLV_NRD_NRD_1 383 385 PF00675 0.286
CLV_NRD_NRD_1 413 415 PF00675 0.676
CLV_NRD_NRD_1 431 433 PF00675 0.330
CLV_NRD_NRD_1 454 456 PF00675 0.445
CLV_NRD_NRD_1 617 619 PF00675 0.608
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P8A9 Leptomonas seymouri 69% 85%
A0A0S4JN96 Bodo saltans 47% 100%
A0A1X0P5Z6 Trypanosomatidae 53% 100%
A0A3Q8IBG1 Leishmania donovani 94% 100%
A0A3S5IRX2 Trypanosoma rangeli 52% 100%
A4HAA1 Leishmania braziliensis 85% 100%
A4HYI2 Leishmania infantum 94% 100%
D0A0V4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 52% 98%
Q4QD57 Leishmania major 94% 100%
V5B4C3 Trypanosoma cruzi 52% 87%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS