Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ASA5_LEIMU

TriTrypDb:

LmxM.19.1520

Length:

785

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

E9ASA5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ASA5

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	19	23	PF00656	0.622
CLV_NRD_NRD_1	136	138	PF00675	0.633
CLV_NRD_NRD_1	190	192	PF00675	0.678
CLV_NRD_NRD_1	323	325	PF00675	0.551
CLV_NRD_NRD_1	358	360	PF00675	0.439
CLV_NRD_NRD_1	383	385	PF00675	0.286
CLV_NRD_NRD_1	413	415	PF00675	0.676
CLV_NRD_NRD_1	431	433	PF00675	0.330
CLV_NRD_NRD_1	454	456	PF00675	0.445
CLV_NRD_NRD_1	617	619	PF00675	0.608

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8A9	Leptomonas seymouri	69%	85%
A0A0S4JN96	Bodo saltans	47%	100%
A0A1X0P5Z6	Trypanosomatidae	53%	100%
A0A3Q8IBG1	Leishmania donovani	94%	100%
A0A3S5IRX2	Trypanosoma rangeli	52%	100%
A4HAA1	Leishmania braziliensis	85%	100%
A4HYI2	Leishmania infantum	94%	100%
D0A0V4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	98%
Q4QD57	Leishmania major	94%	100%
V5B4C3	Trypanosoma cruzi	52%	87%

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