LeishMANIAdb
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PDZ domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
PDZ domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AS91_LEIMU
TriTrypDb:
LmxM.19.1370
Length:
741

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AS91
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AS91

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 11 15 PF00656 0.697
CLV_C14_Caspase3-7 413 417 PF00656 0.517
CLV_C14_Caspase3-7 422 426 PF00656 0.557
CLV_MEL_PAP_1 540 546 PF00089 0.329
CLV_NRD_NRD_1 249 251 PF00675 0.613
CLV_NRD_NRD_1 292 294 PF00675 0.633
CLV_NRD_NRD_1 310 312 PF00675 0.460
CLV_NRD_NRD_1 402 404 PF00675 0.543
CLV_NRD_NRD_1 629 631 PF00675 0.665
CLV_PCSK_FUR_1 399 403 PF00082 0.553
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P342 Leptomonas seymouri 39% 100%
A0A3Q8IBI1 Leishmania donovani 84% 99%
A4HA87 Leishmania braziliensis 65% 100%
A4HYG4 Leishmania infantum 84% 99%
Q4QD73 Leishmania major 83% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS