LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AS90_LEIMU
TriTrypDb:
LmxM.19.1365
Length:
124

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AS90
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AS90

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 4 6 PF00675 0.499
CLV_PCSK_KEX2_1 4 6 PF00082 0.499
CLV_PCSK_SKI1_1 4 8 PF00082 0.504
DEG_Nend_Nbox_1 1 3 PF02207 0.528
DEG_SCF_FBW7_1 99 105 PF00400 0.506
DOC_CKS1_1 99 104 PF01111 0.508
DOC_USP7_MATH_1 102 106 PF00917 0.671
DOC_USP7_MATH_1 37 41 PF00917 0.594
DOC_USP7_MATH_1 62 66 PF00917 0.496
DOC_WW_Pin1_4 98 103 PF00397 0.508
LIG_14-3-3_CanoR_1 5 11 PF00244 0.496
LIG_BRCT_BRCA1_1 86 90 PF00533 0.483
LIG_FHA_1 44 50 PF00498 0.525
LIG_FHA_1 94 100 PF00498 0.525
LIG_FHA_2 66 72 PF00498 0.446
LIG_LIR_Gen_1 105 113 PF02991 0.553
LIG_LIR_Nem_3 105 109 PF02991 0.603
LIG_LIR_Nem_3 87 93 PF02991 0.543
LIG_MYND_1 33 37 PF01753 0.481
LIG_PDZ_Class_1 119 124 PF00595 0.429
LIG_SH2_STAT5 77 80 PF00017 0.414
LIG_SH3_3 86 92 PF00018 0.553
LIG_SH3_3 96 102 PF00018 0.450
LIG_SUMO_SIM_anti_2 105 111 PF11976 0.439
LIG_SUMO_SIM_par_1 95 101 PF11976 0.518
LIG_TRAF2_1 69 72 PF00917 0.563
LIG_UBA3_1 109 116 PF00899 0.439
LIG_WRC_WIRS_1 103 108 PF05994 0.570
MOD_CK1_1 63 69 PF00069 0.718
MOD_CK1_1 81 87 PF00069 0.548
MOD_CK1_1 98 104 PF00069 0.388
MOD_CK2_1 102 108 PF00069 0.564
MOD_CK2_1 65 71 PF00069 0.567
MOD_Cter_Amidation 2 5 PF01082 0.518
MOD_GlcNHglycan 64 68 PF01048 0.703
MOD_GlcNHglycan 78 81 PF01048 0.573
MOD_GlcNHglycan 8 11 PF01048 0.487
MOD_GSK3_1 38 45 PF00069 0.567
MOD_GSK3_1 62 69 PF00069 0.624
MOD_GSK3_1 76 83 PF00069 0.534
MOD_GSK3_1 93 100 PF00069 0.533
MOD_NEK2_1 38 43 PF00069 0.528
MOD_NEK2_1 78 83 PF00069 0.535
MOD_NEK2_1 95 100 PF00069 0.498
MOD_PIKK_1 48 54 PF00454 0.522
MOD_PKA_2 43 49 PF00069 0.591
MOD_Plk_1 71 77 PF00069 0.552
MOD_Plk_4 102 108 PF00069 0.420
MOD_Plk_4 84 90 PF00069 0.649
MOD_ProDKin_1 98 104 PF00069 0.510
TRG_ER_diArg_1 4 6 PF00400 0.529

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3I1 Leptomonas seymouri 65% 100%
A0A3S7WVJ6 Leishmania donovani 92% 76%
A4HA86 Leishmania braziliensis 71% 100%
A4HYG5 Leishmania infantum 92% 76%
Q4QD74 Leishmania major 91% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS