Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania mexicana

UniProt:

E9AS89_LEIMU

TriTrypDb:

LmxM.19.1360

Length:

160

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

E9AS89

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AS89

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
DEG_APCC_DBOX_1	75	83	PF00400	0.650
DEG_Nend_UBRbox_3	1	3	PF02207	0.850
DEG_SPOP_SBC_1	26	30	PF00917	0.784
DOC_MAPK_DCC_7	126	136	PF00069	0.449
DOC_MAPK_MEF2A_6	120	129	PF00069	0.547
DOC_PP4_FxxP_1	39	42	PF00568	0.799
DOC_USP7_MATH_1	59	63	PF00917	0.798
DOC_USP7_UBL2_3	156	160	PF12436	0.785
DOC_WW_Pin1_4	16	21	PF00397	0.818
DOC_WW_Pin1_4	38	43	PF00397	0.802
LIG_14-3-3_CanoR_1	10	16	PF00244	0.820
LIG_14-3-3_CanoR_1	27	32	PF00244	0.571
LIG_14-3-3_CanoR_1	76	80	PF00244	0.650
LIG_BRCT_BRCA1_1	106	110	PF00533	0.617
LIG_FHA_1	11	17	PF00498	0.820
LIG_FHA_1	62	68	PF00498	0.789
LIG_LIR_Gen_1	19	26	PF02991	0.805
LIG_LIR_Gen_1	30	40	PF02991	0.647
LIG_LIR_Nem_3	19	24	PF02991	0.810
LIG_LIR_Nem_3	30	36	PF02991	0.642
LIG_Pex14_2	136	140	PF04695	0.549
LIG_SH2_PTP2	148	151	PF00017	0.549
LIG_SH2_PTP2	33	36	PF00017	0.779
LIG_SH2_SRC	148	151	PF00017	0.549
LIG_SH2_STAT5	148	151	PF00017	0.549
LIG_SH2_STAT5	15	18	PF00017	0.822
LIG_SH2_STAT5	33	36	PF00017	0.554
LIG_SH3_3	39	45	PF00018	0.804
LIG_TYR_ITIM	146	151	PF00017	0.549
LIG_TYR_ITIM	31	36	PF00017	0.780
MOD_CDK_SPK_2	38	43	PF00069	0.802
MOD_CK1_1	14	20	PF00069	0.693
MOD_CK1_1	22	28	PF00069	0.572
MOD_CK1_1	4	10	PF00069	0.827
MOD_CK1_1	41	47	PF00069	0.573
MOD_CK1_1	75	81	PF00069	0.650
MOD_GlcNHglycan	104	109	PF01048	0.809
MOD_GlcNHglycan	21	24	PF01048	0.385
MOD_GlcNHglycan	3	6	PF01048	0.632
MOD_GlcNHglycan	55	58	PF01048	0.627
MOD_GSK3_1	10	17	PF00069	0.821
MOD_GSK3_1	104	111	PF00069	0.615
MOD_GSK3_1	22	29	PF00069	0.645
MOD_GSK3_1	47	54	PF00069	0.830
MOD_LATS_1	8	14	PF00433	0.821
MOD_N-GLC_1	1	6	PF02516	0.639
MOD_NEK2_1	1	6	PF00069	0.839
MOD_OFUCOSY	58	63	PF10250	0.604
MOD_PIKK_1	108	114	PF00454	0.626
MOD_PKA_2	26	32	PF00069	0.784
MOD_PKA_2	59	65	PF00069	0.799
MOD_PKA_2	75	81	PF00069	0.449
MOD_Plk_4	11	17	PF00069	0.820
MOD_Plk_4	27	33	PF00069	0.584
MOD_Plk_4	75	81	PF00069	0.650
MOD_Plk_4	95	101	PF00069	0.199
MOD_ProDKin_1	16	22	PF00069	0.817
MOD_ProDKin_1	38	44	PF00069	0.802
TRG_ENDOCYTIC_2	148	151	PF00928	0.549
TRG_ENDOCYTIC_2	33	36	PF00928	0.779