LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AS83_LEIMU
TriTrypDb:
LmxM.19.1315
Length:
122

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 14
NetGPI no yes: 0, no: 14
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AS83
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AS83

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 4 6 PF00675 0.510
CLV_PCSK_KEX2_1 4 6 PF00082 0.510
CLV_PCSK_SKI1_1 4 8 PF00082 0.514
DEG_Nend_Nbox_1 1 3 PF02207 0.525
DOC_MAPK_MEF2A_6 30 37 PF00069 0.521
DOC_PP4_FxxP_1 106 109 PF00568 0.565
DOC_USP7_MATH_1 93 97 PF00917 0.498
DOC_WW_Pin1_4 105 110 PF00397 0.707
LIG_14-3-3_CanoR_1 5 11 PF00244 0.469
LIG_14-3-3_CanoR_1 59 65 PF00244 0.535
LIG_FHA_1 116 122 PF00498 0.397
LIG_SUMO_SIM_anti_2 34 39 PF11976 0.346
MOD_CK1_1 47 53 PF00069 0.544
MOD_CK1_1 60 66 PF00069 0.526
MOD_Cter_Amidation 2 5 PF01082 0.533
MOD_GlcNHglycan 49 52 PF01048 0.468
MOD_GlcNHglycan 60 63 PF01048 0.533
MOD_GlcNHglycan 78 81 PF01048 0.599
MOD_GlcNHglycan 8 11 PF01048 0.460
MOD_GlcNHglycan 95 98 PF01048 0.502
MOD_GSK3_1 105 112 PF00069 0.659
MOD_GSK3_1 53 60 PF00069 0.511
MOD_NEK2_1 104 109 PF00069 0.677
MOD_NEK2_1 57 62 PF00069 0.612
MOD_PKA_2 58 64 PF00069 0.590
MOD_ProDKin_1 105 111 PF00069 0.708
MOD_SUMO_rev_2 68 78 PF00179 0.635
TRG_DiLeu_BaEn_1 73 78 PF01217 0.685
TRG_ER_diArg_1 4 6 PF00400 0.510

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P3I1 Leptomonas seymouri 53% 100%
A0A0N0P7U0 Leptomonas seymouri 79% 99%
A0A0S4KKW4 Bodo saltans 37% 100%
A0A1X0P697 Trypanosomatidae 41% 98%
A0A3Q8IBH0 Leishmania donovani 93% 100%
A0A3S7WVJ6 Leishmania donovani 51% 74%
A4HYG5 Leishmania infantum 51% 74%
D0A0T3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 41% 100%
E9AHU8 Leishmania infantum 94% 100%
E9AI62 Leishmania braziliensis 76% 100%
Q4QD74 Leishmania major 51% 100%
Q4QD83 Leishmania major 93% 100%
V5D1C6 Trypanosoma cruzi 46% 90%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS