Chromosome partition protein Smc

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AS24_LEIMU

TriTrypDb:

LmxM.19.0720

Length:

275

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AS24

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AS24

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	100	104	PF00656	0.600
CLV_C14_Caspase3-7	226	230	PF00656	0.569
CLV_C14_Caspase3-7	69	73	PF00656	0.633
CLV_NRD_NRD_1	122	124	PF00675	0.499
CLV_NRD_NRD_1	262	264	PF00675	0.586
CLV_PCSK_SKI1_1	149	153	PF00082	0.553
CLV_PCSK_SKI1_1	168	172	PF00082	0.490
CLV_PCSK_SKI1_1	218	222	PF00082	0.616
CLV_PCSK_SKI1_1	96	100	PF00082	0.544
DEG_APCC_DBOX_1	167	175	PF00400	0.545
DEG_APCC_DBOX_1	217	225	PF00400	0.539
DEG_SPOP_SBC_1	268	272	PF00917	0.766
DOC_CYCLIN_RxL_1	145	156	PF00134	0.365
DOC_USP7_MATH_1	223	227	PF00917	0.576
DOC_USP7_UBL2_3	124	128	PF12436	0.582
DOC_WW_Pin1_4	264	269	PF00397	0.713
LIG_14-3-3_CanoR_1	216	224	PF00244	0.618
LIG_14-3-3_CanoR_1	96	102	PF00244	0.563
LIG_BIR_II_1	1	5	PF00653	0.434
LIG_BIR_III_4	72	76	PF00653	0.455
LIG_FHA_2	245	251	PF00498	0.579
LIG_LIR_Gen_1	243	254	PF02991	0.601
LIG_LIR_Nem_3	179	185	PF02991	0.505
LIG_LIR_Nem_3	237	242	PF02991	0.565
LIG_LIR_Nem_3	243	249	PF02991	0.582
LIG_NRP_CendR_1	274	275	PF00754	0.789
LIG_PCNA_yPIPBox_3	27	40	PF02747	0.616
LIG_RPA_C_Fungi	193	205	PF08784	0.545
LIG_TRAF2_1	184	187	PF00917	0.486
MOD_CK1_1	175	181	PF00069	0.559
MOD_CK1_1	267	273	PF00069	0.721
MOD_CK2_1	159	165	PF00069	0.587
MOD_CK2_1	181	187	PF00069	0.489
MOD_CK2_1	244	250	PF00069	0.514
MOD_GlcNHglycan	161	164	PF01048	0.631
MOD_GlcNHglycan	186	190	PF01048	0.503
MOD_GlcNHglycan	209	213	PF01048	0.615
MOD_GSK3_1	181	188	PF00069	0.488
MOD_GSK3_1	264	271	PF00069	0.685
MOD_LATS_1	122	128	PF00433	0.474
MOD_NEK2_1	259	264	PF00069	0.637
MOD_NEK2_1	8	13	PF00069	0.647
MOD_NEK2_2	269	274	PF00069	0.694
MOD_PIKK_1	8	14	PF00454	0.551
MOD_PKA_2	122	128	PF00069	0.579
MOD_PKA_2	159	165	PF00069	0.685
MOD_Plk_1	208	214	PF00069	0.587
MOD_Plk_4	35	41	PF00069	0.584
MOD_ProDKin_1	264	270	PF00069	0.717
MOD_SUMO_rev_2	69	76	PF00179	0.556
TRG_ER_diArg_1	273	275	PF00400	0.785
TRG_ER_diArg_1	52	55	PF00400	0.594
TRG_Pf-PMV_PEXEL_1	149	153	PF00026	0.457
TRG_Pf-PMV_PEXEL_1	27	31	PF00026	0.642

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIA8	Leptomonas seymouri	74%	90%
A0A1X0P7A5	Trypanosomatidae	35%	88%
A0A3Q8IB89	Leishmania donovani	93%	90%
A0A422NN36	Trypanosoma rangeli	34%	90%
A4HA29	Leishmania braziliensis	84%	100%
A4HY92	Leishmania infantum	93%	90%
D0A0M5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	96%
Q4QDE9	Leishmania major	93%	100%
V5B7K2	Trypanosoma cruzi	35%	90%