Putative U3 snoRNA-associated protein UTP11

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

U3 snoRNA-associated protein UTP11, putative

Species:

Leishmania mexicana

UniProt:

E9AS19_LEIMU

TriTrypDb:

LmxM.19.0670

Length:

361

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	11
GO:0030684	preribosome	3	11
GO:0032040	small-subunit processome	4	11
GO:0032991	protein-containing complex	1	11
GO:0043226	organelle	2	11
GO:0043228	non-membrane-bounded organelle	3	11
GO:0043229	intracellular organelle	3	11
GO:0043232	intracellular non-membrane-bounded organelle	4	11
GO:0110165	cellular anatomical entity	1	11
GO:1990904	ribonucleoprotein complex	2	11

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Expansion

Sequence features

E9AS19

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AS19

Function

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Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	11
GO:0006364	rRNA processing	8	11
GO:0006396	RNA processing	6	11
GO:0006725	cellular aromatic compound metabolic process	3	11
GO:0006807	nitrogen compound metabolic process	2	11
GO:0008152	metabolic process	1	11
GO:0009987	cellular process	1	11
GO:0016070	RNA metabolic process	5	11
GO:0016072	rRNA metabolic process	7	11
GO:0034470	ncRNA processing	7	11

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	227	231	PF00656	0.642
CLV_NRD_NRD_1	100	102	PF00675	0.314
CLV_NRD_NRD_1	113	115	PF00675	0.340
CLV_NRD_NRD_1	19	21	PF00675	0.389
CLV_NRD_NRD_1	213	215	PF00675	0.335
CLV_NRD_NRD_1	217	219	PF00675	0.325
CLV_NRD_NRD_1	225	227	PF00675	0.289
CLV_NRD_NRD_1	298	300	PF00675	0.519
CLV_NRD_NRD_1	333	335	PF00675	0.518
CLV_NRD_NRD_1	347	349	PF00675	0.457

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P8Z1	Leptomonas seymouri	82%	99%
A0A0S4INY9	Bodo saltans	38%	100%
A0A1X0P6A7	Trypanosomatidae	60%	100%
A0A3Q8IK07	Leishmania donovani	97%	100%
A0A3R7NS36	Trypanosoma rangeli	57%	100%
A4HA25	Leishmania braziliensis	89%	100%
D0A0L7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
Q9U178	Leishmania major	97%	100%
V5BX19	Trypanosoma cruzi	57%	100%

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