J domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

DnaJ domain containing protein, putative

Species:

Leishmania mexicana

UniProt:

E9ARV9_LEIMU

TriTrypDb:

LmxM.19.0080

Length:

432

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 12
NetGPI	no	yes: 0, no: 12

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ARV9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARV9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	296	300	PF00656	0.709
CLV_NRD_NRD_1	104	106	PF00675	0.698
CLV_NRD_NRD_1	157	159	PF00675	0.552
CLV_NRD_NRD_1	179	181	PF00675	0.500
CLV_NRD_NRD_1	190	192	PF00675	0.477
CLV_NRD_NRD_1	214	216	PF00675	0.509
CLV_NRD_NRD_1	266	268	PF00675	0.551
CLV_NRD_NRD_1	302	304	PF00675	0.636
CLV_NRD_NRD_1	375	377	PF00675	0.552
CLV_NRD_NRD_1	387	389	PF00675	0.500
CLV_NRD_NRD_1	398	400	PF00675	0.470
CLV_NRD_NRD_1	69	71	PF00675	0.550
CLV_PCSK_FUR_1	214	218	PF00082	0.554
CLV_PCSK_KEX2_1	157	159	PF00082	0.579
CLV_PCSK_KEX2_1	179	181	PF00082	0.495
CLV_PCSK_KEX2_1	189	191	PF00082	0.477
CLV_PCSK_KEX2_1	214	216	PF00082	0.532
CLV_PCSK_KEX2_1	229	231	PF00082	0.493
CLV_PCSK_KEX2_1	258	260	PF00082	0.555
CLV_PCSK_KEX2_1	265	267	PF00082	0.522
CLV_PCSK_KEX2_1	302	304	PF00082	0.664
CLV_PCSK_KEX2_1	336	338	PF00082	0.537
CLV_PCSK_KEX2_1	377	379	PF00082	0.573
CLV_PCSK_KEX2_1	387	389	PF00082	0.527
CLV_PCSK_KEX2_1	398	400	PF00082	0.469
CLV_PCSK_KEX2_1	59	61	PF00082	0.347
CLV_PCSK_KEX2_1	69	71	PF00082	0.550
CLV_PCSK_PC1ET2_1	216	218	PF00082	0.553
CLV_PCSK_PC1ET2_1	229	231	PF00082	0.566
CLV_PCSK_PC1ET2_1	258	260	PF00082	0.603
CLV_PCSK_PC1ET2_1	336	338	PF00082	0.581
CLV_PCSK_PC1ET2_1	377	379	PF00082	0.532
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.347
CLV_PCSK_PC7_1	175	181	PF00082	0.576
CLV_PCSK_PC7_1	185	191	PF00082	0.552
CLV_PCSK_PC7_1	210	216	PF00082	0.610
CLV_PCSK_PC7_1	65	71	PF00082	0.637
CLV_PCSK_SKI1_1	108	112	PF00082	0.680
CLV_PCSK_SKI1_1	200	204	PF00082	0.611
CLV_PCSK_SKI1_1	210	214	PF00082	0.609
CLV_PCSK_SKI1_1	416	420	PF00082	0.524
CLV_PCSK_SKI1_1	65	69	PF00082	0.629
CLV_Separin_Metazoa	211	215	PF03568	0.528
DEG_Nend_UBRbox_2	1	3	PF02207	0.651
DOC_CYCLIN_RxL_1	22	35	PF00134	0.323
DOC_USP7_MATH_1	101	105	PF00917	0.554
DOC_USP7_MATH_1	418	422	PF00917	0.510
DOC_USP7_MATH_1	84	88	PF00917	0.674
DOC_USP7_MATH_1	93	97	PF00917	0.613
DOC_USP7_UBL2_3	225	229	PF12436	0.554
DOC_WW_Pin1_4	123	128	PF00397	0.734
DOC_WW_Pin1_4	85	90	PF00397	0.638
LIG_14-3-3_CanoR_1	108	116	PF00244	0.669
LIG_14-3-3_CanoR_1	137	145	PF00244	0.669
LIG_14-3-3_CanoR_1	365	372	PF00244	0.655
LIG_Actin_WH2_2	401	418	PF00022	0.506
LIG_APCC_ABBA_1	30	35	PF00400	0.323
LIG_FHA_1	367	373	PF00498	0.611
LIG_FHA_1	399	405	PF00498	0.509
LIG_FHA_1	422	428	PF00498	0.668
LIG_FHA_2	142	148	PF00498	0.653
LIG_FHA_2	366	372	PF00498	0.638
LIG_FHA_2	51	57	PF00498	0.440
LIG_FHA_2	66	72	PF00498	0.645
LIG_LIR_Gen_1	234	242	PF02991	0.623
LIG_LIR_Gen_1	5	12	PF02991	0.323
LIG_LIR_Nem_3	118	123	PF02991	0.573
LIG_LIR_Nem_3	133	139	PF02991	0.760
LIG_LIR_Nem_3	234	239	PF02991	0.572
LIG_LIR_Nem_3	41	47	PF02991	0.324
LIG_LIR_Nem_3	5	10	PF02991	0.323
LIG_PCNA_PIPBox_1	244	253	PF02747	0.520
LIG_Pex14_2	145	149	PF04695	0.535
LIG_RPA_C_Fungi	261	273	PF08784	0.637
LIG_SH2_CRK	51	55	PF00017	0.336
LIG_SH2_CRK	7	11	PF00017	0.336
LIG_SH2_NCK_1	236	240	PF00017	0.537
LIG_SH2_SRC	236	239	PF00017	0.600
LIG_SH2_STAP1	169	173	PF00017	0.524
LIG_SH2_STAP1	63	67	PF00017	0.476
LIG_SH2_STAT5	7	10	PF00017	0.418
LIG_SH3_3	83	89	PF00018	0.657
LIG_TRAF2_1	330	333	PF00917	0.635
LIG_TRAF2_1	338	341	PF00917	0.552
LIG_TRAF2_1	360	363	PF00917	0.588
MOD_CK1_1	126	132	PF00069	0.735
MOD_CK1_1	141	147	PF00069	0.634
MOD_CK1_1	421	427	PF00069	0.648
MOD_CK2_1	141	147	PF00069	0.574
MOD_CK2_1	365	371	PF00069	0.673
MOD_GlcNHglycan	128	131	PF01048	0.658
MOD_GlcNHglycan	391	397	PF01048	0.632
MOD_GlcNHglycan	420	423	PF01048	0.523
MOD_GlcNHglycan	60	63	PF01048	0.436
MOD_N-GLC_1	365	370	PF02516	0.648
MOD_NEK2_1	10	15	PF00069	0.418
MOD_PIKK_1	253	259	PF00454	0.577
MOD_PKA_1	398	404	PF00069	0.513
MOD_PKA_2	282	288	PF00069	0.765
MOD_PKA_2	366	372	PF00069	0.656
MOD_PKA_2	398	404	PF00069	0.505
MOD_Plk_1	392	398	PF00069	0.630
MOD_Plk_4	5	11	PF00069	0.418
MOD_ProDKin_1	123	129	PF00069	0.735
MOD_ProDKin_1	85	91	PF00069	0.639
MOD_SUMO_for_1	165	168	PF00179	0.609
MOD_SUMO_for_1	324	327	PF00179	0.643
MOD_SUMO_for_1	410	413	PF00179	0.589
MOD_SUMO_rev_2	218	227	PF00179	0.586
MOD_SUMO_rev_2	299	308	PF00179	0.570
MOD_SUMO_rev_2	327	335	PF00179	0.572
MOD_SUMO_rev_2	402	410	PF00179	0.549
MOD_SUMO_rev_2	428	432	PF00179	0.623
TRG_DiLeu_BaEn_4	263	269	PF01217	0.584
TRG_DiLeu_BaEn_4	339	345	PF01217	0.622
TRG_ENDOCYTIC_2	236	239	PF00928	0.507
TRG_ENDOCYTIC_2	51	54	PF00928	0.323
TRG_ENDOCYTIC_2	6	9	PF00928	0.337
TRG_ER_diArg_1	156	158	PF00400	0.662
TRG_ER_diArg_1	189	191	PF00400	0.538
TRG_ER_diArg_1	213	215	PF00400	0.529
TRG_ER_diArg_1	265	267	PF00400	0.509
TRG_ER_diArg_1	301	303	PF00400	0.664
TRG_ER_diArg_1	376	379	PF00400	0.663
TRG_ER_diArg_1	397	399	PF00400	0.472
TRG_NLS_MonoCore_2	104	109	PF00514	0.761
TRG_Pf-PMV_PEXEL_1	249	253	PF00026	0.567
TRG_Pf-PMV_PEXEL_1	259	263	PF00026	0.479
TRG_Pf-PMV_PEXEL_1	266	270	PF00026	0.463
TRG_Pf-PMV_PEXEL_1	342	347	PF00026	0.612
TRG_Pf-PMV_PEXEL_1	378	382	PF00026	0.517

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0G8	Leptomonas seymouri	71%	100%
A0A0S4IRH8	Bodo saltans	44%	97%
A0A0S4JH45	Bodo saltans	25%	100%
A0A1X0P7B2	Trypanosomatidae	50%	97%
A0A3Q8IA51	Leishmania donovani	97%	100%
A0A3R7MIW9	Trypanosoma rangeli	51%	97%
A4H9W5	Leishmania braziliensis	89%	100%
D0A0C8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	98%
E9AGR0	Leishmania infantum	97%	100%
Q4QDL3	Leishmania major	96%	100%
V5BWX2	Trypanosoma cruzi	51%	97%