Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ttaggg binding factor, putative

Species:

Leishmania mexicana

UniProt:

E9ARR2_LEIMU

TriTrypDb:

LmxM.18.1250

Length:

797

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ARR2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARR2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	336	340	PF00656	0.529
CLV_C14_Caspase3-7	375	379	PF00656	0.735
CLV_C14_Caspase3-7	430	434	PF00656	0.832
CLV_C14_Caspase3-7	481	485	PF00656	0.805
CLV_C14_Caspase3-7	495	499	PF00656	0.607
CLV_C14_Caspase3-7	503	507	PF00656	0.656
CLV_NRD_NRD_1	168	170	PF00675	0.868
CLV_NRD_NRD_1	244	246	PF00675	0.796
CLV_NRD_NRD_1	259	261	PF00675	0.607
CLV_NRD_NRD_1	294	296	PF00675	0.812
CLV_NRD_NRD_1	297	299	PF00675	0.641
CLV_NRD_NRD_1	321	323	PF00675	0.743
CLV_NRD_NRD_1	345	347	PF00675	0.680
CLV_NRD_NRD_1	655	657	PF00675	0.830
CLV_NRD_NRD_1	684	686	PF00675	0.610
CLV_NRD_NRD_1	740	742	PF00675	0.509
CLV_NRD_NRD_1	76	78	PF00675	0.520
CLV_PCSK_FUR_1	295	299	PF00082	0.751
CLV_PCSK_KEX2_1	168	170	PF00082	0.868
CLV_PCSK_KEX2_1	259	261	PF00082	0.731
CLV_PCSK_KEX2_1	294	296	PF00082	0.816
CLV_PCSK_KEX2_1	297	299	PF00082	0.643
CLV_PCSK_KEX2_1	321	323	PF00082	0.627
CLV_PCSK_KEX2_1	347	349	PF00082	0.686
CLV_PCSK_KEX2_1	367	369	PF00082	0.552
CLV_PCSK_KEX2_1	654	656	PF00082	0.814
CLV_PCSK_KEX2_1	683	685	PF00082	0.637
CLV_PCSK_KEX2_1	739	741	PF00082	0.514
CLV_PCSK_KEX2_1	76	78	PF00082	0.520
CLV_PCSK_PC1ET2_1	347	349	PF00082	0.837
CLV_PCSK_PC1ET2_1	367	369	PF00082	0.556
CLV_PCSK_PC7_1	735	741	PF00082	0.653
CLV_PCSK_SKI1_1	52	56	PF00082	0.700
CLV_PCSK_SKI1_1	530	534	PF00082	0.821
CLV_PCSK_SKI1_1	538	542	PF00082	0.701
CLV_PCSK_SKI1_1	554	558	PF00082	0.511
CLV_PCSK_SKI1_1	660	664	PF00082	0.715
CLV_PCSK_SKI1_1	725	729	PF00082	0.611
CLV_PCSK_SKI1_1	735	739	PF00082	0.642
DEG_SCF_FBW7_2	132	138	PF00400	0.685
DEG_SIAH_1	6	14	PF03145	0.545
DEG_SPOP_SBC_1	35	39	PF00917	0.548
DEG_SPOP_SBC_1	354	358	PF00917	0.801
DEG_SPOP_SBC_1	371	375	PF00917	0.528
DEG_SPOP_SBC_1	461	465	PF00917	0.742
DEG_SPOP_SBC_1	584	588	PF00917	0.603
DEG_SPOP_SBC_1	642	646	PF00917	0.740
DEG_SPOP_SBC_1	675	679	PF00917	0.838
DOC_CKS1_1	132	137	PF01111	0.765
DOC_CKS1_1	661	666	PF01111	0.633
DOC_CKS1_1	777	782	PF01111	0.815
DOC_CYCLIN_RxL_1	551	559	PF00134	0.547
DOC_CYCLIN_yCln2_LP_2	123	129	PF00134	0.743
DOC_CYCLIN_yCln2_LP_2	422	428	PF00134	0.690
DOC_MAPK_gen_1	722	730	PF00069	0.620
DOC_PP2B_LxvP_1	123	126	PF13499	0.811
DOC_PP2B_LxvP_1	338	341	PF13499	0.738
DOC_PP2B_LxvP_1	422	425	PF13499	0.684
DOC_PP2B_LxvP_1	87	90	PF13499	0.664
DOC_USP7_MATH_1	14	18	PF00917	0.607
DOC_USP7_MATH_1	153	157	PF00917	0.638
DOC_USP7_MATH_1	174	178	PF00917	0.683
DOC_USP7_MATH_1	182	186	PF00917	0.734
DOC_USP7_MATH_1	264	268	PF00917	0.704
DOC_USP7_MATH_1	355	359	PF00917	0.792
DOC_USP7_MATH_1	360	364	PF00917	0.698
DOC_USP7_MATH_1	372	376	PF00917	0.733
DOC_USP7_MATH_1	389	393	PF00917	0.492
DOC_USP7_MATH_1	532	536	PF00917	0.739
DOC_USP7_MATH_1	540	544	PF00917	0.657
DOC_USP7_MATH_1	570	574	PF00917	0.730
DOC_USP7_MATH_1	584	588	PF00917	0.708
DOC_USP7_MATH_1	589	593	PF00917	0.658
DOC_USP7_MATH_1	627	631	PF00917	0.772
DOC_USP7_MATH_1	633	637	PF00917	0.720
DOC_USP7_MATH_1	642	646	PF00917	0.583
DOC_USP7_MATH_1	744	748	PF00917	0.722
DOC_USP7_MATH_1	754	758	PF00917	0.656
DOC_WW_Pin1_4	125	130	PF00397	0.758
DOC_WW_Pin1_4	131	136	PF00397	0.708
DOC_WW_Pin1_4	138	143	PF00397	0.613
DOC_WW_Pin1_4	157	162	PF00397	0.692
DOC_WW_Pin1_4	172	177	PF00397	0.563
DOC_WW_Pin1_4	178	183	PF00397	0.629
DOC_WW_Pin1_4	196	201	PF00397	0.540
DOC_WW_Pin1_4	205	210	PF00397	0.677
DOC_WW_Pin1_4	238	243	PF00397	0.853
DOC_WW_Pin1_4	250	255	PF00397	0.565
DOC_WW_Pin1_4	585	590	PF00397	0.677
DOC_WW_Pin1_4	660	665	PF00397	0.654
DOC_WW_Pin1_4	686	691	PF00397	0.684
DOC_WW_Pin1_4	770	775	PF00397	0.825
DOC_WW_Pin1_4	776	781	PF00397	0.721
DOC_WW_Pin1_4	9	14	PF00397	0.720
LIG_14-3-3_CanoR_1	100	105	PF00244	0.644
LIG_14-3-3_CanoR_1	168	174	PF00244	0.589
LIG_14-3-3_CanoR_1	604	612	PF00244	0.672
LIG_14-3-3_CanoR_1	722	731	PF00244	0.621
LIG_14-3-3_CanoR_1	756	760	PF00244	0.544
LIG_14-3-3_CanoR_1	76	86	PF00244	0.651
LIG_BIR_III_2	484	488	PF00653	0.810
LIG_BRCT_BRCA1_1	706	710	PF00533	0.611
LIG_BRCT_BRCA1_1	94	98	PF00533	0.502
LIG_FHA_1	118	124	PF00498	0.620
LIG_FHA_1	251	257	PF00498	0.568
LIG_FHA_1	36	42	PF00498	0.633
LIG_FHA_1	391	397	PF00498	0.780
LIG_FHA_1	453	459	PF00498	0.621
LIG_FHA_1	467	473	PF00498	0.670
LIG_FHA_1	500	506	PF00498	0.551
LIG_FHA_1	589	595	PF00498	0.842
LIG_FHA_1	614	620	PF00498	0.739
LIG_FHA_1	624	630	PF00498	0.502
LIG_FHA_1	647	653	PF00498	0.801
LIG_FHA_1	677	683	PF00498	0.827
LIG_FHA_2	101	107	PF00498	0.640
LIG_FHA_2	190	196	PF00498	0.651
LIG_FHA_2	209	215	PF00498	0.645
LIG_FHA_2	615	621	PF00498	0.659
LIG_FHA_2	756	762	PF00498	0.542
LIG_GBD_Chelix_1	109	117	PF00786	0.656
LIG_Integrin_RGD_1	43	45	PF01839	0.751
LIG_LIR_Apic_2	411	417	PF02991	0.701
LIG_LIR_Apic_2	529	534	PF02991	0.818
LIG_LIR_Gen_1	707	717	PF02991	0.607
LIG_LIR_Nem_3	60	66	PF02991	0.539
LIG_LIR_Nem_3	707	713	PF02991	0.606
LIG_NRBOX	214	220	PF00104	0.730
LIG_NRBOX	264	270	PF00104	0.750
LIG_SH2_GRB2like	414	417	PF00017	0.775
LIG_SH2_PTP2	414	417	PF00017	0.747
LIG_SH2_SRC	414	417	PF00017	0.775
LIG_SH2_STAT5	315	318	PF00017	0.734
LIG_SH2_STAT5	414	417	PF00017	0.747
LIG_SH2_STAT5	63	66	PF00017	0.678
LIG_SH2_STAT5	712	715	PF00017	0.607
LIG_SH3_1	771	777	PF00018	0.829
LIG_SH3_3	123	129	PF00018	0.660
LIG_SH3_3	181	187	PF00018	0.605
LIG_SH3_3	236	242	PF00018	0.718
LIG_SH3_3	63	69	PF00018	0.660
LIG_SH3_3	666	672	PF00018	0.838
LIG_SH3_3	771	777	PF00018	0.829
LIG_SH3_4	58	65	PF00018	0.433
LIG_SUMO_SIM_anti_2	515	521	PF11976	0.761
LIG_SUMO_SIM_par_1	208	214	PF11976	0.638
LIG_SUMO_SIM_par_1	486	492	PF11976	0.526
LIG_SUMO_SIM_par_1	68	73	PF11976	0.636
LIG_SUMO_SIM_par_1	80	88	PF11976	0.397
LIG_TRAF2_1	427	430	PF00917	0.754
LIG_TRAF2_1	600	603	PF00917	0.539
LIG_TRAF2_1	618	621	PF00917	0.460
LIG_TRAF2_1	689	692	PF00917	0.651
LIG_TYR_ITIM	61	66	PF00017	0.698
MOD_CDK_SPK_2	201	206	PF00069	0.763
MOD_CDK_SPxxK_3	161	168	PF00069	0.795
MOD_CDK_SPxxK_3	238	245	PF00069	0.772
MOD_CDK_SPxxK_3	776	783	PF00069	0.651
MOD_CK1_1	128	134	PF00069	0.828
MOD_CK1_1	17	23	PF00069	0.615
MOD_CK1_1	172	178	PF00069	0.802
MOD_CK1_1	185	191	PF00069	0.576
MOD_CK1_1	199	205	PF00069	0.668
MOD_CK1_1	238	244	PF00069	0.852
MOD_CK1_1	250	256	PF00069	0.563
MOD_CK1_1	282	288	PF00069	0.708
MOD_CK1_1	358	364	PF00069	0.805
MOD_CK1_1	37	43	PF00069	0.759
MOD_CK1_1	431	437	PF00069	0.702
MOD_CK1_1	447	453	PF00069	0.806
MOD_CK1_1	571	577	PF00069	0.690
MOD_CK1_1	587	593	PF00069	0.719
MOD_CK1_1	622	628	PF00069	0.699
MOD_CK1_1	636	642	PF00069	0.628
MOD_CK1_1	643	649	PF00069	0.661
MOD_CK1_1	677	683	PF00069	0.836
MOD_CK1_1	88	94	PF00069	0.660
MOD_CK2_1	100	106	PF00069	0.452
MOD_CK2_1	229	235	PF00069	0.598
MOD_CK2_1	597	603	PF00069	0.523
MOD_CK2_1	614	620	PF00069	0.690
MOD_CK2_1	686	692	PF00069	0.626
MOD_CK2_1	755	761	PF00069	0.542
MOD_CK2_1	785	791	PF00069	0.799
MOD_CK2_1	88	94	PF00069	0.607
MOD_Cter_Amidation	243	246	PF01082	0.695
MOD_Cter_Amidation	365	368	PF01082	0.561
MOD_DYRK1A_RPxSP_1	157	161	PF00069	0.647
MOD_GlcNHglycan	14	17	PF01048	0.765
MOD_GlcNHglycan	187	190	PF01048	0.553
MOD_GlcNHglycan	19	22	PF01048	0.682
MOD_GlcNHglycan	249	252	PF01048	0.847
MOD_GlcNHglycan	285	288	PF01048	0.554
MOD_GlcNHglycan	358	361	PF01048	0.751
MOD_GlcNHglycan	363	366	PF01048	0.628
MOD_GlcNHglycan	374	377	PF01048	0.720
MOD_GlcNHglycan	45	49	PF01048	0.739
MOD_GlcNHglycan	509	513	PF01048	0.637
MOD_GlcNHglycan	526	529	PF01048	0.797
MOD_GlcNHglycan	534	537	PF01048	0.689
MOD_GlcNHglycan	538	541	PF01048	0.633
MOD_GlcNHglycan	542	545	PF01048	0.579
MOD_GlcNHglycan	591	594	PF01048	0.617
MOD_GlcNHglycan	605	608	PF01048	0.724
MOD_GlcNHglycan	620	624	PF01048	0.761
MOD_GlcNHglycan	629	632	PF01048	0.635
MOD_GlcNHglycan	640	643	PF01048	0.693
MOD_GlcNHglycan	7	10	PF01048	0.798
MOD_GlcNHglycan	706	709	PF01048	0.618
MOD_GlcNHglycan	746	749	PF01048	0.538
MOD_GSK3_1	1	8	PF00069	0.754
MOD_GSK3_1	117	124	PF00069	0.729
MOD_GSK3_1	134	141	PF00069	0.566
MOD_GSK3_1	153	160	PF00069	0.733
MOD_GSK3_1	174	181	PF00069	0.805
MOD_GSK3_1	185	192	PF00069	0.768
MOD_GSK3_1	201	208	PF00069	0.649
MOD_GSK3_1	278	285	PF00069	0.663
MOD_GSK3_1	354	361	PF00069	0.756
MOD_GSK3_1	366	373	PF00069	0.832
MOD_GSK3_1	416	423	PF00069	0.559
MOD_GSK3_1	428	435	PF00069	0.743
MOD_GSK3_1	443	450	PF00069	0.580
MOD_GSK3_1	461	468	PF00069	0.807
MOD_GSK3_1	532	539	PF00069	0.668
MOD_GSK3_1	570	577	PF00069	0.602
MOD_GSK3_1	583	590	PF00069	0.632
MOD_GSK3_1	619	626	PF00069	0.651
MOD_GSK3_1	634	641	PF00069	0.569
MOD_GSK3_1	642	649	PF00069	0.766
MOD_GSK3_1	744	751	PF00069	0.722
MOD_GSK3_1	755	762	PF00069	0.669
MOD_GSK3_1	88	95	PF00069	0.654
MOD_N-GLC_1	283	288	PF02516	0.670
MOD_N-GLC_1	450	455	PF02516	0.818
MOD_N-GLC_1	650	655	PF02516	0.641
MOD_NEK2_1	117	122	PF00069	0.394
MOD_NEK2_1	29	34	PF00069	0.556
MOD_NEK2_1	443	448	PF00069	0.827
MOD_NEK2_1	556	561	PF00069	0.665
MOD_NEK2_1	583	588	PF00069	0.638
MOD_NEK2_1	619	624	PF00069	0.758
MOD_NEK2_1	634	639	PF00069	0.546
MOD_NEK2_1	640	645	PF00069	0.770
MOD_NEK2_1	706	711	PF00069	0.491
MOD_NEK2_1	98	103	PF00069	0.646
MOD_NEK2_2	289	294	PF00069	0.560
MOD_PIKK_1	328	334	PF00454	0.704
MOD_PKA_2	17	23	PF00069	0.854
MOD_PKA_2	279	285	PF00069	0.662
MOD_PKA_2	603	609	PF00069	0.637
MOD_PKA_2	721	727	PF00069	0.330
MOD_PKA_2	755	761	PF00069	0.542
MOD_Plk_1	396	402	PF00069	0.462
MOD_Plk_1	574	580	PF00069	0.530
MOD_Plk_2-3	785	791	PF00069	0.799
MOD_Plk_4	264	270	PF00069	0.750
MOD_Plk_4	315	321	PF00069	0.730
MOD_Plk_4	438	444	PF00069	0.657
MOD_Plk_4	755	761	PF00069	0.542
MOD_ProDKin_1	125	131	PF00069	0.761
MOD_ProDKin_1	138	144	PF00069	0.613
MOD_ProDKin_1	157	163	PF00069	0.688
MOD_ProDKin_1	172	178	PF00069	0.563
MOD_ProDKin_1	196	202	PF00069	0.838
MOD_ProDKin_1	205	211	PF00069	0.667
MOD_ProDKin_1	238	244	PF00069	0.852
MOD_ProDKin_1	250	256	PF00069	0.563
MOD_ProDKin_1	585	591	PF00069	0.677
MOD_ProDKin_1	660	666	PF00069	0.656
MOD_ProDKin_1	686	692	PF00069	0.671
MOD_ProDKin_1	770	776	PF00069	0.827
MOD_ProDKin_1	9	15	PF00069	0.722
TRG_DiLeu_BaLyEn_6	552	557	PF01217	0.749
TRG_ENDOCYTIC_2	63	66	PF00928	0.678
TRG_ENDOCYTIC_2	717	720	PF00928	0.563
TRG_ER_diArg_1	168	171	PF00400	0.583
TRG_ER_diArg_1	259	261	PF00400	0.727
TRG_ER_diArg_1	293	295	PF00400	0.830
TRG_ER_diArg_1	297	299	PF00400	0.670
TRG_ER_diArg_1	320	322	PF00400	0.738
TRG_ER_diArg_1	343	346	PF00400	0.794
TRG_ER_diArg_1	348	351	PF00400	0.803
TRG_ER_diArg_1	654	656	PF00400	0.541
TRG_ER_diArg_1	682	685	PF00400	0.806
TRG_ER_diArg_1	738	741	PF00400	0.654
TRG_ER_diArg_1	75	77	PF00400	0.659
TRG_NLS_MonoCore_2	346	351	PF00514	0.842
TRG_NLS_MonoExtC_3	345	350	PF00514	0.840
TRG_NLS_MonoExtN_4	344	351	PF00514	0.812

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IB42	Leishmania donovani	83%	100%
A4H9N4	Leishmania braziliensis	65%	100%
A4HXZ8	Leishmania infantum	83%	100%
Q4QDR7	Leishmania major	82%	100%