LeishMANIAdb
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GYF domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
GYF domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ARN0_LEIMU
TriTrypDb:
LmxM.18.0930
Length:
872

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ARN0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARN0

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 153 157 PF00656 0.726
CLV_C14_Caspase3-7 160 164 PF00656 0.569
CLV_C14_Caspase3-7 214 218 PF00656 0.564
CLV_C14_Caspase3-7 388 392 PF00656 0.582
CLV_C14_Caspase3-7 459 463 PF00656 0.746
CLV_C14_Caspase3-7 609 613 PF00656 0.535
CLV_C14_Caspase3-7 852 856 PF00656 0.657
CLV_NRD_NRD_1 225 227 PF00675 0.525
CLV_NRD_NRD_1 333 335 PF00675 0.750
CLV_NRD_NRD_1 408 410 PF00675 0.751
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3S7WUY5 Leishmania donovani 76% 97%
A4H9K1 Leishmania braziliensis 56% 100%
A4HXW6 Leishmania infantum 76% 97%
Q4QDU9 Leishmania major 73% 99%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS