LeishMANIAdb
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RanBP2-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RanBP2-type domain-containing protein
Gene product:
Zn-finger in Ran binding protein and others/FYVE zinc finger, putative
Species:
Leishmania mexicana
UniProt:
E9ARJ8_LEIMU
TriTrypDb:
LmxM.18.0600
Length:
636

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ARJ8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARJ8

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0005488 binding 1 7
GO:0043167 ion binding 2 7
GO:0043169 cation binding 3 7
GO:0046872 metal ion binding 4 7
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 492 496 PF00656 0.574
CLV_NRD_NRD_1 249 251 PF00675 0.469
CLV_NRD_NRD_1 260 262 PF00675 0.492
CLV_NRD_NRD_1 519 521 PF00675 0.321
CLV_NRD_NRD_1 581 583 PF00675 0.321
CLV_NRD_NRD_1 624 626 PF00675 0.451
CLV_NRD_NRD_1 631 633 PF00675 0.594
CLV_PCSK_FUR_1 247 251 PF00082 0.467
CLV_PCSK_KEX2_1 249 251 PF00082 0.468
CLV_PCSK_KEX2_1 529 531 PF00082 0.365
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P2D5 Leptomonas seymouri 55% 100%
A0A3Q8I9Y5 Leishmania donovani 89% 100%
A4H9G8 Leishmania braziliensis 78% 99%
A4HXT6 Leishmania infantum 89% 100%
Q4QDY1 Leishmania major 89% 98%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS