Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9ARI9_LEIMU

TriTrypDb:

LmxM.18.0520

Length:

741

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ARI9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARI9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	119	123	PF00656	0.671
CLV_C14_Caspase3-7	226	230	PF00656	0.711
CLV_C14_Caspase3-7	358	362	PF00656	0.662
CLV_NRD_NRD_1	156	158	PF00675	0.721
CLV_NRD_NRD_1	231	233	PF00675	0.699
CLV_NRD_NRD_1	480	482	PF00675	0.522
CLV_NRD_NRD_1	483	485	PF00675	0.511
CLV_NRD_NRD_1	592	594	PF00675	0.669
CLV_NRD_NRD_1	617	619	PF00675	0.543
CLV_NRD_NRD_1	663	665	PF00675	0.545
CLV_NRD_NRD_1	711	713	PF00675	0.547
CLV_NRD_NRD_1	735	737	PF00675	0.432
CLV_NRD_NRD_1	76	78	PF00675	0.664
CLV_PCSK_FUR_1	481	485	PF00082	0.537
CLV_PCSK_KEX2_1	156	158	PF00082	0.721
CLV_PCSK_KEX2_1	231	233	PF00082	0.563
CLV_PCSK_KEX2_1	283	285	PF00082	0.692
CLV_PCSK_KEX2_1	482	484	PF00082	0.531
CLV_PCSK_KEX2_1	592	594	PF00082	0.674
CLV_PCSK_KEX2_1	617	619	PF00082	0.543
CLV_PCSK_KEX2_1	710	712	PF00082	0.552
CLV_PCSK_KEX2_1	735	737	PF00082	0.432
CLV_PCSK_KEX2_1	75	77	PF00082	0.663
CLV_PCSK_PC1ET2_1	283	285	PF00082	0.692
CLV_PCSK_PC1ET2_1	482	484	PF00082	0.531
CLV_PCSK_PC1ET2_1	75	77	PF00082	0.663
CLV_PCSK_PC7_1	71	77	PF00082	0.533
CLV_PCSK_SKI1_1	151	155	PF00082	0.666
CLV_PCSK_SKI1_1	337	341	PF00082	0.729
CLV_PCSK_SKI1_1	499	503	PF00082	0.556
CLV_PCSK_SKI1_1	593	597	PF00082	0.560
CLV_PCSK_SKI1_1	664	668	PF00082	0.566
CLV_PCSK_SKI1_1	77	81	PF00082	0.545
CLV_Separin_Metazoa	601	605	PF03568	0.539
DEG_APCC_DBOX_1	592	600	PF00400	0.559
DEG_SCF_FBW7_2	651	658	PF00400	0.501
DEG_SPOP_SBC_1	275	279	PF00917	0.696
DEG_SPOP_SBC_1	316	320	PF00917	0.673
DEG_SPOP_SBC_1	405	409	PF00917	0.682
DOC_CYCLIN_yCln2_LP_2	360	366	PF00134	0.647
DOC_CYCLIN_yCln2_LP_2	645	651	PF00134	0.697
DOC_MAPK_gen_1	622	630	PF00069	0.499
DOC_MAPK_gen_1	710	719	PF00069	0.546
DOC_MAPK_MEF2A_6	105	113	PF00069	0.631
DOC_PP2B_LxvP_1	645	648	PF13499	0.701
DOC_USP7_MATH_1	123	127	PF00917	0.775
DOC_USP7_MATH_1	192	196	PF00917	0.787
DOC_USP7_MATH_1	23	27	PF00917	0.744
DOC_USP7_MATH_1	275	279	PF00917	0.747
DOC_USP7_MATH_1	309	313	PF00917	0.792
DOC_USP7_MATH_1	316	320	PF00917	0.700
DOC_USP7_MATH_1	322	326	PF00917	0.614
DOC_USP7_MATH_1	335	339	PF00917	0.515
DOC_USP7_MATH_1	405	409	PF00917	0.558
DOC_USP7_MATH_1	410	414	PF00917	0.654
DOC_USP7_MATH_1	66	70	PF00917	0.589
DOC_USP7_MATH_1	82	86	PF00917	0.576
DOC_USP7_MATH_2	656	662	PF00917	0.564
DOC_USP7_UBL2_3	282	286	PF12436	0.695
DOC_WW_Pin1_4	105	110	PF00397	0.642
DOC_WW_Pin1_4	172	177	PF00397	0.722
DOC_WW_Pin1_4	286	291	PF00397	0.731
DOC_WW_Pin1_4	298	303	PF00397	0.776
DOC_WW_Pin1_4	305	310	PF00397	0.673
DOC_WW_Pin1_4	312	317	PF00397	0.616
DOC_WW_Pin1_4	328	333	PF00397	0.544
DOC_WW_Pin1_4	349	354	PF00397	0.729
DOC_WW_Pin1_4	406	411	PF00397	0.680
DOC_WW_Pin1_4	651	656	PF00397	0.642
LIG_14-3-3_CanoR_1	138	143	PF00244	0.528
LIG_14-3-3_CanoR_1	156	161	PF00244	0.712
LIG_14-3-3_CanoR_1	200	209	PF00244	0.535
LIG_14-3-3_CanoR_1	222	228	PF00244	0.711
LIG_14-3-3_CanoR_1	251	256	PF00244	0.542
LIG_14-3-3_CanoR_1	310	316	PF00244	0.774
LIG_14-3-3_CanoR_1	455	462	PF00244	0.503
LIG_14-3-3_CanoR_1	573	581	PF00244	0.548
LIG_14-3-3_CanoR_1	59	64	PF00244	0.715
LIG_14-3-3_CanoR_1	71	75	PF00244	0.580
LIG_14-3-3_CanoR_1	710	720	PF00244	0.546
LIG_14-3-3_CanoR_1	76	82	PF00244	0.540
LIG_Actin_WH2_2	559	577	PF00022	0.538
LIG_Actin_WH2_2	599	616	PF00022	0.497
LIG_APCC_ABBA_1	111	116	PF00400	0.643
LIG_APCC_ABBA_1	372	377	PF00400	0.668
LIG_BIR_II_1	1	5	PF00653	0.657
LIG_BIR_III_4	122	126	PF00653	0.545
LIG_CaM_IQ_9	606	621	PF13499	0.532
LIG_eIF4E_1	359	365	PF01652	0.652
LIG_FHA_1	23	29	PF00498	0.538
LIG_FHA_1	355	361	PF00498	0.687
LIG_FHA_1	500	506	PF00498	0.565
LIG_FHA_1	519	525	PF00498	0.499
LIG_FHA_1	558	564	PF00498	0.518
LIG_FHA_1	637	643	PF00498	0.590
LIG_FHA_1	712	718	PF00498	0.543
LIG_FHA_2	157	163	PF00498	0.668
LIG_LIR_Apic_2	203	208	PF02991	0.681
LIG_LIR_Nem_3	421	427	PF02991	0.587
LIG_SH2_CRK	205	209	PF00017	0.727
LIG_SH2_SRC	359	362	PF00017	0.659
LIG_SH2_SRC	695	698	PF00017	0.370
LIG_SH2_STAP1	695	699	PF00017	0.530
LIG_SH2_STAT3	720	723	PF00017	0.537
LIG_SH2_STAT5	359	362	PF00017	0.698
LIG_SH2_STAT5	615	618	PF00017	0.538
LIG_SH3_2	332	337	PF14604	0.686
LIG_SH3_3	310	316	PF00018	0.799
LIG_SH3_3	329	335	PF00018	0.660
LIG_SH3_3	409	415	PF00018	0.526
LIG_SH3_3	645	651	PF00018	0.697
LIG_SH3_3	76	82	PF00018	0.622
LIG_TRAF2_1	395	398	PF00917	0.696
LIG_TRAF2_1	429	432	PF00917	0.417
LIG_TRAF2_1	656	659	PF00917	0.614
LIG_UBA3_1	341	345	PF00899	0.805
LIG_WRC_WIRS_1	60	65	PF05994	0.544
MOD_CDK_SPK_2	172	177	PF00069	0.674
MOD_CDK_SPK_2	290	295	PF00069	0.712
MOD_CDK_SPK_2	305	310	PF00069	0.616
MOD_CDK_SPxxK_3	290	297	PF00069	0.730
MOD_CDK_SPxxK_3	298	305	PF00069	0.668
MOD_CK1_1	141	147	PF00069	0.734
MOD_CK1_1	195	201	PF00069	0.773
MOD_CK1_1	223	229	PF00069	0.749
MOD_CK1_1	239	245	PF00069	0.544
MOD_CK1_1	254	260	PF00069	0.626
MOD_CK1_1	301	307	PF00069	0.848
MOD_CK1_1	308	314	PF00069	0.740
MOD_CK1_1	315	321	PF00069	0.603
MOD_CK1_1	390	396	PF00069	0.537
MOD_CK1_1	408	414	PF00069	0.686
MOD_CK1_1	518	524	PF00069	0.655
MOD_CK1_1	552	558	PF00069	0.461
MOD_CK1_1	586	592	PF00069	0.569
MOD_CK1_1	61	67	PF00069	0.631
MOD_CK1_1	638	644	PF00069	0.535
MOD_CK1_1	69	75	PF00069	0.581
MOD_CK1_1	98	104	PF00069	0.648
MOD_CK2_1	227	233	PF00069	0.605
MOD_CK2_1	33	39	PF00069	0.652
MOD_CK2_1	524	530	PF00069	0.521
MOD_CK2_1	552	558	PF00069	0.615
MOD_CK2_1	61	67	PF00069	0.620
MOD_CK2_1	680	686	PF00069	0.541
MOD_CK2_1	719	725	PF00069	0.541
MOD_Cter_Amidation	733	736	PF01082	0.406
MOD_DYRK1A_RPxSP_1	105	109	PF00069	0.626
MOD_GlcNHglycan	125	128	PF01048	0.655
MOD_GlcNHglycan	188	191	PF01048	0.789
MOD_GlcNHglycan	197	200	PF01048	0.735
MOD_GlcNHglycan	202	205	PF01048	0.645
MOD_GlcNHglycan	238	241	PF01048	0.705
MOD_GlcNHglycan	25	28	PF01048	0.773
MOD_GlcNHglycan	265	268	PF01048	0.690
MOD_GlcNHglycan	320	323	PF01048	0.717
MOD_GlcNHglycan	517	520	PF01048	0.602
MOD_GlcNHglycan	527	530	PF01048	0.599
MOD_GlcNHglycan	543	546	PF01048	0.562
MOD_GlcNHglycan	549	552	PF01048	0.626
MOD_GlcNHglycan	737	740	PF01048	0.589
MOD_GlcNHglycan	89	92	PF01048	0.666
MOD_GlcNHglycan	97	100	PF01048	0.597
MOD_GSK3_1	132	139	PF00069	0.639
MOD_GSK3_1	216	223	PF00069	0.739
MOD_GSK3_1	236	243	PF00069	0.697
MOD_GSK3_1	251	258	PF00069	0.599
MOD_GSK3_1	259	266	PF00069	0.648
MOD_GSK3_1	269	276	PF00069	0.564
MOD_GSK3_1	286	293	PF00069	0.686
MOD_GSK3_1	301	308	PF00069	0.792
MOD_GSK3_1	311	318	PF00069	0.683
MOD_GSK3_1	349	356	PF00069	0.769
MOD_GSK3_1	400	407	PF00069	0.679
MOD_GSK3_1	634	641	PF00069	0.494
MOD_GSK3_1	66	73	PF00069	0.634
MOD_GSK3_1	719	726	PF00069	0.539
MOD_GSK3_1	77	84	PF00069	0.601
MOD_GSK3_1	94	101	PF00069	0.626
MOD_LATS_1	271	277	PF00433	0.704
MOD_N-GLC_1	263	268	PF02516	0.695
MOD_NEK2_1	185	190	PF00069	0.532
MOD_NEK2_1	227	232	PF00069	0.608
MOD_NEK2_1	317	322	PF00069	0.538
MOD_NEK2_1	517	522	PF00069	0.626
MOD_NEK2_1	524	529	PF00069	0.586
MOD_NEK2_1	547	552	PF00069	0.675
MOD_NEK2_1	58	63	PF00069	0.626
MOD_NEK2_1	613	618	PF00069	0.496
MOD_NEK2_1	719	724	PF00069	0.539
MOD_NEK2_2	335	340	PF00069	0.717
MOD_NEK2_2	66	71	PF00069	0.569
MOD_PIKK_1	220	226	PF00454	0.743
MOD_PIKK_1	382	388	PF00454	0.517
MOD_PIKK_1	552	558	PF00454	0.576
MOD_PIKK_1	586	592	PF00454	0.530
MOD_PIKK_1	719	725	PF00454	0.541
MOD_PK_1	75	81	PF00069	0.660
MOD_PKA_1	156	162	PF00069	0.710
MOD_PKA_1	710	716	PF00069	0.545
MOD_PKA_1	735	741	PF00069	0.450
MOD_PKA_1	75	81	PF00069	0.660
MOD_PKA_2	11	17	PF00069	0.554
MOD_PKA_2	156	162	PF00069	0.710
MOD_PKA_2	227	233	PF00069	0.566
MOD_PKA_2	260	266	PF00069	0.604
MOD_PKA_2	309	315	PF00069	0.671
MOD_PKA_2	390	396	PF00069	0.523
MOD_PKA_2	454	460	PF00069	0.501
MOD_PKA_2	524	530	PF00069	0.624
MOD_PKA_2	58	64	PF00069	0.634
MOD_PKA_2	586	592	PF00069	0.569
MOD_PKA_2	613	619	PF00069	0.533
MOD_PKA_2	70	76	PF00069	0.581
MOD_PKA_2	710	716	PF00069	0.545
MOD_PKA_2	735	741	PF00069	0.450
MOD_PKB_1	571	579	PF00069	0.537
MOD_Plk_1	33	39	PF00069	0.652
MOD_Plk_1	658	664	PF00069	0.554
MOD_Plk_1	686	692	PF00069	0.539
MOD_Plk_4	11	17	PF00069	0.542
MOD_Plk_4	240	246	PF00069	0.614
MOD_Plk_4	549	555	PF00069	0.477
MOD_ProDKin_1	105	111	PF00069	0.644
MOD_ProDKin_1	172	178	PF00069	0.721
MOD_ProDKin_1	286	292	PF00069	0.734
MOD_ProDKin_1	298	304	PF00069	0.777
MOD_ProDKin_1	305	311	PF00069	0.673
MOD_ProDKin_1	312	318	PF00069	0.616
MOD_ProDKin_1	328	334	PF00069	0.537
MOD_ProDKin_1	349	355	PF00069	0.730
MOD_ProDKin_1	406	412	PF00069	0.679
MOD_ProDKin_1	651	657	PF00069	0.640
MOD_SUMO_for_1	503	506	PF00179	0.573
MOD_SUMO_rev_2	279	289	PF00179	0.695
MOD_SUMO_rev_2	42	51	PF00179	0.528
TRG_DiLeu_BaEn_4	496	502	PF01217	0.550
TRG_DiLeu_BaEn_4	625	631	PF01217	0.545
TRG_DiLeu_BaEn_4	658	664	PF01217	0.593
TRG_ER_diArg_1	156	158	PF00400	0.721
TRG_ER_diArg_1	481	484	PF00400	0.535
TRG_ER_diArg_1	690	693	PF00400	0.545
TRG_ER_diArg_1	710	712	PF00400	0.345
TRG_NLS_MonoExtN_4	481	486	PF00514	0.540
TRG_Pf-PMV_PEXEL_1	665	669	PF00026	0.516
TRG_Pf-PMV_PEXEL_1	704	709	PF00026	0.510

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IAX8	Leishmania donovani	85%	99%
A4H9G0	Leishmania braziliensis	67%	100%
A4HXS7	Leishmania infantum	85%	99%
Q4QDZ0	Leishmania major	84%	100%