LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9ARG3_LEIMU
TriTrypDb:
LmxM.18.0260
Length:
118

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0005739 mitochondrion 5 1
GO:0020023 kinetoplast 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

E9ARG3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARG3

PDB structure(s): 7aih_BE , 7am2_BE , 7ane_BE

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 13 15 PF00675 0.664
CLV_NRD_NRD_1 49 51 PF00675 0.454
CLV_PCSK_KEX2_1 13 15 PF00082 0.698
CLV_PCSK_KEX2_1 49 51 PF00082 0.454
CLV_PCSK_KEX2_1 60 62 PF00082 0.467
CLV_PCSK_PC1ET2_1 60 62 PF00082 0.320
DEG_Nend_Nbox_1 1 3 PF02207 0.672
DOC_MAPK_gen_1 13 21 PF00069 0.557
DOC_MAPK_MEF2A_6 95 104 PF00069 0.440
DOC_PP1_RVXF_1 47 54 PF00149 0.453
DOC_PP2B_LxvP_1 25 28 PF13499 0.393
DOC_PP4_FxxP_1 73 76 PF00568 0.505
DOC_WW_Pin1_4 107 112 PF00397 0.420
DOC_WW_Pin1_4 19 24 PF00397 0.613
LIG_14-3-3_CanoR_1 13 21 PF00244 0.650
LIG_14-3-3_CanoR_1 30 35 PF00244 0.511
LIG_14-3-3_CanoR_1 49 54 PF00244 0.439
LIG_FHA_1 13 19 PF00498 0.415
LIG_LIR_Apic_2 71 76 PF02991 0.492
LIG_REV1ctd_RIR_1 37 46 PF16727 0.474
LIG_SH2_STAT5 103 106 PF00017 0.453
LIG_SH2_STAT5 86 89 PF00017 0.493
LIG_SH3_3 17 23 PF00018 0.523
LIG_SUMO_SIM_par_1 17 22 PF11976 0.484
MOD_CDK_SPxxK_3 19 26 PF00069 0.402
MOD_CK1_1 33 39 PF00069 0.491
MOD_CK1_1 80 86 PF00069 0.552
MOD_CK2_1 112 118 PF00069 0.470
MOD_GSK3_1 26 33 PF00069 0.582
MOD_LATS_1 47 53 PF00433 0.476
MOD_N-GLC_1 107 112 PF02516 0.420
MOD_NEK2_1 68 73 PF00069 0.453
MOD_PK_1 30 36 PF00069 0.508
MOD_PKA_1 49 55 PF00069 0.452
MOD_PKA_2 12 18 PF00069 0.658
MOD_PKA_2 49 55 PF00069 0.452
MOD_ProDKin_1 107 113 PF00069 0.417
MOD_ProDKin_1 19 25 PF00069 0.615
TRG_DiLeu_BaLyEn_6 3 8 PF01217 0.429
TRG_ER_diArg_1 49 51 PF00400 0.454

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IHE6 Leptomonas seymouri 83% 91%
A0A1X0P6R5 Trypanosomatidae 68% 100%
A0A3Q8ICZ2 Leishmania donovani 93% 100%
A0A3S5IS44 Trypanosoma rangeli 73% 100%
A4H9D0 Leishmania braziliensis 93% 100%
A4HXQ2 Leishmania infantum 93% 100%
B6DTE3 Bodo saltans 74% 100%
D0A030 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 70% 100%
Q4QE16 Leishmania major 93% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS