Putative 60S ribosomal protein L7

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L7, putative

Species:

Leishmania mexicana

UniProt:

E9ARG0_LEIMU

TriTrypDb:

LmxM.18.0230

Length:

298

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005840	ribosome	5	11
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12
GO:0005730	nucleolus	5	1
GO:0015934	large ribosomal subunit	4	1
GO:0022625	cytosolic large ribosomal subunit	5	1
GO:0032991	protein-containing complex	1	1
GO:0044391	ribosomal subunit	3	1
GO:1990904	ribonucleoprotein complex	2	1

Expansion

Sequence features

E9ARG0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARG0

Function

Biological processes
Term	Name	Level	Count
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	1
GO:0000470	maturation of LSU-rRNA	9	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1
GO:0016072	rRNA metabolic process	7	1
GO:0034470	ncRNA processing	7	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034660	ncRNA metabolic process	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0046483	heterocycle metabolic process	3	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0003735	structural constituent of ribosome	2	1
GO:0005198	structural molecule activity	1	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	130	132	PF00675	0.349
CLV_NRD_NRD_1	21	23	PF00675	0.459
CLV_NRD_NRD_1	229	231	PF00675	0.238
CLV_NRD_NRD_1	278	280	PF00675	0.427
CLV_NRD_NRD_1	294	296	PF00675	0.454
CLV_NRD_NRD_1	34	36	PF00675	0.409
CLV_NRD_NRD_1	42	44	PF00675	0.414
CLV_NRD_NRD_1	53	55	PF00675	0.514
CLV_NRD_NRD_1	74	76	PF00675	0.445
CLV_NRD_NRD_1	80	82	PF00675	0.420
CLV_NRD_NRD_1	94	96	PF00675	0.405
CLV_PCSK_KEX2_1	104	106	PF00082	0.395
CLV_PCSK_KEX2_1	189	191	PF00082	0.361
CLV_PCSK_KEX2_1	229	231	PF00082	0.238
CLV_PCSK_KEX2_1	294	296	PF00082	0.607
CLV_PCSK_KEX2_1	42	44	PF00082	0.448
CLV_PCSK_KEX2_1	53	55	PF00082	0.508
CLV_PCSK_KEX2_1	93	95	PF00082	0.433
CLV_PCSK_PC1ET2_1	104	106	PF00082	0.503
CLV_PCSK_PC1ET2_1	189	191	PF00082	0.395
CLV_PCSK_PC1ET2_1	294	296	PF00082	0.577
CLV_PCSK_PC1ET2_1	53	55	PF00082	0.419
CLV_PCSK_SKI1_1	240	244	PF00082	0.467
CLV_PCSK_SKI1_1	289	293	PF00082	0.488
CLV_Separin_Metazoa	226	230	PF03568	0.476
DEG_APCC_DBOX_1	167	175	PF00400	0.450
DEG_APCC_KENBOX_2	75	79	PF00400	0.402
DEG_ODPH_VHL_1	231	244	PF01847	0.393
DEG_SCF_FBW7_2	144	151	PF00400	0.459
DOC_CKS1_1	156	161	PF01111	0.470
DOC_CYCLIN_RxL_1	237	245	PF00134	0.421
DOC_MAPK_gen_1	103	113	PF00069	0.342
DOC_MAPK_gen_1	13	20	PF00069	0.495
DOC_MAPK_gen_1	131	138	PF00069	0.471
DOC_MAPK_gen_1	286	293	PF00069	0.483
DOC_MAPK_gen_1	93	99	PF00069	0.443
DOC_MAPK_MEF2A_6	107	115	PF00069	0.433
DOC_PP1_RVXF_1	93	100	PF00149	0.424
DOC_PP4_FxxP_1	236	239	PF00568	0.404
DOC_USP7_MATH_1	117	121	PF00917	0.467
DOC_USP7_MATH_1	285	289	PF00917	0.546
DOC_USP7_UBL2_3	3	7	PF12436	0.506
DOC_USP7_UBL2_3	49	53	PF12436	0.404
DOC_USP7_UBL2_3	57	61	PF12436	0.417
DOC_USP7_UBL2_3	85	89	PF12436	0.398
DOC_WW_Pin1_4	144	149	PF00397	0.411
DOC_WW_Pin1_4	155	160	PF00397	0.496
LIG_14-3-3_CanoR_1	142	147	PF00244	0.457
LIG_14-3-3_CanoR_1	22	26	PF00244	0.428
LIG_14-3-3_CanoR_1	246	251	PF00244	0.448
LIG_14-3-3_CanoR_1	56	64	PF00244	0.477
LIG_APCC_ABBAyCdc20_2	178	184	PF00400	0.479
LIG_FHA_1	148	154	PF00498	0.357
LIG_FHA_1	15	21	PF00498	0.478
LIG_FHA_1	186	192	PF00498	0.378
LIG_FHA_1	288	294	PF00498	0.389
LIG_FHA_2	217	223	PF00498	0.507
LIG_LIR_Apic_2	235	239	PF02991	0.372
LIG_LIR_Gen_1	158	166	PF02991	0.478
LIG_LIR_LC3C_4	110	115	PF02991	0.217
LIG_LIR_Nem_3	158	163	PF02991	0.477
LIG_LIR_Nem_3	260	265	PF02991	0.420
LIG_NRBOX	170	176	PF00104	0.295
LIG_SH2_CRK	205	209	PF00017	0.323
LIG_SH2_STAP1	139	143	PF00017	0.282
LIG_SH2_STAT5	265	268	PF00017	0.373
LIG_SH3_3	160	166	PF00018	0.368
LIG_SUMO_SIM_par_1	142	147	PF11976	0.356
LIG_WW_3	237	241	PF00397	0.399
MOD_CDK_SPK_2	144	149	PF00069	0.462
MOD_CK1_1	65	71	PF00069	0.402
MOD_CK2_1	216	222	PF00069	0.500
MOD_Cter_Amidation	79	82	PF01082	0.472
MOD_Cter_Amidation	91	94	PF01082	0.329
MOD_GlcNHglycan	139	142	PF01048	0.343
MOD_GlcNHglycan	192	195	PF01048	0.397
MOD_GlcNHglycan	64	67	PF01048	0.404
MOD_GSK3_1	170	177	PF00069	0.537
MOD_GSK3_1	285	292	PF00069	0.467
MOD_NEK2_1	106	111	PF00069	0.281
MOD_NEK2_1	174	179	PF00069	0.365
MOD_NEK2_1	213	218	PF00069	0.451
MOD_PIKK_1	117	123	PF00454	0.487
MOD_PIKK_1	183	189	PF00454	0.432
MOD_PIKK_1	216	222	PF00454	0.249
MOD_PK_1	107	113	PF00069	0.250
MOD_PK_1	246	252	PF00069	0.465
MOD_PKA_1	56	62	PF00069	0.432
MOD_PKA_2	106	112	PF00069	0.250
MOD_PKA_2	177	183	PF00069	0.370
MOD_PKA_2	21	27	PF00069	0.434
MOD_PKB_1	105	113	PF00069	0.249
MOD_PKB_1	54	62	PF00069	0.432
MOD_Plk_1	107	113	PF00069	0.269
MOD_Plk_4	14	20	PF00069	0.477
MOD_Plk_4	170	176	PF00069	0.427
MOD_Plk_4	177	183	PF00069	0.385
MOD_Plk_4	65	71	PF00069	0.387
MOD_ProDKin_1	144	150	PF00069	0.411
MOD_ProDKin_1	155	161	PF00069	0.493
TRG_DiLeu_BaLyEn_6	139	144	PF01217	0.283
TRG_DiLeu_BaLyEn_6	187	192	PF01217	0.417
TRG_ENDOCYTIC_2	205	208	PF00928	0.375
TRG_ER_diArg_1	175	178	PF00400	0.353
TRG_ER_diArg_1	228	230	PF00400	0.240
TRG_ER_diArg_1	93	95	PF00400	0.463
TRG_ER_diLys_1	294	298	PF00400	0.599
TRG_NLS_Bipartite_1	279	298	PF00514	0.471
TRG_NLS_Bipartite_1	35	57	PF00514	0.411
TRG_NLS_Bipartite_1	93	107	PF00514	0.610
TRG_NLS_MonoCore_2	52	57	PF00514	0.395
TRG_NLS_MonoExtC_3	102	107	PF00514	0.428
TRG_NLS_MonoExtC_3	52	57	PF00514	0.415
TRG_NLS_MonoExtN_4	53	59	PF00514	0.418
TRG_Pf-PMV_PEXEL_1	104	108	PF00026	0.491
TRG_Pf-PMV_PEXEL_1	240	245	PF00026	0.446
TRG_Pf-PMV_PEXEL_1	32	37	PF00026	0.404

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II54	Leptomonas seymouri	83%	100%
A0A0S4JDH9	Bodo saltans	67%	85%
A0A1X0P864	Trypanosomatidae	62%	90%
A0A3S7WUT2	Leishmania donovani	97%	100%
A0A422NWM7	Trypanosoma rangeli	74%	100%
A4H9C7	Leishmania braziliensis	91%	100%
A4HXP9	Leishmania infantum	97%	100%
D0A025	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	66%	100%
Q4QE19	Leishmania major	98%	100%
Q6BIF5	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	25%	100%
Q6FSN6	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	100%
Q75ET5	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	23%	100%
V5BRM0	Trypanosoma cruzi	72%	100%