Putative 60S ribosomal protein L7

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

60S ribosomal protein L7, putative

Species:

Leishmania mexicana

UniProt:

E9ARG0_LEIMU

TriTrypDb:

LmxM.18.0230

Length:

298

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0005840	ribosome	5	11
GO:0015934	large ribosomal subunit	4	1
GO:0022625	cytosolic large ribosomal subunit	5	1
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	12
GO:0043228	non-membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043232	intracellular non-membrane-bounded organelle	4	12
GO:0044391	ribosomal subunit	3	1

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Expansion

Sequence features

E9ARG0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARG0

Function

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Biological processes
Term	Name	Level	Count
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	1
GO:0000470	maturation of LSU-rRNA	9	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006364	rRNA processing	8	1
GO:0006396	RNA processing	6	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016070	RNA metabolic process	5	1

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003723	RNA binding	4	1
GO:0003735	structural constituent of ribosome	2	1
GO:0005198	structural molecule activity	1	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	130	132	PF00675	0.349
CLV_NRD_NRD_1	21	23	PF00675	0.459
CLV_NRD_NRD_1	229	231	PF00675	0.238
CLV_NRD_NRD_1	278	280	PF00675	0.427
CLV_NRD_NRD_1	294	296	PF00675	0.454
CLV_NRD_NRD_1	34	36	PF00675	0.409
CLV_NRD_NRD_1	42	44	PF00675	0.414
CLV_NRD_NRD_1	53	55	PF00675	0.514
CLV_NRD_NRD_1	74	76	PF00675	0.445
CLV_NRD_NRD_1	80	82	PF00675	0.420

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II54	Leptomonas seymouri	83%	100%
A0A0S4JDH9	Bodo saltans	67%	85%
A0A1X0P864	Trypanosomatidae	62%	90%
A0A3S7WUT2	Leishmania donovani	97%	100%
A0A422NWM7	Trypanosoma rangeli	74%	100%
A4H9C7	Leishmania braziliensis	91%	100%
A4HXP9	Leishmania infantum	97%	100%
D0A025	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	66%	100%
Q4QE19	Leishmania major	98%	100%
Q6BIF5	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	25%	100%

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