LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase a
Species:
Leishmania mexicana
UniProt:
E9ARD7_LEIMU
TriTrypDb:
LmxM.17.0200
Length:
1372

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 54
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 43, no: 28
NetGPI no yes: 0, no: 71
Cellular components
Term Name Level Count
GO:0110165 cellular anatomical entity 1 72
GO:0016020 membrane 2 67

Expansion

Sequence features

E9ARD7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 71
GO:0006163 purine nucleotide metabolic process 5 71
GO:0006164 purine nucleotide biosynthetic process 6 71
GO:0006171 cAMP biosynthetic process 8 71
GO:0006725 cellular aromatic compound metabolic process 3 71
GO:0006753 nucleoside phosphate metabolic process 4 71
GO:0006793 phosphorus metabolic process 3 71
GO:0006796 phosphate-containing compound metabolic process 4 71
GO:0006807 nitrogen compound metabolic process 2 71
GO:0007165 signal transduction 2 71
GO:0008152 metabolic process 1 71
GO:0009058 biosynthetic process 2 71
GO:0009117 nucleotide metabolic process 5 71
GO:0009150 purine ribonucleotide metabolic process 6 71
GO:0009152 purine ribonucleotide biosynthetic process 7 71
GO:0009165 nucleotide biosynthetic process 6 71
GO:0009187 cyclic nucleotide metabolic process 6 71
GO:0009190 cyclic nucleotide biosynthetic process 7 71
GO:0009259 ribonucleotide metabolic process 5 71
GO:0009260 ribonucleotide biosynthetic process 6 71
GO:0009987 cellular process 1 71
GO:0018130 heterocycle biosynthetic process 4 71
GO:0019438 aromatic compound biosynthetic process 4 71
GO:0019637 organophosphate metabolic process 3 71
GO:0019693 ribose phosphate metabolic process 4 71
GO:0034641 cellular nitrogen compound metabolic process 3 71
GO:0034654 nucleobase-containing compound biosynthetic process 4 71
GO:0035556 intracellular signal transduction 3 71
GO:0044237 cellular metabolic process 2 71
GO:0044238 primary metabolic process 2 71
GO:0044249 cellular biosynthetic process 3 71
GO:0044271 cellular nitrogen compound biosynthetic process 4 71
GO:0044281 small molecule metabolic process 2 71
GO:0046058 cAMP metabolic process 7 71
GO:0046390 ribose phosphate biosynthetic process 5 71
GO:0046483 heterocycle metabolic process 3 71
GO:0050789 regulation of biological process 2 71
GO:0050794 regulation of cellular process 3 71
GO:0052652 cyclic purine nucleotide metabolic process 6 71
GO:0055086 nucleobase-containing small molecule metabolic process 3 71
GO:0065007 biological regulation 1 71
GO:0071704 organic substance metabolic process 2 71
GO:0072521 purine-containing compound metabolic process 4 71
GO:0072522 purine-containing compound biosynthetic process 5 71
GO:0090407 organophosphate biosynthetic process 4 71
GO:1901135 carbohydrate derivative metabolic process 3 71
GO:1901137 carbohydrate derivative biosynthetic process 4 71
GO:1901293 nucleoside phosphate biosynthetic process 5 71
GO:1901360 organic cyclic compound metabolic process 3 71
GO:1901362 organic cyclic compound biosynthetic process 4 71
GO:1901564 organonitrogen compound metabolic process 3 71
GO:1901566 organonitrogen compound biosynthetic process 4 71
GO:1901576 organic substance biosynthetic process 3 71
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 62
GO:0016829 lyase activity 2 62
GO:0004016 adenylate cyclase activity 3 1
GO:0009975 cyclase activity 2 1
GO:0016849 phosphorus-oxygen lyase activity 3 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1251 1255 PF00656 0.718
CLV_C14_Caspase3-7 1339 1343 PF00656 0.781
CLV_C14_Caspase3-7 172 176 PF00656 0.459
CLV_C14_Caspase3-7 619 623 PF00656 0.450
CLV_C14_Caspase3-7 644 648 PF00656 0.420
CLV_C14_Caspase3-7 671 675 PF00656 0.385
CLV_C14_Caspase3-7 752 756 PF00656 0.429
CLV_C14_Caspase3-7 915 919 PF00656 0.550
CLV_C14_Caspase3-7 976 980 PF00656 0.502
CLV_MEL_PAP_1 1049 1055 PF00089 0.296
CLV_NRD_NRD_1 1016 1018 PF00675 0.232
CLV_NRD_NRD_1 1139 1141 PF00675 0.417
CLV_NRD_NRD_1 1307 1309 PF00675 0.535
CLV_NRD_NRD_1 1368 1370 PF00675 0.407
CLV_NRD_NRD_1 307 309 PF00675 0.569
CLV_NRD_NRD_1 600 602 PF00675 0.482
CLV_PCSK_KEX2_1 1139 1141 PF00082 0.417
CLV_PCSK_KEX2_1 1307 1309 PF00082 0.527
CLV_PCSK_KEX2_1 1368 1370 PF00082 0.403
CLV_PCSK_KEX2_1 307 309 PF00082 0.612
CLV_PCSK_KEX2_1 600 602 PF00082 0.510
CLV_PCSK_SKI1_1 101 105 PF00082 0.727
CLV_PCSK_SKI1_1 1297 1301 PF00082 0.549
CLV_PCSK_SKI1_1 131 135 PF00082 0.562
CLV_PCSK_SKI1_1 1368 1372 PF00082 0.396
CLV_PCSK_SKI1_1 189 193 PF00082 0.567
CLV_PCSK_SKI1_1 280 284 PF00082 0.538
CLV_PCSK_SKI1_1 300 304 PF00082 0.467
CLV_PCSK_SKI1_1 307 311 PF00082 0.493
CLV_PCSK_SKI1_1 544 548 PF00082 0.468
CLV_PCSK_SKI1_1 726 730 PF00082 0.501
CLV_PCSK_SKI1_1 803 807 PF00082 0.557
DEG_Nend_UBRbox_3 1 3 PF02207 0.494
DEG_SCF_FBW7_2 867 873 PF00400 0.558
DEG_SPOP_SBC_1 285 289 PF00917 0.455
DEG_SPOP_SBC_1 482 486 PF00917 0.360
DEG_SPOP_SBC_1 794 798 PF00917 0.444
DOC_ANK_TNKS_1 1279 1286 PF00023 0.579
DOC_CDC14_PxL_1 590 598 PF14671 0.383
DOC_CKS1_1 867 872 PF01111 0.506
DOC_CYCLIN_RxL_1 304 314 PF00134 0.270
DOC_CYCLIN_RxL_1 788 798 PF00134 0.318
DOC_CYCLIN_yCln2_LP_2 230 236 PF00134 0.368
DOC_MAPK_FxFP_2 487 490 PF00069 0.322
DOC_MAPK_gen_1 198 206 PF00069 0.313
DOC_MAPK_gen_1 26 34 PF00069 0.548
DOC_MAPK_gen_1 597 606 PF00069 0.287
DOC_MAPK_MEF2A_6 181 188 PF00069 0.365
DOC_MAPK_MEF2A_6 683 691 PF00069 0.446
DOC_MAPK_RevD_3 1126 1140 PF00069 0.558
DOC_PP1_RVXF_1 200 207 PF00149 0.246
DOC_PP1_RVXF_1 789 796 PF00149 0.210
DOC_PP4_FxxP_1 487 490 PF00568 0.509
DOC_PP4_FxxP_1 660 663 PF00568 0.443
DOC_PP4_FxxP_1 770 773 PF00568 0.286
DOC_SPAK_OSR1_1 433 437 PF12202 0.254
DOC_USP7_MATH_1 1011 1015 PF00917 0.620
DOC_USP7_MATH_1 285 289 PF00917 0.454
DOC_USP7_MATH_1 390 394 PF00917 0.264
DOC_USP7_MATH_1 483 487 PF00917 0.406
DOC_USP7_MATH_1 530 534 PF00917 0.365
DOC_USP7_MATH_1 542 546 PF00917 0.274
DOC_USP7_MATH_1 561 565 PF00917 0.320
DOC_USP7_MATH_1 663 667 PF00917 0.434
DOC_USP7_MATH_1 862 866 PF00917 0.441
DOC_USP7_MATH_1 984 988 PF00917 0.571
DOC_USP7_UBL2_3 701 705 PF12436 0.335
DOC_USP7_UBL2_3 80 84 PF12436 0.360
DOC_WW_Pin1_4 1074 1079 PF00397 0.548
DOC_WW_Pin1_4 1257 1262 PF00397 0.600
DOC_WW_Pin1_4 1283 1288 PF00397 0.689
DOC_WW_Pin1_4 1309 1314 PF00397 0.718
DOC_WW_Pin1_4 364 369 PF00397 0.550
DOC_WW_Pin1_4 585 590 PF00397 0.341
DOC_WW_Pin1_4 774 779 PF00397 0.351
DOC_WW_Pin1_4 863 868 PF00397 0.462
DOC_WW_Pin1_4 881 886 PF00397 0.362
LIG_14-3-3_CanoR_1 1036 1042 PF00244 0.631
LIG_14-3-3_CanoR_1 1218 1225 PF00244 0.670
LIG_14-3-3_CanoR_1 1236 1241 PF00244 0.590
LIG_14-3-3_CanoR_1 1318 1323 PF00244 0.727
LIG_14-3-3_CanoR_1 169 174 PF00244 0.435
LIG_14-3-3_CanoR_1 286 293 PF00244 0.419
LIG_14-3-3_CanoR_1 321 331 PF00244 0.466
LIG_14-3-3_CanoR_1 371 378 PF00244 0.602
LIG_14-3-3_CanoR_1 380 385 PF00244 0.502
LIG_14-3-3_CanoR_1 421 425 PF00244 0.350
LIG_14-3-3_CanoR_1 639 646 PF00244 0.376
LIG_14-3-3_CanoR_1 726 732 PF00244 0.429
LIG_14-3-3_CanoR_1 739 744 PF00244 0.459
LIG_14-3-3_CanoR_1 877 885 PF00244 0.537
LIG_Actin_WH2_2 1230 1248 PF00022 0.489
LIG_Actin_WH2_2 295 313 PF00022 0.388
LIG_Actin_WH2_2 711 728 PF00022 0.401
LIG_Actin_WH2_2 991 1006 PF00022 0.397
LIG_AP_GAE_1 250 256 PF02883 0.464
LIG_APCC_ABBA_1 136 141 PF00400 0.458
LIG_APCC_ABBA_1 718 723 PF00400 0.302
LIG_BIR_III_2 920 924 PF00653 0.655
LIG_BRCT_BRCA1_1 175 179 PF00533 0.392
LIG_BRCT_BRCA1_1 352 356 PF00533 0.304
LIG_BRCT_BRCA1_1 483 487 PF00533 0.435
LIG_BRCT_BRCA1_1 695 699 PF00533 0.448
LIG_BRCT_BRCA1_2 695 701 PF00533 0.225
LIG_Clathr_ClatBox_1 712 716 PF01394 0.208
LIG_deltaCOP1_diTrp_1 757 766 PF00928 0.429
LIG_DLG_GKlike_1 739 746 PF00625 0.288
LIG_FHA_1 1007 1013 PF00498 0.488
LIG_FHA_1 1032 1038 PF00498 0.513
LIG_FHA_1 1082 1088 PF00498 0.497
LIG_FHA_1 1273 1279 PF00498 0.705
LIG_FHA_1 143 149 PF00498 0.328
LIG_FHA_1 326 332 PF00498 0.339
LIG_FHA_1 413 419 PF00498 0.400
LIG_FHA_1 632 638 PF00498 0.413
LIG_FHA_1 657 663 PF00498 0.354
LIG_FHA_1 671 677 PF00498 0.381
LIG_FHA_1 680 686 PF00498 0.338
LIG_FHA_1 775 781 PF00498 0.399
LIG_FHA_1 794 800 PF00498 0.304
LIG_FHA_1 804 810 PF00498 0.405
LIG_FHA_1 903 909 PF00498 0.398
LIG_FHA_1 950 956 PF00498 0.554
LIG_FHA_1 998 1004 PF00498 0.576
LIG_FHA_2 1024 1030 PF00498 0.599
LIG_FHA_2 1144 1150 PF00498 0.727
LIG_FHA_2 1154 1160 PF00498 0.716
LIG_FHA_2 1172 1178 PF00498 0.574
LIG_FHA_2 1324 1330 PF00498 0.723
LIG_FHA_2 1348 1354 PF00498 0.704
LIG_FHA_2 170 176 PF00498 0.441
LIG_FHA_2 178 184 PF00498 0.446
LIG_FHA_2 381 387 PF00498 0.395
LIG_FHA_2 475 481 PF00498 0.429
LIG_FHA_2 71 77 PF00498 0.471
LIG_FHA_2 750 756 PF00498 0.274
LIG_FHA_2 796 802 PF00498 0.323
LIG_FHA_2 831 837 PF00498 0.430
LIG_FHA_2 933 939 PF00498 0.492
LIG_FHA_2 974 980 PF00498 0.495
LIG_GBD_Chelix_1 118 126 PF00786 0.668
LIG_GBD_Chelix_1 994 1002 PF00786 0.375
LIG_LIR_Apic_2 1028 1033 PF02991 0.494
LIG_LIR_Apic_2 444 448 PF02991 0.375
LIG_LIR_Apic_2 484 490 PF02991 0.507
LIG_LIR_Apic_2 588 594 PF02991 0.345
LIG_LIR_Apic_2 659 663 PF02991 0.449
LIG_LIR_Gen_1 1039 1049 PF02991 0.559
LIG_LIR_Gen_1 1061 1071 PF02991 0.595
LIG_LIR_Gen_1 238 248 PF02991 0.378
LIG_LIR_Gen_1 250 261 PF02991 0.355
LIG_LIR_Gen_1 477 487 PF02991 0.475
LIG_LIR_Gen_1 545 555 PF02991 0.369
LIG_LIR_Gen_1 696 704 PF02991 0.413
LIG_LIR_Gen_1 719 729 PF02991 0.299
LIG_LIR_Gen_1 931 942 PF02991 0.493
LIG_LIR_Nem_3 1013 1019 PF02991 0.493
LIG_LIR_Nem_3 1039 1045 PF02991 0.501
LIG_LIR_Nem_3 1061 1067 PF02991 0.515
LIG_LIR_Nem_3 1068 1074 PF02991 0.471
LIG_LIR_Nem_3 1097 1103 PF02991 0.515
LIG_LIR_Nem_3 1188 1193 PF02991 0.638
LIG_LIR_Nem_3 1295 1299 PF02991 0.753
LIG_LIR_Nem_3 238 244 PF02991 0.303
LIG_LIR_Nem_3 304 309 PF02991 0.397
LIG_LIR_Nem_3 353 359 PF02991 0.411
LIG_LIR_Nem_3 477 482 PF02991 0.376
LIG_LIR_Nem_3 545 550 PF02991 0.401
LIG_LIR_Nem_3 613 618 PF02991 0.342
LIG_LIR_Nem_3 696 702 PF02991 0.398
LIG_LIR_Nem_3 719 725 PF02991 0.302
LIG_LIR_Nem_3 757 763 PF02991 0.323
LIG_LIR_Nem_3 837 843 PF02991 0.465
LIG_LIR_Nem_3 931 937 PF02991 0.493
LIG_LIR_Nem_3 941 947 PF02991 0.607
LIG_LYPXL_yS_3 515 518 PF13949 0.433
LIG_MLH1_MIPbox_1 175 179 PF16413 0.408
LIG_MYND_3 607 611 PF01753 0.379
LIG_NRBOX 225 231 PF00104 0.267
LIG_PCNA_yPIPBox_3 128 136 PF02747 0.257
LIG_PCNA_yPIPBox_3 216 230 PF02747 0.266
LIG_PCNA_yPIPBox_3 299 311 PF02747 0.342
LIG_PCNA_yPIPBox_3 380 388 PF02747 0.305
LIG_Pex14_2 766 770 PF04695 0.281
LIG_PTB_Apo_2 63 70 PF02174 0.444
LIG_PTB_Apo_2 89 96 PF02174 0.259
LIG_PTB_Phospho_1 63 69 PF10480 0.453
LIG_PTB_Phospho_1 89 95 PF10480 0.259
LIG_SH2_CRK 237 241 PF00017 0.456
LIG_SH2_CRK 306 310 PF00017 0.448
LIG_SH2_CRK 445 449 PF00017 0.374
LIG_SH2_CRK 591 595 PF00017 0.248
LIG_SH2_GRB2like 810 813 PF00017 0.454
LIG_SH2_NCK_1 1064 1068 PF00017 0.595
LIG_SH2_NCK_1 237 241 PF00017 0.468
LIG_SH2_NCK_1 591 595 PF00017 0.239
LIG_SH2_NCK_1 618 622 PF00017 0.441
LIG_SH2_NCK_1 95 99 PF00017 0.451
LIG_SH2_PTP2 1030 1033 PF00017 0.537
LIG_SH2_PTP2 603 606 PF00017 0.462
LIG_SH2_SRC 1030 1033 PF00017 0.550
LIG_SH2_SRC 1064 1067 PF00017 0.595
LIG_SH2_SRC 139 142 PF00017 0.253
LIG_SH2_SRC 291 294 PF00017 0.436
LIG_SH2_SRC 810 813 PF00017 0.409
LIG_SH2_STAP1 1042 1046 PF00017 0.560
LIG_SH2_STAP1 566 570 PF00017 0.365
LIG_SH2_STAT3 461 464 PF00017 0.439
LIG_SH2_STAT3 91 94 PF00017 0.461
LIG_SH2_STAT5 1030 1033 PF00017 0.484
LIG_SH2_STAT5 1225 1228 PF00017 0.638
LIG_SH2_STAT5 139 142 PF00017 0.377
LIG_SH2_STAT5 178 181 PF00017 0.341
LIG_SH2_STAT5 194 197 PF00017 0.293
LIG_SH2_STAT5 221 224 PF00017 0.395
LIG_SH2_STAT5 237 240 PF00017 0.436
LIG_SH2_STAT5 291 294 PF00017 0.332
LIG_SH2_STAT5 349 352 PF00017 0.273
LIG_SH2_STAT5 382 385 PF00017 0.477
LIG_SH2_STAT5 440 443 PF00017 0.325
LIG_SH2_STAT5 461 464 PF00017 0.399
LIG_SH2_STAT5 603 606 PF00017 0.364
LIG_SH2_STAT5 615 618 PF00017 0.287
LIG_SH2_STAT5 63 66 PF00017 0.487
LIG_SH2_STAT5 810 813 PF00017 0.342
LIG_SH2_STAT5 911 914 PF00017 0.541
LIG_SH2_STAT5 95 98 PF00017 0.440
LIG_SH3_3 1208 1214 PF00018 0.610
LIG_SH3_3 1275 1281 PF00018 0.762
LIG_SH3_3 132 138 PF00018 0.347
LIG_SH3_3 568 574 PF00018 0.399
LIG_SH3_3 583 589 PF00018 0.347
LIG_SH3_3 856 862 PF00018 0.428
LIG_SH3_3 864 870 PF00018 0.457
LIG_Sin3_3 30 37 PF02671 0.522
LIG_SUMO_SIM_anti_2 1350 1359 PF11976 0.626
LIG_SUMO_SIM_anti_2 395 401 PF11976 0.325
LIG_SUMO_SIM_anti_2 506 512 PF11976 0.353
LIG_SUMO_SIM_anti_2 567 572 PF11976 0.455
LIG_SUMO_SIM_anti_2 846 852 PF11976 0.458
LIG_SUMO_SIM_anti_2 927 936 PF11976 0.495
LIG_SUMO_SIM_par_1 899 905 PF11976 0.437
LIG_TRAF2_1 1038 1041 PF00917 0.626
LIG_TRAF2_1 127 130 PF00917 0.426
LIG_TRAF2_1 383 386 PF00917 0.294
LIG_TRAF2_1 642 645 PF00917 0.254
LIG_TRFH_1 585 589 PF08558 0.265
LIG_TYR_ITIM 1062 1067 PF00017 0.479
LIG_TYR_ITIM 239 244 PF00017 0.535
LIG_TYR_ITIM 336 341 PF00017 0.491
LIG_TYR_ITIM 616 621 PF00017 0.465
LIG_TYR_ITIM 909 914 PF00017 0.320
LIG_UBA3_1 122 131 PF00899 0.474
LIG_UBA3_1 470 475 PF00899 0.593
LIG_WRC_WIRS_1 1322 1327 PF05994 0.407
LIG_WW_3 1213 1217 PF00397 0.607
MOD_CDK_SPxxK_3 364 371 PF00069 0.738
MOD_CDK_SPxxK_3 881 888 PF00069 0.599
MOD_CK1_1 1171 1177 PF00069 0.501
MOD_CK1_1 1321 1327 PF00069 0.658
MOD_CK1_1 325 331 PF00069 0.653
MOD_CK1_1 364 370 PF00069 0.676
MOD_CK1_1 478 484 PF00069 0.488
MOD_CK1_1 492 498 PF00069 0.453
MOD_CK1_1 564 570 PF00069 0.403
MOD_CK1_1 666 672 PF00069 0.453
MOD_CK1_1 70 76 PF00069 0.499
MOD_CK1_1 727 733 PF00069 0.375
MOD_CK1_1 742 748 PF00069 0.508
MOD_CK1_1 865 871 PF00069 0.683
MOD_CK1_1 93 99 PF00069 0.325
MOD_CK1_1 987 993 PF00069 0.506
MOD_CK2_1 1035 1041 PF00069 0.526
MOD_CK2_1 1101 1107 PF00069 0.349
MOD_CK2_1 1143 1149 PF00069 0.649
MOD_CK2_1 1153 1159 PF00069 0.606
MOD_CK2_1 1257 1263 PF00069 0.502
MOD_CK2_1 1321 1327 PF00069 0.705
MOD_CK2_1 1340 1346 PF00069 0.779
MOD_CK2_1 1347 1353 PF00069 0.749
MOD_CK2_1 177 183 PF00069 0.548
MOD_CK2_1 380 386 PF00069 0.507
MOD_CK2_1 534 540 PF00069 0.374
MOD_CK2_1 639 645 PF00069 0.419
MOD_CK2_1 795 801 PF00069 0.456
MOD_CK2_1 830 836 PF00069 0.443
MOD_CK2_1 843 849 PF00069 0.444
MOD_CK2_1 932 938 PF00069 0.337
MOD_Cter_Amidation 1137 1140 PF01082 0.506
MOD_GlcNHglycan 1013 1016 PF01048 0.496
MOD_GlcNHglycan 1136 1139 PF01048 0.463
MOD_GlcNHglycan 1162 1165 PF01048 0.600
MOD_GlcNHglycan 1329 1332 PF01048 0.717
MOD_GlcNHglycan 1346 1350 PF01048 0.544
MOD_GlcNHglycan 155 158 PF01048 0.537
MOD_GlcNHglycan 288 291 PF01048 0.515
MOD_GlcNHglycan 324 327 PF01048 0.692
MOD_GlcNHglycan 351 355 PF01048 0.358
MOD_GlcNHglycan 403 406 PF01048 0.504
MOD_GlcNHglycan 467 470 PF01048 0.520
MOD_GlcNHglycan 641 644 PF01048 0.435
MOD_GlcNHglycan 676 679 PF01048 0.419
MOD_GlcNHglycan 751 755 PF01048 0.567
MOD_GlcNHglycan 986 989 PF01048 0.448
MOD_GSK3_1 1031 1038 PF00069 0.505
MOD_GSK3_1 1153 1160 PF00069 0.524
MOD_GSK3_1 1167 1174 PF00069 0.590
MOD_GSK3_1 1214 1221 PF00069 0.626
MOD_GSK3_1 1236 1243 PF00069 0.315
MOD_GSK3_1 1253 1260 PF00069 0.408
MOD_GSK3_1 1303 1310 PF00069 0.606
MOD_GSK3_1 1323 1330 PF00069 0.703
MOD_GSK3_1 1336 1343 PF00069 0.766
MOD_GSK3_1 142 149 PF00069 0.397
MOD_GSK3_1 165 172 PF00069 0.416
MOD_GSK3_1 173 180 PF00069 0.469
MOD_GSK3_1 235 242 PF00069 0.442
MOD_GSK3_1 280 287 PF00069 0.483
MOD_GSK3_1 325 332 PF00069 0.626
MOD_GSK3_1 376 383 PF00069 0.641
MOD_GSK3_1 408 415 PF00069 0.358
MOD_GSK3_1 465 472 PF00069 0.566
MOD_GSK3_1 474 481 PF00069 0.554
MOD_GSK3_1 489 496 PF00069 0.451
MOD_GSK3_1 530 537 PF00069 0.392
MOD_GSK3_1 666 673 PF00069 0.468
MOD_GSK3_1 674 681 PF00069 0.444
MOD_GSK3_1 68 75 PF00069 0.461
MOD_GSK3_1 693 700 PF00069 0.361
MOD_GSK3_1 727 734 PF00069 0.505
MOD_GSK3_1 795 802 PF00069 0.454
MOD_GSK3_1 814 821 PF00069 0.383
MOD_GSK3_1 830 837 PF00069 0.374
MOD_GSK3_1 862 869 PF00069 0.582
MOD_GSK3_1 877 884 PF00069 0.548
MOD_GSK3_1 928 935 PF00069 0.354
MOD_GSK3_1 973 980 PF00069 0.352
MOD_N-GLC_1 1303 1308 PF02516 0.627
MOD_N-GLC_1 380 385 PF02516 0.412
MOD_N-GLC_1 419 424 PF02516 0.415
MOD_N-GLC_1 475 480 PF02516 0.556
MOD_N-GLC_1 564 569 PF02516 0.481
MOD_N-GLC_2 536 538 PF02516 0.253
MOD_NEK2_1 1168 1173 PF00069 0.535
MOD_NEK2_1 1303 1308 PF00069 0.696
MOD_NEK2_1 164 169 PF00069 0.483
MOD_NEK2_1 207 212 PF00069 0.458
MOD_NEK2_1 256 261 PF00069 0.400
MOD_NEK2_1 32 37 PF00069 0.422
MOD_NEK2_1 403 408 PF00069 0.396
MOD_NEK2_1 456 461 PF00069 0.465
MOD_NEK2_1 474 479 PF00069 0.370
MOD_NEK2_1 653 658 PF00069 0.401
MOD_NEK2_1 672 677 PF00069 0.293
MOD_NEK2_1 793 798 PF00069 0.421
MOD_NEK2_1 90 95 PF00069 0.356
MOD_NEK2_1 902 907 PF00069 0.367
MOD_NEK2_2 1253 1258 PF00069 0.406
MOD_NEK2_2 173 178 PF00069 0.525
MOD_NEK2_2 483 488 PF00069 0.477
MOD_NEK2_2 542 547 PF00069 0.445
MOD_PIKK_1 1238 1244 PF00454 0.625
MOD_PIKK_1 595 601 PF00454 0.539
MOD_PIKK_1 90 96 PF00454 0.271
MOD_PK_1 1307 1313 PF00069 0.414
MOD_PK_1 311 317 PF00069 0.289
MOD_PK_1 503 509 PF00069 0.246
MOD_PKA_1 1307 1313 PF00069 0.672
MOD_PKA_2 1035 1041 PF00069 0.529
MOD_PKA_2 1235 1241 PF00069 0.486
MOD_PKA_2 1307 1313 PF00069 0.704
MOD_PKA_2 1358 1364 PF00069 0.472
MOD_PKA_2 142 148 PF00069 0.506
MOD_PKA_2 207 213 PF00069 0.559
MOD_PKA_2 285 291 PF00069 0.509
MOD_PKA_2 3 9 PF00069 0.599
MOD_PKA_2 420 426 PF00069 0.395
MOD_PKB_1 1216 1224 PF00069 0.691
MOD_PKB_1 169 177 PF00069 0.267
MOD_PKB_1 875 883 PF00069 0.487
MOD_Plk_1 1341 1347 PF00069 0.790
MOD_Plk_1 217 223 PF00069 0.347
MOD_Plk_1 380 386 PF00069 0.354
MOD_Plk_1 419 425 PF00069 0.418
MOD_Plk_1 475 481 PF00069 0.505
MOD_Plk_1 564 570 PF00069 0.466
MOD_Plk_1 631 637 PF00069 0.532
MOD_Plk_1 716 722 PF00069 0.431
MOD_Plk_2-3 72 78 PF00069 0.344
MOD_Plk_2-3 973 979 PF00069 0.335
MOD_Plk_4 131 137 PF00069 0.484
MOD_Plk_4 173 179 PF00069 0.435
MOD_Plk_4 217 223 PF00069 0.503
MOD_Plk_4 225 231 PF00069 0.467
MOD_Plk_4 293 299 PF00069 0.409
MOD_Plk_4 403 409 PF00069 0.553
MOD_Plk_4 469 475 PF00069 0.502
MOD_Plk_4 503 509 PF00069 0.464
MOD_Plk_4 716 722 PF00069 0.473
MOD_Plk_4 776 782 PF00069 0.392
MOD_Plk_4 904 910 PF00069 0.356
MOD_Plk_4 928 934 PF00069 0.335
MOD_Plk_4 977 983 PF00069 0.349
MOD_ProDKin_1 1074 1080 PF00069 0.414
MOD_ProDKin_1 1257 1263 PF00069 0.488
MOD_ProDKin_1 1283 1289 PF00069 0.605
MOD_ProDKin_1 1309 1315 PF00069 0.652
MOD_ProDKin_1 364 370 PF00069 0.704
MOD_ProDKin_1 585 591 PF00069 0.405
MOD_ProDKin_1 774 780 PF00069 0.418
MOD_ProDKin_1 863 869 PF00069 0.577
MOD_ProDKin_1 881 887 PF00069 0.427
MOD_SUMO_rev_2 183 191 PF00179 0.526
MOD_SUMO_rev_2 72 82 PF00179 0.408
TRG_DiLeu_BaEn_1 60 65 PF01217 0.596
TRG_DiLeu_BaEn_1 928 933 PF01217 0.473
TRG_DiLeu_BaEn_4 1040 1046 PF01217 0.394
TRG_DiLeu_BaLyEn_6 305 310 PF01217 0.516
TRG_DiLeu_LyEn_5 1201 1206 PF01217 0.549
TRG_ENDOCYTIC_2 1016 1019 PF00928 0.343
TRG_ENDOCYTIC_2 1042 1045 PF00928 0.341
TRG_ENDOCYTIC_2 1064 1067 PF00928 0.473
TRG_ENDOCYTIC_2 241 244 PF00928 0.536
TRG_ENDOCYTIC_2 306 309 PF00928 0.526
TRG_ENDOCYTIC_2 338 341 PF00928 0.317
TRG_ENDOCYTIC_2 515 518 PF00928 0.426
TRG_ENDOCYTIC_2 603 606 PF00928 0.578
TRG_ENDOCYTIC_2 618 621 PF00928 0.495
TRG_ENDOCYTIC_2 722 725 PF00928 0.373
TRG_ENDOCYTIC_2 911 914 PF00928 0.473
TRG_ER_diArg_1 1049 1052 PF00400 0.337
TRG_ER_diArg_1 1215 1218 PF00400 0.620
TRG_ER_diArg_1 1244 1247 PF00400 0.578
TRG_ER_diArg_1 1279 1282 PF00400 0.769
TRG_ER_diArg_1 1307 1309 PF00400 0.482
TRG_ER_diArg_1 199 202 PF00400 0.480
TRG_ER_diArg_1 306 308 PF00400 0.432
TRG_ER_diArg_1 874 877 PF00400 0.638
TRG_NES_CRM1_1 334 345 PF08389 0.266
TRG_NES_CRM1_1 500 513 PF08389 0.369
TRG_Pf-PMV_PEXEL_1 960 964 PF00026 0.428

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 26% 100%
A0A1X0P171 Trypanosomatidae 33% 100%
A0A3Q8IJB0 Leishmania donovani 54% 100%
A0A3R7M6J4 Trypanosoma rangeli 37% 100%
A0A3R7R8G4 Trypanosoma rangeli 32% 100%
A0A3S5H6Z8 Leishmania donovani 54% 100%
A0A3S7WU91 Leishmania donovani 56% 97%
A0A3S7WU94 Leishmania donovani 84% 100%
A0A3S7WU95 Leishmania donovani 52% 98%
A4H8U6 Leishmania braziliensis 66% 100%
A4H8V5 Leishmania braziliensis 55% 100%
A4H8V7 Leishmania braziliensis 54% 100%
A4H8V8 Leishmania braziliensis 54% 100%
A4HPI4 Leishmania braziliensis 28% 100%
A4HX84 Leishmania infantum 84% 100%
A4HX85 Leishmania infantum 54% 98%
A4HX87 Leishmania infantum 56% 100%
A4HX88 Leishmania infantum 42% 100%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 57% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 99%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 55% 100%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 58% 100%
Q25263 Leishmania donovani 54% 100%
Q26721 Trypanosoma brucei brucei 33% 100%
Q27675 Leishmania donovani 84% 99%
Q4QEH9 Leishmania major 54% 100%
Q4QEI0 Leishmania major 54% 100%
Q4QEI1 Leishmania major 55% 100%
Q4QEI2 Leishmania major 55% 100%
Q4QEI3 Leishmania major 80% 100%
Q99279 Trypanosoma brucei brucei 29% 100%
Q99280 Trypanosoma brucei brucei 32% 100%
V5AYH7 Trypanosoma cruzi 34% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS