Putative ADP-ribosylation factor

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ADP-ribosylation factor, putative

Species:

Leishmania mexicana

UniProt:

E9ARC9_LEIMU

TriTrypDb:

LmxM.17.0070

Length:

187

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005794	Golgi apparatus	5	1
GO:0005802	trans-Golgi network	4	1
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0031984	organelle subcompartment	2	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1
GO:0097014	ciliary plasm	5	1
GO:0098791	Golgi apparatus subcompartment	3	1
GO:0099568	cytoplasmic region	3	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

E9ARC9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARC9

PDB structure(s): 2x77_A , 2x77_B

Function

Biological processes
Term	Name	Level	Count
GO:0006605	protein targeting	5	1
GO:0006622	protein targeting to lysosome	6	1
GO:0006623	protein targeting to vacuole	5	1
GO:0006810	transport	3	1
GO:0006886	intracellular protein transport	4	1
GO:0007034	vacuolar transport	4	1
GO:0007041	lysosomal transport	5	1
GO:0008104	protein localization	4	1
GO:0009987	cellular process	1	1
GO:0015031	protein transport	4	1
GO:0016192	vesicle-mediated transport	4	1
GO:0030100	regulation of endocytosis	5	1
GO:0032879	regulation of localization	3	1
GO:0033036	macromolecule localization	2	1
GO:0033365	protein localization to organelle	5	1
GO:0045184	establishment of protein localization	3	1
GO:0046907	intracellular transport	3	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0051049	regulation of transport	4	1
GO:0051128	regulation of cellular component organization	4	1
GO:0051179	localization	1	1
GO:0051234	establishment of localization	2	1
GO:0051641	cellular localization	2	1
GO:0051649	establishment of localization in cell	3	1
GO:0060627	regulation of vesicle-mediated transport	4	1
GO:0061462	protein localization to lysosome	7	1
GO:0065007	biological regulation	1	1
GO:0070727	cellular macromolecule localization	3	1
GO:0071702	organic substance transport	4	1
GO:0071705	nitrogen compound transport	4	1
GO:0072594	establishment of protein localization to organelle	4	1
GO:0072665	protein localization to vacuole	6	1
GO:0072666	establishment of protein localization to vacuole	5	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003824	catalytic activity	1	11
GO:0003924	GTPase activity	7	11
GO:0005488	binding	1	11
GO:0005525	GTP binding	5	11
GO:0016462	pyrophosphatase activity	5	11
GO:0016787	hydrolase activity	2	11
GO:0016817	hydrolase activity, acting on acid anhydrides	3	11
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	11
GO:0017076	purine nucleotide binding	4	11
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	11
GO:0019001	guanyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032561	guanyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	132	136	PF00656	0.338
CLV_C14_Caspase3-7	86	90	PF00656	0.246
CLV_NRD_NRD_1	119	121	PF00675	0.359
CLV_NRD_NRD_1	18	20	PF00675	0.324
CLV_PCSK_SKI1_1	121	125	PF00082	0.379
DEG_APCC_DBOX_1	119	127	PF00400	0.225
DEG_APCC_DBOX_1	38	46	PF00400	0.264
DEG_SPOP_SBC_1	159	163	PF00917	0.267
DOC_ANK_TNKS_1	180	187	PF00023	0.333
DOC_CYCLIN_RxL_1	19	29	PF00134	0.246
DOC_MAPK_gen_1	120	127	PF00069	0.379
DOC_MAPK_gen_1	19	28	PF00069	0.269
DOC_MAPK_MEF2A_6	120	127	PF00069	0.246
DOC_MAPK_MEF2A_6	19	28	PF00069	0.246
DOC_MAPK_NFAT4_5	120	128	PF00069	0.246
DOC_PP1_RVXF_1	60	67	PF00149	0.246
DOC_USP7_UBL2_3	160	164	PF12436	0.264
LIG_14-3-3_CanoR_1	120	124	PF00244	0.301
LIG_14-3-3_CanoR_1	82	92	PF00244	0.225
LIG_Actin_WH2_2	106	122	PF00022	0.246
LIG_FHA_1	153	159	PF00498	0.255
LIG_FHA_1	32	38	PF00498	0.246
LIG_FHA_1	49	55	PF00498	0.358
LIG_FHA_1	86	92	PF00498	0.267
LIG_FHA_1	9	15	PF00498	0.506
LIG_FHA_2	96	102	PF00498	0.301
LIG_LIR_Gen_1	109	119	PF02991	0.264
LIG_LIR_Nem_3	109	114	PF02991	0.264
LIG_LIR_Nem_3	155	159	PF02991	0.249
LIG_LIR_Nem_3	58	64	PF02991	0.279
LIG_NRBOX	109	115	PF00104	0.246
LIG_PDZ_Class_2	182	187	PF00595	0.403
LIG_Pex14_1	81	85	PF04695	0.246
LIG_PTB_Apo_2	60	67	PF02174	0.264
LIG_SH2_CRK	61	65	PF00017	0.264
LIG_SH2_STAT5	84	87	PF00017	0.251
LIG_SH2_STAT5	93	96	PF00017	0.246
LIG_SUMO_SIM_anti_2	122	127	PF11976	0.248
LIG_TYR_ITIM	59	64	PF00017	0.379
LIG_UBA3_1	123	130	PF00899	0.246
LIG_UBA3_1	24	33	PF00899	0.257
MOD_CK1_1	162	168	PF00069	0.280
MOD_CK2_1	135	141	PF00069	0.289
MOD_GSK3_1	154	161	PF00069	0.287
MOD_GSK3_1	4	11	PF00069	0.477
MOD_GSK3_1	44	51	PF00069	0.279
MOD_N-GLC_1	152	157	PF02516	0.327
MOD_N-GLC_1	62	67	PF02516	0.263
MOD_NEK2_1	119	124	PF00069	0.263
MOD_NEK2_1	146	151	PF00069	0.386
MOD_NEK2_1	152	157	PF00069	0.379
MOD_NEK2_1	8	13	PF00069	0.571
MOD_NEK2_2	4	9	PF00069	0.559
MOD_NMyristoyl	1	7	PF02799	0.433
MOD_PKA_2	119	125	PF00069	0.225
MOD_Plk_1	152	158	PF00069	0.324
MOD_Plk_1	62	68	PF00069	0.246
MOD_Plk_2-3	135	141	PF00069	0.379
MOD_Plk_4	119	125	PF00069	0.292
MOD_Plk_4	147	153	PF00069	0.399
MOD_Plk_4	32	38	PF00069	0.273
MOD_SUMO_for_1	106	109	PF00179	0.246
TRG_DiLeu_BaEn_1	109	114	PF01217	0.275
TRG_ENDOCYTIC_2	111	114	PF00928	0.289
TRG_ENDOCYTIC_2	61	64	PF00928	0.298

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3Q3	Leptomonas seymouri	42%	98%
A0A0N0P4P7	Leptomonas seymouri	34%	100%
A0A0N0P633	Leptomonas seymouri	50%	100%
A0A0N0P8D4	Leptomonas seymouri	44%	100%
A0A0N0P8G7	Leptomonas seymouri	23%	87%
A0A0N0P8Z3	Leptomonas seymouri	43%	100%
A0A0N1HS40	Leptomonas seymouri	48%	100%
A0A0N1HTN6	Leptomonas seymouri	92%	99%
A0A0N1I3A9	Leptomonas seymouri	40%	100%
A0A0N1I556	Leptomonas seymouri	53%	100%
A0A0N1I6N0	Leptomonas seymouri	44%	100%
A0A0N1IKF2	Leptomonas seymouri	31%	96%
A0A0N1IL60	Leptomonas seymouri	24%	90%
A0A0N1PD39	Leptomonas seymouri	39%	100%
A0A0S4IQT8	Bodo saltans	39%	100%
A0A0S4IS60	Bodo saltans	43%	100%
A0A0S4J2X3	Bodo saltans	46%	100%
A0A0S4J3L7	Bodo saltans	35%	100%
A0A0S4J5U8	Bodo saltans	31%	98%
A0A0S4J8H6	Bodo saltans	45%	100%
A0A0S4JK65	Bodo saltans	41%	100%
A0A0S4JQ13	Bodo saltans	35%	96%
A0A0S4JWF1	Bodo saltans	36%	66%
A0A0S4KJ70	Bodo saltans	54%	88%
A0A0S4KKS9	Bodo saltans	44%	100%
A0A0S4KLN8	Bodo saltans	25%	78%
A0A1X0NKM5	Trypanosomatidae	43%	100%
A0A1X0NKZ8	Trypanosomatidae	45%	96%
A0A1X0NLB1	Trypanosomatidae	45%	99%
A0A1X0NLP5	Trypanosomatidae	46%	100%
A0A1X0NT19	Trypanosomatidae	78%	98%
A0A1X0NZX3	Trypanosomatidae	46%	100%
A0A1X0P0A2	Trypanosomatidae	37%	100%
A0A1X0P0D4	Trypanosomatidae	34%	97%
A0A1X0P1Y5	Trypanosomatidae	35%	100%
A0A1X0P2L5	Trypanosomatidae	36%	96%
A0A1X0P5P0	Trypanosomatidae	51%	100%
A0A1X0P676	Trypanosomatidae	30%	98%
A0A1X0P850	Trypanosomatidae	27%	68%
A0A221LG87	Leishmania donovani	31%	96%
A0A3Q8IDS2	Leishmania donovani	34%	100%
A0A3Q8IFX9	Leishmania donovani	40%	100%
A0A3R7KSW8	Trypanosoma rangeli	35%	100%
A0A3R7L2X6	Trypanosoma rangeli	52%	100%
A0A3R7MW79	Trypanosoma rangeli	45%	99%
A0A3R7NC73	Trypanosoma rangeli	77%	98%
A0A3R7NMH3	Trypanosoma rangeli	31%	98%
A0A3R7RGT1	Trypanosoma rangeli	43%	100%
A0A3S5H598	Leishmania donovani	44%	100%
A0A3S5H5A9	Leishmania donovani	40%	98%
A0A3S5IQP0	Trypanosoma rangeli	44%	100%
A0A3S5ISB1	Trypanosoma rangeli	36%	100%
A0A3S7WU76	Leishmania donovani	98%	100%
A0A3S7X4X3	Leishmania donovani	52%	100%
A0A3S7X8N3	Leishmania donovani	44%	100%
A0A3S7XC57	Leishmania donovani	44%	100%
A0A422MYB1	Trypanosoma rangeli	51%	100%
A0A422MYF8	Trypanosoma rangeli	56%	100%
A0A422MZM4	Trypanosoma rangeli	34%	97%
A0A422NNC6	Trypanosoma rangeli	45%	97%
A0A422NRN0	Trypanosoma rangeli	47%	100%
A0A422NW53	Trypanosoma rangeli	39%	100%
A1CRG9	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	36%	99%
A1D4D1	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	36%	99%
A3LTA2	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	31%	98%
A4H3V3	Leishmania braziliensis	46%	100%
A4H3W8	Leishmania braziliensis	39%	100%
A4H449	Leishmania braziliensis	36%	100%
A4H8R6	Leishmania braziliensis	33%	100%
A4H8V3	Leishmania braziliensis	93%	100%
A4HH98	Leishmania braziliensis	43%	100%
A4HHR8	Leishmania braziliensis	24%	100%
A4HJL1	Leishmania braziliensis	49%	100%
A4HJR7	Leishmania braziliensis	53%	98%
A4HLP5	Leishmania braziliensis	24%	86%
A4HM52	Leishmania braziliensis	45%	100%
A4HQE3	Leishmania braziliensis	45%	100%
A4HS29	Leishmania infantum	44%	100%
A4HS43	Leishmania infantum	40%	98%
A4HSC6	Leishmania infantum	31%	96%
A4HX34	Leishmania infantum	34%	100%
A4HX72	Leishmania infantum	98%	100%
A4I4E4	Leishmania infantum	46%	100%
A4I5R5	Leishmania infantum	40%	100%
A4I784	Leishmania infantum	52%	100%
A4IAR4	Leishmania infantum	44%	100%
A4IE34	Leishmania infantum	44%	100%
A5DR82	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	31%	98%
A5E5G3	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	33%	98%
A6NH57	Homo sapiens	37%	100%
A8ISN6	Chlamydomonas reinhardtii	46%	100%
B5FYQ0	Taeniopygia guttata	47%	100%
B6DT76	Bodo saltans	26%	91%
C9ZL19	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	100%
C9ZPY6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	96%
C9ZR33	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZTU8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	75%	98%
C9ZVV9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	99%
C9ZY21	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	97%
C9ZY41	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	99%
C9ZZD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	52%	100%
C9ZZD6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
D0A2E8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
D0A2Q7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	69%
D0A3V1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	68%
E9ADU4	Leishmania major	44%	100%
E9AEJ0	Leishmania major	44%	100%
E9AHL7	Leishmania infantum	49%	100%
E9AIU0	Leishmania braziliensis	38%	100%
E9AK16	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	98%
E9AK30	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9AKA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9ALY6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9AQU9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	100%
E9AU58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9B110	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B229	Leishmania mexicana (strain MHOM/GT/2001/U1103)	49%	100%
E9B278	Leishmania mexicana (strain MHOM/GT/2001/U1103)	52%	98%
E9B420	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	86%
E9B5Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
F4IZ82	Arabidopsis thaliana	31%	100%
O00909	Dictyostelium discoideum	53%	100%
O04266	Brassica campestris	36%	97%
O04267	Brassica campestris	35%	96%
O04834	Arabidopsis thaliana	41%	97%
O08697	Rattus norvegicus	50%	100%
O23778	Catharanthus roseus	54%	100%
O45379	Caenorhabditis elegans	46%	100%
O48649	Salix bakko	56%	100%
O48920	Vigna unguiculata	55%	100%
O88848	Mus musculus	40%	100%
P0C583	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	38%	99%
P0C950	Aspergillus niger	35%	99%
P0C951	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	36%	99%
P0CM16	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	53%	100%
P0CM17	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	53%	100%
P0CR30	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	33%	99%
P0CR31	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	33%	99%
P0CT16	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	36%	99%
P0CT17	Magnaporthe oryzae (strain Y34)	36%	99%
P0DH91	Arabidopsis thaliana	55%	100%
P11076	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	55%	100%
P18085	Homo sapiens	49%	100%
P19146	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	54%	100%
P20606	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	98%
P22274	Candida albicans (strain SC5314 / ATCC MYA-2876)	54%	100%
P25160	Drosophila melanogaster	54%	100%
P26990	Gallus gallus	49%	100%
P26991	Giardia intestinalis	54%	98%
P34212	Caenorhabditis elegans	42%	100%
P34727	Ajellomyces capsulatus	57%	100%
P35292	Mus musculus	26%	87%
P36017	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	25%	89%
P36019	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	85%
P36397	Arabidopsis thaliana	55%	100%
P36404	Homo sapiens	50%	100%
P36405	Homo sapiens	47%	100%
P36536	Mus musculus	31%	94%
P36579	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	52%	100%
P37996	Rattus norvegicus	46%	100%
P38116	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	56%	100%
P39110	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	98%
P40616	Homo sapiens	61%	100%
P40617	Homo sapiens	38%	94%
P40940	Arabidopsis thaliana	59%	100%
P40945	Drosophila melanogaster	51%	100%
P40946	Drosophila melanogaster	52%	100%
P40994	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	47%	100%
P49076	Zea mays	56%	100%
P49702	Gallus gallus	50%	100%
P49703	Homo sapiens	39%	93%
P51643	Xenopus laevis	55%	100%
P51644	Xenopus laevis	50%	100%
P51645	Xenopus laevis	50%	100%
P51646	Rattus norvegicus	46%	100%
P51821	Chlamydomonas reinhardtii	54%	100%
P51822	Daucus carota	55%	100%
P51823	Oryza sativa subsp. japonica	55%	100%
P51824	Solanum tuberosum	54%	95%
P52884	Solanum lycopersicum	37%	97%
P56559	Homo sapiens	44%	97%
P61204	Homo sapiens	54%	100%
P61205	Mus musculus	54%	100%
P61206	Rattus norvegicus	54%	100%
P61207	Takifugu rubripes	54%	100%
P61208	Mus musculus	44%	97%
P61209	Drosophila melanogaster	56%	100%
P61210	Locusta migratoria	56%	100%
P61211	Mus musculus	61%	100%
P61212	Rattus norvegicus	61%	100%
P61213	Mus musculus	38%	94%
P61214	Rattus norvegicus	38%	94%
P61750	Mus musculus	49%	100%
P61751	Rattus norvegicus	49%	100%
P62330	Homo sapiens	49%	100%
P62331	Mus musculus	49%	100%
P62332	Rattus norvegicus	49%	100%
P78976	Hypocrea jecorina	43%	99%
P84077	Homo sapiens	55%	100%
P84078	Mus musculus	55%	100%
P84079	Rattus norvegicus	55%	100%
P84080	Bos taurus	55%	100%
P84081	Bos taurus	54%	100%
P84082	Rattus norvegicus	54%	100%
P84083	Rattus norvegicus	50%	100%
P84084	Mus musculus	50%	100%
P84085	Homo sapiens	50%	100%
P90726	Caenorhabditis briggsae	25%	93%
P91924	Dugesia japonica	53%	100%
Q007T5	Sus scrofa	49%	100%
Q01474	Arabidopsis thaliana	35%	97%
Q01475	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	98%
Q02804	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	34%	94%
Q06396	Oryza sativa subsp. japonica	55%	100%
Q06849	Drosophila melanogaster	44%	100%
Q09767	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	100%
Q0CUN7	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	36%	99%
Q0IIM2	Bos taurus	38%	100%
Q0P5N6	Homo sapiens	29%	95%
Q0UKC0	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	34%	100%
Q0VC18	Bos taurus	39%	94%
Q10943	Caenorhabditis elegans	55%	100%
Q13795	Homo sapiens	33%	93%
Q18510	Caenorhabditis elegans	34%	98%
Q19705	Caenorhabditis elegans	42%	100%
Q1MTE5	Danio rerio	47%	100%
Q1ZXA5	Dictyostelium discoideum	29%	100%
Q20758	Caenorhabditis elegans	56%	100%
Q23445	Caenorhabditis elegans	33%	97%
Q25761	Plasmodium falciparum (isolate NF54)	49%	100%
Q2HA55	Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970)	41%	98%
Q2KI07	Bos taurus	29%	100%
Q2KJ96	Bos taurus	46%	100%
Q2TA37	Bos taurus	50%	100%
Q2TBW6	Bos taurus	47%	100%
Q2YDM1	Bos taurus	61%	100%
Q32LJ2	Bos taurus	34%	93%
Q3SXC5	Mus musculus	36%	97%
Q3SZF2	Bos taurus	50%	100%
Q3T0D7	Bos taurus	30%	94%
Q3T0M9	Bos taurus	38%	94%
Q3T0T7	Bos taurus	30%	94%
Q4P0I7	Ustilago maydis (strain 521 / FGSC 9021)	33%	99%
Q4Q0D7	Leishmania major	43%	100%
Q4Q5Y0	Leishmania major	52%	98%
Q4Q756	Leishmania major	39%	100%
Q4QEJ1	Leishmania major	98%	100%
Q4QEM9	Leishmania major	32%	100%
Q4QJK0	Leishmania major	32%	100%
Q4R4S4	Macaca fascicularis	29%	100%
Q4R5P2	Macaca fascicularis	55%	100%
Q4WJS7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	36%	99%
Q52NJ3	Sus scrofa	30%	94%
Q52NJ4	Sus scrofa	47%	100%
Q54HK2	Dictyostelium discoideum	45%	98%
Q54I24	Dictyostelium discoideum	43%	87%
Q54JJ3	Dictyostelium discoideum	45%	99%
Q54K69	Dictyostelium discoideum	30%	95%
Q54R04	Dictyostelium discoideum	31%	100%
Q54UF1	Dictyostelium discoideum	46%	100%
Q54V41	Dictyostelium discoideum	44%	99%
Q54V47	Dictyostelium discoideum	46%	99%
Q54Y14	Dictyostelium discoideum	30%	96%
Q54YV7	Dictyostelium discoideum	25%	96%
Q559R0	Dictyostelium discoideum	34%	99%
Q55AD9	Dictyostelium discoideum	43%	100%
Q58DI9	Bos taurus	41%	100%
Q59S78	Candida albicans (strain SC5314 / ATCC MYA-2876)	33%	98%
Q5BGB9	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	35%	99%
Q5BK71	Rattus norvegicus	41%	100%
Q5E9I6	Bos taurus	54%	100%
Q5EA19	Bos taurus	29%	93%
Q5HZY2	Rattus norvegicus	30%	94%
Q5M9P8	Danio rerio	40%	100%
Q5PYH3	Sus scrofa	30%	94%
Q5R4G5	Pongo abelii	38%	100%
Q5R548	Pongo abelii	30%	94%
Q5R579	Pongo abelii	33%	93%
Q5R5P7	Pongo abelii	54%	100%
Q5R6E7	Pongo abelii	30%	100%
Q5RCF1	Pongo abelii	49%	100%
Q5RCQ6	Pongo abelii	37%	100%
Q5REU3	Pongo abelii	39%	93%
Q5RFN0	Pongo abelii	29%	92%
Q5VLR7	Leishmania donovani	49%	100%
Q5ZKQ8	Gallus gallus	30%	100%
Q60Z38	Caenorhabditis briggsae	35%	98%
Q61LA8	Caenorhabditis briggsae	54%	100%
Q627K4	Caenorhabditis briggsae	42%	100%
Q63055	Rattus norvegicus	33%	93%
Q66HA6	Rattus norvegicus	29%	100%
Q6BVA7	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	33%	98%
Q6CB54	Yarrowia lipolytica (strain CLIB 122 / E 150)	37%	98%
Q6CWR7	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	32%	98%
Q6FUZ9	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	34%	99%
Q6IMM3	Leishmania major	49%	100%
Q6NZW8	Danio rerio	29%	100%
Q6P068	Mus musculus	41%	100%
Q6P3A9	Mus musculus	39%	100%
Q6P8C8	Xenopus tropicalis	30%	100%
Q6T311	Homo sapiens	37%	100%
Q755D7	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	32%	98%
Q75A26	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	53%	100%
Q76NM7	Plasmodium falciparum (isolate 3D7)	26%	90%
Q7KQL3	Plasmodium falciparum (isolate 3D7)	49%	100%
Q7RVM2	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	54%	100%
Q80ZU0	Mus musculus	47%	100%
Q877B9	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	36%	99%
Q8BGR6	Mus musculus	29%	92%
Q8BSL7	Mus musculus	54%	100%
Q8BXL7	Mus musculus	33%	93%
Q8MQT8	Giardia intestinalis	29%	98%
Q8N4G2	Homo sapiens	38%	97%
Q8N8L6	Homo sapiens	36%	77%
Q8QHI3	Xenopus laevis	47%	100%
Q8SQH8	Encephalitozoon cuniculi (strain GB-M1)	36%	90%
Q8VEH3	Mus musculus	30%	100%
Q8VY57	Arabidopsis thaliana	32%	100%
Q8W4C8	Arabidopsis thaliana	35%	100%
Q93Y31	Arabidopsis thaliana	33%	100%
Q94231	Caenorhabditis elegans	48%	100%
Q94650	Plasmodium falciparum	49%	100%
Q96361	Brassica rapa subsp. pekinensis	59%	100%
Q969Q4	Homo sapiens	39%	95%
Q96BM9	Homo sapiens	30%	100%
Q96KC2	Homo sapiens	46%	100%
Q99PE9	Mus musculus	39%	93%
Q9CQC9	Mus musculus	30%	94%
Q9CQW2	Mus musculus	29%	100%
Q9D0J4	Mus musculus	50%	100%
Q9D4P0	Mus musculus	46%	100%
Q9H0F7	Homo sapiens	38%	100%
Q9H0T7	Homo sapiens	25%	88%
Q9LQC8	Arabidopsis thaliana	55%	100%
Q9N6B0	Leishmania donovani	46%	100%
Q9NR31	Homo sapiens	30%	94%
Q9NVJ2	Homo sapiens	29%	100%
Q9NXU5	Homo sapiens	29%	92%
Q9P4C8	Komagataella phaffii (strain GS115 / ATCC 20864)	34%	98%
Q9QVY3	Cricetulus griseus	30%	94%
Q9QXJ4	Mus musculus	37%	77%
Q9SHU5	Arabidopsis thaliana	49%	91%
Q9U0T6	Leishmania major	40%	100%
Q9VHV5	Drosophila melanogaster	31%	100%
Q9WUL7	Mus musculus	47%	100%
Q9XZX2	Leishmania major	45%	98%
Q9Y689	Homo sapiens	46%	100%
Q9Y6B6	Homo sapiens	30%	94%
Q9Y7Z2	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	100%
Q9ZPX1	Arabidopsis thaliana	47%	100%
V5B891	Trypanosoma cruzi	77%	98%
V5DJR8	Trypanosoma cruzi	44%	100%