Transmembrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania mexicana

UniProt:

E9ARA4_LEIMU

TriTrypDb:

LmxM.17.1315

Length:

415

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9ARA4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9ARA4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	165	167	PF00675	0.836
CLV_NRD_NRD_1	179	181	PF00675	0.651
CLV_NRD_NRD_1	394	396	PF00675	0.676
CLV_NRD_NRD_1	71	73	PF00675	0.824
CLV_NRD_NRD_1	99	101	PF00675	0.811
CLV_PCSK_FUR_1	163	167	PF00082	0.835
CLV_PCSK_KEX2_1	165	167	PF00082	0.836
CLV_PCSK_KEX2_1	179	181	PF00082	0.651
CLV_PCSK_KEX2_1	323	325	PF00082	0.615
CLV_PCSK_KEX2_1	354	356	PF00082	0.670
CLV_PCSK_KEX2_1	394	396	PF00082	0.676
CLV_PCSK_KEX2_1	71	73	PF00082	0.824
CLV_PCSK_PC1ET2_1	179	181	PF00082	0.826
CLV_PCSK_PC1ET2_1	323	325	PF00082	0.615
CLV_PCSK_PC1ET2_1	354	356	PF00082	0.670
CLV_PCSK_SKI1_1	2	6	PF00082	0.818
CLV_PCSK_SKI1_1	354	358	PF00082	0.667
CLV_PCSK_SKI1_1	56	60	PF00082	0.784
DEG_Nend_UBRbox_1	1	4	PF02207	0.627
DEG_ODPH_VHL_1	217	228	PF01847	0.638
DEG_SCF_FBW7_1	397	403	PF00400	0.846
DEG_SPOP_SBC_1	46	50	PF00917	0.608
DOC_ANK_TNKS_1	340	347	PF00023	0.871
DOC_CKS1_1	329	334	PF01111	0.859
DOC_CKS1_1	367	372	PF01111	0.857
DOC_CKS1_1	397	402	PF01111	0.849
DOC_CYCLIN_yClb3_PxF_3	106	112	PF00134	0.611
DOC_CYCLIN_yCln2_LP_2	104	110	PF00134	0.607
DOC_CYCLIN_yCln2_LP_2	199	205	PF00134	0.618
DOC_CYCLIN_yCln2_LP_2	207	213	PF00134	0.520
DOC_CYCLIN_yCln2_LP_2	226	232	PF00134	0.406
DOC_MAPK_DCC_7	78	87	PF00069	0.616
DOC_MAPK_MEF2A_6	301	310	PF00069	0.449
DOC_MAPK_RevD_3	308	324	PF00069	0.549
DOC_PP1_RVXF_1	54	60	PF00149	0.584
DOC_PP2B_LxvP_1	104	107	PF13499	0.604
DOC_PP2B_LxvP_1	205	208	PF13499	0.621
DOC_PP2B_LxvP_1	217	220	PF13499	0.479
DOC_PP2B_LxvP_1	226	229	PF13499	0.532
DOC_PP2B_LxvP_1	256	259	PF13499	0.651
DOC_PP2B_LxvP_1	365	368	PF13499	0.853
DOC_USP7_MATH_1	259	263	PF00917	0.644
DOC_USP7_MATH_1	46	50	PF00917	0.608
DOC_USP7_MATH_1	76	80	PF00917	0.623
DOC_WW_Pin1_4	10	15	PF00397	0.612
DOC_WW_Pin1_4	102	107	PF00397	0.605
DOC_WW_Pin1_4	140	145	PF00397	0.635
DOC_WW_Pin1_4	171	176	PF00397	0.627
DOC_WW_Pin1_4	198	203	PF00397	0.617
DOC_WW_Pin1_4	233	238	PF00397	0.645
DOC_WW_Pin1_4	243	248	PF00397	0.518
DOC_WW_Pin1_4	328	333	PF00397	0.854
DOC_WW_Pin1_4	340	345	PF00397	0.719
DOC_WW_Pin1_4	366	371	PF00397	0.853
DOC_WW_Pin1_4	396	401	PF00397	0.857
LIG_14-3-3_CanoR_1	100	105	PF00244	0.608
LIG_14-3-3_CanoR_1	227	237	PF00244	0.642
LIG_14-3-3_CanoR_1	339	344	PF00244	0.870
LIG_BRCT_BRCA1_1	266	270	PF00533	0.640
LIG_CtBP_PxDLS_1	129	133	PF00389	0.635
LIG_EH1_1	310	318	PF00400	0.549
LIG_EVH1_1	22	26	PF00568	0.620
LIG_EVH1_2	109	113	PF00568	0.616
LIG_EVH1_2	144	148	PF00568	0.637
LIG_FHA_1	255	261	PF00498	0.648
LIG_FHA_1	379	385	PF00498	0.871
LIG_FHA_1	46	52	PF00498	0.603
LIG_FHA_2	239	245	PF00498	0.649
LIG_IRF3_LxIS_1	404	410	PF10401	0.819
LIG_LIR_Gen_1	401	412	PF02991	0.819
LIG_LIR_Nem_3	119	125	PF02991	0.626
LIG_LIR_Nem_3	298	303	PF02991	0.627
LIG_LIR_Nem_3	401	407	PF02991	0.827
LIG_MYND_1	106	110	PF01753	0.608
LIG_PDZ_Class_1	410	415	PF00595	0.809
LIG_REV1ctd_RIR_1	319	328	PF16727	0.776
LIG_SH2_STAT5	177	180	PF00017	0.625
LIG_SH2_STAT5	182	185	PF00017	0.560
LIG_SH2_STAT5	28	31	PF00017	0.632
LIG_SH3_1	301	307	PF00018	0.449
LIG_SH3_3	103	109	PF00018	0.607
LIG_SH3_3	183	189	PF00018	0.621
LIG_SH3_3	20	26	PF00018	0.621
LIG_SH3_3	206	212	PF00018	0.619
LIG_SH3_3	244	250	PF00018	0.640
LIG_SH3_3	263	269	PF00018	0.401
LIG_SH3_3	301	307	PF00018	0.449
LIG_SH3_3	326	332	PF00018	0.843
LIG_SH3_3	35	41	PF00018	0.464
LIG_SH3_3	361	367	PF00018	0.859
LIG_SH3_3	381	387	PF00018	0.623
LIG_SUMO_SIM_anti_2	312	318	PF11976	0.549
LIG_SUMO_SIM_anti_2	403	410	PF11976	0.820
LIG_SUMO_SIM_par_1	128	134	PF11976	0.636
LIG_SUMO_SIM_par_1	312	318	PF11976	0.549
LIG_TRFH_1	59	63	PF08558	0.580
LIG_UBA3_1	316	323	PF00899	0.549
LIG_WW_1	25	28	PF00397	0.624
LIG_WW_2	106	109	PF00397	0.607
LIG_WW_2	209	212	PF00397	0.618
MOD_CDK_SPK_2	328	333	PF00069	0.854
MOD_CDK_SPxxK_3	340	347	PF00069	0.871
MOD_CK1_1	116	122	PF00069	0.620
MOD_CK1_1	246	252	PF00069	0.638
MOD_CK1_1	295	301	PF00069	0.631
MOD_CK1_1	7	13	PF00069	0.615
MOD_CK2_1	128	134	PF00069	0.636
MOD_CK2_1	238	244	PF00069	0.651
MOD_CK2_1	339	345	PF00069	0.870
MOD_CK2_1	374	380	PF00069	0.871
MOD_DYRK1A_RPxSP_1	171	175	PF00069	0.626
MOD_GlcNHglycan	125	128	PF01048	0.834
MOD_GlcNHglycan	140	143	PF01048	0.655
MOD_GlcNHglycan	17	20	PF01048	0.823
MOD_GSK3_1	140	147	PF00069	0.638
MOD_GSK3_1	171	178	PF00069	0.626
MOD_GSK3_1	260	267	PF00069	0.641
MOD_GSK3_1	286	293	PF00069	0.652
MOD_GSK3_1	374	381	PF00069	0.872
MOD_GSK3_1	396	403	PF00069	0.850
MOD_GSK3_1	6	13	PF00069	0.614
MOD_GSK3_1	70	77	PF00069	0.622
MOD_GSK3_1	90	97	PF00069	0.359
MOD_LATS_1	43	49	PF00433	0.624
MOD_NEK2_1	113	118	PF00069	0.619
MOD_NEK2_1	15	20	PF00069	0.622
MOD_NEK2_1	213	218	PF00069	0.630
MOD_NEK2_1	291	296	PF00069	0.645
MOD_NEK2_1	315	320	PF00069	0.549
MOD_NEK2_1	407	412	PF00069	0.810
MOD_PIKK_1	116	122	PF00454	0.620
MOD_PIKK_1	260	266	PF00454	0.641
MOD_PIKK_1	85	91	PF00454	0.610
MOD_PKA_1	100	106	PF00069	0.607
MOD_PKA_1	354	360	PF00069	0.867
MOD_PKA_1	71	77	PF00069	0.623
MOD_PKA_2	286	292	PF00069	0.652
MOD_PKA_2	354	360	PF00069	0.867
MOD_PKA_2	378	384	PF00069	0.872
MOD_PKA_2	70	76	PF00069	0.623
MOD_Plk_1	46	52	PF00069	0.603
MOD_Plk_4	400	406	PF00069	0.832
MOD_ProDKin_1	10	16	PF00069	0.613
MOD_ProDKin_1	102	108	PF00069	0.606
MOD_ProDKin_1	140	146	PF00069	0.637
MOD_ProDKin_1	171	177	PF00069	0.626
MOD_ProDKin_1	198	204	PF00069	0.618
MOD_ProDKin_1	233	239	PF00069	0.646
MOD_ProDKin_1	243	249	PF00069	0.518
MOD_ProDKin_1	328	334	PF00069	0.856
MOD_ProDKin_1	340	346	PF00069	0.721
MOD_ProDKin_1	366	372	PF00069	0.856
MOD_ProDKin_1	396	402	PF00069	0.853
TRG_DiLeu_BaLyEn_6	157	162	PF01217	0.636
TRG_DiLeu_BaLyEn_6	199	204	PF01217	0.617
TRG_DiLeu_BaLyEn_6	209	214	PF01217	0.496
TRG_ER_diArg_1	162	165	PF00400	0.637
TRG_NLS_Bipartite_1	165	183	PF00514	0.629