LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AR99_LEIMU
TriTrypDb:
LmxM.17.1270
Length:
317

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AR99
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AR99

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0005488 binding 1 7
GO:0051536 iron-sulfur cluster binding 3 7
GO:0051540 metal cluster binding 2 7
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 141 145 PF00656 0.462
CLV_C14_Caspase3-7 221 225 PF00656 0.464
CLV_NRD_NRD_1 301 303 PF00675 0.571
CLV_NRD_NRD_1 49 51 PF00675 0.762
CLV_NRD_NRD_1 81 83 PF00675 0.586
CLV_NRD_NRD_1 93 95 PF00675 0.546
CLV_PCSK_FUR_1 258 262 PF00082 0.681
CLV_PCSK_KEX2_1 260 262 PF00082 0.671
CLV_PCSK_KEX2_1 28 30 PF00082 0.651
CLV_PCSK_KEX2_1 301 303 PF00082 0.571
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PDS7 Leptomonas seymouri 85% 100%
A0A0S4JAC0 Bodo saltans 67% 100%
A0A1X0NSZ4 Trypanosomatidae 82% 100%
A0A3Q8IAU8 Leishmania donovani 96% 100%
A4H986 Leishmania braziliensis 94% 100%
A4HXK4 Leishmania infantum 96% 100%
C9ZP94 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 81% 98%
Q4QE64 Leishmania major 96% 100%
V5BET1 Trypanosoma cruzi 83% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS