LeishMANIAdb
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Putative kinesin

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative kinesin
Gene product:
kinesin, putative
Species:
Leishmania mexicana
UniProt:
E9AR83_LEIMU
TriTrypDb:
LmxM.17.1110
Length:
1430

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 3
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005871 kinesin complex 3 1
GO:0005874 microtubule 6 1
GO:0005875 microtubule associated complex 2 1
GO:0005930 axoneme 2 1
GO:0032991 protein-containing complex 1 1
GO:0097542 ciliary tip 2 1
GO:0099080 supramolecular complex 2 1
GO:0099081 supramolecular polymer 3 1
GO:0099512 supramolecular fiber 4 1
GO:0099513 polymeric cytoskeletal fiber 5 1
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Expansion

Sequence features

E9AR83
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
TermNameLevelCount
GO:0006810 transport 3 1
GO:0007017 microtubule-based process 2 12
GO:0007018 microtubule-based movement 3 12
GO:0009987 cellular process 1 12
GO:0030705 cytoskeleton-dependent intracellular transport 4 1
GO:0046907 intracellular transport 3 1
GO:0051179 localization 1 1
GO:0051234 establishment of localization 2 1
GO:0051641 cellular localization 2 1
GO:0051649 establishment of localization in cell 3 1
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Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 12
GO:0003774 cytoskeletal motor activity 1 12
GO:0003777 microtubule motor activity 2 12
GO:0003824 catalytic activity 1 4
GO:0005488 binding 1 12
GO:0005515 protein binding 2 12
GO:0005524 ATP binding 5 12
GO:0008017 microtubule binding 5 12
GO:0008092 cytoskeletal protein binding 3 12
GO:0008574 plus-end-directed microtubule motor activity 3 1
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1173 1177 PF00656 0.665
CLV_C14_Caspase3-7 1184 1188 PF00656 0.593
CLV_C14_Caspase3-7 1252 1256 PF00656 0.710
CLV_C14_Caspase3-7 22 26 PF00656 0.398
CLV_C14_Caspase3-7 567 571 PF00656 0.482
CLV_C14_Caspase3-7 736 740 PF00656 0.499
CLV_NRD_NRD_1 1068 1070 PF00675 0.291
CLV_NRD_NRD_1 1137 1139 PF00675 0.522
CLV_NRD_NRD_1 1257 1259 PF00675 0.719
CLV_NRD_NRD_1 1271 1273 PF00675 0.560
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IA24 Leptomonas seymouri 72% 99%
A0A0S4J9L3 Bodo saltans 58% 100%
A0A1X0NT18 Trypanosomatidae 61% 100%
A0A3S7WUM6 Leishmania donovani 93% 100%
A0A422NS23 Trypanosoma rangeli 65% 100%
A4H966 Leishmania braziliensis 84% 100%
A4HXI8 Leishmania infantum 93% 100%
C9ZP76 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 65% 100%
Q4QE80 Leishmania major 92% 100%
V5DFN8 Trypanosoma cruzi 61% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS