Uncharacterized protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA-binding protein, putative

Species:

Leishmania mexicana

UniProt:

E9AR53_LEIMU

TriTrypDb:

LmxM.17.0810

Length:

379

Annotations

LeishMANIAdb annotations

A Kinetoplastid-specific protein. Unlikely to be a membrane protein.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AR53

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AR53

Function

Could not find GO biological_process term for this entry.

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	3
GO:0005488	binding	1	3
GO:0097159	organic cyclic compound binding	2	3
GO:1901363	heterocyclic compound binding	2	3

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	17	21	PF00656	0.444
CLV_C14_Caspase3-7	188	192	PF00656	0.413
CLV_C14_Caspase3-7	262	266	PF00656	0.540
CLV_NRD_NRD_1	10	12	PF00675	0.422
CLV_NRD_NRD_1	182	184	PF00675	0.442
CLV_NRD_NRD_1	241	243	PF00675	0.364
CLV_NRD_NRD_1	277	279	PF00675	0.571
CLV_NRD_NRD_1	52	54	PF00675	0.602
CLV_PCSK_KEX2_1	10	12	PF00082	0.422
CLV_PCSK_KEX2_1	182	184	PF00082	0.577

Previous1 2 3 4 5…11Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKU0	Leptomonas seymouri	42%	73%
A0A1X0NT51	Trypanosomatidae	27%	76%
A0A3Q8ICU3	Leishmania donovani	92%	100%
A0A3R7JY32	Trypanosoma rangeli	29%	83%
A4H944	Leishmania braziliensis	79%	100%
C9ZP32	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	82%
Q4QEB0	Leishmania major	88%	100%
V5B6D3	Trypanosoma cruzi	29%	80%

Previous1Next