Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AR01_LEIMU

TriTrypDb:

LmxM.17.0320

Length:

299

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AR01

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AR01

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	126	130	PF00656	0.636
CLV_C14_Caspase3-7	233	237	PF00656	0.532
CLV_NRD_NRD_1	281	283	PF00675	0.552
CLV_NRD_NRD_1	3	5	PF00675	0.591
CLV_NRD_NRD_1	43	45	PF00675	0.412
CLV_PCSK_FUR_1	276	280	PF00082	0.608
CLV_PCSK_FUR_1	47	51	PF00082	0.571
CLV_PCSK_KEX2_1	278	280	PF00082	0.772
CLV_PCSK_KEX2_1	281	283	PF00082	0.547
CLV_PCSK_KEX2_1	3	5	PF00082	0.591
CLV_PCSK_KEX2_1	49	51	PF00082	0.563
CLV_PCSK_PC1ET2_1	49	51	PF00082	0.563
CLV_PCSK_PC7_1	276	282	PF00082	0.693
CLV_PCSK_SKI1_1	20	24	PF00082	0.560
CLV_PCSK_SKI1_1	84	88	PF00082	0.448
DEG_APCC_DBOX_1	49	57	PF00400	0.277
DEG_APCC_KENBOX_2	65	69	PF00400	0.297
DOC_MAPK_gen_1	278	287	PF00069	0.618
DOC_MAPK_gen_1	47	56	PF00069	0.413
DOC_SPAK_OSR1_1	32	36	PF12202	0.417
DOC_USP7_MATH_1	131	135	PF00917	0.605
DOC_USP7_MATH_1	197	201	PF00917	0.529
DOC_USP7_UBL2_3	45	49	PF12436	0.398
DOC_WW_Pin1_4	187	192	PF00397	0.628
DOC_WW_Pin1_4	20	25	PF00397	0.738
DOC_WW_Pin1_4	207	212	PF00397	0.614
LIG_14-3-3_CanoR_1	182	186	PF00244	0.606
LIG_14-3-3_CanoR_1	279	287	PF00244	0.555
LIG_BIR_II_1	1	5	PF00653	0.534
LIG_BIR_III_4	129	133	PF00653	0.553
LIG_FHA_2	210	216	PF00498	0.711
LIG_FHA_2	231	237	PF00498	0.488
LIG_LIR_Gen_1	31	37	PF02991	0.413
LIG_LIR_Nem_3	31	36	PF02991	0.415
LIG_Pex14_2	33	37	PF04695	0.411
LIG_Rb_pABgroove_1	58	66	PF01858	0.440
LIG_SH2_SRC	124	127	PF00017	0.627
LIG_SH2_STAP1	124	128	PF00017	0.573
LIG_SH3_3	205	211	PF00018	0.788
LIG_SH3_3	244	250	PF00018	0.686
LIG_SH3_CIN85_PxpxPR_1	251	256	PF14604	0.611
LIG_TRAF2_1	123	126	PF00917	0.677
LIG_TRFH_1	183	187	PF08558	0.563
LIG_WRC_WIRS_1	143	148	PF05994	0.466
MOD_CDK_SPxxK_3	20	27	PF00069	0.559
MOD_CK1_1	150	156	PF00069	0.615
MOD_CK1_1	159	165	PF00069	0.611
MOD_CK1_1	200	206	PF00069	0.620
MOD_CK1_1	209	215	PF00069	0.725
MOD_CK1_1	237	243	PF00069	0.621
MOD_CK1_1	264	270	PF00069	0.606
MOD_CK1_1	283	289	PF00069	0.585
MOD_CK2_1	209	215	PF00069	0.712
MOD_GlcNHglycan	158	161	PF01048	0.666
MOD_GlcNHglycan	282	285	PF01048	0.464
MOD_GlcNHglycan	40	43	PF01048	0.476
MOD_GSK3_1	147	154	PF00069	0.595
MOD_GSK3_1	155	162	PF00069	0.608
MOD_GSK3_1	16	23	PF00069	0.648
MOD_GSK3_1	193	200	PF00069	0.652
MOD_GSK3_1	230	237	PF00069	0.614
MOD_N-GLC_2	105	107	PF02516	0.378
MOD_PKA_1	280	286	PF00069	0.655
MOD_PKA_2	181	187	PF00069	0.644
MOD_PKA_2	280	286	PF00069	0.568
MOD_PKA_2	38	44	PF00069	0.483
MOD_PKB_1	278	286	PF00069	0.669
MOD_Plk_1	58	64	PF00069	0.384
MOD_ProDKin_1	187	193	PF00069	0.629
MOD_ProDKin_1	20	26	PF00069	0.735
MOD_ProDKin_1	207	213	PF00069	0.612
MOD_SUMO_for_1	48	51	PF00179	0.565
TRG_DiLeu_BaEn_4	114	120	PF01217	0.425
TRG_ER_diArg_1	276	279	PF00400	0.721
TRG_ER_diArg_1	280	282	PF00400	0.633
TRG_ER_diArg_1	73	76	PF00400	0.303

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I9Y1	Leptomonas seymouri	36%	93%
A0A3S7WUB2	Leishmania donovani	81%	91%
A4H8X5	Leishmania braziliensis	65%	100%
A4HX99	Leishmania infantum	83%	91%
Q4QEG2	Leishmania major	80%	100%