LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase b
Species:
Leishmania mexicana
UniProt:
E9AQY4_LEIMU
TriTrypDb:
LmxM.17.0237
Length:
1330

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 60
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 47, no: 29
NetGPI no yes: 0, no: 76
Cellular components
Term Name Level Count
GO:0016020 membrane 2 71
GO:0110165 cellular anatomical entity 1 77

Expansion

Sequence features

E9AQY4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 76
GO:0006163 purine nucleotide metabolic process 5 76
GO:0006164 purine nucleotide biosynthetic process 6 76
GO:0006171 cAMP biosynthetic process 8 76
GO:0006725 cellular aromatic compound metabolic process 3 76
GO:0006753 nucleoside phosphate metabolic process 4 76
GO:0006793 phosphorus metabolic process 3 76
GO:0006796 phosphate-containing compound metabolic process 4 76
GO:0006807 nitrogen compound metabolic process 2 76
GO:0007165 signal transduction 2 76
GO:0008152 metabolic process 1 76
GO:0009058 biosynthetic process 2 76
GO:0009117 nucleotide metabolic process 5 76
GO:0009150 purine ribonucleotide metabolic process 6 76
GO:0009152 purine ribonucleotide biosynthetic process 7 76
GO:0009165 nucleotide biosynthetic process 6 76
GO:0009187 cyclic nucleotide metabolic process 6 76
GO:0009190 cyclic nucleotide biosynthetic process 7 76
GO:0009259 ribonucleotide metabolic process 5 76
GO:0009260 ribonucleotide biosynthetic process 6 76
GO:0009987 cellular process 1 76
GO:0018130 heterocycle biosynthetic process 4 76
GO:0019438 aromatic compound biosynthetic process 4 76
GO:0019637 organophosphate metabolic process 3 76
GO:0019693 ribose phosphate metabolic process 4 76
GO:0034641 cellular nitrogen compound metabolic process 3 76
GO:0034654 nucleobase-containing compound biosynthetic process 4 76
GO:0035556 intracellular signal transduction 3 76
GO:0044237 cellular metabolic process 2 76
GO:0044238 primary metabolic process 2 76
GO:0044249 cellular biosynthetic process 3 76
GO:0044271 cellular nitrogen compound biosynthetic process 4 76
GO:0044281 small molecule metabolic process 2 76
GO:0046058 cAMP metabolic process 7 76
GO:0046390 ribose phosphate biosynthetic process 5 76
GO:0046483 heterocycle metabolic process 3 76
GO:0050789 regulation of biological process 2 76
GO:0050794 regulation of cellular process 3 76
GO:0052652 cyclic purine nucleotide metabolic process 6 76
GO:0055086 nucleobase-containing small molecule metabolic process 3 76
GO:0065007 biological regulation 1 76
GO:0071704 organic substance metabolic process 2 76
GO:0072521 purine-containing compound metabolic process 4 76
GO:0072522 purine-containing compound biosynthetic process 5 76
GO:0090407 organophosphate biosynthetic process 4 76
GO:1901135 carbohydrate derivative metabolic process 3 76
GO:1901137 carbohydrate derivative biosynthetic process 4 76
GO:1901293 nucleoside phosphate biosynthetic process 5 76
GO:1901360 organic cyclic compound metabolic process 3 76
GO:1901362 organic cyclic compound biosynthetic process 4 76
GO:1901564 organonitrogen compound metabolic process 3 76
GO:1901566 organonitrogen compound biosynthetic process 4 76
GO:1901576 organic substance biosynthetic process 3 76
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 64
GO:0016829 lyase activity 2 64
GO:0004016 adenylate cyclase activity 3 1
GO:0009975 cyclase activity 2 1
GO:0016849 phosphorus-oxygen lyase activity 3 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 359 363 PF00656 0.333
CLV_C14_Caspase3-7 386 390 PF00656 0.464
CLV_C14_Caspase3-7 636 640 PF00656 0.424
CLV_C14_Caspase3-7 806 810 PF00656 0.318
CLV_C14_Caspase3-7 923 927 PF00656 0.570
CLV_C14_Caspase3-7 984 988 PF00656 0.507
CLV_MEL_PAP_1 1057 1063 PF00089 0.299
CLV_NRD_NRD_1 1147 1149 PF00675 0.411
CLV_NRD_NRD_1 1314 1316 PF00675 0.548
CLV_NRD_NRD_1 207 209 PF00675 0.607
CLV_NRD_NRD_1 432 434 PF00675 0.461
CLV_NRD_NRD_1 691 693 PF00675 0.618
CLV_NRD_NRD_1 802 804 PF00675 0.639
CLV_NRD_NRD_1 9 11 PF00675 0.653
CLV_PCSK_FUR_1 205 209 PF00082 0.607
CLV_PCSK_KEX2_1 1147 1149 PF00082 0.411
CLV_PCSK_KEX2_1 207 209 PF00082 0.607
CLV_PCSK_KEX2_1 690 692 PF00082 0.560
CLV_PCSK_KEX2_1 802 804 PF00082 0.651
CLV_PCSK_KEX2_1 9 11 PF00082 0.501
CLV_PCSK_SKI1_1 128 132 PF00082 0.560
CLV_PCSK_SKI1_1 208 212 PF00082 0.601
CLV_PCSK_SKI1_1 255 259 PF00082 0.577
CLV_PCSK_SKI1_1 434 438 PF00082 0.433
CLV_PCSK_SKI1_1 633 637 PF00082 0.511
CLV_PCSK_SKI1_1 747 751 PF00082 0.541
CLV_PCSK_SKI1_1 802 806 PF00082 0.601
CLV_Separin_Metazoa 606 610 PF03568 0.315
DEG_Nend_Nbox_1 1 3 PF02207 0.598
DEG_SCF_FBW7_2 875 881 PF00400 0.511
DEG_SPOP_SBC_1 290 294 PF00917 0.442
DEG_SPOP_SBC_1 808 812 PF00917 0.508
DOC_CDC14_PxL_1 131 139 PF14671 0.442
DOC_CKS1_1 783 788 PF01111 0.417
DOC_CKS1_1 875 880 PF01111 0.452
DOC_CYCLIN_RxL_1 508 517 PF00134 0.314
DOC_CYCLIN_RxL_1 83 94 PF00134 0.447
DOC_CYCLIN_yCln2_LP_2 236 242 PF00134 0.383
DOC_CYCLIN_yCln2_LP_2 336 342 PF00134 0.300
DOC_CYCLIN_yCln2_LP_2 509 515 PF00134 0.425
DOC_CYCLIN_yCln2_LP_2 872 878 PF00134 0.462
DOC_MAPK_gen_1 205 214 PF00069 0.310
DOC_MAPK_gen_1 690 699 PF00069 0.239
DOC_MAPK_MEF2A_6 186 193 PF00069 0.370
DOC_MAPK_MEF2A_6 511 520 PF00069 0.455
DOC_MAPK_MEF2A_6 713 722 PF00069 0.288
DOC_MAPK_MEF2A_6 863 871 PF00069 0.328
DOC_MAPK_RevD_3 1134 1148 PF00069 0.554
DOC_PP1_RVXF_1 509 516 PF00149 0.315
DOC_PP1_RVXF_1 689 696 PF00149 0.243
DOC_PP1_RVXF_1 745 752 PF00149 0.327
DOC_PP2B_LxvP_1 236 239 PF13499 0.334
DOC_PP4_FxxP_1 1314 1317 PF00568 0.649
DOC_PP4_FxxP_1 165 168 PF00568 0.460
DOC_USP7_MATH_1 1019 1023 PF00917 0.623
DOC_USP7_MATH_1 1260 1264 PF00917 0.660
DOC_USP7_MATH_1 1291 1295 PF00917 0.717
DOC_USP7_MATH_1 1303 1307 PF00917 0.703
DOC_USP7_MATH_1 151 155 PF00917 0.443
DOC_USP7_MATH_1 290 294 PF00917 0.441
DOC_USP7_MATH_1 385 389 PF00917 0.357
DOC_USP7_MATH_1 456 460 PF00917 0.411
DOC_USP7_MATH_1 677 681 PF00917 0.438
DOC_USP7_MATH_1 714 718 PF00917 0.399
DOC_USP7_MATH_1 736 740 PF00917 0.434
DOC_USP7_MATH_1 779 783 PF00917 0.441
DOC_USP7_MATH_1 841 845 PF00917 0.375
DOC_USP7_MATH_1 992 996 PF00917 0.574
DOC_USP7_UBL2_3 128 132 PF12436 0.370
DOC_WW_Pin1_4 152 157 PF00397 0.399
DOC_WW_Pin1_4 244 249 PF00397 0.374
DOC_WW_Pin1_4 318 323 PF00397 0.408
DOC_WW_Pin1_4 559 564 PF00397 0.429
DOC_WW_Pin1_4 593 598 PF00397 0.394
DOC_WW_Pin1_4 765 770 PF00397 0.426
DOC_WW_Pin1_4 782 787 PF00397 0.404
DOC_WW_Pin1_4 837 842 PF00397 0.329
DOC_WW_Pin1_4 871 876 PF00397 0.427
DOC_WW_Pin1_4 880 885 PF00397 0.406
DOC_WW_Pin1_4 889 894 PF00397 0.391
LIG_14-3-3_CanoR_1 1244 1249 PF00244 0.638
LIG_14-3-3_CanoR_1 205 214 PF00244 0.351
LIG_14-3-3_CanoR_1 291 298 PF00244 0.405
LIG_14-3-3_CanoR_1 492 498 PF00244 0.316
LIG_14-3-3_CanoR_1 633 642 PF00244 0.423
LIG_14-3-3_CanoR_1 747 752 PF00244 0.455
LIG_APCC_ABBA_1 141 146 PF00400 0.439
LIG_APCC_ABBA_1 308 313 PF00400 0.305
LIG_APCC_ABBA_1 720 725 PF00400 0.311
LIG_BIR_III_2 928 932 PF00653 0.649
LIG_deltaCOP1_diTrp_1 217 222 PF00928 0.240
LIG_EH_1 1275 1279 PF12763 0.448
LIG_eIF4E_1 29 35 PF01652 0.457
LIG_eIF4E_1 599 605 PF01652 0.265
LIG_FHA_1 1006 1012 PF00498 0.570
LIG_FHA_1 1015 1021 PF00498 0.505
LIG_FHA_1 1040 1046 PF00498 0.515
LIG_FHA_1 1090 1096 PF00498 0.512
LIG_FHA_1 1244 1250 PF00498 0.629
LIG_FHA_1 305 311 PF00498 0.386
LIG_FHA_1 356 362 PF00498 0.439
LIG_FHA_1 36 42 PF00498 0.449
LIG_FHA_1 44 50 PF00498 0.479
LIG_FHA_1 548 554 PF00498 0.429
LIG_FHA_1 573 579 PF00498 0.361
LIG_FHA_1 639 645 PF00498 0.381
LIG_FHA_1 656 662 PF00498 0.344
LIG_FHA_1 679 685 PF00498 0.398
LIG_FHA_1 803 809 PF00498 0.417
LIG_FHA_1 812 818 PF00498 0.461
LIG_FHA_1 823 829 PF00498 0.404
LIG_FHA_1 840 846 PF00498 0.465
LIG_FHA_1 911 917 PF00498 0.404
LIG_FHA_1 958 964 PF00498 0.556
LIG_FHA_2 1032 1038 PF00498 0.603
LIG_FHA_2 1152 1158 PF00498 0.729
LIG_FHA_2 1162 1168 PF00498 0.717
LIG_FHA_2 183 189 PF00498 0.447
LIG_FHA_2 249 255 PF00498 0.437
LIG_FHA_2 319 325 PF00498 0.421
LIG_FHA_2 417 423 PF00498 0.421
LIG_FHA_2 486 492 PF00498 0.340
LIG_FHA_2 634 640 PF00498 0.434
LIG_FHA_2 698 704 PF00498 0.341
LIG_FHA_2 838 844 PF00498 0.432
LIG_FHA_2 941 947 PF00498 0.505
LIG_FHA_2 982 988 PF00498 0.510
LIG_GBD_Chelix_1 1002 1010 PF00786 0.413
LIG_GBD_Chelix_1 1241 1249 PF00786 0.267
LIG_GBD_Chelix_1 279 287 PF00786 0.536
LIG_GBD_Chelix_1 407 415 PF00786 0.513
LIG_LIR_Apic_2 1036 1041 PF02991 0.496
LIG_LIR_Apic_2 452 456 PF02991 0.371
LIG_LIR_Apic_2 542 546 PF02991 0.342
LIG_LIR_Apic_2 591 595 PF02991 0.374
LIG_LIR_Apic_2 596 602 PF02991 0.394
LIG_LIR_Apic_2 667 673 PF02991 0.434
LIG_LIR_Gen_1 1047 1057 PF02991 0.561
LIG_LIR_Gen_1 1069 1079 PF02991 0.604
LIG_LIR_Gen_1 209 219 PF02991 0.434
LIG_LIR_Gen_1 256 266 PF02991 0.367
LIG_LIR_Gen_1 484 495 PF02991 0.440
LIG_LIR_Gen_1 750 756 PF02991 0.371
LIG_LIR_Gen_1 939 950 PF02991 0.507
LIG_LIR_Nem_3 1021 1027 PF02991 0.509
LIG_LIR_Nem_3 1047 1053 PF02991 0.507
LIG_LIR_Nem_3 1069 1075 PF02991 0.524
LIG_LIR_Nem_3 1076 1082 PF02991 0.485
LIG_LIR_Nem_3 1105 1111 PF02991 0.520
LIG_LIR_Nem_3 1196 1201 PF02991 0.626
LIG_LIR_Nem_3 133 137 PF02991 0.384
LIG_LIR_Nem_3 209 214 PF02991 0.431
LIG_LIR_Nem_3 217 222 PF02991 0.371
LIG_LIR_Nem_3 307 311 PF02991 0.376
LIG_LIR_Nem_3 430 435 PF02991 0.437
LIG_LIR_Nem_3 484 490 PF02991 0.379
LIG_LIR_Nem_3 750 754 PF02991 0.363
LIG_LIR_Nem_3 939 945 PF02991 0.507
LIG_LIR_Nem_3 949 955 PF02991 0.609
LIG_LYPXL_yS_3 134 137 PF13949 0.309
LIG_LYPXL_yS_3 730 733 PF13949 0.428
LIG_MYND_3 615 619 PF01753 0.434
LIG_Pex14_1 218 222 PF04695 0.240
LIG_Pex14_2 165 169 PF04695 0.448
LIG_PTB_Apo_2 390 397 PF02174 0.333
LIG_PTB_Apo_2 607 614 PF02174 0.465
LIG_PTB_Apo_2 69 76 PF02174 0.371
LIG_PTB_Phospho_1 607 613 PF10480 0.467
LIG_PTB_Phospho_1 69 75 PF10480 0.379
LIG_SH2_CRK 242 246 PF00017 0.487
LIG_SH2_CRK 453 457 PF00017 0.370
LIG_SH2_CRK 626 630 PF00017 0.431
LIG_SH2_CRK 670 674 PF00017 0.465
LIG_SH2_GRB2like 391 394 PF00017 0.497
LIG_SH2_NCK_1 101 105 PF00017 0.448
LIG_SH2_NCK_1 1072 1076 PF00017 0.597
LIG_SH2_NCK_1 242 246 PF00017 0.499
LIG_SH2_PTP2 1038 1041 PF00017 0.539
LIG_SH2_PTP2 543 546 PF00017 0.236
LIG_SH2_PTP2 611 614 PF00017 0.447
LIG_SH2_SRC 1038 1041 PF00017 0.552
LIG_SH2_SRC 1072 1075 PF00017 0.597
LIG_SH2_SRC 442 445 PF00017 0.403
LIG_SH2_SRC 543 546 PF00017 0.391
LIG_SH2_STAP1 1050 1054 PF00017 0.562
LIG_SH2_STAP1 144 148 PF00017 0.215
LIG_SH2_STAP1 312 316 PF00017 0.445
LIG_SH2_STAP1 574 578 PF00017 0.377
LIG_SH2_STAT3 469 472 PF00017 0.431
LIG_SH2_STAT3 851 854 PF00017 0.342
LIG_SH2_STAT5 101 104 PF00017 0.428
LIG_SH2_STAT5 1038 1041 PF00017 0.486
LIG_SH2_STAT5 1233 1236 PF00017 0.614
LIG_SH2_STAT5 148 151 PF00017 0.362
LIG_SH2_STAT5 183 186 PF00017 0.342
LIG_SH2_STAT5 213 216 PF00017 0.300
LIG_SH2_STAT5 296 299 PF00017 0.325
LIG_SH2_STAT5 391 394 PF00017 0.447
LIG_SH2_STAT5 435 438 PF00017 0.317
LIG_SH2_STAT5 442 445 PF00017 0.302
LIG_SH2_STAT5 469 472 PF00017 0.397
LIG_SH2_STAT5 543 546 PF00017 0.379
LIG_SH2_STAT5 574 577 PF00017 0.459
LIG_SH2_STAT5 592 595 PF00017 0.478
LIG_SH2_STAT5 611 614 PF00017 0.366
LIG_SH2_STAT5 69 72 PF00017 0.409
LIG_SH3_1 1315 1321 PF00018 0.528
LIG_SH3_1 242 248 PF00018 0.262
LIG_SH3_2 245 250 PF14604 0.257
LIG_SH3_3 1216 1222 PF00018 0.596
LIG_SH3_3 1315 1321 PF00018 0.738
LIG_SH3_3 137 143 PF00018 0.327
LIG_SH3_3 242 248 PF00018 0.357
LIG_SH3_3 591 597 PF00018 0.391
LIG_SH3_3 864 870 PF00018 0.399
LIG_SH3_3 872 878 PF00018 0.413
LIG_SUMO_SIM_anti_2 121 128 PF11976 0.431
LIG_SUMO_SIM_anti_2 38 43 PF11976 0.421
LIG_SUMO_SIM_anti_2 716 725 PF11976 0.346
LIG_SUMO_SIM_anti_2 935 944 PF11976 0.508
LIG_SUMO_SIM_par_1 225 233 PF11976 0.288
LIG_SUMO_SIM_par_1 45 51 PF11976 0.444
LIG_SUMO_SIM_par_1 695 700 PF11976 0.396
LIG_SUMO_SIM_par_1 716 725 PF11976 0.401
LIG_SUMO_SIM_par_1 855 860 PF11976 0.350
LIG_SUMO_SIM_par_1 907 913 PF11976 0.442
LIG_TRAF2_1 1046 1049 PF00917 0.629
LIG_TRAF2_1 419 422 PF00917 0.466
LIG_TYR_ITIM 1070 1075 PF00017 0.484
LIG_TYR_ITIM 624 629 PF00017 0.432
LIG_TYR_ITIM 728 733 PF00017 0.380
LIG_UBA3_1 193 198 PF00899 0.578
LIG_UBA3_1 622 628 PF00899 0.478
LIG_Vh1_VBS_1 697 715 PF01044 0.200
LIG_WRC_WIRS_1 219 224 PF05994 0.329
LIG_WRC_WIRS_1 748 753 PF05994 0.585
LIG_WW_3 1221 1225 PF00397 0.614
MOD_CDC14_SPxK_1 247 250 PF00782 0.279
MOD_CDK_SPK_2 244 249 PF00069 0.291
MOD_CDK_SPK_2 880 885 PF00069 0.367
MOD_CDK_SPxK_1 244 250 PF00069 0.288
MOD_CDK_SPxxK_3 889 896 PF00069 0.459
MOD_CK1_1 1179 1185 PF00069 0.481
MOD_CK1_1 1294 1300 PF00069 0.687
MOD_CK1_1 329 335 PF00069 0.606
MOD_CK1_1 493 499 PF00069 0.464
MOD_CK1_1 504 510 PF00069 0.433
MOD_CK1_1 637 643 PF00069 0.398
MOD_CK1_1 664 670 PF00069 0.389
MOD_CK1_1 680 686 PF00069 0.489
MOD_CK1_1 758 764 PF00069 0.544
MOD_CK1_1 78 84 PF00069 0.420
MOD_CK1_1 782 788 PF00069 0.469
MOD_CK1_1 822 828 PF00069 0.361
MOD_CK1_1 874 880 PF00069 0.640
MOD_CK1_1 995 1001 PF00069 0.507
MOD_CK2_1 1043 1049 PF00069 0.529
MOD_CK2_1 1109 1115 PF00069 0.366
MOD_CK2_1 1151 1157 PF00069 0.646
MOD_CK2_1 1161 1167 PF00069 0.606
MOD_CK2_1 151 157 PF00069 0.450
MOD_CK2_1 182 188 PF00069 0.535
MOD_CK2_1 416 422 PF00069 0.437
MOD_CK2_1 456 462 PF00069 0.482
MOD_CK2_1 60 66 PF00069 0.574
MOD_CK2_1 837 843 PF00069 0.444
MOD_CK2_1 940 946 PF00069 0.355
MOD_Cter_Amidation 1145 1148 PF01082 0.495
MOD_GlcNHglycan 1021 1024 PF01048 0.505
MOD_GlcNHglycan 1144 1147 PF01048 0.487
MOD_GlcNHglycan 1170 1173 PF01048 0.595
MOD_GlcNHglycan 1262 1265 PF01048 0.482
MOD_GlcNHglycan 1271 1274 PF01048 0.416
MOD_GlcNHglycan 1293 1296 PF01048 0.690
MOD_GlcNHglycan 1301 1304 PF01048 0.669
MOD_GlcNHglycan 1305 1308 PF01048 0.637
MOD_GlcNHglycan 160 163 PF01048 0.525
MOD_GlcNHglycan 172 175 PF01048 0.362
MOD_GlcNHglycan 293 296 PF01048 0.493
MOD_GlcNHglycan 329 332 PF01048 0.617
MOD_GlcNHglycan 411 414 PF01048 0.498
MOD_GlcNHglycan 475 478 PF01048 0.506
MOD_GlcNHglycan 491 495 PF01048 0.465
MOD_GlcNHglycan 663 666 PF01048 0.485
MOD_GlcNHglycan 685 688 PF01048 0.452
MOD_GlcNHglycan 762 765 PF01048 0.437
MOD_GlcNHglycan 79 83 PF01048 0.370
MOD_GlcNHglycan 93 96 PF01048 0.443
MOD_GlcNHglycan 994 997 PF01048 0.450
MOD_GSK3_1 1039 1046 PF00069 0.511
MOD_GSK3_1 1161 1168 PF00069 0.521
MOD_GSK3_1 1175 1182 PF00069 0.582
MOD_GSK3_1 1222 1229 PF00069 0.587
MOD_GSK3_1 1299 1306 PF00069 0.695
MOD_GSK3_1 240 247 PF00069 0.488
MOD_GSK3_1 285 292 PF00069 0.490
MOD_GSK3_1 326 333 PF00069 0.603
MOD_GSK3_1 334 341 PF00069 0.512
MOD_GSK3_1 43 50 PF00069 0.484
MOD_GSK3_1 473 480 PF00069 0.550
MOD_GSK3_1 501 508 PF00069 0.477
MOD_GSK3_1 552 559 PF00069 0.490
MOD_GSK3_1 568 575 PF00069 0.459
MOD_GSK3_1 633 640 PF00069 0.396
MOD_GSK3_1 673 680 PF00069 0.471
MOD_GSK3_1 732 739 PF00069 0.507
MOD_GSK3_1 765 772 PF00069 0.446
MOD_GSK3_1 793 800 PF00069 0.535
MOD_GSK3_1 804 811 PF00069 0.519
MOD_GSK3_1 835 842 PF00069 0.515
MOD_GSK3_1 870 877 PF00069 0.537
MOD_GSK3_1 885 892 PF00069 0.527
MOD_GSK3_1 936 943 PF00069 0.372
MOD_GSK3_1 981 988 PF00069 0.364
MOD_N-GLC_1 533 538 PF02516 0.515
MOD_N-GLC_1 546 551 PF02516 0.501
MOD_N-GLC_1 556 561 PF02516 0.525
MOD_N-GLC_1 655 660 PF02516 0.459
MOD_N-GLC_2 1325 1327 PF02516 0.389
MOD_NEK2_1 1176 1181 PF00069 0.539
MOD_NEK2_1 1269 1274 PF00069 0.434
MOD_NEK2_1 169 174 PF00069 0.460
MOD_NEK2_1 182 187 PF00069 0.428
MOD_NEK2_1 261 266 PF00069 0.384
MOD_NEK2_1 35 40 PF00069 0.413
MOD_NEK2_1 47 52 PF00069 0.352
MOD_NEK2_1 661 666 PF00069 0.363
MOD_NEK2_1 697 702 PF00069 0.461
MOD_NEK2_1 797 802 PF00069 0.449
MOD_NEK2_1 910 915 PF00069 0.332
MOD_NEK2_2 296 301 PF00069 0.299
MOD_NEK2_2 769 774 PF00069 0.278
MOD_PIKK_1 400 406 PF00454 0.469
MOD_PIKK_1 495 501 PF00454 0.486
MOD_PIKK_1 779 785 PF00454 0.570
MOD_PK_1 740 746 PF00069 0.341
MOD_PK_1 819 825 PF00069 0.349
MOD_PKA_1 802 808 PF00069 0.498
MOD_PKA_2 1243 1249 PF00069 0.530
MOD_PKA_2 1291 1297 PF00069 0.693
MOD_PKA_2 206 212 PF00069 0.541
MOD_PKA_2 29 35 PF00069 0.474
MOD_PKA_2 290 296 PF00069 0.483
MOD_PKA_2 802 808 PF00069 0.305
MOD_Plk_1 361 367 PF00069 0.398
MOD_Plk_1 421 427 PF00069 0.439
MOD_Plk_1 504 510 PF00069 0.484
MOD_Plk_1 533 539 PF00069 0.500
MOD_Plk_1 638 644 PF00069 0.495
MOD_Plk_1 655 661 PF00069 0.411
MOD_Plk_1 808 814 PF00069 0.513
MOD_Plk_2-3 981 987 PF00069 0.355
MOD_Plk_4 1244 1250 PF00069 0.535
MOD_Plk_4 1280 1286 PF00069 0.585
MOD_Plk_4 133 139 PF00069 0.485
MOD_Plk_4 144 150 PF00069 0.442
MOD_Plk_4 35 41 PF00069 0.326
MOD_Plk_4 361 367 PF00069 0.501
MOD_Plk_4 411 417 PF00069 0.547
MOD_Plk_4 421 427 PF00069 0.452
MOD_Plk_4 514 520 PF00069 0.447
MOD_Plk_4 627 633 PF00069 0.401
MOD_Plk_4 714 720 PF00069 0.467
MOD_Plk_4 729 735 PF00069 0.453
MOD_Plk_4 769 775 PF00069 0.522
MOD_Plk_4 912 918 PF00069 0.357
MOD_Plk_4 936 942 PF00069 0.353
MOD_Plk_4 985 991 PF00069 0.369
MOD_ProDKin_1 152 158 PF00069 0.480
MOD_ProDKin_1 244 250 PF00069 0.446
MOD_ProDKin_1 318 324 PF00069 0.500
MOD_ProDKin_1 559 565 PF00069 0.526
MOD_ProDKin_1 593 599 PF00069 0.477
MOD_ProDKin_1 765 771 PF00069 0.523
MOD_ProDKin_1 782 788 PF00069 0.492
MOD_ProDKin_1 837 843 PF00069 0.389
MOD_ProDKin_1 871 877 PF00069 0.522
MOD_ProDKin_1 880 886 PF00069 0.495
MOD_ProDKin_1 889 895 PF00069 0.468
MOD_SUMO_rev_2 113 118 PF00179 0.344
MOD_SUMO_rev_2 364 373 PF00179 0.563
TRG_DiLeu_BaEn_1 66 71 PF01217 0.522
TRG_DiLeu_BaEn_1 936 941 PF01217 0.485
TRG_DiLeu_BaEn_2 618 624 PF01217 0.355
TRG_DiLeu_BaEn_4 1048 1054 PF01217 0.389
TRG_DiLeu_BaLyEn_6 30 35 PF01217 0.438
TRG_DiLeu_BaLyEn_6 766 771 PF01217 0.310
TRG_DiLeu_LyEn_5 1209 1214 PF01217 0.526
TRG_DiLeu_LyEn_5 521 526 PF01217 0.213
TRG_ENDOCYTIC_2 1024 1027 PF00928 0.362
TRG_ENDOCYTIC_2 1050 1053 PF00928 0.345
TRG_ENDOCYTIC_2 1072 1075 PF00928 0.482
TRG_ENDOCYTIC_2 134 137 PF00928 0.520
TRG_ENDOCYTIC_2 311 314 PF00928 0.502
TRG_ENDOCYTIC_2 611 614 PF00928 0.556
TRG_ENDOCYTIC_2 626 629 PF00928 0.472
TRG_ENDOCYTIC_2 730 733 PF00928 0.383
TRG_ER_diArg_1 1057 1060 PF00400 0.356
TRG_ER_diArg_1 204 207 PF00400 0.482
TRG_ER_diArg_1 689 692 PF00400 0.550
TRG_ER_diArg_1 8 10 PF00400 0.341
TRG_ER_diArg_1 801 803 PF00400 0.556
TRG_NES_CRM1_1 225 237 PF08389 0.409
TRG_NES_CRM1_1 577 591 PF08389 0.259
TRG_NES_CRM1_1 709 725 PF08389 0.199
TRG_Pf-PMV_PEXEL_1 802 806 PF00026 0.364
TRG_Pf-PMV_PEXEL_1 968 972 PF00026 0.430

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P457 Leptomonas seymouri 29% 100%
A0A1X0NPQ6 Trypanosomatidae 28% 100%
A0A1X0P171 Trypanosomatidae 32% 100%
A0A3Q8IJB0 Leishmania donovani 82% 100%
A0A3R7R8G4 Trypanosoma rangeli 31% 100%
A0A3S5H6Z8 Leishmania donovani 82% 100%
A0A3S7WU91 Leishmania donovani 63% 94%
A0A3S7WU94 Leishmania donovani 55% 97%
A0A3S7WU95 Leishmania donovani 79% 95%
A0A3S7XB85 Leishmania donovani 28% 94%
A4H8U6 Leishmania braziliensis 54% 100%
A4H8V5 Leishmania braziliensis 62% 100%
A4H8V7 Leishmania braziliensis 67% 100%
A4H8V8 Leishmania braziliensis 70% 100%
A4HPI4 Leishmania braziliensis 26% 100%
A4HX84 Leishmania infantum 55% 97%
A4HX85 Leishmania infantum 83% 95%
A4HX87 Leishmania infantum 63% 100%
A4HX88 Leishmania infantum 77% 100%
A4IDA6 Leishmania infantum 29% 95%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 29% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 98%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
E9AQY0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 65% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 61% 96%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 58% 97%
E9AT96 Leishmania mexicana (strain MHOM/GT/2001/U1103) 29% 94%
Q25263 Leishmania donovani 82% 100%
Q26721 Trypanosoma brucei brucei 33% 100%
Q27675 Leishmania donovani 55% 96%
Q4Q1A1 Leishmania major 27% 100%
Q4QEH9 Leishmania major 83% 100%
Q4QEI0 Leishmania major 83% 100%
Q4QEI1 Leishmania major 83% 100%
Q4QEI2 Leishmania major 61% 100%
Q4QEI3 Leishmania major 55% 100%
Q99279 Trypanosoma brucei brucei 29% 100%
Q99280 Trypanosoma brucei brucei 33% 100%
V5AYH7 Trypanosoma cruzi 33% 100%
V5B1C8 Trypanosoma cruzi 38% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS