LeishMANIAdb
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ATP pyrophosphate-lyase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
ATP pyrophosphate-lyase
Gene product:
receptor-type adenylate cyclase, putative
Species:
Leishmania mexicana
UniProt:
E9AQY0_LEIMU
TriTrypDb:
LmxM.17.0190 *
Length:
1411

Annotations

LeishMANIAdb annotations

Carries an ATP pyrophosphate-lyase domain on its cytoplasmic segment. Likely acts as a receptor for some unknown extracellular stimulus. Extremely expanded kinetoplastid protein family.. Expressed in the insect stage (promastigote) but not in the mammalian host stage of the parasite life cycle.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 51
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 42, no: 26
NetGPI no yes: 0, no: 68
Cellular components
Term Name Level Count
GO:0016020 membrane 2 65
GO:0110165 cellular anatomical entity 1 69

Expansion

Sequence features

E9AQY0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 69
GO:0006163 purine nucleotide metabolic process 5 69
GO:0006164 purine nucleotide biosynthetic process 6 69
GO:0006171 cAMP biosynthetic process 8 69
GO:0006725 cellular aromatic compound metabolic process 3 69
GO:0006753 nucleoside phosphate metabolic process 4 69
GO:0006793 phosphorus metabolic process 3 69
GO:0006796 phosphate-containing compound metabolic process 4 69
GO:0006807 nitrogen compound metabolic process 2 69
GO:0007165 signal transduction 2 69
GO:0008152 metabolic process 1 69
GO:0009058 biosynthetic process 2 69
GO:0009117 nucleotide metabolic process 5 69
GO:0009150 purine ribonucleotide metabolic process 6 69
GO:0009152 purine ribonucleotide biosynthetic process 7 69
GO:0009165 nucleotide biosynthetic process 6 69
GO:0009187 cyclic nucleotide metabolic process 6 69
GO:0009190 cyclic nucleotide biosynthetic process 7 69
GO:0009259 ribonucleotide metabolic process 5 69
GO:0009260 ribonucleotide biosynthetic process 6 69
GO:0009987 cellular process 1 69
GO:0018130 heterocycle biosynthetic process 4 69
GO:0019438 aromatic compound biosynthetic process 4 69
GO:0019637 organophosphate metabolic process 3 69
GO:0019693 ribose phosphate metabolic process 4 69
GO:0034641 cellular nitrogen compound metabolic process 3 69
GO:0034654 nucleobase-containing compound biosynthetic process 4 69
GO:0035556 intracellular signal transduction 3 69
GO:0044237 cellular metabolic process 2 69
GO:0044238 primary metabolic process 2 69
GO:0044249 cellular biosynthetic process 3 69
GO:0044271 cellular nitrogen compound biosynthetic process 4 69
GO:0044281 small molecule metabolic process 2 69
GO:0046058 cAMP metabolic process 7 69
GO:0046390 ribose phosphate biosynthetic process 5 69
GO:0046483 heterocycle metabolic process 3 69
GO:0050789 regulation of biological process 2 69
GO:0050794 regulation of cellular process 3 69
GO:0052652 cyclic purine nucleotide metabolic process 6 69
GO:0055086 nucleobase-containing small molecule metabolic process 3 69
GO:0065007 biological regulation 1 69
GO:0071704 organic substance metabolic process 2 69
GO:0072521 purine-containing compound metabolic process 4 69
GO:0072522 purine-containing compound biosynthetic process 5 69
GO:0090407 organophosphate biosynthetic process 4 69
GO:1901135 carbohydrate derivative metabolic process 3 69
GO:1901137 carbohydrate derivative biosynthetic process 4 69
GO:1901293 nucleoside phosphate biosynthetic process 5 69
GO:1901360 organic cyclic compound metabolic process 3 69
GO:1901362 organic cyclic compound biosynthetic process 4 69
GO:1901564 organonitrogen compound metabolic process 3 69
GO:1901566 organonitrogen compound biosynthetic process 4 69
GO:1901576 organic substance biosynthetic process 3 69
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 60
GO:0016829 lyase activity 2 60

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 395 399 PF00656 0.503
CLV_C14_Caspase3-7 769 773 PF00656 0.406
CLV_C14_Caspase3-7 91 95 PF00656 0.425
CLV_C14_Caspase3-7 933 937 PF00656 0.605
CLV_C14_Caspase3-7 994 998 PF00656 0.504
CLV_MEL_PAP_1 1067 1073 PF00089 0.307
CLV_NRD_NRD_1 1157 1159 PF00675 0.461
CLV_NRD_NRD_1 1325 1327 PF00675 0.523
CLV_NRD_NRD_1 1365 1367 PF00675 0.601
CLV_NRD_NRD_1 1395 1397 PF00675 0.551
CLV_NRD_NRD_1 217 219 PF00675 0.608
CLV_NRD_NRD_1 26 28 PF00675 0.345
CLV_NRD_NRD_1 41 43 PF00675 0.358
CLV_NRD_NRD_1 437 439 PF00675 0.488
CLV_NRD_NRD_1 535 537 PF00675 0.577
CLV_NRD_NRD_1 670 672 PF00675 0.540
CLV_PCSK_FUR_1 215 219 PF00082 0.610
CLV_PCSK_FUR_1 27 31 PF00082 0.241
CLV_PCSK_KEX2_1 1157 1159 PF00082 0.461
CLV_PCSK_KEX2_1 1325 1327 PF00082 0.519
CLV_PCSK_KEX2_1 1365 1367 PF00082 0.608
CLV_PCSK_KEX2_1 1394 1396 PF00082 0.547
CLV_PCSK_KEX2_1 217 219 PF00082 0.610
CLV_PCSK_KEX2_1 26 28 PF00082 0.362
CLV_PCSK_KEX2_1 29 31 PF00082 0.383
CLV_PCSK_KEX2_1 41 43 PF00082 0.353
CLV_PCSK_PC1ET2_1 29 31 PF00082 0.457
CLV_PCSK_SKI1_1 117 121 PF00082 0.725
CLV_PCSK_SKI1_1 218 222 PF00082 0.602
CLV_PCSK_SKI1_1 265 269 PF00082 0.544
CLV_PCSK_SKI1_1 29 33 PF00082 0.352
CLV_PCSK_SKI1_1 315 319 PF00082 0.470
CLV_PCSK_SKI1_1 515 519 PF00082 0.590
CLV_PCSK_SKI1_1 664 668 PF00082 0.535
CLV_PCSK_SKI1_1 799 803 PF00082 0.573
CLV_PCSK_SKI1_1 93 97 PF00082 0.669
DEG_APCC_DBOX_1 1325 1333 PF00400 0.720
DEG_APCC_DBOX_1 40 48 PF00400 0.606
DEG_APCC_DBOX_1 721 729 PF00400 0.274
DEG_APCC_DBOX_1 798 806 PF00400 0.324
DEG_APCC_DBOX_1 894 902 PF00400 0.360
DEG_APCC_KENBOX_2 616 620 PF00400 0.237
DEG_MDM2_SWIB_1 492 499 PF02201 0.217
DEG_ODPH_VHL_1 697 708 PF01847 0.240
DEG_SCF_FBW7_2 885 891 PF00400 0.527
DEG_SPOP_SBC_1 300 304 PF00917 0.438
DOC_CDC14_PxL_1 529 537 PF14671 0.243
DOC_CDC14_PxL_1 774 782 PF14671 0.240
DOC_CKS1_1 885 890 PF01111 0.471
DOC_CYCLIN_RxL_1 1032 1043 PF00134 0.391
DOC_CYCLIN_yCln2_LP_2 246 252 PF00134 0.404
DOC_CYCLIN_yCln2_LP_2 518 524 PF00134 0.397
DOC_MAPK_FxFP_2 504 507 PF00069 0.254
DOC_MAPK_gen_1 1341 1347 PF00069 0.743
DOC_MAPK_gen_1 169 176 PF00069 0.233
DOC_MAPK_gen_1 215 224 PF00069 0.316
DOC_MAPK_gen_1 26 37 PF00069 0.673
DOC_MAPK_gen_1 41 51 PF00069 0.604
DOC_MAPK_gen_1 616 623 PF00069 0.264
DOC_MAPK_gen_1 93 102 PF00069 0.463
DOC_MAPK_MEF2A_6 42 51 PF00069 0.512
DOC_MAPK_MEF2A_6 520 529 PF00069 0.433
DOC_MAPK_MEF2A_6 722 729 PF00069 0.292
DOC_MAPK_MEF2A_6 799 806 PF00069 0.342
DOC_MAPK_MEF2A_6 906 915 PF00069 0.250
DOC_MAPK_MEF2A_6 93 102 PF00069 0.460
DOC_MAPK_RevD_3 1144 1158 PF00069 0.592
DOC_MAPK_RevD_3 203 218 PF00069 0.282
DOC_MAPK_RevD_3 601 617 PF00069 0.208
DOC_PP1_RVXF_1 169 176 PF00149 0.345
DOC_PP1_RVXF_1 313 319 PF00149 0.430
DOC_PP1_RVXF_1 552 558 PF00149 0.334
DOC_PP2B_LxvP_1 246 249 PF13499 0.346
DOC_PP2B_PxIxI_1 610 616 PF00149 0.201
DOC_PP4_FxxP_1 175 178 PF00568 0.459
DOC_PP4_FxxP_1 504 507 PF00568 0.254
DOC_PP4_FxxP_1 608 611 PF00568 0.261
DOC_PP4_FxxP_1 622 625 PF00568 0.349
DOC_PP4_FxxP_1 677 680 PF00568 0.451
DOC_PP4_FxxP_1 787 790 PF00568 0.461
DOC_PP4_FxxP_1 817 820 PF00568 0.275
DOC_USP7_MATH_1 1002 1006 PF00917 0.582
DOC_USP7_MATH_1 1029 1033 PF00917 0.614
DOC_USP7_MATH_1 126 130 PF00917 0.356
DOC_USP7_MATH_1 1270 1274 PF00917 0.679
DOC_USP7_MATH_1 1301 1305 PF00917 0.734
DOC_USP7_MATH_1 1313 1317 PF00917 0.752
DOC_USP7_MATH_1 1361 1365 PF00917 0.635
DOC_USP7_MATH_1 1376 1380 PF00917 0.561
DOC_USP7_MATH_1 240 244 PF00917 0.281
DOC_USP7_MATH_1 300 304 PF00917 0.436
DOC_USP7_MATH_1 394 398 PF00917 0.398
DOC_USP7_MATH_1 643 647 PF00917 0.390
DOC_USP7_MATH_1 686 690 PF00917 0.451
DOC_USP7_MATH_1 880 884 PF00917 0.440
DOC_USP7_UBL2_3 380 384 PF12436 0.483
DOC_WW_Pin1_4 328 333 PF00397 0.415
DOC_WW_Pin1_4 602 607 PF00397 0.337
DOC_WW_Pin1_4 767 772 PF00397 0.452
DOC_WW_Pin1_4 791 796 PF00397 0.363
DOC_WW_Pin1_4 881 886 PF00397 0.456
DOC_WW_Pin1_4 899 904 PF00397 0.464
LIG_14-3-3_CanoR_1 1236 1243 PF00244 0.672
LIG_14-3-3_CanoR_1 1254 1259 PF00244 0.709
LIG_14-3-3_CanoR_1 1325 1330 PF00244 0.694
LIG_14-3-3_CanoR_1 1336 1345 PF00244 0.672
LIG_14-3-3_CanoR_1 1374 1379 PF00244 0.554
LIG_14-3-3_CanoR_1 215 224 PF00244 0.354
LIG_14-3-3_CanoR_1 301 308 PF00244 0.403
LIG_14-3-3_CanoR_1 36 44 PF00244 0.505
LIG_14-3-3_CanoR_1 438 442 PF00244 0.340
LIG_14-3-3_CanoR_1 484 488 PF00244 0.240
LIG_14-3-3_CanoR_1 671 679 PF00244 0.386
LIG_14-3-3_CanoR_1 694 698 PF00244 0.405
LIG_14-3-3_CanoR_1 756 761 PF00244 0.448
LIG_14-3-3_CanoR_1 842 846 PF00244 0.461
LIG_Actin_WH2_2 1009 1024 PF00022 0.400
LIG_Actin_WH2_2 199 214 PF00022 0.265
LIG_Actin_WH2_2 221 237 PF00022 0.224
LIG_Actin_WH2_2 520 538 PF00022 0.321
LIG_Actin_WH2_2 578 596 PF00022 0.237
LIG_AP2alpha_2 198 200 PF02296 0.246
LIG_APCC_ABBA_1 151 156 PF00400 0.449
LIG_APCC_ABBA_1 318 323 PF00400 0.319
LIG_APCC_ABBA_1 354 359 PF00400 0.236
LIG_BIR_II_1 1 5 PF00653 0.561
LIG_BIR_III_2 938 942 PF00653 0.715
LIG_BRCT_BRCA1_1 164 168 PF00533 0.428
LIG_BRCT_BRCA1_1 604 608 PF00533 0.237
LIG_BRCT_BRCA1_1 746 750 PF00533 0.223
LIG_BRCT_BRCA1_1 802 806 PF00533 0.414
LIG_DLG_GKlike_1 756 763 PF00625 0.285
LIG_EH_1 1285 1289 PF12763 0.462
LIG_EH1_1 310 318 PF00400 0.195
LIG_eIF4E_1 223 229 PF01652 0.203
LIG_eIF4E_1 777 783 PF01652 0.248
LIG_FHA_1 1016 1022 PF00498 0.579
LIG_FHA_1 1025 1031 PF00498 0.520
LIG_FHA_1 1050 1056 PF00498 0.525
LIG_FHA_1 1100 1106 PF00498 0.510
LIG_FHA_1 206 212 PF00498 0.318
LIG_FHA_1 223 229 PF00498 0.236
LIG_FHA_1 349 355 PF00498 0.348
LIG_FHA_1 409 415 PF00498 0.365
LIG_FHA_1 587 593 PF00498 0.321
LIG_FHA_1 674 680 PF00498 0.364
LIG_FHA_1 73 79 PF00498 0.276
LIG_FHA_1 792 798 PF00498 0.397
LIG_FHA_1 8 14 PF00498 0.424
LIG_FHA_1 82 88 PF00498 0.298
LIG_FHA_1 849 855 PF00498 0.446
LIG_FHA_1 968 974 PF00498 0.562
LIG_FHA_2 1042 1048 PF00498 0.604
LIG_FHA_2 1162 1168 PF00498 0.736
LIG_FHA_2 1172 1178 PF00498 0.720
LIG_FHA_2 193 199 PF00498 0.461
LIG_FHA_2 329 335 PF00498 0.432
LIG_FHA_2 347 353 PF00498 0.362
LIG_FHA_2 569 575 PF00498 0.251
LIG_FHA_2 657 663 PF00498 0.360
LIG_FHA_2 707 713 PF00498 0.352
LIG_FHA_2 767 773 PF00498 0.283
LIG_FHA_2 850 856 PF00498 0.430
LIG_FHA_2 89 95 PF00498 0.437
LIG_FHA_2 951 957 PF00498 0.504
LIG_FHA_2 992 998 PF00498 0.509
LIG_GBD_Chelix_1 1012 1020 PF00786 0.413
LIG_GBD_Chelix_1 289 297 PF00786 0.546
LIG_GBD_Chelix_1 416 424 PF00786 0.530
LIG_GBD_Chelix_1 425 433 PF00786 0.473
LIG_Integrin_isoDGR_2 115 117 PF01839 0.484
LIG_Integrin_RGD_1 196 198 PF01839 0.456
LIG_IRF3_LxIS_1 598 605 PF10401 0.236
LIG_LIR_Apic_2 1046 1051 PF02991 0.505
LIG_LIR_Apic_2 172 178 PF02991 0.452
LIG_LIR_Apic_2 461 465 PF02991 0.397
LIG_LIR_Apic_2 605 611 PF02991 0.335
LIG_LIR_Apic_2 676 680 PF02991 0.455
LIG_LIR_Apic_2 814 820 PF02991 0.365
LIG_LIR_Gen_1 1057 1067 PF02991 0.567
LIG_LIR_Gen_1 1079 1089 PF02991 0.600
LIG_LIR_Gen_1 198 207 PF02991 0.429
LIG_LIR_Gen_1 219 229 PF02991 0.426
LIG_LIR_Gen_1 526 535 PF02991 0.339
LIG_LIR_Gen_1 556 565 PF02991 0.369
LIG_LIR_Gen_1 577 585 PF02991 0.362
LIG_LIR_Gen_1 618 627 PF02991 0.435
LIG_LIR_Gen_1 731 739 PF02991 0.275
LIG_LIR_Gen_1 747 758 PF02991 0.299
LIG_LIR_Gen_1 759 765 PF02991 0.418
LIG_LIR_Gen_1 917 928 PF02991 0.278
LIG_LIR_Gen_1 949 960 PF02991 0.506
LIG_LIR_Nem_3 1031 1037 PF02991 0.506
LIG_LIR_Nem_3 1057 1063 PF02991 0.512
LIG_LIR_Nem_3 1079 1085 PF02991 0.526
LIG_LIR_Nem_3 1086 1092 PF02991 0.483
LIG_LIR_Nem_3 1115 1121 PF02991 0.524
LIG_LIR_Nem_3 1206 1211 PF02991 0.639
LIG_LIR_Nem_3 198 203 PF02991 0.313
LIG_LIR_Nem_3 219 224 PF02991 0.422
LIG_LIR_Nem_3 273 278 PF02991 0.237
LIG_LIR_Nem_3 526 532 PF02991 0.362
LIG_LIR_Nem_3 556 560 PF02991 0.375
LIG_LIR_Nem_3 577 583 PF02991 0.288
LIG_LIR_Nem_3 618 623 PF02991 0.419
LIG_LIR_Nem_3 630 635 PF02991 0.353
LIG_LIR_Nem_3 731 735 PF02991 0.288
LIG_LIR_Nem_3 736 742 PF02991 0.317
LIG_LIR_Nem_3 747 753 PF02991 0.311
LIG_LIR_Nem_3 759 763 PF02991 0.419
LIG_LIR_Nem_3 775 780 PF02991 0.330
LIG_LIR_Nem_3 855 861 PF02991 0.451
LIG_LIR_Nem_3 917 923 PF02991 0.278
LIG_LIR_Nem_3 949 955 PF02991 0.506
LIG_LIR_Nem_3 959 965 PF02991 0.615
LIG_LYPXL_yS_3 275 278 PF13949 0.224
LIG_LYPXL_yS_3 777 780 PF13949 0.246
LIG_MYND_3 624 628 PF01753 0.399
LIG_NRBOX 597 603 PF00104 0.232
LIG_NRBOX 797 803 PF00104 0.244
LIG_PCNA_TLS_4 358 366 PF02747 0.215
LIG_PCNA_yPIPBox_3 406 420 PF02747 0.251
LIG_PCNA_yPIPBox_3 900 914 PF02747 0.316
LIG_PDZ_Class_3 1406 1411 PF00595 0.602
LIG_Pex14_2 175 179 PF04695 0.451
LIG_Pex14_2 492 496 PF04695 0.221
LIG_Pex14_2 746 750 PF04695 0.236
LIG_Pex14_2 783 787 PF04695 0.301
LIG_PTB_Apo_2 399 406 PF02174 0.370
LIG_PTB_Apo_2 73 80 PF02174 0.422
LIG_PTB_Apo_2 781 788 PF02174 0.251
LIG_PTB_Phospho_1 399 405 PF10480 0.282
LIG_PTB_Phospho_1 73 79 PF10480 0.427
LIG_SH2_CRK 252 256 PF00017 0.485
LIG_SH2_CRK 462 466 PF00017 0.396
LIG_SH2_GRB2like 400 403 PF00017 0.385
LIG_SH2_GRB2like 580 583 PF00017 0.206
LIG_SH2_NCK_1 1082 1086 PF00017 0.600
LIG_SH2_NCK_1 252 256 PF00017 0.486
LIG_SH2_NCK_1 658 662 PF00017 0.451
LIG_SH2_PTP2 1048 1051 PF00017 0.551
LIG_SH2_SRC 1048 1051 PF00017 0.562
LIG_SH2_SRC 1082 1085 PF00017 0.600
LIG_SH2_SRC 369 372 PF00017 0.345
LIG_SH2_SRC 451 454 PF00017 0.409
LIG_SH2_STAP1 1060 1064 PF00017 0.567
LIG_SH2_STAP1 322 326 PF00017 0.434
LIG_SH2_STAP1 583 587 PF00017 0.379
LIG_SH2_STAP1 836 840 PF00017 0.394
LIG_SH2_STAT3 478 481 PF00017 0.432
LIG_SH2_STAT3 861 864 PF00017 0.342
LIG_SH2_STAT5 1048 1051 PF00017 0.496
LIG_SH2_STAT5 107 110 PF00017 0.431
LIG_SH2_STAT5 111 114 PF00017 0.461
LIG_SH2_STAT5 1243 1246 PF00017 0.617
LIG_SH2_STAT5 193 196 PF00017 0.364
LIG_SH2_STAT5 223 226 PF00017 0.303
LIG_SH2_STAT5 306 309 PF00017 0.318
LIG_SH2_STAT5 364 367 PF00017 0.261
LIG_SH2_STAT5 369 372 PF00017 0.270
LIG_SH2_STAT5 400 403 PF00017 0.481
LIG_SH2_STAT5 451 454 PF00017 0.306
LIG_SH2_STAT5 478 481 PF00017 0.401
LIG_SH2_STAT5 512 515 PF00017 0.318
LIG_SH2_STAT5 580 583 PF00017 0.426
LIG_SH2_STAT5 620 623 PF00017 0.345
LIG_SH2_STAT5 632 635 PF00017 0.282
LIG_SH2_STAT5 658 661 PF00017 0.381
LIG_SH2_STAT5 79 82 PF00017 0.464
LIG_SH2_STAT5 929 932 PF00017 0.559
LIG_SH3_3 1226 1232 PF00018 0.617
LIG_SH3_3 1382 1388 PF00018 0.555
LIG_SH3_3 147 153 PF00018 0.355
LIG_SH3_3 494 500 PF00018 0.363
LIG_SH3_3 585 591 PF00018 0.393
LIG_SH3_3 600 606 PF00018 0.351
LIG_SH3_3 676 682 PF00018 0.390
LIG_SH3_3 874 880 PF00018 0.414
LIG_SH3_3 882 888 PF00018 0.438
LIG_SH3_3 919 925 PF00018 0.475
LIG_SUMO_SIM_anti_2 131 138 PF11976 0.461
LIG_SUMO_SIM_anti_2 1381 1386 PF11976 0.590
LIG_SUMO_SIM_anti_2 201 208 PF11976 0.232
LIG_SUMO_SIM_anti_2 584 589 PF11976 0.293
LIG_SUMO_SIM_anti_2 599 605 PF11976 0.316
LIG_SUMO_SIM_anti_2 709 718 PF11976 0.328
LIG_SUMO_SIM_anti_2 800 806 PF11976 0.280
LIG_SUMO_SIM_anti_2 865 870 PF11976 0.424
LIG_SUMO_SIM_anti_2 945 954 PF11976 0.506
LIG_SUMO_SIM_par_1 546 551 PF11976 0.350
LIG_SUMO_SIM_par_1 599 605 PF11976 0.283
LIG_SUMO_SIM_par_1 726 731 PF11976 0.399
LIG_SUMO_SIM_par_1 865 870 PF11976 0.349
LIG_SUMO_SIM_par_1 912 917 PF11976 0.469
LIG_TRAF2_1 1056 1059 PF00917 0.627
LIG_TRAF2_1 1367 1370 PF00917 0.604
LIG_TRFH_1 244 248 PF08558 0.243
LIG_TRFH_1 85 89 PF08558 0.295
LIG_TYR_ITIM 1080 1085 PF00017 0.486
LIG_TYR_ITIM 633 638 PF00017 0.478
LIG_UBA3_1 206 213 PF00899 0.401
LIG_WRC_WIRS_1 241 246 PF05994 0.300
LIG_WRC_WIRS_1 716 721 PF05994 0.477
LIG_WRC_WIRS_1 729 734 PF05994 0.343
LIG_WRC_WIRS_1 757 762 PF05994 0.497
LIG_WW_3 1231 1235 PF00397 0.682
MOD_CDK_SPxxK_3 899 906 PF00069 0.493
MOD_CK1_1 1005 1011 PF00069 0.508
MOD_CK1_1 1189 1195 PF00069 0.526
MOD_CK1_1 1304 1310 PF00069 0.690
MOD_CK1_1 1335 1341 PF00069 0.645
MOD_CK1_1 1346 1352 PF00069 0.631
MOD_CK1_1 239 245 PF00069 0.478
MOD_CK1_1 339 345 PF00069 0.625
MOD_CK1_1 432 438 PF00069 0.334
MOD_CK1_1 688 694 PF00069 0.489
MOD_CK1_1 718 724 PF00069 0.456
MOD_CK1_1 767 773 PF00069 0.505
MOD_CK1_1 883 889 PF00069 0.653
MOD_CK2_1 1053 1059 PF00069 0.527
MOD_CK2_1 1119 1125 PF00069 0.363
MOD_CK2_1 1161 1167 PF00069 0.665
MOD_CK2_1 1171 1177 PF00069 0.614
MOD_CK2_1 1395 1401 PF00069 0.707
MOD_CK2_1 346 352 PF00069 0.508
MOD_CK2_1 483 489 PF00069 0.212
MOD_CK2_1 643 649 PF00069 0.403
MOD_CK2_1 819 825 PF00069 0.529
MOD_CK2_1 849 855 PF00069 0.433
MOD_CK2_1 950 956 PF00069 0.354
MOD_Cter_Amidation 1155 1158 PF01082 0.566
MOD_GlcNHglycan 1004 1007 PF01048 0.458
MOD_GlcNHglycan 103 106 PF01048 0.474
MOD_GlcNHglycan 1031 1034 PF01048 0.500
MOD_GlcNHglycan 1180 1183 PF01048 0.604
MOD_GlcNHglycan 1272 1275 PF01048 0.547
MOD_GlcNHglycan 1281 1284 PF01048 0.470
MOD_GlcNHglycan 1303 1306 PF01048 0.678
MOD_GlcNHglycan 1311 1314 PF01048 0.510
MOD_GlcNHglycan 1315 1318 PF01048 0.703
MOD_GlcNHglycan 1374 1377 PF01048 0.709
MOD_GlcNHglycan 238 241 PF01048 0.457
MOD_GlcNHglycan 303 306 PF01048 0.487
MOD_GlcNHglycan 339 342 PF01048 0.632
MOD_GlcNHglycan 37 40 PF01048 0.430
MOD_GlcNHglycan 420 423 PF01048 0.492
MOD_GlcNHglycan 508 511 PF01048 0.403
MOD_GlcNHglycan 556 560 PF01048 0.421
MOD_GlcNHglycan 597 601 PF01048 0.440
MOD_GlcNHglycan 659 662 PF01048 0.459
MOD_GlcNHglycan 688 691 PF01048 0.414
MOD_GlcNHglycan 825 828 PF01048 0.528
MOD_GSK3_1 1049 1056 PF00069 0.517
MOD_GSK3_1 106 113 PF00069 0.394
MOD_GSK3_1 1171 1178 PF00069 0.539
MOD_GSK3_1 1185 1192 PF00069 0.317
MOD_GSK3_1 1232 1239 PF00069 0.627
MOD_GSK3_1 1309 1316 PF00069 0.707
MOD_GSK3_1 1332 1339 PF00069 0.654
MOD_GSK3_1 1357 1364 PF00069 0.730
MOD_GSK3_1 1370 1377 PF00069 0.717
MOD_GSK3_1 158 165 PF00069 0.401
MOD_GSK3_1 17 24 PF00069 0.396
MOD_GSK3_1 2 9 PF00069 0.484
MOD_GSK3_1 201 208 PF00069 0.556
MOD_GSK3_1 236 243 PF00069 0.458
MOD_GSK3_1 250 257 PF00069 0.474
MOD_GSK3_1 295 302 PF00069 0.480
MOD_GSK3_1 336 343 PF00069 0.607
MOD_GSK3_1 425 432 PF00069 0.331
MOD_GSK3_1 523 530 PF00069 0.409
MOD_GSK3_1 592 599 PF00069 0.373
MOD_GSK3_1 643 650 PF00069 0.406
MOD_GSK3_1 685 692 PF00069 0.487
MOD_GSK3_1 740 747 PF00069 0.520
MOD_GSK3_1 766 773 PF00069 0.411
MOD_GSK3_1 819 826 PF00069 0.512
MOD_GSK3_1 83 90 PF00069 0.419
MOD_GSK3_1 841 848 PF00069 0.519
MOD_GSK3_1 880 887 PF00069 0.576
MOD_GSK3_1 946 953 PF00069 0.368
MOD_GSK3_1 991 998 PF00069 0.364
MOD_N-GLC_1 109 114 PF02516 0.282
MOD_N-GLC_1 527 532 PF02516 0.480
MOD_N-GLC_1 565 570 PF02516 0.423
MOD_N-GLC_1 581 586 PF02516 0.472
MOD_N-GLC_1 791 796 PF02516 0.456
MOD_N-GLC_1 81 86 PF02516 0.433
MOD_N-GLC_1 845 850 PF02516 0.476
MOD_NEK2_1 106 111 PF00069 0.370
MOD_NEK2_1 1186 1191 PF00069 0.571
MOD_NEK2_1 1279 1284 PF00069 0.580
MOD_NEK2_1 1318 1323 PF00069 0.725
MOD_NEK2_1 1332 1337 PF00069 0.462
MOD_NEK2_1 157 162 PF00069 0.454
MOD_NEK2_1 179 184 PF00069 0.478
MOD_NEK2_1 222 227 PF00069 0.445
MOD_NEK2_1 236 241 PF00069 0.459
MOD_NEK2_1 271 276 PF00069 0.386
MOD_NEK2_1 35 40 PF00069 0.514
MOD_NEK2_1 420 425 PF00069 0.388
MOD_NEK2_1 429 434 PF00069 0.316
MOD_NEK2_1 446 451 PF00069 0.261
MOD_NEK2_1 548 553 PF00069 0.423
MOD_NEK2_1 555 560 PF00069 0.405
MOD_NEK2_1 758 763 PF00069 0.323
MOD_NEK2_1 81 86 PF00069 0.387
MOD_NEK2_1 823 828 PF00069 0.389
MOD_NEK2_2 306 311 PF00069 0.301
MOD_NEK2_2 7 12 PF00069 0.209
MOD_PIKK_1 1256 1262 PF00454 0.673
MOD_PIKK_1 901 907 PF00454 0.300
MOD_PK_1 1374 1380 PF00069 0.458
MOD_PKA_1 1325 1331 PF00069 0.661
MOD_PKA_1 1341 1347 PF00069 0.704
MOD_PKA_1 1365 1371 PF00069 0.558
MOD_PKA_1 1395 1401 PF00069 0.464
MOD_PKA_2 11 17 PF00069 0.480
MOD_PKA_2 1253 1259 PF00069 0.552
MOD_PKA_2 1301 1307 PF00069 0.691
MOD_PKA_2 1318 1324 PF00069 0.706
MOD_PKA_2 1325 1331 PF00069 0.678
MOD_PKA_2 1335 1341 PF00069 0.665
MOD_PKA_2 1365 1371 PF00069 0.765
MOD_PKA_2 1395 1401 PF00069 0.501
MOD_PKA_2 216 222 PF00069 0.533
MOD_PKA_2 300 306 PF00069 0.488
MOD_PKA_2 35 41 PF00069 0.480
MOD_PKA_2 437 443 PF00069 0.381
MOD_PKA_2 483 489 PF00069 0.252
MOD_PKA_2 568 574 PF00069 0.446
MOD_PKA_2 670 676 PF00069 0.470
MOD_PKA_2 693 699 PF00069 0.394
MOD_PKA_2 740 746 PF00069 0.300
MOD_PKA_2 841 847 PF00069 0.536
MOD_PKB_1 1234 1242 PF00069 0.683
MOD_Plk_1 201 207 PF00069 0.280
MOD_Plk_1 370 376 PF00069 0.386
MOD_Plk_1 446 452 PF00069 0.412
MOD_Plk_1 555 561 PF00069 0.458
MOD_Plk_1 581 587 PF00069 0.455
MOD_Plk_1 643 649 PF00069 0.472
MOD_Plk_1 664 670 PF00069 0.470
MOD_Plk_1 81 87 PF00069 0.452
MOD_Plk_2-3 1405 1411 PF00069 0.444
MOD_Plk_2-3 88 94 PF00069 0.304
MOD_Plk_2-3 991 997 PF00069 0.353
MOD_Plk_4 1290 1296 PF00069 0.434
MOD_Plk_4 1395 1401 PF00069 0.464
MOD_Plk_4 143 149 PF00069 0.507
MOD_Plk_4 158 164 PF00069 0.393
MOD_Plk_4 201 207 PF00069 0.440
MOD_Plk_4 370 376 PF00069 0.472
MOD_Plk_4 420 426 PF00069 0.533
MOD_Plk_4 429 435 PF00069 0.427
MOD_Plk_4 483 489 PF00069 0.438
MOD_Plk_4 715 721 PF00069 0.454
MOD_Plk_4 800 806 PF00069 0.344
MOD_Plk_4 862 868 PF00069 0.411
MOD_Plk_4 914 920 PF00069 0.329
MOD_Plk_4 946 952 PF00069 0.352
MOD_Plk_4 995 1001 PF00069 0.354
MOD_ProDKin_1 328 334 PF00069 0.513
MOD_ProDKin_1 602 608 PF00069 0.399
MOD_ProDKin_1 767 773 PF00069 0.557
MOD_ProDKin_1 791 797 PF00069 0.433
MOD_ProDKin_1 881 887 PF00069 0.562
MOD_ProDKin_1 899 905 PF00069 0.569
MOD_SUMO_for_1 615 618 PF00179 0.215
MOD_SUMO_rev_2 231 237 PF00179 0.398
MOD_SUMO_rev_2 373 382 PF00179 0.561
MOD_SUMO_rev_2 432 440 PF00179 0.470
MOD_SUMO_rev_2 88 98 PF00179 0.381
TRG_DiLeu_BaEn_1 946 951 PF01217 0.480
TRG_DiLeu_BaEn_2 617 623 PF01217 0.417
TRG_DiLeu_BaEn_2 648 654 PF01217 0.240
TRG_DiLeu_BaEn_4 1058 1064 PF01217 0.436
TRG_DiLeu_BaLyEn_6 588 593 PF01217 0.528
TRG_DiLeu_LyEn_5 1219 1224 PF01217 0.590
TRG_DiLeu_LyEn_5 775 780 PF01217 0.259
TRG_ENDOCYTIC_2 1034 1037 PF00928 0.361
TRG_ENDOCYTIC_2 1060 1063 PF00928 0.355
TRG_ENDOCYTIC_2 1082 1085 PF00928 0.481
TRG_ENDOCYTIC_2 275 278 PF00928 0.240
TRG_ENDOCYTIC_2 321 324 PF00928 0.501
TRG_ENDOCYTIC_2 620 623 PF00928 0.528
TRG_ENDOCYTIC_2 635 638 PF00928 0.468
TRG_ENDOCYTIC_2 739 742 PF00928 0.387
TRG_ENDOCYTIC_2 777 780 PF00928 0.535
TRG_ER_diArg_1 1067 1070 PF00400 0.354
TRG_ER_diArg_1 1233 1236 PF00400 0.631
TRG_ER_diArg_1 1324 1326 PF00400 0.529
TRG_ER_diArg_1 1365 1367 PF00400 0.539
TRG_ER_diArg_1 1394 1396 PF00400 0.691
TRG_ER_diArg_1 214 217 PF00400 0.487
TRG_ER_diArg_1 40 42 PF00400 0.443
TRG_ER_diArg_1 892 895 PF00400 0.624
TRG_Pf-PMV_PEXEL_1 315 319 PF00026 0.436
TRG_Pf-PMV_PEXEL_1 978 982 PF00026 0.440

Homologs

Protein Taxonomy Sequence identity Coverage
A0A1X0P171 Trypanosomatidae 33% 100%
A0A3Q8IJB0 Leishmania donovani 61% 100%
A0A3R7R8G4 Trypanosoma rangeli 30% 100%
A0A3S5H6Z8 Leishmania donovani 61% 100%
A0A3S7WU91 Leishmania donovani 83% 100%
A0A3S7WU94 Leishmania donovani 54% 100%
A0A3S7WU95 Leishmania donovani 62% 100%
A4H8U6 Leishmania braziliensis 56% 100%
A4H8V5 Leishmania braziliensis 67% 100%
A4H8V7 Leishmania braziliensis 60% 100%
A4H8V8 Leishmania braziliensis 59% 100%
A4HPI4 Leishmania braziliensis 27% 100%
A4HX84 Leishmania infantum 54% 100%
A4HX85 Leishmania infantum 63% 100%
A4HX87 Leishmania infantum 84% 100%
C9ZM79 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM80 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM81 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZM82 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM83 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZM86 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZN26 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN41 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN43 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN44 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN45 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZN46 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZNA5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZNA6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 30% 100%
C9ZNH3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZNT1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZPZ6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZQ51 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ89 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZQ90 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZQ92 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
C9ZTS4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZTS5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
C9ZTS6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZUE6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWQ5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
C9ZWU1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZWU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
C9ZWY7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
C9ZZQ4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0U3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0A0W7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
D0A0X5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
D0A1S1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5D2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A5D5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A5U0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A5U1 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A7A0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 100%
D0A9R3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 100%
D0AAV3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 34% 100%
E9AQY1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 62% 100%
E9AQY2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 66% 100%
E9AQY4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 65% 100%
E9ARD7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 57% 100%
Q25263 Leishmania donovani 62% 100%
Q26721 Trypanosoma brucei brucei 35% 100%
Q27675 Leishmania donovani 54% 100%
Q4QEH9 Leishmania major 64% 100%
Q4QEI0 Leishmania major 64% 100%
Q4QEI1 Leishmania major 64% 100%
Q4QEI2 Leishmania major 81% 100%
Q4QEI3 Leishmania major 56% 100%
Q99279 Trypanosoma brucei brucei 29% 100%
Q99280 Trypanosoma brucei brucei 32% 100%
V5AYH7 Trypanosoma cruzi 34% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS