BEACH-type PH domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AQW5_LEIMU

TriTrypDb:

LmxM.16.1520

Length:

1148

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0031298	replication fork protection complex	3	1
GO:0032991	protein-containing complex	1	1
GO:0140513	nuclear protein-containing complex	2	1

Expansion

Sequence features

E9AQW5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQW5

Function

Biological processes
Term	Name	Level	Count
GO:0000075	cell cycle checkpoint signaling	4	1
GO:0000076	DNA replication checkpoint signaling	6	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006259	DNA metabolic process	4	1
GO:0006275	regulation of DNA replication	6	1
GO:0006281	DNA repair	5	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0007165	signal transduction	2	1
GO:0008152	metabolic process	1	1
GO:0008156	negative regulation of DNA replication	7	1
GO:0009892	negative regulation of metabolic process	4	1
GO:0009987	cellular process	1	1
GO:0010564	regulation of cell cycle process	5	1
GO:0010605	negative regulation of macromolecule metabolic process	5	1
GO:0010948	negative regulation of cell cycle process	6	1
GO:0019219	regulation of nucleobase-containing compound metabolic process	5	1
GO:0019222	regulation of metabolic process	3	1
GO:0031323	regulation of cellular metabolic process	4	1
GO:0031324	negative regulation of cellular metabolic process	5	1
GO:0031570	DNA integrity checkpoint signaling	5	1
GO:0033554	cellular response to stress	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0035556	intracellular signal transduction	3	1
GO:0043111	replication fork arrest	6	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0045005	DNA-templated DNA replication maintenance of fidelity	5	1
GO:0045786	negative regulation of cell cycle	5	1
GO:0045934	negative regulation of nucleobase-containing compound metabolic process	6	1
GO:0046483	heterocycle metabolic process	3	1
GO:0048478	obsolete replication fork protection	6	1
GO:0048519	negative regulation of biological process	3	1
GO:0048523	negative regulation of cellular process	4	1
GO:0050789	regulation of biological process	2	1
GO:0050794	regulation of cellular process	3	1
GO:0050896	response to stimulus	1	1
GO:0051052	regulation of DNA metabolic process	5	1
GO:0051053	negative regulation of DNA metabolic process	6	1
GO:0051171	regulation of nitrogen compound metabolic process	4	1
GO:0051172	negative regulation of nitrogen compound metabolic process	5	1
GO:0051716	cellular response to stimulus	2	1
GO:0051726	regulation of cell cycle	4	1
GO:0060255	regulation of macromolecule metabolic process	4	1
GO:0065007	biological regulation	1	1
GO:0071704	organic substance metabolic process	2	1
GO:0080090	regulation of primary metabolic process	4	1
GO:0090304	nucleic acid metabolic process	4	1
GO:0090329	regulation of DNA-templated DNA replication	7	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901987	regulation of cell cycle phase transition	6	1
GO:1901988	negative regulation of cell cycle phase transition	7	1
GO:2000104	negative regulation of DNA-templated DNA replication	8	1

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	1
GO:0003677	DNA binding	4	1
GO:0005488	binding	1	1
GO:0097159	organic cyclic compound binding	2	1
GO:1901363	heterocyclic compound binding	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1037	1041	PF00656	0.763
CLV_C14_Caspase3-7	1064	1068	PF00656	0.663
CLV_C14_Caspase3-7	1091	1095	PF00656	0.666
CLV_C14_Caspase3-7	1104	1108	PF00656	0.659
CLV_C14_Caspase3-7	727	731	PF00656	0.672
CLV_NRD_NRD_1	1024	1026	PF00675	0.676
CLV_NRD_NRD_1	1027	1029	PF00675	0.676
CLV_NRD_NRD_1	1076	1078	PF00675	0.773
CLV_NRD_NRD_1	1088	1090	PF00675	0.834
CLV_NRD_NRD_1	442	444	PF00675	0.517
CLV_NRD_NRD_1	604	606	PF00675	0.405
CLV_NRD_NRD_1	666	668	PF00675	0.520
CLV_NRD_NRD_1	671	673	PF00675	0.420
CLV_NRD_NRD_1	759	761	PF00675	0.686
CLV_PCSK_FUR_1	1025	1029	PF00082	0.662
CLV_PCSK_KEX2_1	1002	1004	PF00082	0.770
CLV_PCSK_KEX2_1	1024	1026	PF00082	0.659
CLV_PCSK_KEX2_1	1027	1029	PF00082	0.657
CLV_PCSK_KEX2_1	1071	1073	PF00082	0.770
CLV_PCSK_KEX2_1	1075	1077	PF00082	0.776
CLV_PCSK_KEX2_1	1086	1088	PF00082	0.798
CLV_PCSK_KEX2_1	176	178	PF00082	0.447
CLV_PCSK_KEX2_1	444	446	PF00082	0.509
CLV_PCSK_KEX2_1	603	605	PF00082	0.397
CLV_PCSK_KEX2_1	666	668	PF00082	0.474
CLV_PCSK_KEX2_1	7	9	PF00082	0.504
CLV_PCSK_KEX2_1	701	703	PF00082	0.571
CLV_PCSK_KEX2_1	759	761	PF00082	0.572
CLV_PCSK_PC1ET2_1	1002	1004	PF00082	0.770
CLV_PCSK_PC1ET2_1	1071	1073	PF00082	0.770
CLV_PCSK_PC1ET2_1	1075	1077	PF00082	0.776
CLV_PCSK_PC1ET2_1	1086	1088	PF00082	0.798
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.447
CLV_PCSK_PC1ET2_1	444	446	PF00082	0.580
CLV_PCSK_PC1ET2_1	7	9	PF00082	0.504
CLV_PCSK_PC1ET2_1	701	703	PF00082	0.603
CLV_PCSK_PC7_1	1072	1078	PF00082	0.707
CLV_PCSK_SKI1_1	1028	1032	PF00082	0.753
CLV_PCSK_SKI1_1	1054	1058	PF00082	0.794
CLV_PCSK_SKI1_1	147	151	PF00082	0.570
CLV_PCSK_SKI1_1	447	451	PF00082	0.566
CLV_PCSK_SKI1_1	546	550	PF00082	0.512
CLV_PCSK_SKI1_1	553	557	PF00082	0.547
CLV_PCSK_SKI1_1	594	598	PF00082	0.379
CLV_PCSK_SKI1_1	655	659	PF00082	0.455
CLV_PCSK_SKI1_1	8	12	PF00082	0.454
CLV_PCSK_SKI1_1	823	827	PF00082	0.674
CLV_PCSK_SKI1_1	897	901	PF00082	0.460
CLV_PCSK_SKI1_1	964	968	PF00082	0.513
CLV_Separin_Metazoa	740	744	PF03568	0.666
DEG_APCC_DBOX_1	1002	1010	PF00400	0.584
DEG_APCC_DBOX_1	545	553	PF00400	0.470
DEG_APCC_DBOX_1	7	15	PF00400	0.480
DEG_APCC_DBOX_1	822	830	PF00400	0.706
DEG_SPOP_SBC_1	1033	1037	PF00917	0.637
DEG_SPOP_SBC_1	24	28	PF00917	0.500
DOC_AGCK_PIF_1	677	682	PF00069	0.464
DOC_CKS1_1	1131	1136	PF01111	0.504
DOC_CYCLIN_RxL_1	961	971	PF00134	0.528
DOC_CYCLIN_yClb5_NLxxxL_5	530	539	PF00134	0.252
DOC_CYCLIN_yCln2_LP_2	105	111	PF00134	0.478
DOC_MAPK_gen_1	502	512	PF00069	0.485
DOC_MAPK_gen_1	600	610	PF00069	0.469
DOC_MAPK_gen_1	7	14	PF00069	0.561
DOC_MAPK_MEF2A_6	104	111	PF00069	0.527
DOC_MAPK_MEF2A_6	127	136	PF00069	0.399
DOC_MAPK_MEF2A_6	184	192	PF00069	0.401
DOC_MAPK_MEF2A_6	217	225	PF00069	0.393
DOC_MAPK_MEF2A_6	264	273	PF00069	0.773
DOC_MAPK_MEF2A_6	603	612	PF00069	0.492
DOC_MAPK_MEF2A_6	650	658	PF00069	0.420
DOC_MAPK_MEF2A_6	7	14	PF00069	0.561
DOC_MAPK_NFAT4_5	7	15	PF00069	0.564
DOC_MAPK_RevD_3	163	177	PF00069	0.405
DOC_PP1_RVXF_1	653	659	PF00149	0.461
DOC_PP2B_LxvP_1	105	108	PF13499	0.475
DOC_PP2B_LxvP_1	134	137	PF13499	0.454
DOC_PP2B_LxvP_1	697	700	PF13499	0.546
DOC_PP4_FxxP_1	921	924	PF00568	0.433
DOC_USP7_MATH_1	241	245	PF00917	0.644
DOC_USP7_MATH_1	25	29	PF00917	0.393
DOC_USP7_MATH_1	299	303	PF00917	0.657
DOC_USP7_MATH_1	338	342	PF00917	0.480
DOC_USP7_MATH_1	398	402	PF00917	0.609
DOC_USP7_MATH_1	642	646	PF00917	0.410
DOC_USP7_MATH_1	700	704	PF00917	0.635
DOC_USP7_UBL2_3	1071	1075	PF12436	0.623
DOC_USP7_UBL2_3	383	387	PF12436	0.644
DOC_USP7_UBL2_3	690	694	PF12436	0.495
DOC_USP7_UBL2_3	704	708	PF12436	0.565
DOC_WW_Pin1_4	1015	1020	PF00397	0.671
DOC_WW_Pin1_4	1057	1062	PF00397	0.631
DOC_WW_Pin1_4	1130	1135	PF00397	0.503
DOC_WW_Pin1_4	361	366	PF00397	0.721
DOC_WW_Pin1_4	454	459	PF00397	0.680
DOC_WW_Pin1_4	522	527	PF00397	0.587
DOC_WW_Pin1_4	843	848	PF00397	0.535
LIG_14-3-3_CanoR_1	1054	1060	PF00244	0.512
LIG_14-3-3_CanoR_1	138	145	PF00244	0.588
LIG_14-3-3_CanoR_1	23	31	PF00244	0.402
LIG_14-3-3_CanoR_1	367	373	PF00244	0.666
LIG_14-3-3_CanoR_1	407	413	PF00244	0.666
LIG_14-3-3_CanoR_1	808	816	PF00244	0.649
LIG_14-3-3_CanoR_1	933	938	PF00244	0.637
LIG_Actin_WH2_2	535	552	PF00022	0.369
LIG_APCC_ABBAyCdc20_2	277	283	PF00400	0.709
LIG_BIR_II_1	1	5	PF00653	0.492
LIG_BIR_III_4	1067	1071	PF00653	0.511
LIG_BRCT_BRCA1_1	1017	1021	PF00533	0.610
LIG_BRCT_BRCA1_1	27	31	PF00533	0.518
LIG_BRCT_BRCA1_1	478	482	PF00533	0.494
LIG_BRCT_BRCA1_1	837	841	PF00533	0.530
LIG_BRCT_BRCA1_1	884	888	PF00533	0.534
LIG_Clathr_ClatBox_1	11	15	PF01394	0.559
LIG_deltaCOP1_diTrp_1	325	331	PF00928	0.439
LIG_deltaCOP1_diTrp_1	386	390	PF00928	0.705
LIG_EH1_1	218	226	PF00400	0.492
LIG_EH1_1	872	880	PF00400	0.489
LIG_eIF4E_1	614	620	PF01652	0.460
LIG_eIF4E_1	693	699	PF01652	0.508
LIG_FHA_1	1115	1121	PF00498	0.699
LIG_FHA_1	177	183	PF00498	0.572
LIG_FHA_1	196	202	PF00498	0.398
LIG_FHA_1	206	212	PF00498	0.536
LIG_FHA_1	47	53	PF00498	0.570
LIG_FHA_1	522	528	PF00498	0.589
LIG_FHA_1	554	560	PF00498	0.456
LIG_FHA_1	679	685	PF00498	0.453
LIG_FHA_1	779	785	PF00498	0.510
LIG_FHA_1	89	95	PF00498	0.473
LIG_FHA_1	961	967	PF00498	0.635
LIG_FHA_2	1113	1119	PF00498	0.756
LIG_FHA_2	1122	1128	PF00498	0.621
LIG_FHA_2	176	182	PF00498	0.543
LIG_FHA_2	973	979	PF00498	0.647
LIG_FHA_2	999	1005	PF00498	0.523
LIG_GBD_Chelix_1	611	619	PF00786	0.377
LIG_IRF3_LxIS_1	14	20	PF10401	0.561
LIG_KLC1_Yacidic_2	973	978	PF13176	0.642
LIG_LIR_Apic_2	341	347	PF02991	0.541
LIG_LIR_Apic_2	920	924	PF02991	0.454
LIG_LIR_Gen_1	160	171	PF02991	0.399
LIG_LIR_Gen_1	421	428	PF02991	0.664
LIG_LIR_Gen_1	475	485	PF02991	0.427
LIG_LIR_Gen_1	489	498	PF02991	0.424
LIG_LIR_Gen_1	529	539	PF02991	0.467
LIG_LIR_Gen_1	565	571	PF02991	0.632
LIG_LIR_Gen_1	582	593	PF02991	0.417
LIG_LIR_Gen_1	681	688	PF02991	0.469
LIG_LIR_Gen_1	838	847	PF02991	0.535
LIG_LIR_Gen_1	851	862	PF02991	0.527
LIG_LIR_Gen_1	91	101	PF02991	0.458
LIG_LIR_Gen_1	971	982	PF02991	0.513
LIG_LIR_Gen_1	987	996	PF02991	0.597
LIG_LIR_LC3C_4	103	107	PF02991	0.487
LIG_LIR_LC3C_4	222	227	PF02991	0.445
LIG_LIR_Nem_3	159	165	PF02991	0.396
LIG_LIR_Nem_3	385	391	PF02991	0.575
LIG_LIR_Nem_3	421	426	PF02991	0.723
LIG_LIR_Nem_3	475	480	PF02991	0.414
LIG_LIR_Nem_3	489	493	PF02991	0.387
LIG_LIR_Nem_3	529	535	PF02991	0.530
LIG_LIR_Nem_3	582	588	PF02991	0.369
LIG_LIR_Nem_3	681	685	PF02991	0.465
LIG_LIR_Nem_3	786	792	PF02991	0.740
LIG_LIR_Nem_3	838	844	PF02991	0.494
LIG_LIR_Nem_3	851	857	PF02991	0.463
LIG_LIR_Nem_3	884	890	PF02991	0.535
LIG_LIR_Nem_3	952	956	PF02991	0.474
LIG_LIR_Nem_3	971	977	PF02991	0.382
LIG_LIR_Nem_3	987	991	PF02991	0.586
LIG_MAD2	916	924	PF02301	0.527
LIG_MLH1_MIPbox_1	837	841	PF16413	0.530
LIG_MLH1_MIPbox_1	884	888	PF16413	0.565
LIG_NRBOX	124	130	PF00104	0.394
LIG_NRBOX	368	374	PF00104	0.659
LIG_NRBOX	621	627	PF00104	0.488
LIG_PCNA_yPIPBox_3	308	322	PF02747	0.462
LIG_Pex14_2	566	570	PF04695	0.488
LIG_Pex14_2	888	892	PF04695	0.437
LIG_Pex14_2	922	926	PF04695	0.518
LIG_PTB_Apo_2	226	233	PF02174	0.402
LIG_PTB_Apo_2	886	893	PF02174	0.455
LIG_PTB_Apo_2	920	927	PF02174	0.471
LIG_PTB_Phospho_1	226	232	PF10480	0.394
LIG_REV1ctd_RIR_1	838	846	PF16727	0.570
LIG_SH2_CRK	232	236	PF00017	0.581
LIG_SH2_CRK	532	536	PF00017	0.505
LIG_SH2_CRK	541	545	PF00017	0.459
LIG_SH2_CRK	854	858	PF00017	0.526
LIG_SH2_CRK	988	992	PF00017	0.688
LIG_SH2_GRB2like	532	535	PF00017	0.526
LIG_SH2_GRB2like	74	77	PF00017	0.712
LIG_SH2_NCK_1	64	68	PF00017	0.585
LIG_SH2_NCK_1	988	992	PF00017	0.688
LIG_SH2_PTP2	551	554	PF00017	0.429
LIG_SH2_STAP1	664	668	PF00017	0.606
LIG_SH2_STAT5	199	202	PF00017	0.490
LIG_SH2_STAT5	551	554	PF00017	0.443
LIG_SH2_STAT5	585	588	PF00017	0.432
LIG_SH2_STAT5	614	617	PF00017	0.358
LIG_SH2_STAT5	953	956	PF00017	0.575
LIG_SH2_STAT5	974	977	PF00017	0.601
LIG_SH2_STAT5	988	991	PF00017	0.690
LIG_SH3_3	1128	1134	PF00018	0.758
LIG_SH3_3	520	526	PF00018	0.551
LIG_SH3_3	565	571	PF00018	0.601
LIG_SUMO_SIM_anti_2	185	191	PF11976	0.388
LIG_SUMO_SIM_anti_2	222	228	PF11976	0.484
LIG_SUMO_SIM_anti_2	483	489	PF11976	0.420
LIG_SUMO_SIM_anti_2	606	613	PF11976	0.446
LIG_SUMO_SIM_anti_2	617	624	PF11976	0.417
LIG_SUMO_SIM_par_1	10	15	PF11976	0.552
LIG_SUMO_SIM_par_1	1055	1060	PF11976	0.512
LIG_SUMO_SIM_par_1	185	191	PF11976	0.414
LIG_SUMO_SIM_par_1	192	198	PF11976	0.397
LIG_SUMO_SIM_par_1	483	489	PF11976	0.471
LIG_SUMO_SIM_par_1	578	584	PF11976	0.411
LIG_SUMO_SIM_par_1	617	624	PF11976	0.447
LIG_TRAF2_1	347	350	PF00917	0.528
LIG_TRAF2_1	711	714	PF00917	0.587
LIG_TYR_ITIM	530	535	PF00017	0.432
LIG_TYR_ITIM	539	544	PF00017	0.400
LIG_TYR_ITIM	549	554	PF00017	0.421
LIG_TYR_ITIM	583	588	PF00017	0.446
LIG_TYR_ITIM	852	857	PF00017	0.509
LIG_TYR_ITIM	972	977	PF00017	0.649
LIG_UBA3_1	121	127	PF00899	0.399
LIG_UBA3_1	149	154	PF00899	0.549
LIG_WRC_WIRS_1	477	482	PF05994	0.488
LIG_WRC_WIRS_1	487	492	PF05994	0.443
LIG_WRC_WIRS_1	593	598	PF05994	0.482
LIG_WRC_WIRS_1	679	684	PF05994	0.465
MOD_CDC14_SPxK_1	364	367	PF00782	0.652
MOD_CDK_SPK_2	843	848	PF00069	0.535
MOD_CDK_SPxK_1	361	367	PF00069	0.653
MOD_CK1_1	1015	1021	PF00069	0.748
MOD_CK1_1	1032	1038	PF00069	0.776
MOD_CK1_1	26	32	PF00069	0.515
MOD_CK1_1	300	306	PF00069	0.625
MOD_CK1_1	361	367	PF00069	0.712
MOD_CK1_1	409	415	PF00069	0.729
MOD_CK1_1	486	492	PF00069	0.491
MOD_CK1_1	662	668	PF00069	0.480
MOD_CK1_1	728	734	PF00069	0.708
MOD_CK1_1	766	772	PF00069	0.741
MOD_CK1_1	817	823	PF00069	0.662
MOD_CK1_1	827	833	PF00069	0.566
MOD_CK2_1	1043	1049	PF00069	0.744
MOD_CK2_1	1112	1118	PF00069	0.751
MOD_CK2_1	1121	1127	PF00069	0.741
MOD_CK2_1	137	143	PF00069	0.578
MOD_CK2_1	175	181	PF00069	0.505
MOD_CK2_1	26	32	PF00069	0.582
MOD_CK2_1	708	714	PF00069	0.577
MOD_CK2_1	828	834	PF00069	0.553
MOD_CK2_1	86	92	PF00069	0.589
MOD_CK2_1	972	978	PF00069	0.539
MOD_CK2_1	998	1004	PF00069	0.496
MOD_Cter_Amidation	1069	1072	PF01082	0.519
MOD_GlcNHglycan	1	4	PF01048	0.627
MOD_GlcNHglycan	1031	1034	PF01048	0.813
MOD_GlcNHglycan	1100	1106	PF01048	0.804
MOD_GlcNHglycan	1109	1112	PF01048	0.739
MOD_GlcNHglycan	139	142	PF01048	0.518
MOD_GlcNHglycan	266	269	PF01048	0.767
MOD_GlcNHglycan	297	300	PF01048	0.648
MOD_GlcNHglycan	409	412	PF01048	0.712
MOD_GlcNHglycan	577	580	PF01048	0.526
MOD_GlcNHglycan	710	713	PF01048	0.572
MOD_GlcNHglycan	730	733	PF01048	0.698
MOD_GlcNHglycan	778	781	PF01048	0.762
MOD_GlcNHglycan	794	797	PF01048	0.578
MOD_GlcNHglycan	837	840	PF01048	0.588
MOD_GlcNHglycan	943	946	PF01048	0.635
MOD_GlcNHglycan	947	950	PF01048	0.573
MOD_GSK3_1	1028	1035	PF00069	0.820
MOD_GSK3_1	1039	1046	PF00069	0.725
MOD_GSK3_1	152	159	PF00069	0.563
MOD_GSK3_1	293	300	PF00069	0.634
MOD_GSK3_1	357	364	PF00069	0.647
MOD_GSK3_1	407	414	PF00069	0.754
MOD_GSK3_1	468	475	PF00069	0.561
MOD_GSK3_1	522	529	PF00069	0.527
MOD_GSK3_1	558	565	PF00069	0.555
MOD_GSK3_1	575	582	PF00069	0.319
MOD_GSK3_1	588	595	PF00069	0.364
MOD_GSK3_1	763	770	PF00069	0.746
MOD_GSK3_1	803	810	PF00069	0.726
MOD_GSK3_1	814	821	PF00069	0.611
MOD_GSK3_1	824	831	PF00069	0.599
MOD_GSK3_1	848	855	PF00069	0.515
MOD_GSK3_1	941	948	PF00069	0.634
MOD_GSK3_1	956	963	PF00069	0.521
MOD_GSK3_1	968	975	PF00069	0.568
MOD_LATS_1	262	268	PF00433	0.716
MOD_N-GLC_1	1107	1112	PF02516	0.690
MOD_N-GLC_1	115	120	PF02516	0.458
MOD_N-GLC_1	230	235	PF02516	0.488
MOD_N-GLC_1	473	478	PF02516	0.420
MOD_N-GLC_1	848	853	PF02516	0.509
MOD_N-GLC_1	967	972	PF02516	0.554
MOD_N-GLC_1	996	1001	PF02516	0.689
MOD_NEK2_1	117	122	PF00069	0.445
MOD_NEK2_1	17	22	PF00069	0.411
MOD_NEK2_1	297	302	PF00069	0.610
MOD_NEK2_1	488	493	PF00069	0.388
MOD_NEK2_1	588	593	PF00069	0.460
MOD_NEK2_1	621	626	PF00069	0.399
MOD_NEK2_1	643	648	PF00069	0.379
MOD_NEK2_1	680	685	PF00069	0.364
MOD_NEK2_1	763	768	PF00069	0.808
MOD_NEK2_1	792	797	PF00069	0.559
MOD_NEK2_1	852	857	PF00069	0.435
MOD_NEK2_1	874	879	PF00069	0.392
MOD_NEK2_1	956	961	PF00069	0.514
MOD_NEK2_1	967	972	PF00069	0.547
MOD_NEK2_1	986	991	PF00069	0.531
MOD_NEK2_2	418	423	PF00069	0.729
MOD_PIKK_1	1034	1040	PF00454	0.806
MOD_PIKK_1	808	814	PF00454	0.756
MOD_PK_1	933	939	PF00069	0.618
MOD_PKA_1	176	182	PF00069	0.482
MOD_PKA_1	382	388	PF00069	0.644
MOD_PKA_2	1026	1032	PF00069	0.721
MOD_PKA_2	1038	1044	PF00069	0.740
MOD_PKA_2	1078	1084	PF00069	0.718
MOD_PKA_2	137	143	PF00069	0.578
MOD_PKA_2	176	182	PF00069	0.482
MOD_PKA_2	300	306	PF00069	0.662
MOD_PKA_2	406	412	PF00069	0.640
MOD_PKA_2	501	507	PF00069	0.517
MOD_PKA_2	807	813	PF00069	0.769
MOD_PKA_2	960	966	PF00069	0.624
MOD_Plk_1	1004	1010	PF00069	0.756
MOD_Plk_1	230	236	PF00069	0.523
MOD_Plk_1	293	299	PF00069	0.704
MOD_Plk_1	46	52	PF00069	0.540
MOD_Plk_1	473	479	PF00069	0.419
MOD_Plk_1	606	612	PF00069	0.523
MOD_Plk_1	763	769	PF00069	0.684
MOD_Plk_1	821	827	PF00069	0.701
MOD_Plk_1	848	854	PF00069	0.490
MOD_Plk_1	956	962	PF00069	0.484
MOD_Plk_1	967	973	PF00069	0.510
MOD_Plk_2-3	284	290	PF00069	0.650
MOD_Plk_2-3	725	731	PF00069	0.729
MOD_Plk_2-3	735	741	PF00069	0.689
MOD_Plk_4	117	123	PF00069	0.434
MOD_Plk_4	192	198	PF00069	0.403
MOD_Plk_4	26	32	PF00069	0.520
MOD_Plk_4	338	344	PF00069	0.482
MOD_Plk_4	352	358	PF00069	0.571
MOD_Plk_4	368	374	PF00069	0.649
MOD_Plk_4	418	424	PF00069	0.625
MOD_Plk_4	473	479	PF00069	0.340
MOD_Plk_4	483	489	PF00069	0.398
MOD_Plk_4	526	532	PF00069	0.378
MOD_Plk_4	562	568	PF00069	0.566
MOD_Plk_4	606	612	PF00069	0.358
MOD_Plk_4	621	627	PF00069	0.375
MOD_Plk_4	643	649	PF00069	0.382
MOD_Plk_4	869	875	PF00069	0.480
MOD_Plk_4	882	888	PF00069	0.433
MOD_Plk_4	933	939	PF00069	0.649
MOD_Plk_4	949	955	PF00069	0.363
MOD_Plk_4	972	978	PF00069	0.543
MOD_ProDKin_1	1015	1021	PF00069	0.674
MOD_ProDKin_1	1057	1063	PF00069	0.629
MOD_ProDKin_1	1130	1136	PF00069	0.504
MOD_ProDKin_1	361	367	PF00069	0.722
MOD_ProDKin_1	454	460	PF00069	0.669
MOD_ProDKin_1	522	528	PF00069	0.586
MOD_ProDKin_1	843	849	PF00069	0.529
MOD_SUMO_for_1	559	562	PF00179	0.528
MOD_SUMO_rev_2	501	510	PF00179	0.560
MOD_SUMO_rev_2	595	602	PF00179	0.475
MOD_SUMO_rev_2	769	778	PF00179	0.744
MOD_SUMO_rev_2	973	982	PF00179	0.506
TRG_DiLeu_BaEn_1	161	166	PF01217	0.410
TRG_DiLeu_BaEn_1	617	622	PF01217	0.443
TRG_DiLeu_BaEn_2	561	567	PF01217	0.579
TRG_DiLeu_BaEn_4	349	355	PF01217	0.538
TRG_DiLeu_BaLyEn_6	105	110	PF01217	0.397
TRG_DiLeu_BaLyEn_6	40	45	PF01217	0.532
TRG_ENDOCYTIC_2	232	235	PF00928	0.487
TRG_ENDOCYTIC_2	453	456	PF00928	0.701
TRG_ENDOCYTIC_2	532	535	PF00928	0.431
TRG_ENDOCYTIC_2	541	544	PF00928	0.330
TRG_ENDOCYTIC_2	551	554	PF00928	0.251
TRG_ENDOCYTIC_2	585	588	PF00928	0.432
TRG_ENDOCYTIC_2	854	857	PF00928	0.517
TRG_ENDOCYTIC_2	919	922	PF00928	0.439
TRG_ENDOCYTIC_2	953	956	PF00928	0.575
TRG_ENDOCYTIC_2	974	977	PF00928	0.497
TRG_ENDOCYTIC_2	988	991	PF00928	0.607
TRG_ER_diArg_1	1024	1027	PF00400	0.677
TRG_ER_diArg_1	1076	1079	PF00400	0.762
TRG_ER_diArg_1	1087	1089	PF00400	0.683
TRG_ER_diArg_1	40	43	PF00400	0.414
TRG_ER_diArg_1	442	445	PF00400	0.536
TRG_ER_diArg_1	48	51	PF00400	0.454
TRG_ER_diArg_1	602	605	PF00400	0.406
TRG_ER_diArg_1	666	668	PF00400	0.474
TRG_ER_diArg_1	759	761	PF00400	0.572
TRG_NLS_Bipartite_1	1071	1090	PF00514	0.770
TRG_NLS_MonoCore_2	1084	1089	PF00514	0.775
TRG_NLS_MonoExtC_3	1074	1079	PF00514	0.769
TRG_NLS_MonoExtC_3	1084	1089	PF00514	0.817
TRG_NLS_MonoExtC_3	442	447	PF00514	0.575
TRG_NLS_MonoExtN_4	1072	1079	PF00514	0.777
TRG_NLS_MonoExtN_4	1085	1090	PF00514	0.829
TRG_NLS_MonoExtN_4	443	448	PF00514	0.563
TRG_NLS_MonoExtN_4	700	705	PF00514	0.592
TRG_Pf-PMV_PEXEL_1	308	312	PF00026	0.671
TRG_Pf-PMV_PEXEL_1	43	47	PF00026	0.428
TRG_Pf-PMV_PEXEL_1	553	557	PF00026	0.502

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC20	Leptomonas seymouri	60%	100%
A0A3S7WU73	Leishmania donovani	91%	100%
A0A422N424	Trypanosoma rangeli	41%	100%
A4H8T1	Leishmania braziliensis	77%	100%
A4HX50	Leishmania infantum	91%	100%
C9ZVU2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
Q4QEL3	Leishmania major	90%	100%
V5BS96	Trypanosoma cruzi	41%	100%