Mitochondrial RNA binding complex 1 subunit

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AQW3_LEIMU

TriTrypDb:

LmxM.16.1500

Length:

572

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQW3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQW3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	357	361	PF00656	0.715
CLV_C14_Caspase3-7	418	422	PF00656	0.558
CLV_C14_Caspase3-7	461	465	PF00656	0.451
CLV_NRD_NRD_1	139	141	PF00675	0.424
CLV_NRD_NRD_1	147	149	PF00675	0.404
CLV_NRD_NRD_1	216	218	PF00675	0.500
CLV_NRD_NRD_1	3	5	PF00675	0.635
CLV_NRD_NRD_1	477	479	PF00675	0.529
CLV_NRD_NRD_1	48	50	PF00675	0.434
CLV_NRD_NRD_1	558	560	PF00675	0.508
CLV_NRD_NRD_1	569	571	PF00675	0.505
CLV_PCSK_KEX2_1	11	13	PF00082	0.535
CLV_PCSK_KEX2_1	139	141	PF00082	0.526
CLV_PCSK_KEX2_1	147	149	PF00082	0.473
CLV_PCSK_KEX2_1	216	218	PF00082	0.566
CLV_PCSK_KEX2_1	3	5	PF00082	0.595
CLV_PCSK_KEX2_1	31	33	PF00082	0.385
CLV_PCSK_KEX2_1	477	479	PF00082	0.529
CLV_PCSK_KEX2_1	48	50	PF00082	0.420
CLV_PCSK_KEX2_1	558	560	PF00082	0.508
CLV_PCSK_KEX2_1	569	571	PF00082	0.505
CLV_PCSK_PC1ET2_1	11	13	PF00082	0.581
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.385
CLV_PCSK_SKI1_1	267	271	PF00082	0.419
CLV_PCSK_SKI1_1	309	313	PF00082	0.412
CLV_PCSK_SKI1_1	463	467	PF00082	0.616
CLV_PCSK_SKI1_1	477	481	PF00082	0.480
CLV_PCSK_SKI1_1	547	551	PF00082	0.574
CLV_PCSK_SKI1_1	66	70	PF00082	0.497
CLV_PCSK_SKI1_1	74	78	PF00082	0.453
CLV_Separin_Metazoa	223	227	PF03568	0.437
DEG_APCC_DBOX_1	476	484	PF00400	0.509
DEG_Nend_Nbox_1	1	3	PF02207	0.563
DOC_ANK_TNKS_1	326	333	PF00023	0.389
DOC_CYCLIN_RxL_1	61	72	PF00134	0.567
DOC_MAPK_gen_1	147	153	PF00069	0.519
DOC_MAPK_gen_1	3	9	PF00069	0.558
DOC_MAPK_gen_1	84	94	PF00069	0.539
DOC_MAPK_MEF2A_6	87	95	PF00069	0.527
DOC_PP1_RVXF_1	307	313	PF00149	0.262
DOC_PP2B_LxvP_1	343	346	PF13499	0.469
DOC_USP7_MATH_1	346	350	PF00917	0.507
DOC_USP7_MATH_1	383	387	PF00917	0.616
DOC_USP7_MATH_1	398	402	PF00917	0.594
DOC_WW_Pin1_4	10	15	PF00397	0.561
DOC_WW_Pin1_4	173	178	PF00397	0.470
DOC_WW_Pin1_4	193	198	PF00397	0.439
DOC_WW_Pin1_4	315	320	PF00397	0.430
DOC_WW_Pin1_4	374	379	PF00397	0.714
LIG_14-3-3_CanoR_1	170	178	PF00244	0.555
LIG_14-3-3_CanoR_1	20	25	PF00244	0.462
LIG_14-3-3_CanoR_1	249	255	PF00244	0.461
LIG_14-3-3_CanoR_1	283	289	PF00244	0.421
LIG_14-3-3_CanoR_1	3	8	PF00244	0.627
LIG_14-3-3_CanoR_1	344	352	PF00244	0.607
LIG_14-3-3_CanoR_1	558	568	PF00244	0.569
LIG_Actin_WH2_2	236	251	PF00022	0.462
LIG_APCC_ABBA_1	326	331	PF00400	0.413
LIG_APCC_ABBA_1	436	441	PF00400	0.526
LIG_BRCT_BRCA1_1	313	317	PF00533	0.516
LIG_CtBP_PxDLS_1	177	181	PF00389	0.432
LIG_CtBP_PxDLS_1	378	382	PF00389	0.542
LIG_DLG_GKlike_1	20	27	PF00625	0.644
LIG_FHA_1	179	185	PF00498	0.504
LIG_FHA_1	204	210	PF00498	0.431
LIG_FHA_1	283	289	PF00498	0.497
LIG_FHA_1	293	299	PF00498	0.548
LIG_FHA_1	346	352	PF00498	0.737
LIG_FHA_1	464	470	PF00498	0.498
LIG_FHA_1	491	497	PF00498	0.572
LIG_FHA_1	526	532	PF00498	0.565
LIG_FHA_1	560	566	PF00498	0.564
LIG_FHA_1	75	81	PF00498	0.492
LIG_FHA_2	159	165	PF00498	0.463
LIG_FHA_2	174	180	PF00498	0.414
LIG_FHA_2	23	29	PF00498	0.545
LIG_FHA_2	316	322	PF00498	0.409
LIG_GBD_Chelix_1	298	306	PF00786	0.532
LIG_KLC1_Yacidic_2	437	441	PF13176	0.239
LIG_LIR_Gen_1	115	125	PF02991	0.503
LIG_LIR_Gen_1	205	214	PF02991	0.508
LIG_LIR_Gen_1	424	433	PF02991	0.515
LIG_LIR_Nem_3	115	120	PF02991	0.486
LIG_LIR_Nem_3	143	149	PF02991	0.424
LIG_LIR_Nem_3	205	210	PF02991	0.506
LIG_LIR_Nem_3	424	429	PF02991	0.539
LIG_LIR_Nem_3	72	76	PF02991	0.406
LIG_LYPXL_SIV_4	425	433	PF13949	0.562
LIG_MYND_1	379	383	PF01753	0.441
LIG_NRBOX	495	501	PF00104	0.450
LIG_PCNA_PIPBox_1	432	441	PF02747	0.496
LIG_PCNA_yPIPBox_3	215	228	PF02747	0.465
LIG_Pex14_2	100	104	PF04695	0.410
LIG_SH2_CRK	146	150	PF00017	0.467
LIG_SH2_SRC	329	332	PF00017	0.444
LIG_SH2_SRC	439	442	PF00017	0.461
LIG_SH2_STAT5	16	19	PF00017	0.543
LIG_SH2_STAT5	329	332	PF00017	0.399
LIG_SH2_STAT5	34	37	PF00017	0.547
LIG_SH2_STAT5	426	429	PF00017	0.469
LIG_SH2_STAT5	439	442	PF00017	0.378
LIG_SH2_STAT5	75	78	PF00017	0.487
LIG_SH3_3	152	158	PF00018	0.546
LIG_SH3_3	218	224	PF00018	0.486
LIG_SUMO_SIM_anti_2	124	130	PF11976	0.448
LIG_SUMO_SIM_anti_2	240	246	PF11976	0.453
LIG_SUMO_SIM_anti_2	431	437	PF11976	0.514
LIG_SUMO_SIM_anti_2	90	96	PF11976	0.474
LIG_SUMO_SIM_par_1	331	337	PF11976	0.434
LIG_SUMO_SIM_par_1	492	498	PF11976	0.467
LIG_TRAF2_1	161	164	PF00917	0.475
LIG_TRAF2_1	522	525	PF00917	0.420
LIG_UBA3_1	487	492	PF00899	0.557
MOD_CK1_1	10	16	PF00069	0.559
MOD_CK1_1	22	28	PF00069	0.495
MOD_CK1_1	337	343	PF00069	0.519
MOD_CK1_1	368	374	PF00069	0.706
MOD_CK1_1	377	383	PF00069	0.651
MOD_CK1_1	401	407	PF00069	0.486
MOD_CK1_1	428	434	PF00069	0.471
MOD_CK2_1	158	164	PF00069	0.415
MOD_CK2_1	173	179	PF00069	0.433
MOD_CK2_1	20	26	PF00069	0.543
MOD_CK2_1	315	321	PF00069	0.402
MOD_CK2_1	428	434	PF00069	0.516
MOD_CK2_1	492	498	PF00069	0.457
MOD_CK2_1	52	58	PF00069	0.573
MOD_GlcNHglycan	289	292	PF01048	0.485
MOD_GlcNHglycan	336	339	PF01048	0.450
MOD_GlcNHglycan	348	351	PF01048	0.573
MOD_GlcNHglycan	357	360	PF01048	0.555
MOD_GlcNHglycan	370	373	PF01048	0.728
MOD_GlcNHglycan	385	388	PF01048	0.546
MOD_GlcNHglycan	412	415	PF01048	0.438
MOD_GlcNHglycan	421	424	PF01048	0.458
MOD_GlcNHglycan	458	461	PF01048	0.675
MOD_GlcNHglycan	510	513	PF01048	0.577
MOD_GlcNHglycan	537	540	PF01048	0.505
MOD_GSK3_1	277	284	PF00069	0.397
MOD_GSK3_1	3	10	PF00069	0.700
MOD_GSK3_1	311	318	PF00069	0.466
MOD_GSK3_1	355	362	PF00069	0.522
MOD_GSK3_1	373	380	PF00069	0.728
MOD_GSK3_1	421	428	PF00069	0.540
MOD_GSK3_1	454	461	PF00069	0.657
MOD_LATS_1	556	562	PF00433	0.553
MOD_NEK2_1	2	7	PF00069	0.555
MOD_NEK2_1	265	270	PF00069	0.279
MOD_NEK2_1	27	32	PF00069	0.568
MOD_NEK2_1	277	282	PF00069	0.393
MOD_NEK2_1	287	292	PF00069	0.470
MOD_NEK2_1	365	370	PF00069	0.691
MOD_NEK2_1	419	424	PF00069	0.532
MOD_NEK2_1	482	487	PF00069	0.383
MOD_PIKK_1	428	434	PF00454	0.483
MOD_PKA_1	3	9	PF00069	0.558
MOD_PKA_1	558	564	PF00069	0.581
MOD_PKA_2	19	25	PF00069	0.489
MOD_PKA_2	2	8	PF00069	0.590
MOD_PKA_2	282	288	PF00069	0.415
MOD_PKA_2	346	352	PF00069	0.600
MOD_PKA_2	558	564	PF00069	0.560
MOD_PKB_1	545	553	PF00069	0.589
MOD_Plk_2-3	159	165	PF00069	0.533
MOD_Plk_4	3	9	PF00069	0.635
MOD_ProDKin_1	10	16	PF00069	0.559
MOD_ProDKin_1	173	179	PF00069	0.475
MOD_ProDKin_1	193	199	PF00069	0.434
MOD_ProDKin_1	315	321	PF00069	0.422
MOD_ProDKin_1	374	380	PF00069	0.715
TRG_DiLeu_BaEn_1	124	129	PF01217	0.514
TRG_DiLeu_BaEn_1	498	503	PF01217	0.438
TRG_ENDOCYTIC_2	146	149	PF00928	0.422
TRG_ENDOCYTIC_2	426	429	PF00928	0.507
TRG_ENDOCYTIC_2	73	76	PF00928	0.400
TRG_ER_diArg_1	138	140	PF00400	0.511
TRG_ER_diArg_1	146	148	PF00400	0.475
TRG_ER_diArg_1	2	4	PF00400	0.612
TRG_ER_diArg_1	216	219	PF00400	0.556
TRG_ER_diArg_1	225	228	PF00400	0.526
TRG_ER_diArg_1	389	392	PF00400	0.651
TRG_ER_diArg_1	48	50	PF00400	0.420
TRG_ER_diArg_1	558	560	PF00400	0.495
TRG_ER_diArg_1	568	570	PF00400	0.446
TRG_NES_CRM1_1	321	331	PF08389	0.372
TRG_Pf-PMV_PEXEL_1	186	190	PF00026	0.510
TRG_Pf-PMV_PEXEL_1	391	396	PF00026	0.638
TRG_Pf-PMV_PEXEL_1	547	551	PF00026	0.598

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5T4	Leptomonas seymouri	66%	98%
A0A0S4IMI7	Bodo saltans	32%	98%
A0A1X0NYU8	Trypanosomatidae	41%	100%
A0A3Q8ICN8	Leishmania donovani	93%	100%
A0A422N437	Trypanosoma rangeli	40%	100%
A4H8S9	Leishmania braziliensis	84%	100%
A4HX48	Leishmania infantum	93%	100%
C9ZVU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
Q4QEL5	Leishmania major	93%	99%
V5B2M3	Trypanosoma cruzi	39%	100%