LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania mexicana
UniProt:
E9AQW2_LEIMU
TriTrypDb:
LmxM.16.1490
Length:
364

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQW2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQW2

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0003824 catalytic activity 1 3
GO:0016853 isomerase activity 2 3
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 270 274 PF00656 0.547
CLV_C14_Caspase3-7 278 282 PF00656 0.539
CLV_NRD_NRD_1 214 216 PF00675 0.445
CLV_NRD_NRD_1 219 221 PF00675 0.409
CLV_PCSK_KEX2_1 76 78 PF00082 0.538
CLV_PCSK_PC1ET2_1 76 78 PF00082 0.571
CLV_PCSK_SKI1_1 25 29 PF00082 0.341
CLV_PCSK_SKI1_1 329 333 PF00082 0.581
CLV_Separin_Metazoa 128 132 PF03568 0.503
DEG_MDM2_SWIB_1 19 27 PF02201 0.235
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P676 Leptomonas seymouri 65% 100%
A0A1X0NZ85 Trypanosomatidae 49% 100%
A0A3Q8I9J9 Leishmania donovani 93% 100%
A0A3R7KS20 Trypanosoma rangeli 46% 100%
A4H8S8 Leishmania braziliensis 82% 100%
A4HX47 Leishmania infantum 93% 100%
C9ZVU5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 43% 100%
Q4QEL6 Leishmania major 90% 100%
V5BI68 Trypanosoma cruzi 47% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS