Paraflagellar rod protein 2C

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

paraflagellar rod protein 2C

Species:

Leishmania mexicana

UniProt:

E9AQV5_LEIMU

TriTrypDb:

LmxM.16.1425partial

Length:

196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	2
GO:0031514	motile cilium	5	2
GO:0042995	cell projection	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0110165	cellular anatomical entity	1	2
GO:0120025	plasma membrane bounded cell projection	3	2

Expansion

Sequence features

E9AQV5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQV5

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0005515	protein binding	2	2
GO:0005516	calmodulin binding	3	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	149	151	PF00675	0.549
CLV_NRD_NRD_1	44	46	PF00675	0.549
CLV_NRD_NRD_1	68	70	PF00675	0.549
CLV_PCSK_KEX2_1	149	151	PF00082	0.549
CLV_PCSK_KEX2_1	176	178	PF00082	0.703
CLV_PCSK_KEX2_1	44	46	PF00082	0.549
CLV_PCSK_KEX2_1	59	61	PF00082	0.287
CLV_PCSK_PC1ET2_1	176	178	PF00082	0.703
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.549
CLV_PCSK_PC7_1	172	178	PF00082	0.703
DEG_Nend_UBRbox_1	1	3	PF02207	0.549
DOC_MAPK_gen_1	66	75	PF00069	0.549
DOC_MAPK_MEF2A_6	69	77	PF00069	0.549
DOC_MAPK_NFAT4_5	70	78	PF00069	0.549
DOC_PP4_FxxP_1	135	138	PF00568	0.549
DOC_USP7_UBL2_3	94	98	PF12436	0.549
LIG_14-3-3_CanoR_1	187	192	PF00244	0.772
LIG_14-3-3_CanoR_1	69	77	PF00244	0.549
LIG_APCC_ABBA_1	33	38	PF00400	0.549
LIG_APCC_ABBAyCdc20_2	32	38	PF00400	0.549
LIG_FHA_1	176	182	PF00498	0.709
LIG_FHA_2	22	28	PF00498	0.549
LIG_LIR_Apic_2	134	138	PF02991	0.549
LIG_LIR_Nem_3	41	46	PF02991	0.549
LIG_SH2_CRK	47	51	PF00017	0.549
LIG_SH2_SRC	39	42	PF00017	0.549
LIG_SH2_STAT5	39	42	PF00017	0.549
LIG_TRAF2_1	138	141	PF00917	0.549
LIG_TRAF2_1	161	164	PF00917	0.685
MOD_CK2_1	21	27	PF00069	0.549
MOD_GlcNHglycan	14	17	PF01048	0.339
MOD_GlcNHglycan	2	5	PF01048	0.549
MOD_NEK2_1	175	180	PF00069	0.705
MOD_PKA_1	87	93	PF00069	0.549
MOD_PKA_2	148	154	PF00069	0.549
MOD_PKA_2	68	74	PF00069	0.549
MOD_SUMO_for_1	161	164	PF00179	0.685
MOD_SUMO_for_1	92	95	PF00179	0.549
MOD_SUMO_rev_2	164	169	PF00179	0.702
MOD_SUMO_rev_2	171	178	PF00179	0.581
TRG_DiLeu_BaEn_3	104	110	PF01217	0.549
TRG_DiLeu_BaEn_4	105	111	PF01217	0.549
TRG_ENDOCYTIC_2	47	50	PF00928	0.549
TRG_ER_diArg_1	43	45	PF00400	0.549
TRG_Pf-PMV_PEXEL_1	59	63	PF00026	0.549

Homologs


Protein	Taxonomy	Sequence identity	Coverage
P22225	TRYBB	82%	33%
Q26789	TRYBB	61%	33%