Coatomer subunit delta

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

delta-coat protein, putative

Species:

Leishmania mexicana

UniProt:

E9AQS9_LEIMU

TriTrypDb:

LmxM.16.1180

Length:

536

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

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Cellular components
Term	Name	Level	Count
GO:0000139	Golgi membrane	5	12
GO:0005794	Golgi apparatus	5	1
GO:0016020	membrane	2	12
GO:0030117	membrane coat	3	12
GO:0030120	vesicle coat	4	12
GO:0030126	COPI vesicle coat	5	12
GO:0031090	organelle membrane	3	12
GO:0032991	protein-containing complex	1	12
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1

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Expansion

Sequence features

E9AQS9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQS9

Function

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Biological processes
Term	Name	Level	Count
GO:0006810	transport	3	12
GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	4	1
GO:0006890	retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum	6	12
GO:0008104	protein localization	4	12
GO:0009987	cellular process	1	12
GO:0015031	protein transport	4	12
GO:0016192	vesicle-mediated transport	4	12
GO:0033036	macromolecule localization	2	12
GO:0045184	establishment of protein localization	3	12
GO:0046907	intracellular transport	3	1

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Could not find GO molecular_function term for this entry.

Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	371	375	PF00656	0.373
CLV_C14_Caspase3-7	462	466	PF00656	0.474
CLV_C14_Caspase3-7	49	53	PF00656	0.455
CLV_NRD_NRD_1	166	168	PF00675	0.529
CLV_NRD_NRD_1	172	174	PF00675	0.592
CLV_NRD_NRD_1	251	253	PF00675	0.721
CLV_PCSK_FUR_1	170	174	PF00082	0.570
CLV_PCSK_KEX2_1	124	126	PF00082	0.456
CLV_PCSK_KEX2_1	172	174	PF00082	0.569
CLV_PCSK_PC1ET2_1	124	126	PF00082	0.472

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I039	Leptomonas seymouri	75%	100%
A0A0S4KK09	Bodo saltans	44%	100%
A0A1X0NYY5	Trypanosomatidae	51%	97%
A0A3Q8IAE4	Leishmania donovani	96%	100%
A0A422N6V7	Trypanosoma rangeli	51%	100%
A4H8P5	Leishmania braziliensis	87%	100%
A4HX15	Leishmania infantum	96%	100%
C9ZVY7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
P43621	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	98%
P48444	Homo sapiens	32%	100%

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