Myosin_tail_1 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania mexicana

UniProt:

E9AQQ7_LEIMU

TriTrypDb:

LmxM.16.0980

Length:

731

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQQ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQQ7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	102	106	PF00656	0.560
CLV_C14_Caspase3-7	648	652	PF00656	0.720
CLV_NRD_NRD_1	179	181	PF00675	0.600
CLV_NRD_NRD_1	19	21	PF00675	0.544
CLV_NRD_NRD_1	212	214	PF00675	0.670
CLV_NRD_NRD_1	274	276	PF00675	0.601
CLV_NRD_NRD_1	442	444	PF00675	0.532
CLV_NRD_NRD_1	450	452	PF00675	0.522
CLV_NRD_NRD_1	506	508	PF00675	0.601
CLV_NRD_NRD_1	602	604	PF00675	0.548
CLV_NRD_NRD_1	690	692	PF00675	0.574
CLV_NRD_NRD_1	701	703	PF00675	0.572
CLV_NRD_NRD_1	711	713	PF00675	0.604
CLV_PCSK_KEX2_1	179	181	PF00082	0.571
CLV_PCSK_KEX2_1	19	21	PF00082	0.694
CLV_PCSK_KEX2_1	212	214	PF00082	0.666
CLV_PCSK_KEX2_1	362	364	PF00082	0.686
CLV_PCSK_KEX2_1	442	444	PF00082	0.532
CLV_PCSK_KEX2_1	450	452	PF00082	0.522
CLV_PCSK_KEX2_1	480	482	PF00082	0.539
CLV_PCSK_KEX2_1	506	508	PF00082	0.586
CLV_PCSK_KEX2_1	602	604	PF00082	0.548
CLV_PCSK_KEX2_1	690	692	PF00082	0.574
CLV_PCSK_KEX2_1	701	703	PF00082	0.572
CLV_PCSK_PC1ET2_1	362	364	PF00082	0.683
CLV_PCSK_PC1ET2_1	480	482	PF00082	0.619
CLV_PCSK_SKI1_1	137	141	PF00082	0.570
CLV_PCSK_SKI1_1	22	26	PF00082	0.674
CLV_PCSK_SKI1_1	222	226	PF00082	0.647
CLV_PCSK_SKI1_1	243	247	PF00082	0.708
CLV_PCSK_SKI1_1	333	337	PF00082	0.672
CLV_PCSK_SKI1_1	422	426	PF00082	0.519
CLV_PCSK_SKI1_1	55	59	PF00082	0.479
CLV_PCSK_SKI1_1	61	65	PF00082	0.468
CLV_Separin_Metazoa	283	287	PF03568	0.677
DEG_APCC_DBOX_1	332	340	PF00400	0.661
DEG_APCC_DBOX_1	60	68	PF00400	0.570
DOC_CYCLIN_RxL_1	19	29	PF00134	0.669
DOC_MAPK_gen_1	19	27	PF00069	0.539
DOC_MAPK_gen_1	275	284	PF00069	0.615
DOC_USP7_MATH_1	361	365	PF00917	0.550
DOC_USP7_MATH_1	726	730	PF00917	0.767
DOC_USP7_MATH_1	8	12	PF00917	0.716
DOC_USP7_UBL2_3	155	159	PF12436	0.568
LIG_14-3-3_CanoR_1	161	169	PF00244	0.634
LIG_14-3-3_CanoR_1	333	341	PF00244	0.627
LIG_14-3-3_CanoR_1	379	383	PF00244	0.612
LIG_14-3-3_CanoR_1	442	446	PF00244	0.606
LIG_14-3-3_CanoR_1	681	689	PF00244	0.583
LIG_FHA_1	108	114	PF00498	0.567
LIG_FHA_1	123	129	PF00498	0.518
LIG_FHA_1	148	154	PF00498	0.578
LIG_FHA_1	180	186	PF00498	0.652
LIG_FHA_1	44	50	PF00498	0.490
LIG_FHA_1	672	678	PF00498	0.549
LIG_FHA_1	94	100	PF00498	0.634
LIG_FHA_2	161	167	PF00498	0.533
LIG_FHA_2	409	415	PF00498	0.504
LIG_FHA_2	681	687	PF00498	0.608
LIG_LIR_Gen_1	69	75	PF02991	0.606
LIG_LIR_Nem_3	69	74	PF02991	0.580
LIG_NRBOX	23	29	PF00104	0.521
LIG_RPA_C_Fungi	451	463	PF08784	0.621
LIG_SH2_STAP1	515	519	PF00017	0.346
LIG_SH2_STAP1	71	75	PF00017	0.582
LIG_SH2_STAT3	42	45	PF00017	0.499
LIG_SH2_STAT3	515	518	PF00017	0.344
LIG_SH2_STAT3	663	666	PF00017	0.613
LIG_SH2_STAT5	169	172	PF00017	0.505
LIG_SH2_STAT5	37	40	PF00017	0.601
LIG_SH2_STAT5	59	62	PF00017	0.533
LIG_SUMO_SIM_anti_2	23	29	PF11976	0.661
LIG_SUMO_SIM_anti_2	281	286	PF11976	0.601
LIG_SUMO_SIM_par_1	23	29	PF11976	0.545
LIG_TRAF2_1	130	133	PF00917	0.633
LIG_TRAF2_1	163	166	PF00917	0.609
LIG_TRAF2_1	228	231	PF00917	0.673
LIG_TRAF2_1	444	447	PF00917	0.555
LIG_TRAF2_1	684	687	PF00917	0.597
LIG_TRAF2_1	81	84	PF00917	0.461
MOD_CK1_1	618	624	PF00069	0.696
MOD_CK1_1	680	686	PF00069	0.648
MOD_CK2_1	160	166	PF00069	0.545
MOD_CK2_1	181	187	PF00069	0.601
MOD_CK2_1	362	368	PF00069	0.694
MOD_CK2_1	378	384	PF00069	0.550
MOD_CK2_1	408	414	PF00069	0.496
MOD_CK2_1	441	447	PF00069	0.619
MOD_CK2_1	638	644	PF00069	0.690
MOD_CK2_1	680	686	PF00069	0.648
MOD_Cter_Amidation	710	713	PF01082	0.590
MOD_GlcNHglycan	364	367	PF01048	0.725
MOD_GlcNHglycan	635	638	PF01048	0.751
MOD_GSK3_1	101	108	PF00069	0.647
MOD_GSK3_1	232	239	PF00069	0.709
MOD_GSK3_1	309	316	PF00069	0.638
MOD_GSK3_1	327	334	PF00069	0.585
MOD_GSK3_1	401	408	PF00069	0.541
MOD_GSK3_1	676	683	PF00069	0.587
MOD_N-GLC_1	93	98	PF02516	0.474
MOD_NEK2_1	192	197	PF00069	0.677
MOD_NEK2_1	261	266	PF00069	0.602
MOD_NEK2_1	406	411	PF00069	0.533
MOD_NEK2_1	537	542	PF00069	0.539
MOD_NEK2_1	615	620	PF00069	0.601
MOD_NEK2_1	671	676	PF00069	0.543
MOD_NEK2_1	677	682	PF00069	0.561
MOD_NEK2_1	696	701	PF00069	0.560
MOD_PIKK_1	137	143	PF00454	0.646
MOD_PIKK_1	344	350	PF00454	0.708
MOD_PIKK_1	401	407	PF00454	0.530
MOD_PIKK_1	408	414	PF00454	0.445
MOD_PIKK_1	615	621	PF00454	0.610
MOD_PIKK_1	627	633	PF00454	0.570
MOD_PK_1	232	238	PF00069	0.725
MOD_PKA_1	179	185	PF00069	0.643
MOD_PKA_1	212	218	PF00069	0.677
MOD_PKA_1	362	368	PF00069	0.727
MOD_PKA_2	160	166	PF00069	0.636
MOD_PKA_2	179	185	PF00069	0.397
MOD_PKA_2	212	218	PF00069	0.647
MOD_PKA_2	297	303	PF00069	0.583
MOD_PKA_2	314	320	PF00069	0.580
MOD_PKA_2	362	368	PF00069	0.727
MOD_PKA_2	378	384	PF00069	0.607
MOD_PKA_2	406	412	PF00069	0.635
MOD_PKA_2	441	447	PF00069	0.602
MOD_PKA_2	471	477	PF00069	0.563
MOD_PKA_2	680	686	PF00069	0.648
MOD_PKB_1	311	319	PF00069	0.611
MOD_Plk_1	232	238	PF00069	0.708
MOD_Plk_1	261	267	PF00069	0.615
MOD_Plk_1	33	39	PF00069	0.531
MOD_Plk_1	55	61	PF00069	0.503
MOD_Plk_1	561	567	PF00069	0.481
MOD_Plk_1	627	633	PF00069	0.742
MOD_Plk_2-3	181	187	PF00069	0.601
MOD_Plk_2-3	214	220	PF00069	0.693
MOD_Plk_2-3	378	384	PF00069	0.569
MOD_Plk_2-3	441	447	PF00069	0.635
MOD_Plk_4	33	39	PF00069	0.617
MOD_Plk_4	45	51	PF00069	0.454
MOD_Plk_4	471	477	PF00069	0.599
MOD_Plk_4	705	711	PF00069	0.581
MOD_SUMO_for_1	67	70	PF00179	0.613
MOD_SUMO_rev_2	208	218	PF00179	0.572
MOD_SUMO_rev_2	29	36	PF00179	0.529
MOD_SUMO_rev_2	484	492	PF00179	0.593
TRG_DiLeu_BaEn_1	23	28	PF01217	0.655
TRG_DiLeu_BaEn_1	471	476	PF01217	0.333
TRG_DiLeu_BaEn_4	187	193	PF01217	0.613
TRG_DiLeu_BaEn_4	440	446	PF01217	0.596
TRG_DiLeu_BaEn_4	570	576	PF01217	0.563
TRG_DiLeu_BaEn_4	588	594	PF01217	0.571
TRG_DiLeu_BaEn_4	83	89	PF01217	0.625
TRG_DiLeu_BaLyEn_6	673	678	PF01217	0.611
TRG_ENDOCYTIC_2	71	74	PF00928	0.624
TRG_ER_diArg_1	178	180	PF00400	0.659
TRG_ER_diArg_1	285	288	PF00400	0.673
TRG_ER_diArg_1	450	452	PF00400	0.605
TRG_ER_diArg_1	506	508	PF00400	0.557
TRG_ER_diArg_1	601	603	PF00400	0.546
TRG_ER_diArg_1	689	691	PF00400	0.565
TRG_ER_diArg_1	701	703	PF00400	0.569
TRG_Pf-PMV_PEXEL_1	22	26	PF00026	0.674
TRG_Pf-PMV_PEXEL_1	422	426	PF00026	0.501
TRG_Pf-PMV_PEXEL_1	443	447	PF00026	0.550
TRG_Pf-PMV_PEXEL_1	450	454	PF00026	0.568
TRG_Pf-PMV_PEXEL_1	485	489	PF00026	0.594
TRG_Pf-PMV_PEXEL_1	506	510	PF00026	0.651
TRG_Pf-PMV_PEXEL_1	517	521	PF00026	0.575
TRG_Pf-PMV_PEXEL_1	627	631	PF00026	0.657
TRG_Pf-PMV_PEXEL_1	701	705	PF00026	0.583

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4JQ17	Bodo saltans	33%	83%
A0A3R7LSL7	Trypanosoma rangeli	41%	78%
A4H8M2	Leishmania braziliensis	85%	100%
A4HWZ3	Leishmania infantum	97%	75%
C9ZW08	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	78%
Q4QES2	Leishmania major	95%	100%
V5B8F4	Trypanosoma cruzi	41%	78%