Sucrose-phosphate synthase-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

sucrose-phosphate synthase-like protein

Species:

Leishmania mexicana

UniProt:

E9AQQ4_LEIMU

TriTrypDb:

LmxM.16.0950

Length:

464

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

E9AQQ4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: E9AQQ4

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	8
GO:0008194	UDP-glycosyltransferase activity	4	6
GO:0016740	transferase activity	2	8
GO:0016757	glycosyltransferase activity	3	8
GO:0016758	hexosyltransferase activity	4	6
GO:0035251	UDP-glucosyltransferase activity	5	6
GO:0046524	sucrose-phosphate synthase activity	6	6
GO:0046527	glucosyltransferase activity	5	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	140	142	PF00675	0.504
CLV_NRD_NRD_1	324	326	PF00675	0.483
CLV_PCSK_KEX2_1	117	119	PF00082	0.536
CLV_PCSK_KEX2_1	140	142	PF00082	0.506
CLV_PCSK_KEX2_1	293	295	PF00082	0.426
CLV_PCSK_KEX2_1	83	85	PF00082	0.598
CLV_PCSK_PC1ET2_1	117	119	PF00082	0.536
CLV_PCSK_PC1ET2_1	293	295	PF00082	0.426
CLV_PCSK_PC1ET2_1	83	85	PF00082	0.598
CLV_PCSK_SKI1_1	185	189	PF00082	0.519
CLV_PCSK_SKI1_1	310	314	PF00082	0.483
CLV_PCSK_SKI1_1	422	426	PF00082	0.551
CLV_PCSK_SKI1_1	452	456	PF00082	0.340
DOC_CKS1_1	53	58	PF01111	0.668
DOC_MAPK_DCC_7	141	151	PF00069	0.517
DOC_MAPK_DCC_7	63	73	PF00069	0.591
DOC_MAPK_gen_1	113	123	PF00069	0.534
DOC_MAPK_gen_1	307	317	PF00069	0.537
DOC_MAPK_HePTP_8	111	123	PF00069	0.531
DOC_MAPK_MEF2A_6	114	123	PF00069	0.505
DOC_MAPK_MEF2A_6	310	317	PF00069	0.551
DOC_MAPK_NFAT4_5	310	318	PF00069	0.551
DOC_PP1_RVXF_1	279	286	PF00149	0.426
DOC_PP4_FxxP_1	128	131	PF00568	0.448
DOC_PP4_FxxP_1	343	346	PF00568	0.426
DOC_USP7_MATH_1	192	196	PF00917	0.308
DOC_USP7_MATH_1	35	39	PF00917	0.514
DOC_USP7_MATH_1	359	363	PF00917	0.476
DOC_USP7_MATH_1	79	83	PF00917	0.614
DOC_USP7_UBL2_3	113	117	PF12436	0.529
DOC_USP7_UBL2_3	307	311	PF12436	0.353
DOC_WW_Pin1_4	220	225	PF00397	0.531
DOC_WW_Pin1_4	380	385	PF00397	0.426
DOC_WW_Pin1_4	52	57	PF00397	0.596
LIG_14-3-3_CanoR_1	288	292	PF00244	0.260
LIG_14-3-3_CanoR_1	84	89	PF00244	0.535
LIG_Actin_WH2_2	324	341	PF00022	0.426
LIG_BIR_II_1	1	5	PF00653	0.571
LIG_BRCT_BRCA1_1	194	198	PF00533	0.515
LIG_Clathr_ClatBox_1	373	377	PF01394	0.426
LIG_deltaCOP1_diTrp_1	4	8	PF00928	0.514
LIG_FHA_1	103	109	PF00498	0.522
LIG_FHA_1	182	188	PF00498	0.540
LIG_FHA_1	322	328	PF00498	0.559
LIG_FHA_1	339	345	PF00498	0.298
LIG_FHA_1	381	387	PF00498	0.426
LIG_FHA_2	355	361	PF00498	0.426
LIG_FHA_2	407	413	PF00498	0.497
LIG_FHA_2	53	59	PF00498	0.669
LIG_LIR_Apic_2	12	18	PF02991	0.550
LIG_LIR_Apic_2	340	346	PF02991	0.483
LIG_LIR_Gen_1	207	216	PF02991	0.539
LIG_LIR_Gen_1	330	338	PF02991	0.551
LIG_LIR_Gen_1	4	10	PF02991	0.463
LIG_LIR_Gen_1	415	426	PF02991	0.551
LIG_LIR_Gen_1	82	93	PF02991	0.509
LIG_LIR_Nem_3	105	110	PF02991	0.522
LIG_LIR_Nem_3	207	211	PF02991	0.488
LIG_LIR_Nem_3	290	295	PF02991	0.377
LIG_LIR_Nem_3	330	336	PF02991	0.497
LIG_LIR_Nem_3	368	374	PF02991	0.426
LIG_LIR_Nem_3	4	8	PF02991	0.464
LIG_LIR_Nem_3	415	421	PF02991	0.551
LIG_LIR_Nem_3	60	65	PF02991	0.511
LIG_Pex14_2	208	212	PF04695	0.476
LIG_Pex14_2	285	289	PF04695	0.426
LIG_Pex14_2	371	375	PF04695	0.426
LIG_SH2_CRK	227	231	PF00017	0.542
LIG_SH2_CRK	279	283	PF00017	0.480
LIG_SH2_CRK	333	337	PF00017	0.481
LIG_SH2_CRK	418	422	PF00017	0.480
LIG_SH2_GRB2like	163	166	PF00017	0.480
LIG_SH2_NCK_1	356	360	PF00017	0.551
LIG_SH2_SRC	65	68	PF00017	0.544
LIG_SH2_STAP1	163	167	PF00017	0.541
LIG_SH2_STAP1	279	283	PF00017	0.480
LIG_SH2_STAT5	110	113	PF00017	0.538
LIG_SH2_STAT5	328	331	PF00017	0.437
LIG_SH2_STAT5	356	359	PF00017	0.480
LIG_SH2_STAT5	96	99	PF00017	0.551
LIG_SH3_1	210	216	PF00018	0.544
LIG_SH3_2	171	176	PF14604	0.572
LIG_SH3_3	144	150	PF00018	0.511
LIG_SH3_3	168	174	PF00018	0.583
LIG_SH3_3	197	203	PF00018	0.538
LIG_SH3_3	210	216	PF00018	0.495
LIG_SH3_3	228	234	PF00018	0.398
LIG_SUMO_SIM_par_1	130	136	PF11976	0.338
LIG_TRAF2_1	89	92	PF00917	0.542
LIG_TRFH_1	212	216	PF08558	0.611
LIG_TRFH_1	342	346	PF08558	0.426
LIG_UBA3_1	211	217	PF00899	0.437
LIG_UBA3_1	335	339	PF00899	0.260
MOD_CK1_1	321	327	PF00069	0.449
MOD_CK1_1	446	452	PF00069	0.497
MOD_CK2_1	300	306	PF00069	0.480
MOD_CK2_1	363	369	PF00069	0.426
MOD_CK2_1	406	412	PF00069	0.480
MOD_Cter_Amidation	115	118	PF01082	0.556
MOD_GlcNHglycan	189	192	PF01048	0.482
MOD_GlcNHglycan	194	197	PF01048	0.471
MOD_GlcNHglycan	200	203	PF01048	0.537
MOD_GlcNHglycan	24	27	PF01048	0.567
MOD_GlcNHglycan	389	392	PF01048	0.426
MOD_GSK3_1	255	262	PF00069	0.577
MOD_GSK3_1	359	366	PF00069	0.514
MOD_GSK3_1	43	50	PF00069	0.474
MOD_NEK2_1	198	203	PF00069	0.551
MOD_NEK2_1	255	260	PF00069	0.592
MOD_NEK2_1	338	343	PF00069	0.480
MOD_NEK2_1	445	450	PF00069	0.505
MOD_NEK2_1	457	462	PF00069	0.590
MOD_NEK2_2	359	364	PF00069	0.474
MOD_PIKK_1	255	261	PF00454	0.658
MOD_PIKK_1	318	324	PF00454	0.551
MOD_PIKK_1	345	351	PF00454	0.480
MOD_PIKK_1	446	452	PF00454	0.525
MOD_PIKK_1	457	463	PF00454	0.574
MOD_PK_1	294	300	PF00069	0.473
MOD_PKA_1	443	449	PF00069	0.540
MOD_PKA_2	181	187	PF00069	0.540
MOD_PKA_2	287	293	PF00069	0.283
MOD_Plk_1	255	261	PF00069	0.668
MOD_Plk_1	359	365	PF00069	0.551
MOD_Plk_1	91	97	PF00069	0.517
MOD_Plk_2-3	92	98	PF00069	0.558
MOD_Plk_4	294	300	PF00069	0.480
MOD_Plk_4	311	317	PF00069	0.426
MOD_Plk_4	338	344	PF00069	0.467
MOD_Plk_4	359	365	PF00069	0.494
MOD_Plk_4	43	49	PF00069	0.515
MOD_ProDKin_1	220	226	PF00069	0.529
MOD_ProDKin_1	380	386	PF00069	0.426
MOD_ProDKin_1	52	58	PF00069	0.599
MOD_SUMO_rev_2	303	313	PF00179	0.551
MOD_SUMO_rev_2	427	432	PF00179	0.480
TRG_DiLeu_BaEn_1	369	374	PF01217	0.426
TRG_DiLeu_BaEn_2	102	108	PF01217	0.526
TRG_ENDOCYTIC_2	178	181	PF00928	0.475
TRG_ENDOCYTIC_2	227	230	PF00928	0.540
TRG_ENDOCYTIC_2	252	255	PF00928	0.529
TRG_ENDOCYTIC_2	279	282	PF00928	0.480
TRG_ENDOCYTIC_2	328	331	PF00928	0.426
TRG_ENDOCYTIC_2	333	336	PF00928	0.426
TRG_ENDOCYTIC_2	418	421	PF00928	0.480
TRG_ER_diArg_1	140	142	PF00400	0.560
TRG_Pf-PMV_PEXEL_1	325	330	PF00026	0.551

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILL5	Leptomonas seymouri	80%	100%
A0A0R6YAV9	Leishmania donovani	94%	100%
A0A0S4JKT8	Bodo saltans	46%	85%
A4H8L9	Leishmania braziliensis	88%	100%
A4HWZ0	Leishmania infantum	94%	100%
Q4QES5	Leishmania major	94%	100%